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The regulatory actions of retinoic acid on M2 polarization of porcine macrophages.

Chen C, Perry TL, Chitko-McKown CG, Smith AD, Cheung L, Beshah E, Urban JF Jr, Dawson HD.

Dev Comp Immunol. 2019 Sep;98:20-33. doi: 10.1016/j.dci.2019.03.020. Epub 2019 Apr 8.


A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin.

Workman AM, Chitko-McKown CG, Smith TPL, Bennett GL, Kalbfleisch TS, Basnayake V, Heaton MP.

F1000Res. 2018 Dec 28;7:1985. doi: 10.12688/f1000research.17187.1. eCollection 2018.


Complete blood count data and leukocyte expression of cytokine genes and cytokine receptor genes associated with bovine respiratory disease in calves.

Lindholm-Perry AK, Kuehn LA, McDaneld TG, Miles JR, Workman AM, Chitko-McKown CG, Keele JW.

BMC Res Notes. 2018 Nov 3;11(1):786. doi: 10.1186/s13104-018-3900-x.


Effect of grinding and long-term storage on the toxicity of white snakeroot (Ageratina altissima) in goats.

Davis TZ, Stegelmeier BL, Lee ST, Green BT, Chitko-McKown CG.

Res Vet Sci. 2018 Jun;118:419-422. doi: 10.1016/j.rvsc.2018.04.006. Epub 2018 Apr 14.


Phenotyping and susceptibility of established porcine cells lines to African Swine Fever Virus infection and viral production.

Sánchez EG, Riera E, Nogal M, Gallardo C, Fernández P, Bello-Morales R, López-Guerrero JA, Chitko-McKown CG, Richt JA, Revilla Y.

Sci Rep. 2017 Sep 4;7(1):10369. doi: 10.1038/s41598-017-09948-x.


Evaluation of the effect of serum antibody abundance against bovine coronavirus on bovine coronavirus shedding and risk of respiratory tract disease in beef calves from birth through the first five weeks in a feedlot.

Workman AM, Kuehn LA, McDaneld TG, Clawson ML, Chitko-McKown CG, Loy JD.

Am J Vet Res. 2017 Sep;78(9):1065-1076. doi: 10.2460/ajvr.78.9.1065.


Timing of transcriptomic and proteomic changes in the bovine placentome after parturition.

McNeel AK, Ondrak JD, Amundson OL, Fountain TH, Wright EC, Whitman KJ, Chitko-McKown CG, Jones SA, Chase CC Jr, Cushman RA.

Theriogenology. 2017 Sep 15;100:1-7. doi: 10.1016/j.theriogenology.2017.05.020. Epub 2017 May 27.


Comparison of the diagnostic performance of bacterial culture of nasopharyngeal swab and bronchoalveolar lavage fluid samples obtained from calves with bovine respiratory disease.

Capik SF, White BJ, Lubbers BV, Apley MD, DeDonder KD, Larson RL, Harhay GP, Chitko-McKown CG, Harhay DM, Kalbfleisch TS, Schuller G, Clawson ML.

Am J Vet Res. 2017 Mar;78(3):350-358. doi: 10.2460/ajvr.78.3.350.


Physiological responses of feedlot heifers provided access to different levels of shade.

Brown-Brandl TM, Chitko-McKown CG, Eigenberg RA, Mayer JJ, Welsh TH, Davis JD, Purswell JL.

Animal. 2017 Aug;11(8):1344-1353. doi: 10.1017/S1751731116002664. Epub 2016 Dec 23.


Genomic signatures of Mannheimia haemolytica that associate with the lungs of cattle with respiratory disease, an integrative conjugative element, and antibiotic resistance genes.

Clawson ML, Murray RW, Sweeney MT, Apley MD, DeDonder KD, Capik SF, Larson RL, Lubbers BV, White BJ, Kalbfleisch TS, Schuller G, Dickey AM, Harhay GP, Heaton MP, Chitko-McKown CG, Brichta-Harhay DM, Bono JL, Smith TP.

BMC Genomics. 2016 Nov 29;17(1):982.


Resolving Bovine viral diarrhea virus subtypes from persistently infected U.S. beef calves with complete genome sequence.

Workman AM, Heaton MP, Harhay GP, Smith TP, Grotelueschen DM, Sjeklocha D, Brodersen B, Petersen JL, Chitko-McKown CG.

J Vet Diagn Invest. 2016 Sep;28(5):519-28. doi: 10.1177/1040638716654943. Epub 2016 Jul 7.


Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle.

Dickey AM, Loy JD, Bono JL, Smith TP, Apley MD, Lubbers BV, DeDonder KD, Capik SF, Larson RL, White BJ, Blom J, Chitko-McKown CG, Clawson ML.

Vet Res. 2016 Feb 13;47:31. doi: 10.1186/s13567-016-0316-2.


Complete Closed Genome Sequences of a Mannheimia haemolytica Serotype A1 Leukotoxin Deletion Mutant and Its Wild-Type Parent Strain.

Heaton MP, Harhay GP, Smith TP, Bono JL, Chitko-McKown CG.

Genome Announc. 2015 May 7;3(3). pii: e00417-15. doi: 10.1128/genomeA.00417-15.


Genetic subgroup of small ruminant lentiviruses that infects sheep homozygous for TMEM154 frameshift deletion mutation A4Δ53.

Clawson ML, Redden R, Schuller G, Heaton MP, Workman A, Chitko-McKown CG, Smith TP, Leymaster KA.

Vet Res. 2015 Mar 5;46:22. doi: 10.1186/s13567-015-0162-7.


Incidence of infection in 39-month-old ewes with TMEM154 diplotypes "1 1," "1 3," and "3 3" after natural exposure to ovine progressive pneumonia virus.

Leymaster KA, Chitko-McKown CG, Heaton MP.

J Anim Sci. 2015 Jan;93(1):41-5. doi: 10.2527/jas.2014-8553.


SNPs for parentage testing and traceability in globally diverse breeds of sheep.

Heaton MP, Leymaster KA, Kalbfleisch TS, Kijas JW, Clarke SM, McEwan J, Maddox JF, Basnayake V, Petrik DT, Simpson B, Smith TP, Chitko-McKown CG; International Sheep Genomics Consortium.

PLoS One. 2014 Apr 16;9(4):e94851. doi: 10.1371/journal.pone.0094851. eCollection 2014.


Complete Closed Genome Sequences of Four Mannheimia varigena Isolates from Cattle with Shipping Fever.

Harhay GP, Murray RW, Lubbers B, Griffin D, Koren S, Phillippy AM, Harhay DM, Bono J, Clawson ML, Heaton MP, Chitko-McKown CG, Smith TP.

Genome Announc. 2014 Feb 13;2(1). pii: e00088-14. doi: 10.1128/genomeA.00088-14.


Complete Closed Genome Sequences of Three Bibersteinia trehalosi Nasopharyngeal Isolates from Cattle with Shipping Fever.

Harhay GP, McVey DS, Koren S, Phillippy AM, Bono J, Harhay DM, Clawson ML, Heaton MP, Chitko-McKown CG, Korlach J, Smith TP.

Genome Announc. 2014 Feb 13;2(1). pii: e00084-14. doi: 10.1128/genomeA.00084-14.


Effects of TMEM154 haplotypes 1 and 3 on susceptibility to ovine progressive pneumonia virus following natural exposure in sheep.

Leymaster KA, Chitko-McKown CG, Clawson ML, Harhay GP, Heaton MP.

J Anim Sci. 2013 Nov;91(11):5114-21. doi: 10.2527/jas.2013-6663. Epub 2013 Aug 29.


Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes.

Sider LH, Heaton MP, Chitko-McKown CG, Harhay GP, Smith TP, Leymaster KA, Laegreid WW, Clawson ML.

Vet Res. 2013 Jul 29;44:64. doi: 10.1186/1297-9716-44-64.


The change in differing leukocyte populations during vaccination to bovine respiratory disease and their correlations with lung scores, health records, and average daily gain.

Leach RJ, Chitko-McKown CG, Bennett GL, Jones SA, Kachman SD, Keele JW, Leymaster KA, Thallman RM, Kuehn LA.

J Anim Sci. 2013 Aug;91(8):3564-73. doi: 10.2527/jas.2012-5911. Epub 2013 Jun 4.


Complete Closed Genome Sequences of Mannheimia haemolytica Serotypes A1 and A6, Isolated from Cattle.

Harhay GP, Koren S, Phillippy AM, McVey DS, Kuszak J, Clawson ML, Harhay DM, Heaton MP, Chitko-McKown CG, Smith TP.

Genome Announc. 2013 May 16;1(3). pii: e00188-13. doi: 10.1128/genomeA.00188-13.


Development and characterization of two porcine monocyte-derived macrophage cell lines.

Chitko-McKown CG, Chapes SK, Miller LC, Riggs PK, Ortega MT, Green BT, McKown RD.

