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Items: 1 to 50 of 54

1.

Genetic tool development in marine protists: emerging model organisms for experimental cell biology.

Faktorová D, Nisbet RER, Fernández Robledo JA, Casacuberta E, Sudek L, Allen AE, Ares M Jr, Aresté C, Balestreri C, Barbrook AC, Beardslee P, Bender S, Booth DS, Bouget FY, Bowler C, Breglia SA, Brownlee C, Burger G, Cerutti H, Cesaroni R, Chiurillo MA, Clemente T, Coles DB, Collier JL, Cooney EC, Coyne K, Docampo R, Dupont CL, Edgcomb V, Einarsson E, Elustondo PA, Federici F, Freire-Beneitez V, Freyria NJ, Fukuda K, García PA, Girguis PR, Gomaa F, Gornik SG, Guo J, Hampl V, Hanawa Y, Haro-Contreras ER, Hehenberger E, Highfield A, Hirakawa Y, Hopes A, Howe CJ, Hu I, Ibañez J, Irwin NAT, Ishii Y, Janowicz NE, Jones AC, Kachale A, Fujimura-Kamada K, Kaur B, Kaye JZ, Kazana E, Keeling PJ, King N, Klobutcher LA, Lander N, Lassadi I, Li Z, Lin S, Lozano JC, Luan F, Maruyama S, Matute T, Miceli C, Minagawa J, Moosburner M, Najle SR, Nanjappa D, Nimmo IC, Noble L, Novák Vanclová AMG, Nowacki M, Nuñez I, Pain A, Piersanti A, Pucciarelli S, Pyrih J, Rest JS, Rius M, Robertson D, Ruaud A, Ruiz-Trillo I, Sigg MA, Silver PA, Slamovits CH, Jason Smith G, Sprecher BN, Stern R, Swart EC, Tsaousis AD, Tsypin L, Turkewitz A, Turnšek J, Valach M, Vergé V, von Dassow P, von der Haar T, Waller RF, Wang L, Wen X, Wheeler G, Woods A, Zhang H, Mock T, Worden AZ, Lukeš J.

Nat Methods. 2020 Apr 6. doi: 10.1038/s41592-020-0796-x. [Epub ahead of print]

PMID:
32251396
2.

CRISPR/Cas9 Technology Applied to the Study of Proteins Involved in Calcium Signaling in Trypanosoma cruzi.

Lander N, Chiurillo MA, Docampo R.

Methods Mol Biol. 2020;2116:177-197. doi: 10.1007/978-1-0716-0294-2_13.

PMID:
32221922
3.

State-of-the-art CRISPR/Cas9 Technology for Genome Editing in Trypanosomatids.

Lander N, Chiurillo MA.

J Eukaryot Microbiol. 2019 Nov;66(6):981-991. doi: 10.1111/jeu.12747. Epub 2019 Jul 7. Review.

PMID:
31211904
4.

Functional analysis and importance for host cell infection of the Ca2+-conducting subunits of the mitochondrial calcium uniporter of Trypanosoma cruzi.

Chiurillo MA, Lander N, Bertolini MS, Vercesi AE, Docampo R.

Mol Biol Cell. 2019 Jul 1;30(14):1676-1690. doi: 10.1091/mbc.E19-03-0152. Epub 2019 May 15.

5.

MICU1 and MICU2 Play an Essential Role in Mitochondrial Ca2+ Uptake, Growth, and Infectivity of the Human Pathogen Trypanosoma cruzi.

Bertolini MS, Chiurillo MA, Lander N, Vercesi AE, Docampo R.

mBio. 2019 May 7;10(3). pii: e00348-19. doi: 10.1128/mBio.00348-19.

6.

Genome Editing by CRISPR/Cas9 in Trypanosoma cruzi.

Lander N, Chiurillo MA, Docampo R.

Methods Mol Biol. 2019;1955:61-76. doi: 10.1007/978-1-4939-9148-8_5.

PMID:
30868519
7.

Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi.

Lander N, Chiurillo MA, Bertolini MS, Storey M, Vercesi AE, Docampo R.

