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Items: 48


Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates.

Goedeke L, Peng L, Montalvo-Romeral V, Butrico GM, Dufour S, Zhang XM, Perry RJ, Cline GW, Kievit P, Chng K, Petersen KF, Shulman GI.

Sci Transl Med. 2019 Oct 2;11(512). pii: eaay0284. doi: 10.1126/scitranslmed.aay0284.


An expectation-maximization algorithm enables accurate ecological modeling using longitudinal microbiome sequencing data.

Li C, Chng KR, Kwah JS, Av-Shalom TV, Tucker-Kellogg L, Nagarajan N.

Microbiome. 2019 Aug 22;7(1):118. doi: 10.1186/s40168-019-0729-z.


A Meta-Analysis of the Utility of Preoperative Intravenous Paracetamol for Post-Caesarean Analgesia.

Ng QX, Loke W, Yeo WS, Chng KYY, Tan CH.

Medicina (Kaunas). 2019 Jul 31;55(8). pii: E424. doi: 10.3390/medicina55080424. Review.


Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes.

Bertrand D, Shaw J, Kalathiyappan M, Ng AHQ, Kumar MS, Li C, Dvornicic M, Soldo JP, Koh JY, Tong C, Ng OT, Barkham T, Young B, Marimuthu K, Chng KR, Sikic M, Nagarajan N.

Nat Biotechnol. 2019 Aug;37(8):937-944. doi: 10.1038/s41587-019-0191-2. Epub 2019 Jul 29.


The Difference between Cartilaginous and Bony Sulcus Angles for Patients with or without Patellofemoral Instability: A Systematic Review and Meta-analysis.

Tan SHS, Chng KSJ, Lim BY, Wong KL, Doshi C, Lim AKS, Hui JH.

J Knee Surg. 2019 Jan 24. doi: 10.1055/s-0038-1677541. [Epub ahead of print]


An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells.

Zhang Z, Chng KR, Lingadahalli S, Chen Z, Liu MH, Do HH, Cai S, Rinaldi N, Poh HM, Li G, Sung YY, Heng CL, Core LJ, Tan SK, Ruan X, Lis JT, Kellis M, Ruan Y, Sung WK, Cheung E.

Genome Res. 2019 Feb;29(2):223-235. doi: 10.1101/gr.230243.117. Epub 2019 Jan 3.


Cross-modal masked repetition and semantic priming in auditory lexical decision.

Chng KYT, Yap MJ, Goh WD.

Psychon Bull Rev. 2019 Apr;26(2):599-608. doi: 10.3758/s13423-018-1540-8.


Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma.

Huynh M, Pak C, Markovina S, Callander NS, Chng KS, Wuerzberger-Davis SM, Bakshi DD, Kink JA, Hematti P, Hope C, Asimakopoulos F, Rui L, Miyamoto S.

J Biol Chem. 2018 Feb 16;293(7):2452-2465. doi: 10.1074/jbc.RA117.000667. Epub 2017 Dec 26.


Effect of human milk formula with bovine colostrum supplementation on bone mineral density in infant cynomolgus macaques.

Tay N, Tan YC, Chng K, Libedinsky C, Gluckman P, Buschdorf JP.

J Dev Orig Health Dis. 2018 Apr;9(2):172-181. doi: 10.1017/S2040174417000812. Epub 2017 Oct 17.


The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat.

Yip LY, Aw CC, Lee SH, Hong YS, Ku HC, Xu WH, Chan JMX, Cheong EJY, Chng KR, Ng AHQ, Nagarajan N, Mahendran R, Lee YK, Browne ER, Chan ECY.

Hepatology. 2018 Jan;67(1):282-295. doi: 10.1002/hep.29327. Epub 2017 Nov 19.


Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys.

Shang J, Previs SF, Conarello S, Chng K, Zhu Y, Souza SC, Staup M, Chen Y, Xie D, Zycband E, Schlessinger K, Johnson VP, Arreaza G, Liu F, Levitan D, Wang L, van Heek M, Erion M, Wang Y, Kelley DE.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E235-E243. doi: 10.1152/ajpendo.00398.2016. Epub 2017 Jan 31.


Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test.

Staup M, Aoyagi G, Bayless T, Wang Y, Chng K.

J Vis Exp. 2016 Nov 13;(117). doi: 10.3791/52895.


Independent Mobility Achieved through a Wireless Brain-Machine Interface.

Libedinsky C, So R, Xu Z, Kyar TK, Ho D, Lim C, Chan L, Chua Y, Yao L, Cheong JH, Lee JH, Vishal KV, Guo Y, Chen ZN, Lim LK, Li P, Liu L, Zou X, Ang KK, Gao Y, Ng WH, Han BS, Chng K, Guan C, Je M, Yen SC.

PLoS One. 2016 Nov 1;11(11):e0165773. doi: 10.1371/journal.pone.0165773. eCollection 2016.


Asymptomatic dengue infection may trigger Guillain-Barré syndrome.

Umapathi T, Lim CS, Ooi EE, Zhang SL, Goh EJ, Tan HC, Chng KY, Willison H.

J Peripher Nerv Syst. 2016 Dec;21(4):375-377. doi: 10.1111/jns.12190. No abstract available.


Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare.

Chng KR, Tay AS, Li C, Ng AH, Wang J, Suri BK, Matta SA, McGovern N, Janela B, Wong XF, Sio YY, Au BV, Wilm A, De Sessions PF, Lim TC, Tang MB, Ginhoux F, Connolly JE, Lane EB, Chew FT, Common JE, Nagarajan N.

Nat Microbiol. 2016 Jul 11;1(9):16106. doi: 10.1038/nmicrobiol.2016.106.


INC-Seq: accurate single molecule reads using nanopore sequencing.

Li C, Chng KR, Boey EJ, Ng AH, Wilm A, Nagarajan N.

Gigascience. 2016 Aug 2;5(1):34. doi: 10.1186/s13742-016-0140-7.


Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma.

Chng KR, Chan SH, Ng AHQ, Li C, Jusakul A, Bertrand D, Wilm A, Choo SP, Tan DMY, Lim KH, Soetinko R, Ong CK, Duda DG, Dima S, Popescu I, Wongkham C, Feng Z, Yeoh KG, Teh BT, Yongvanit P, Wongkham S, Bhudhisawasdi V, Khuntikeo N, Tan P, Pairojkul C, Ngeow J, Nagarajan N.

EBioMedicine. 2016 Jun;8:195-202. doi: 10.1016/j.ebiom.2016.04.034. Epub 2016 May 6.


@MInter: automated text-mining of microbial interactions.

Lim KM, Li C, Chng KR, Nagarajan N.

Bioinformatics. 2016 Oct 1;32(19):2981-7. doi: 10.1093/bioinformatics/btw357. Epub 2016 Jun 16.


Predicting microbial interactions through computational approaches.

Li C, Lim KM, Chng KR, Nagarajan N.

Methods. 2016 Jun 1;102:12-9. doi: 10.1016/j.ymeth.2016.02.019. Epub 2016 Mar 26.


Low birth weight associates with hippocampal gene expression.

Buschdorf JP, Ong ML, Ong SX, MacIsaac JL, Chng K, Kobor MS, Meaney MJ, Holbrook JD.

Neuroscience. 2016 Mar 24;318:190-205. doi: 10.1016/j.neuroscience.2016.01.013. Epub 2016 Jan 12.


Genomic Characterization of Dehalococcoides mccartyi Strain JNA That Reductively Dechlorinates Tetrachloroethene and Polychlorinated Biphenyls.

Wang S, Chng KR, Chen C, Bedard DL, He J.

Environ Sci Technol. 2015 Dec 15;49(24):14319-25. doi: 10.1021/acs.est.5b01979. Epub 2015 Nov 24.


Left ventricular diastolic dysfunction in nonhuman primate model of dysmetabolism and diabetes.

Gu H, Liu Y, Mei S, Wang B, Sun G, Wang X, Xiao Y, Staup M, Gregoire FM, Chng K, Wang YJ.