Results Immunol. 2013;3:26-32.


Identification of an ionotropic glutamate receptor AMPA1/GRIA1 polymorphism in crossbred beef cows differing in fertility.

Cushman RA, Miles JR, Rempel LA, McDaneld TG, Kuehn LA, Chitko-McKown CG, Nonneman D, Echternkamp SE.

J Anim Sci. 2013 Jun;91(6):2640-6. doi: 10.2527/jas.2012-5950. Epub 2013 Mar 11.


Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep.

Heaton MP, Kalbfleisch TS, Petrik DT, Simpson B, Kijas JW, Clawson ML, Chitko-McKown CG, Harhay GP, Leymaster KA; International Sheep Genomics Consortium.

PLoS One. 2013;8(2):e55490. doi: 10.1371/journal.pone.0055490. Epub 2013 Feb 11.


Rhodotorula minuta fungemia in a ewe lamb.

Chitko-McKown CG, Leymaster KA, Heaton MP, Griffin DD, Veatch JK, Jones SA, Clawson ML.

Transbound Emerg Dis. 2014 Dec;61(6):e76-8. doi: 10.1111/tbed.12062. Epub 2013 Jan 24.


Reduced lentivirus susceptibility in sheep with TMEM154 mutations.

Heaton MP, Clawson ML, Chitko-Mckown CG, Leymaster KA, Smith TP, Harhay GP, White SN, Herrmann-Hoesing LM, Mousel MR, Lewis GS, Kalbfleisch TS, Keen JE, Laegreid WW.

PLoS Genet. 2012 Jan;8(1):e1002467. doi: 10.1371/journal.pgen.1002467. Epub 2012 Jan 26.


Distribution of Shiga-toxigenic Escherichia coli O157 in the gastrointestinal tract of naturally O157-shedding cattle at necropsy.

Keen JE, Laegreid WW, Chitko-McKown CG, Durso LM, Bono JL.

Appl Environ Microbiol. 2010 Aug;76(15):5278-81. doi: 10.1128/AEM.00400-10. Epub 2010 Jun 11.


Development of fibroblast cell lines from the cow used to sequence the bovine genome.

Chitko-McKown CG, Macneil MD.

Anim Genet. 2010 Aug;41(4):445. doi: 10.1111/j.1365-2052.2009.02013.x. Epub 2009 Dec 16. No abstract available.


The genome sequence of taurine cattle: a window to ruminant biology and evolution.