J Biol Chem. 2018 Nov 9;293(45):17402-17417. doi: 10.1074/jbc.RA118.004498. Epub 2018 Sep 19.

8.

The mitochondrial calcium uniporter complex in trypanosomes.

Lander N, Chiurillo MA, Bertolini MS, Docampo R, Vercesi AE.

Cell Biol Int. 2018 Jun;42(6):656-663. doi: 10.1002/cbin.10928. Epub 2018 Jan 25. Review.

9.

Endogenous C-terminal Tagging by CRISPR/Cas9 in Trypanosoma cruzi.

Lander N, Chiurillo MA, Vercesi AE, Docampo R.

Bio Protoc. 2017 May 20;7(10). pii: e2299. doi: 10.21769/BioProtoc.2299.

10.

Different Roles of Mitochondrial Calcium Uniporter Complex Subunits in Growth and Infectivity of Trypanosoma cruzi.

Chiurillo MA, Lander N, Bertolini MS, Storey M, Vercesi AE, Docampo R.

mBio. 2017 May 9;8(3). pii: e00574-17. doi: 10.1128/mBio.00574-17.

11.

Subtelomeric I-SceI-Mediated Double-Strand Breaks Are Repaired by Homologous Recombination in Trypanosoma cruzi.

Chiurillo MA, Moraes Barros RR, Souza RT, Marini MM, Antonio CR, Cortez DR, Curto MÁ, Lorenzi HA, Schijman AG, Ramirez JL, da Silveira JF.

Front Microbiol. 2016 Dec 22;7:2041. doi: 10.3389/fmicb.2016.02041. eCollection 2016.

12.

CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor.

Lander N, Chiurillo MA, Storey M, Vercesi AE, Docampo R.

J Biol Chem. 2016 Dec 2;291(49):25505-25515. Epub 2016 Oct 28.

13.

TCF7L2 rs7903146 polymorphism is associated with gastric cancer: A case-control study in the Venezuelan population.

Torres K, Labrador L, Valderrama E, Chiurillo MA.

World J Gastroenterol. 2016 Jul 28;22(28):6520-6. doi: 10.3748/wjg.v22.i28.6520.

14.

Genome Editing by CRISPR/Cas9: A Game Change in the Genetic Manipulation of Protists.

Lander N, Chiurillo MA, Docampo R.

J Eukaryot Microbiol. 2016 Sep;63(5):679-90. doi: 10.1111/jeu.12338. Epub 2016 Jul 15. Review.

15.

The diversity and expansion of the trans-sialidase gene family is a common feature in Trypanosoma cruzi clade members.

Chiurillo MA, Cortez DR, Lima FM, Cortez C, Ramírez JL, Martins AG, Serrano MG, Teixeira MM, da Silveira JF.

Infect Genet Evol. 2016 Jan;37:266-74. doi: 10.1016/j.meegid.2015.11.024. Epub 2015 Dec 2.

PMID:
26640033
16.

Design of an allele-specific PCR assay to genotype the rs12255372 SNP in a pilot study of association between common TCF7L2 polymorphisms and type 2 diabetes in Venezuelans.

Moran Y, Labrador L, Camargo ME, Fernández D, Chiurillo MA.

Arch Endocrinol Metab. 2015 Jul 21;60(3):246-51. doi: 10.1590/2359-3997000000064.

17.

Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review.

Chiurillo MA.

World J Exp Med. 2015 May 20;5(2):84-102. doi: 10.5493/wjem.v5.i2.84. eCollection 2015 May 20. Review.

18.

Association of common variants on chromosome 8q24 with gastric cancer in Venezuelan patients.

Labrador L, Torres K, Camargo M, Santiago L, Valderrama E, Chiurillo MA.

Gene. 2015 Jul 15;566(1):120-4. doi: 10.1016/j.gene.2015.04.081. Epub 2015 May 2.

PMID:
25939847
19.

Genomic biomarkers related to drug response in Venezuelan populations.

Chiurillo MA.

Drug Metab Pers Ther. 2015 Mar;30(1):33-41. doi: 10.1515/dmdi-2014-0019. Review.

PMID:
25252750
20.

Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli.