BMC Cardiovasc Disord. 2015 Oct 30;15:141. doi: 10.1186/s12872-015-0133-y.


MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells.

Pak C, Callander NS, Young EW, Titz B, Kim K, Saha S, Chng K, Asimakopoulos F, Beebe DJ, Miyamoto S.

Integr Biol (Camb). 2015 Jun;7(6):643-54. doi: 10.1039/c5ib00071h. Epub 2015 May 22.


Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation.

Cheong CY, Chng K, Ng S, Chew SB, Chan L, Ferguson-Smith AC.

Genome Res. 2015 May;25(5):611-23. doi: 10.1101/gr.183301.114. Epub 2015 Apr 10.


Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles.

Bertrand D, Chng KR, Sherbaf FG, Kiesel A, Chia BK, Sia YY, Huang SK, Hoon DS, Liu ET, Hillmer A, Nagarajan N.

Nucleic Acids Res. 2015 Apr 20;43(7):e44. doi: 10.1093/nar/gku1393. Epub 2015 Jan 8.


Correlation between muscular and nerve signals responsible for hand grasping in non-human primates.

Sheshadri S, Kortelainen J, Nag S, Ng KA, Bazley FA, Michoud F, Patil A, Orellana J, Libedinsky C, Lahiri A, Chan L, Chng K, Cutrone A, Bossi S, Thakor NV, Delgado-Martinez I, Yen SC.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:2314-7. doi: 10.1109/EMBC.2014.6944083.


Draft Genome Sequence of Polychlorinated Biphenyl-Dechlorinating Dehalococcoides mccartyi Strain SG1, Which Carries a Circular Putative Plasmid.

Wang S, Chng KR, Wu C, Wilm A, Nagarajan N, He J.

Genome Announc. 2014 Oct 2;2(5). pii: e00901-14. doi: 10.1128/genomeA.00901-14.


Alterations to DNA methylation and expression of CXCL14 are associated with suboptimal birth outcomes.

Cheong CY, Chng K, Lim MK, Amrithraj AI, Joseph R, Sukarieh R, Chee Tan Y, Chan L, Tan JH, Chen L, Pan H, Holbrook JD, Meaney MJ, Seng Chong Y, Gluckman PD, Stünkel W.

J Hum Genet. 2014 Sep;59(9):504-11. doi: 10.1038/jhg.2014.63. Epub 2014 Aug 7.


Genomic characterization of three unique Dehalococcoides that respire on persistent polychlorinated biphenyls.

Wang S, Chng KR, Wilm A, Zhao S, Yang KL, Nagarajan N, He J.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12103-8. doi: 10.1073/pnas.1404845111. Epub 2014 Jul 15.


Infinium monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis).

Ong ML, Tan PY, MacIsaac JL, Mah SM, Buschdorf JP, Cheong CY, Stunkel W, Chan L, Gluckman PD, Chng K, Kobor MS, Meaney MJ, Holbrook JD.

G3 (Bethesda). 2014 May 8;4(7):1227-34. doi: 10.1534/g3.114.010967.


DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation.

Das R, Lee YK, Strogantsev R, Jin S, Lim YC, Ng PY, Lin XM, Chng K, Yeo GSh, Ferguson-Smith AC, Ding C.

BMC Genomics. 2013 Oct 5;14:685. doi: 10.1186/1471-2164-14-685.


Decreased hippocampal mineralocorticoid:glucocorticoid receptor ratio is associated with low birth weight in female cynomolgus macaque neonates.

Ong SX, Chng K, Meaney MJ, Buschdorf JP.

J Mol Endocrinol. 2013 May 28;51(1):59-67. doi: 10.1530/JME-12-0218. Print 2013.


Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions.

Aziz A, Baxter EJ, Edwards C, Cheong CY, Ito M, Bench A, Kelley R, Silber Y, Beer PA, Chng K, Renfree MB, McEwen K, Gray D, Nangalia J, Mufti GJ, Hellstrom-Lindberg E, Kiladjian JJ, McMullin MF, Campbell PJ, Ferguson-Smith AC, Green AR.