Bovine Genome Sequencing and Analysis Consortium, Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigó R, Hamernik DL, Kappes SM, Lewin HA, Lynn DJ, Nicholas FW, Reymond A, Rijnkels M, Skow LC, Zdobnov EM, Schook L, Womack J, Alioto T, Antonarakis SE, Astashyn A, Chapple CE, Chen HC, Chrast J, Câmara F, Ermolaeva O, Henrichsen CN, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Kokocinski F, Landrum M, Maglott D, Pruitt K, Sapojnikov V, Searle SM, Solovyev V, Souvorov A, Ucla C, Wyss C, Anzola JM, Gerlach D, Elhaik E, Graur D, Reese JT, Edgar RC, McEwan JC, Payne GM, Raison JM, Junier T, Kriventseva EV, Eyras E, Plass M, Donthu R, Larkin DM, Reecy J, Yang MQ, Chen L, Cheng Z, Chitko-McKown CG, Liu GE, Matukumalli LK, Song J, Zhu B, Bradley DG, Brinkman FS, Lau LP, Whiteside MD, Walker A, Wheeler TT, Casey T, German JB, Lemay DG, Maqbool NJ, Molenaar AJ, Seo S, Stothard P, Baldwin CL, Baxter R, Brinkmeyer-Langford CL, Brown WC, Childers CP, Connelley T, Ellis SA, Fritz K, Glass EJ, Herzig CT, Iivanainen A, Lahmers KK, Bennett AK, Dickens CM, Gilbert JG, Hagen DE, Salih H, Aerts J, Caetano AR, Dalrymple B, Garcia JF, Gill CA, Hiendleder SG, Memili E, Spurlock D, Williams JL, Alexander L, Brownstein MJ, Guan L, Holt RA, Jones SJ, Marra MA, Moore R, Moore SS, Roberts A, Taniguchi M, Waterman RC, Chacko J, Chandrabose MM, Cree A, Dao MD, Dinh HH, Gabisi RA, Hines S, Hume J, Jhangiani SN, Joshi V, Kovar CL, Lewis LR, Liu YS, Lopez J, Morgan MB, Nguyen NB, Okwuonu GO, Ruiz SJ, Santibanez J, Wright RA, Buhay C, Ding Y, Dugan-Rocha S, Herdandez J, Holder M, Sabo A, Egan A, Goodell J, Wilczek-Boney K, Fowler GR, Hitchens ME, Lozado RJ, Moen C, Steffen D, Warren JT, Zhang J, Chiu R, Schein JE, Durbin KJ, Havlak P, Jiang H, Liu Y, Qin X, Ren Y, Shen Y, Song H, Bell SN, Davis C, Johnson AJ, Lee S, Nazareth LV, Patel BM, Pu LL, Vattathil S, Williams RL Jr, Curry S, Hamilton C, Sodergren E, Wheeler DA, Barris W, Bennett GL, Eggen A, Green RD, Harhay GP, Hobbs M, Jann O, Keele JW, Kent MP, Lien S, McKay SD, McWilliam S, Ratnakumar A, Schnabel RD, Smith T, Snelling WM, Sonstegard TS, Stone RT, Sugimoto Y, Takasuga A, Taylor JF, Van Tassell CP, Macneil MD, Abatepaulo AR, Abbey CA, Ahola V, Almeida IG, Amadio AF, Anatriello E, Bahadue SM, Biase FH, Boldt CR, Carroll JA, Carvalho WA, Cervelatti EP, Chacko E, Chapin JE, Cheng Y, Choi J, Colley AJ, de Campos TA, De Donato M, Santos IK, de Oliveira CJ, Deobald H, Devinoy E, Donohue KE, Dovc P, Eberlein A, Fitzsimmons CJ, Franzin AM, Garcia GR, Genini S, Gladney CJ, Grant JR, Greaser ML, Green JA, Hadsell DL, Hakimov HA, Halgren R, Harrow JL, Hart EA, Hastings N, Hernandez M, Hu ZL, Ingham A, Iso-Touru T, Jamis C, Jensen K, Kapetis D, Kerr T, Khalil SS, Khatib H, Kolbehdari D, Kumar CG, Kumar D, Leach R, Lee JC, Li C, Logan KM, Malinverni R, Marques E, Martin WF, Martins NF, Maruyama SR, Mazza R, McLean KL, Medrano JF, Moreno BT, Moré DD, Muntean CT, Nandakumar HP, Nogueira MF, Olsaker I, Pant SD, Panzitta F, Pastor RC, Poli MA, Poslusny N, Rachagani S, Ranganathan S, Razpet A, Riggs PK, Rincon G, Rodriguez-Osorio N, Rodriguez-Zas SL, Romero NE, Rosenwald A, Sando L, Schmutz SM, Shen L, Sherman L, Southey BR, Lutzow YS, Sweedler JV, Tammen I, Telugu BP, Urbanski JM, Utsunomiya YT, Verschoor CP, Waardenberg AJ, Wang Z, Ward R, Weikard R, Welsh TH Jr, White SN, Wilming LG, Wunderlich KR, Yang J, Zhao FQ.

Science. 2009 Apr 24;324(5926):522-8. doi: 10.1126/science.1169588.


Development of cell lines from the sheep used to construct the CHORI-243 Ovine BAC library.

Chitko-McKown CG, Leonard JC, Moscatello D, Miller LC, Freking BA.

Anim Biotechnol. 2008;19(2):84-8. doi: 10.1080/10495390801967684.


Use of bovine single nucleotide polymorphism markers to verify sample tracking in beef processing.

Heaton MP, Keen JE, Clawson ML, Harhay GP, Bauer N, Shultz C, Green BT, Durso L, Chitko-McKown CG, Laegreid WW.

J Am Vet Med Assoc. 2005 Apr 15;226(8):1311-4.


Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells.

Miller LC, Laegreid WW, Bono JL, Chitko-McKown CG, Fox JM.

Arch Virol. 2004 Dec;149(12):2453-63. Epub 2004 Aug 27.


Gene expression profiling of bovine macrophages in response to Escherichia coli O157:H7 lipopolysaccharide.

Chitko-McKown CG, Fox JM, Miller LC, Heaton MP, Bono JL, Keen JE, Grosse WM, Laegreid WW.

Dev Comp Immunol. 2004 May 17;28(6):635-45.


Male-specific SRY and ZFY haplotypes in US beef cattle.

Clawson ML, Heaton MP, Fox JM, Chitko-McKown CG, Smith TP, Laegreid WW.

