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Items: 34


Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases.

Akoumianakis I, Sanna F, Margaritis M, Badi I, Akawi N, Herdman L, Coutinho P, Fagan H, Antonopoulos AS, Oikonomou EK, Thomas S, Chiu AP, Chuaiphichai S, Kotanidis CP, Christodoulides C, Petrou M, Krasopoulos G, Sayeed R, Lv L, Hale A, Naeimi Kararoudi M, McNeill E, Douglas G, George S, Tousoulis D, Channon KM, Antoniades C.

Sci Transl Med. 2019 Sep 18;11(510). pii: eaav5055. doi: 10.1126/scitranslmed.aav5055.


Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.

Zhang SJ, Li XX, Yu Y, Chiu AP, Lo LH, To JC, Rowlands DK, Keng VW.

Biochem Biophys Res Commun. 2019 Jul 12;515(1):50-56. doi: 10.1016/j.bbrc.2019.05.014. Epub 2019 May 21.


HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism.

Chiu AP, Tschida BR, Sham TT, Lo LH, Moriarity BS, Li XX, Lo RC, Hinton DE, Rowlands DK, Chan CO, Mok DKW, Largaespada DA, Warner N, Keng VW.

Mol Cancer Res. 2019 Jul;17(7):1582-1593. doi: 10.1158/1541-7786.MCR-18-1127. Epub 2019 Apr 11.


Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation.

Li XX, Lu XY, Zhang SJ, Chiu AP, Lo LH, Largaespada DA, Chen QB, Keng VW.

Biomed Pharmacother. 2019 Mar;111:68-75. doi: 10.1016/j.biopha.2018.12.019. Epub 2018 Dec 18.


Liver-Specific Delivery of Sleeping Beauty Transposon System by Hydrodynamic Injection for Cancer Gene Validation.

Chiu AP, Keng VW.

Methods Mol Biol. 2019;1907:185-196. doi: 10.1007/978-1-4939-8967-6_15.


Conditional Inactivation of Nf1 and Pten in Schwann Cells Results in Abnormal Neuromuscular Junction Maturation.

Li XX, Zhang SJ, Chiu AP, Lo LH, To JC, Cui HN, Rowlands DK, Keng VW.

G3 (Bethesda). 2019 Jan 9;9(1):297-303. doi: 10.1534/g3.118.200795.


Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor.

Li XX, Zhang SJ, Chiu AP, Lo LH, Huang J, Rowlands DK, Wang J, Keng VW.

Cancer Med. 2018 Sep;7(9):4791-4800. doi: 10.1002/cam4.1732. Epub 2018 Aug 15.


Modeling the spread of Middle East respiratory syndrome coronavirus in Saudi Arabia.

Lin Q, Chiu AP, Zhao S, He D.

Stat Methods Med Res. 2018 Jul;27(7):1968-1978. doi: 10.1177/0962280217746442.


Modelling the skip-and-resurgence of Japanese encephalitis epidemics in Hong Kong.

Zhao S, Lou Y, Chiu APY, He D.

J Theor Biol. 2018 Oct 7;454:1-10. doi: 10.1016/j.jtbi.2018.05.017. Epub 2018 May 21.


Unsynchronized influenza epidemics in two neighboring subtropical cities.

Tang X, Fang S, Chiu APY, Lin Q, Tang EYN, Wang X, He D.

Int J Infect Dis. 2018 Apr;69:85-87. doi: 10.1016/j.ijid.2018.02.019. Epub 2018 Mar 3.


HIV epidemics in Shenzhen and Chongqing, China.

Yang S, Chiu APY, Lin Q, Zeng Z, Li Y, Zhang Y, Yang Z, Yang L, He D.

PLoS One. 2018 Feb 15;13(2):e0192849. doi: 10.1371/journal.pone.0192849. eCollection 2018.


Analysing increasing trends of Guillain-Barré Syndrome (GBS) and dengue cases in Hong Kong using meteorological data.

Tang X, Zhao S, Chiu APY, Wang X, Yang L, He D.

PLoS One. 2017 Dec 4;12(12):e0187830. doi: 10.1371/journal.pone.0187830. eCollection 2017.


Anti-phase synchronization of influenza A/H1N1 and A/H3N2 in Hong Kong and countries in the North Temperate Zone.

Chiu APY, Lin Q, Tang EYN, He D.

Int J Infect Dis. 2018 Jan;66:42-44. doi: 10.1016/j.ijid.2017.11.006. Epub 2017 Nov 11.


Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain.

Page MM, Skovsø S, Cen H, Chiu AP, Dionne DA, Hutchinson DF, Lim GE, Szabat M, Flibotte S, Sinha S, Nislow C, Rodrigues B, Johnson JD.

FASEB J. 2018 Mar;32(3):1196-1206. doi: 10.1096/fj.201700518R. Epub 2018 Jan 3.


Patterns of influenza vaccination coverage in the United States from 2009 to 2015.

Chiu APY, Dushoff J, Yu D, He D.

Int J Infect Dis. 2017 Dec;65:122-127. doi: 10.1016/j.ijid.2017.10.004. Epub 2017 Oct 16.


Dual effects of hyperglycemia on endothelial cells and cardiomyocytes to enhance coronary LPL activity.

Chiu AP, Bierende D, Lal N, Wang F, Wan A, Vlodavsky I, Hussein B, Rodrigues B.

Am J Physiol Heart Circ Physiol. 2018 Jan 1;314(1):H82-H94. doi: 10.1152/ajpheart.00372.2017. Epub 2017 Oct 6.


News trends and web search query of HIV/AIDS in Hong Kong.