J Clin Invest. 2013 May;123(5):2169-82. doi: 10.1172/JCI66113. Epub 2013 Apr 1.


A chinese new year rash.

Keah Sh, Chng K.

Malays Fam Physician. 2013 Aug 31;8(2):62-4. eCollection 2013. No abstract available.


Sequencing the transcriptional network of androgen receptor in prostate cancer.

Chng KR, Cheung E.

Cancer Lett. 2013 Nov 1;340(2):254-60. doi: 10.1016/j.canlet.2012.11.009. Epub 2012 Nov 27. Review.


A transcriptional repressor co-regulatory network governing androgen response in prostate cancers.

Chng KR, Chang CW, Tan SK, Yang C, Hong SZ, Sng NY, Cheung E.

EMBO J. 2012 Jun 13;31(12):2810-23. doi: 10.1038/emboj.2012.112. Epub 2012 Apr 24.


Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding.

Clarke IJ, Smith JT, Henry BA, Oldfield BJ, Stefanidis A, Millar RP, Sari IP, Chng K, Fabre-Nys C, Caraty A, Ang BT, Chan L, Fraley GS.

Neuroendocrinology. 2012;95(4):305-16. doi: 10.1159/000332822. Epub 2012 Jan 25. Erratum in: Neuroendocrinology. 2013;97(2):202.


Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival.

Tan PY, Chang CW, Chng KR, Wansa KD, Sung WK, Cheung E.

Mol Cell Biol. 2012 Jan;32(2):399-414. doi: 10.1128/MCB.05958-11. Epub 2011 Nov 14.


Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range.

Emerald BS, Chng K, Masuda S, Sloboda DM, Vickers MH, Kambadur R, Gluckman PD.

BMC Genomics. 2011 Oct 16;12:509. doi: 10.1186/1471-2164-12-509.


AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription.

Tan SK, Lin ZH, Chang CW, Varang V, Chng KR, Pan YF, Yong EL, Sung WK, Cheung E.

EMBO J. 2011 May 13;30(13):2569-81. doi: 10.1038/emboj.2011.151. Erratum in: EMBO J. 2011;30(13):2750. Sung, Win King [corrected to Sung, Wing Kin].


Exercise-Induced Rhabdomyolysis with Acute Renal Failure After Strenuous Push-UPS.

Keah Sh, Chng K.

Malays Fam Physician. 2009 Apr 30;4(1):37-9. eCollection 2009. No abstract available.


Improved granulocyte colony-stimulating factor mobilization of hemopoietic progenitors using cytokine combinations in primates.

Larsen SR, Chng K, Battah F, Martiniello-Wilks R, Rasko JE.

Stem Cells. 2008 Nov;26(11):2974-80. doi: 10.1634/stemcells.2008-0560. Epub 2008 Aug 21.


Notes for primary care teachers: mentoring - a personal experience.

Chng K.

Malays Fam Physician. 2007 Aug 31;2(2):79-80. eCollection 2007. No abstract available.


Antimicrobial susceptibility of community-acquired uropathogens in general practice.

Keah Sh, Wee E, Chng K, Keah K.

Malays Fam Physician. 2007 Aug 31;2(2):64-9. eCollection 2007.


Specific adeno-associated virus serotypes facilitate efficient gene transfer into human and non-human primate mesenchymal stromal cells.

Chng K, Larsen SR, Zhou S, Wright JF, Martiniello-Wilks R, Rasko JE.

J Gene Med. 2007 Jan;9(1):22-32.


Extremes of foetal birthweight for gestation in infants of diabetic mothers.

Kek LP, Ng CS, Chng KP, Ratnam SS, Cheah JS, Yeo PB, Gwee HM, Thai AC, Tan KL, Joseph R.

Ann Acad Med Singapore. 1985 Apr;14(2):303-6.


Combined team management of diabetes mellitus in pregnancy.

Ng CS, Lim LS, Chng KP, Lim P, Cheah JS, Yeo PP, Gwee HM, Tan KL, Joseph R, Yong YM.

Ann Acad Med Singapore. 1985 Apr;14(2):297-302.


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