Stoco PH, Wagner G, Talavera-Lopez C, Gerber A, Zaha A, Thompson CE, Bartholomeu DC, Lückemeyer DD, Bahia D, Loreto E, Prestes EB, Lima FM, Rodrigues-Luiz G, Vallejo GA, Filho JF, Schenkman S, Monteiro KM, Tyler KM, de Almeida LG, Ortiz MF, Chiurillo MA, de Moraes MH, Cunha Ode L, Mendonça-Neto R, Silva R, Teixeira SM, Murta SM, Sincero TC, Mendes TA, Urmenyi TP, Silva VG, DaRocha WD, Andersson B, Romanha AJ, Steindel M, de Vasconcelos AT, Grisard EC.

PLoS Negl Trop Dis. 2014 Sep 18;8(9):e3176. doi: 10.1371/journal.pntd.0003176. eCollection 2014 Sep.

21.

Study of the oipA genetic diversity and EPIYA motif patterns in cagA-positive Helicobacter pylori strains from Venezuelan patients with chronic gastritis.

Torres K, Valderrama E, Sayegh M, Ramírez JL, Chiurillo MA.

Microb Pathog. 2014 Nov;76:26-32. doi: 10.1016/j.micpath.2014.09.006. Epub 2014 Sep 16.

PMID:
25223715
22.

Exploring iris colour prediction and ancestry inference in admixed populations of South America.

Freire-Aradas A, Ruiz Y, Phillips C, Maroñas O, Söchtig J, Tato AG, Dios JÁ, de Cal MC, Silbiger VN, Luchessi AD, Luchessi AD, Chiurillo MA, Carracedo Á, Lareu MV.

Forensic Sci Int Genet. 2014 Nov;13:3-9. doi: 10.1016/j.fsigen.2014.06.007. Epub 2014 Jul 3.

PMID:
25051225
23.

Role of gene polymorphisms in gastric cancer and its precursor lesions: current knowledge and perspectives in Latin American countries.

Chiurillo MA.

World J Gastroenterol. 2014 Apr 28;20(16):4503-15. doi: 10.3748/wjg.v20.i16.4503. Review.

24.

Perception of the usefulness of drug/gene pairs and barriers for pharmacogenomics in Latin America.

Quinones LA, Lavanderos MA, Cayun JP, Garcia-Martin E, Agundez JA, Caceres DD, Roco AM, Morales JE, Herrera L, Encina G, Isaza CA, Redal MA, Larovere L, Soria NW, Eslava-Schmalbach J, Castaneda-Hernandez G, Lopez-Cortes A, Magno LA, Lopez M, Chiurillo MA, Rodeiro I, Castro de Guerra D, Teran E, Estevez-Carrizo F, Lares-Assef I.

Curr Drug Metab. 2014 Feb;15(2):202-8.

PMID:
24524664
25.

Distribution of GSTM1, GSTT1, GSTP1 and TP53 disease-associated gene variants in native and urban Venezuelan populations.

Chiurillo MA, Griman P, Santiago L, Torres K, Moran Y, Borjas L.

Gene. 2013 Nov 15;531(1):106-11. doi: 10.1016/j.gene.2013.08.055. Epub 2013 Aug 27.

PMID:
23994684
26.

Can the prevalence of symptoms in patients with inflammatory bowel disease be predicted by the analysis of multidrug resistance gene 1 polymorphisms?

Chiurillo MA.

Saudi J Gastroenterol. 2013 Jul-Aug;19(4):139-40. doi: 10.4103/1319-3767.114502. No abstract available.

27.

Genotyping of Helicobacter pylori virulence-associated genes shows high diversity of strains infecting patients in western Venezuela.

Chiurillo MA, Moran Y, Cañas M, Valderrama E, Granda N, Sayegh M, Ramírez JL.

Int J Infect Dis. 2013 Sep;17(9):e750-6. doi: 10.1016/j.ijid.2013.03.004. Epub 2013 Apr 20.

28.

Anatomy and evolution of telomeric and subtelomeric regions in the human protozoan parasite Trypanosoma cruzi.