Anim Genet. 2004 Jun;35(3):246-9. No abstract available.


Beta-2-microglobulin haplotypes in U.S. beef cattle and association with failure of passive transfer in newborn calves.

Clawson ML, Heaton MP, Chitko-McKown CG, Fox JM, Smith TP, Snelling WM, Keele JW, Laegreid WW.

Mamm Genome. 2004 Mar;15(3):227-36.


Evaluation of a real-time PCR kit for detecting Escherichia coli O157 in bovine fecal samples.

Bono JL, Keen JE, Miller LC, Fox JM, Chitko-McKown CG, Heaton MP, Laegreid WW.

Appl Environ Microbiol. 2004 Mar;70(3):1855-7.


Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer.

Heaton MP, Leymaster KA, Freking BA, Hawk DA, Smith TP, Keele JW, Snelling WM, Fox JM, Chitko-McKown CG, Laegreid WW.

Mamm Genome. 2003 Nov;14(11):765-77.


Association of bovine neonatal Fc receptor alpha-chain gene (FCGRT) haplotypes with serum IgG concentration in newborn calves.

Laegreid WW, Heaton MP, Keen JE, Grosse WM, Chitko-McKown CG, Smith TP, Keele JW, Bennett GL, Besser TE.

Mamm Genome. 2002 Dec;13(12):704-10.


Selection and use of SNP markers for animal identification and paternity analysis in U.S. beef cattle.

Heaton MP, Harhay GP, Bennett GL, Stone RT, Grosse WM, Casas E, Keele JW, Smith TP, Chitko-McKown CG, Laegreid WW.

Mamm Genome. 2002 May;13(5):272-81.


Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle.

Smith TP, Grosse WM, Freking BA, Roberts AJ, Stone RT, Casas E, Wray JE, White J, Cho J, Fahrenkrug SC, Bennett GL, Heaton MP, Laegreid WW, Rohrer GA, Chitko-McKown CG, Pertea G, Holt I, Karamycheva S, Liang F, Quackenbush J, Keele JW.

Genome Res. 2001 Apr;11(4):626-30.


Estimation of DNA sequence diversity in bovine cytokine genes.

Heaton MP, Grosse WM, Kappes SM, Keele JW, Chitko-McKown CG, Cundiff LV, Braun A, Little DP, Laegreid WW.

Mamm Genome. 2001 Jan;12(1):32-7.


Single nucleotide polymorphism (SNP) discovery and linkage mapping of bovine cytokine genes.

Grosse WM, Kappes SM, Laegreid WW, Keele JW, Chitko-McKown CG, Heaton MP.

Mamm Genome. 1999 Nov;10(11):1062-9.


Quantitative and qualitative signals determine T-cell cycle entry and progression.

Modiano JF, Mayor J, Ball C, Chitko-McKown CG, Sakata N, Domenico-Hahn J, Lucas JJ, Gelfand EW.

Cell Immunol. 1999 Oct 10;197(1):19-29.


Immunization with Babesia bigemina rhoptry-associated protein 1 induces a type 1 cytokine response.

Ruef BJ, Tuo W, Rodriguez SD, Roussel AJ, Chitko-McKown CG, Palmer GH, McElwain TF, Canals A, Zarlenga DS, Gasbarre LC, Brown WC.

J Interferon Cytokine Res. 1997 Jan;17(1):45-54.


Babesia bovis rhoptry-associated protein 1 is immunodominant for T helper cells of immune cattle and contains T-cell epitopes conserved among geographically distant B. bovis strains.

Brown WC, McElwain TF, Ruef BJ, Suarez CE, Shkap V, Chitko-McKown CG, Tuo W, Rice-Ficht AC, Palmer GH.

Infect Immun. 1996 Aug;64(8):3341-50.


Characterization of helper T cell responses against rhoptry-associated protein 1 (RAP-1) of babesial parasites.

Brown WC, Rodriguez SD, Hotzel I, Ruef BJ, Chitko-McKown CG, McElwain TF, Palmer GH.

Ann N Y Acad Sci. 1996 Jul 23;791:128-35. No abstract available.


Influence of recombinant bovine interleukin-1 beta and interleukin-2 in pigs vaccinated and challenged with Streptococcus suis.

Blecha F, Reddy DN, Chitko-McKown CG, McVey DS, Chengappa MM, Goodband RD, Nelssen JL.

Vet Immunol Immunopathol. 1995 Feb;44(3-4):329-46.


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