Chiu APY, Lin Q, He D.

PLoS One. 2017 Sep 18;12(9):e0185004. doi: 10.1371/journal.pone.0185004. eCollection 2017.


Effects of reactive social distancing on the 1918 influenza pandemic.

Yu D, Lin Q, Chiu AP, He D.

PLoS One. 2017 Jul 12;12(7):e0180545. doi: 10.1371/journal.pone.0180545. eCollection 2017.


Modelling the transmission and control strategies of varicella among school children in Shenzhen, China.

Tang X, Zhao S, Chiu APY, Ma H, Xie X, Mei S, Kong D, Qin Y, Chen Z, Wang X, He D.

PLoS One. 2017 May 18;12(5):e0177514. doi: 10.1371/journal.pone.0177514. eCollection 2017.


Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.

Lal N, Chiu AP, Wang F, Zhang D, Jia J, Wan A, Vlodavsky I, Hussein B, Rodrigues B.

Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1163-H1175. doi: 10.1152/ajpheart.00659.2016. Epub 2017 Mar 17.


Different responses of influenza epidemic to weather factors among Shanghai, Hong Kong, and British Columbia.

Wang XL, Yang L, He DH, Chiu AP, Chan KH, Chan KP, Zhou M, Wong CM, Guo Q, Hu W.

Int J Biometeorol. 2017 Jun;61(6):1043-1053. doi: 10.1007/s00484-016-1284-y. Epub 2017 Feb 8.


Spatio-temporal patterns of proportions of influenza B cases.

He D, Chiu AP, Lin Q, Yu D.

Sci Rep. 2017 Jan 9;7:40085. doi: 10.1038/srep40085.


Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.

Zhang D, Wang F, Lal N, Chiu AP, Wan A, Jia J, Bierende D, Flibotte S, Sinha S, Asadi A, Hu X, Taghizadeh F, Pulinilkunnil T, Nislow C, Vlodavsky I, Johnson JD, Kieffer TJ, Hussein B, Rodrigues B.

Diabetes. 2017 Jan;66(1):45-57. doi: 10.2337/db16-0761. Epub 2016 Oct 7.


High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature.

Wang F, Jia J, Lal N, Zhang D, Chiu AP, Wan A, Vlodavsky I, Hussein B, Rodrigues B.

Cardiovasc Res. 2016 Dec;112(3):656-668.


Cardiomyocyte-endothelial cell control of lipoprotein lipase.

Chiu AP, Wan A, Rodrigues B.

Biochim Biophys Acta. 2016 Oct;1861(10):1434-41. doi: 10.1016/j.bbalip.2016.03.016. Epub 2016 Mar 17. Review.


Seasonality of Influenza A(H7N9) Virus in China-Fitting Simple Epidemic Models to Human Cases.

Lin Q, Lin Z, Chiu AP, He D.

PLoS One. 2016 Mar 10;11(3):e0151333. doi: 10.1371/journal.pone.0151333. eCollection 2016.


Cardiomyocyte VEGF Regulates Endothelial Cell GPIHBP1 to Relocate Lipoprotein Lipase to the Coronary Lumen During Diabetes Mellitus.

Chiu AP, Wan A, Lal N, Zhang D, Wang F, Vlodavsky I, Hussein B, Rodrigues B.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):145-55. doi: 10.1161/ATVBAHA.115.306774. Epub 2015 Nov 19.


Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

Chiu AP, Tschida BR, Lo LH, Moriarity BS, Rowlands DK, Largaespada DA, Keng VW.

World J Gastroenterol. 2015 Nov 14;21(42):12157-70. doi: 10.3748/wjg.v21.i42.12157. Review.


Differences in the seasonality of Middle East respiratory syndrome coronavirus and influenza in the Middle East.

He D, Chiu AP, Lin Q, Cowling BJ.

Int J Infect Dis. 2015 Nov;40:15-6. doi: 10.1016/j.ijid.2015.09.012. Epub 2015 Sep 28. No abstract available.


Endothelial cell heparanase taken up by cardiomyocytes regulates lipoprotein lipase transfer to the coronary lumen after diabetes.

Wang Y, Chiu AP, Neumaier K, Wang F, Zhang D, Hussein B, Lal N, Wan A, Liu G, Vlodavsky I, Rodrigues B.

Diabetes. 2014 Aug;63(8):2643-55. doi: 10.2337/db13-1842. Epub 2014 Mar 7.


Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase.

Zhang D, Wan A, Chiu AP, Wang Y, Wang F, Neumaier K, Lal N, Bround MJ, Johnson JD, Vlodavsky I, Rodrigues B.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2830-8. doi: 10.1161/ATVBAHA.113.302222. Epub 2013 Oct 10.


Endothelial heparanase regulates heart metabolism by stimulating lipoprotein lipase secretion from cardiomyocytes.

Wang Y, Zhang D, Chiu AP, Wan A, Neumaier K, Vlodavsky I, Rodrigues B.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):894-902. doi: 10.1161/ATVBAHA.113.301309. Epub 2013 Mar 7.


Prevalence of infections in residential care homes for the elderly in Hong Kong.

Chen H, Chiu AP, Lam PS, Poon WK, Chow SM, Ng WP, Yung RW.

Hong Kong Med J. 2008 Dec;14(6):444-50.


Cost-effectiveness of oral phenytoin, intravenous phenytoin, and intravenous fosphenytoin in the emergency department.

Rudis MI, Touchette DR, Swadron SP, Chiu AP, Orlinsky M.

Ann Emerg Med. 2004 Mar;43(3):386-97.


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