Moraes Barros RR, Marini MM, Antônio CR, Cortez DR, Miyake AM, Lima FM, Ruiz JC, Bartholomeu DC, Chiurillo MA, Ramirez JL, da Silveira JF.

BMC Genomics. 2012 Jun 8;13:229. doi: 10.1186/1471-2164-13-229.

29.

Analysis of the SNPforID 52-plex markers in four Native American populations from Venezuela.

Ruiz Y, Chiurillo MA, Borjas L, Phillips C, Lareu MV, Carracedo Á.

Forensic Sci Int Genet. 2012 Sep;6(5):e142-5. doi: 10.1016/j.fsigen.2012.02.007. Epub 2012 Mar 27.

PMID:
22459951
30.

CYP2D6 gene variants in urban/admixed and Amerindian populations of Venezuela: pharmacogenetics and anthropological implications.

Griman P, Moran Y, Valero G, Loreto M, Borjas L, Chiurillo MA.

Ann Hum Biol. 2012 Mar;39(2):137-42. doi: 10.3109/03014460.2012.656703.

PMID:
22324840
31.

Infection with specific Helicobacter pylori-cag pathogenicity island strains is associated with interleukin-1B gene polymorphisms in Venezuelan chronic gastritis patients.

Chiurillo MA, Moran YH, Cañas M, Valderrama EJ, Armanie E.

Dig Dis Sci. 2011 Feb;56(2):449-56. doi: 10.1007/s10620-010-1316-0. Epub 2010 Jun 29.

PMID:
20585978
32.

Combination of Helicobacter pylori-iceA2 and proinflammatory interleukin-1 polymorphisms is associated with the severity of histological changes in Venezuelan chronic gastritis patients.

Chiurillo MA, Moran Y, Cañas M, Valderrama E, Alvarez A, Armanie E.

FEMS Immunol Med Microbiol. 2010 Jul 1;59(2):170-6. doi: 10.1111/j.1574-695X.2010.00675.x. Epub 2010 Apr 2.

33.

[TP53 codon 72 polymorphism and gastric cancer risk: a case-control study in individuals from the central-western region of Venezuela].

Cañas M, Morán Y, Camargo ME, Rivero MB, Bohórquez A, Villegas V, Ramírez E, Rendón Y, Suárez A, Morales L, Useche E, Salazar S, Zambrano A, Ramírez A, Valderrama E, Briceño Z, Chiurillo MA.

Invest Clin. 2009 Jun;50(2):153-61. Spanish.

PMID:
19662811
34.

Molecular analysis of surface glycoprotein multigene family TrGP expressed on the plasma membrane of Trypanosoma rangeli epimastigotes forms.

Peña CP, Lander N, Rodríguez E, Crisante G, Añez N, Ramírez JL, Chiurillo MA.

Acta Trop. 2009 Sep;111(3):255-62. doi: 10.1016/j.actatropica.2009.05.003. Epub 2009 May 9.

PMID:
19433050
35.

[Interleukin-1 genetic polymorphism: association with gastric cancer in the high-risk Central-Western population of Venezuela].

Cañas M, Morán Y, Rivero MB, Bohórquez A, Villegas V, Rendón Y, Ramírez E, Valderrama E, Briceño Z, Chiurillo MA.

Rev Med Chil. 2009 Jan;137(1):63-70. doi: /S0034-98872009000100009. Epub 2009 Apr 23. Spanish.

36.

Haplotype diversity in human mitochondrial DNA hypervariable regions I-III in the city of Caracas (Venezuela).

Lander N, Rojas MG, Chiurillo MA, Ramírez JL.

Forensic Sci Int Genet. 2008 Sep;2(4):e61-4. doi: 10.1016/j.fsigen.2007.12.009. Epub 2008 Feb 14.

PMID:
19083830
37.

[Chemiluminescent measurement of telomere DNA content in archival biopsies of colon adenocarcinoma].

Morán Y, Valderrama E, Camargo ME, Rivero MB, Chiurillo MA.

Invest Clin. 2007 Dec;48(4):485-93. Spanish.

PMID:
18271393
38.

Usefulness of 12 Y-STRs for forensic genetics evaluation in two populations from Venezuela.

Borjas L, Bernal LP, Chiurillo MA, Tovar F, Zabala W, Lander N, Ramírez JL.

Leg Med (Tokyo). 2008 Mar;10(2):107-12. Epub 2007 Nov 5.

PMID:
17981491
39.

Kinetic and molecular evidences that human cardiac muscle express non-M2 muscarinic receptor subtypes that are able to interact themselves.

Pérez CC, Tobar ID, Jiménez E, Castañeda D, Rivero MB, Concepción JL, Chiurillo MA, Bonfante-Cabarcas R.

Pharmacol Res. 2006 Nov;54(5):345-55. Epub 2006 Jul 8.

PMID:
16965921
40.

A new allele of the short tandem repeat locus D21S11 in a Venezuelan population.

Lander N, Tovar F, Chiurillo MA, Ramírez JL.

J Forensic Sci. 2006 May;51(3):695. No abstract available.

PMID:
16696726
41.

Genetic variation of 15 STR autosomal loci in the Maracaibo population from Venezuela.

Bernal LP, Borjas L, Zabala W, Portillo MG, Fernández E, Delgado W, Tovar F, Lander N, Chiurillo MA, Ramírez JL, García O.

Forensic Sci Int. 2006 Aug 10;161(1):60-3. Epub 2005 Sep 6.

PMID:
16143477
42.

Trypanosoma rangeli expresses a gene of the group II trans-sialidase superfamily.

Añez-Rojas N, Peralta A, Crisante G, Rojas A, Añez N, Ramírez JL, Chiurillo MA.

Mol Biochem Parasitol. 2005 Jul;142(1):133-6. Epub 2005 Apr 9. No abstract available.

PMID:
15907566
43.
44.

Telomere and subtelomere of Trypanosoma cruzi chromosomes are enriched in (pseudo)genes of retrotransposon hot spot and trans-sialidase-like gene families: the origins of T. cruzi telomeres.

Kim D, Chiurillo MA, El-Sayed N, Jones K, Santos MR, Porcile PE, Andersson B, Myler P, da Silveira JF, Ramírez JL.

Gene. 2005 Feb 14;346:153-61. Epub 2005 Jan 28.

PMID:
15716016
45.

Genetic profiling of a central Venezuelan population using 15 STR markers that may be of forensic importance.

Chiurillo MA, Morales A, Mendes AM, Lander N, Tovar F, Fuentes A, Ramírez JL.

Forensic Sci Int. 2003 Sep 9;136(1-3):99-101.

PMID:
12969630
46.

Detection of Trypanosoma cruzi and Trypanosoma rangeli infection by duplex PCR assay based on telomeric sequences.

Chiurillo MA, Crisante G, Rojas A, Peralta A, Dias M, Guevara P, Añez N, Ramírez JL.

Clin Diagn Lab Immunol. 2003 Sep;10(5):775-9.

47.

An improved general approach for cloning and characterizing telomeres: the protozoan parasite Trypanosoma cruzi as model organism.

Chiurillo MA, Santos MR, Franco Da Silveira J, Ramírez JL.

Gene. 2002 Jul 10;294(1-2):197-204.

PMID:
12234681
48.

Charaterization of Leishmania major Friedlin telomeric terminus.

Chiurillo MA, Ramírez JL.

Mem Inst Oswaldo Cruz. 2002 Apr;97(3):343-6.

49.

Comparative study of Trypanosoma rangeli and Trypanosoma cruzi telomeres.

Chiurillo MA, Peralta A, Ramírez JL.

Mol Biochem Parasitol. 2002 Apr 9;120(2):305-8. No abstract available.

PMID:
11897137
50.

Detection of Leishmania causing visceral leishmaniasis in the Old and New Worlds by a polymerase chain reaction assay based on telomeric sequences.

Chiurillo MA, Sachdeva M, Dole VS, Yepes Y, Miliani E, Vazquez L, Rojas A, Crisante G, Guevara P, Añez N, Madhubala R, Ramírez JL.

Am J Trop Med Hyg. 2001 Nov;65(5):573-82.

PMID:
11716117

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