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Items: 50

1.

Upregulation of smooth muscle Rho-kinase protein expression in human asthma.

Wang L, Chitano P, Paré PD, Seow CY.

Eur Respir J. 2020 Mar 5;55(3). pii: 1901785. doi: 10.1183/13993003.01785-2019. Print 2020 Mar. No abstract available.

PMID:
31727693
2.

The Huxley crossbridge model as the basic mechanism for airway smooth muscle contraction.

Luo L, Wang L, Paré PD, Seow CY, Chitano P.

Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L235-L246. doi: 10.1152/ajplung.00051.2019. Epub 2019 May 22.

PMID:
31116578
3.

Smooth muscle function and myosin polymerization.

Chitano P, Wang L, Tin GYY, Ikebe M, Paré PD, Seow CY.

J Cell Sci. 2017 Aug 1;130(15):2468-2480. doi: 10.1242/jcs.202812. Epub 2017 Jun 8.

4.

Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness.

Chitano P, Wang L, Degan S, Worthington CL, Pozzato V, Hussaini SH, Turner WC, Dorscheid DR, Murphy TM.

Physiol Rep. 2014 Dec 11;2(12). pii: e12241. doi: 10.14814/phy2.12241. Print 2014 Dec 1.

5.

Models to understand contractile function in the airways.

Chitano P.

Pulm Pharmacol Ther. 2011 Oct;24(5):444-51. doi: 10.1016/j.pupt.2011.04.028. Epub 2011 Apr 14. Review.

PMID:
21511049
6.

Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release.

Wang L, Pozzato V, Turato G, Madamanchi A, Murphy TM, Chitano P.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L964-73. doi: 10.1152/ajplung.00401.2007. Epub 2008 Mar 7.

7.

Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase.

Chitano P, Wang L, Mason SN, Auten RL, Potts EN, Foster WM, Sturrock A, Kennedy TP, Hoidal JR, Murphy TM.

Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L139-48. Epub 2007 Nov 9. Retraction in: Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L854.

8.

Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs.

Chitano P, Wang L, Murphy TM.

Can J Physiol Pharmacol. 2007 Jul;85(7):715-26. Review.

9.

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L.

Eur Respir J. 2007 May;29(5):834-60. Review.

10.

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

Sturrock A, Huecksteadt TP, Norman K, Sanders K, Murphy TM, Chitano P, Wilson K, Hoidal JR, Kennedy TP.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1543-55. Epub 2007 Mar 16.

11.

Mechanisms of airway smooth muscle relaxation during maturation.

Chitano P, Wang L, Murphy TM.

Can J Physiol Pharmacol. 2005 Oct;83(10):833-40. Review.

PMID:
16333354
12.

A maturational model for the study of airway smooth muscle adaptation to mechanical oscillation.

Wang L, Chitano P, Murphy TM.

Can J Physiol Pharmacol. 2005 Oct;83(10):817-24. Review.

PMID:
16333352
13.

S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery.

Nozik-Grayck E, Whalen EJ, Stamler JS, McMahon TJ, Chitano P, Piantadosi CA.

Am J Physiol Lung Cell Mol Physiol. 2006 Jan;290(1):L136-43. Epub 2005 Aug 26.

14.

Maturation of guinea pig tracheal strip stiffness.

Wang L, Chitano P, Murphy TM.

Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L902-8. Epub 2005 Jun 10.

15.

Length oscillation induces force potentiation in infant guinea pig airway smooth muscle.

Wang L, Chitano P, Murphy TM.

Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L909-15. Epub 2005 Jun 3.

16.

Ontogenesis of myosin light chain phosphorylation in guinea pig tracheal smooth muscle.

Chitano P, Worthington CL, Jenkin JA, Stephens NL, Gyapong S, Wang L, Murphy TM.

Pediatr Pulmonol. 2005 Feb;39(2):108-16.

17.

On the terminology for describing the length-force relationship and its changes in airway smooth muscle.

Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L.

J Appl Physiol (1985). 2004 Dec;97(6):2029-34. Review.

18.

Ontogenesis of myosin light chain kinase mRNA and protein content in guinea pig tracheal smooth muscle.

Chitano P, Voynow JA, Pozzato V, Cantillana V, Burch LH, Wang L, Murphy TM.

Pediatr Pulmonol. 2004 Dec;38(6):456-64.

19.

Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans.

Luberto C, Martinez-Mariño B, Taraskiewicz D, Bolaños B, Chitano P, Toffaletti DL, Cox GM, Perfect JR, Hannun YA, Balish E, Del Poeta M.

J Clin Invest. 2003 Oct;112(7):1080-94.

20.

Maturational changes in airway smooth muscle shortening and relaxation. Implications for asthma.

Chitano P, Murphy TM.

Respir Physiol Neurobiol. 2003 Sep 16;137(2-3):347-59.

PMID:
14516737
21.

Reducing agents inhibit the contractile response of isolated guinea-pig main bronchi.

Casoni GL, Chitano P, Pinamonti S, Chicca M, Ciaccia A, Fabbri L, Papi A.

Clin Exp Allergy. 2003 Jul;33(7):999-1004.

PMID:
12859459
22.

Growing up and advancing in airway smooth muscle research.

Chitano P, Halayko AJ, Murphy TM, Stewart AG.

Trends Pharmacol Sci. 2002 Oct;23(10):450-1. No abstract available.

PMID:
12368062
23.

Relaxation of guinea pig trachealis during electrical field stimulation increases with age.

Chitano P, Cox CM, Murphy TM.

J Appl Physiol (1985). 2002 May;92(5):1835-42.

24.

NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle.

Brar SS, Kennedy TP, Sturrock AB, Huecksteadt TP, Quinn MT, Murphy TM, Chitano P, Hoidal JR.

Am J Physiol Lung Cell Mol Physiol. 2002 Apr;282(4):L782-95.

25.

Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi.

Boschetto P, Jovine L, Chitano P, De Marzo N, Plebani M, Faggian D, Fabbri LM, Mapp CE.

Respir Med. 2001 May;95(5):357-62.

26.

Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis.

Chitano P, Wang J, Cox CM, Stephens NL, Murphy TM.

J Appl Physiol (1985). 2000 Apr;88(4):1338-45.

27.

Bronchopulmonary inflammation and airway smooth muscle hyperresponsiveness induced by nitrogen dioxide in guinea pigs.

Papi A, Amadesi S, Chitano P, Boschetto P, Ciaccia A, Geppetti P, Fabbri LM, Mapp CE.

Eur J Pharmacol. 1999 Jun 18;374(2):241-7.

PMID:
10422765
28.

Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle.

Brar SS, Kennedy TP, Whorton AR, Murphy TM, Chitano P, Hoidal JR.

J Biol Chem. 1999 Jul 9;274(28):20017-26.

29.

Immunization and challenge with toluene diisocyanate decrease tachykinin and calcitonin gene-related peptide immunoreactivity in guinea pig central airways.

Mapp CE, Lucchini RE, Miotto D, Chitano P, Jovine L, Saetta M, Maestrelli P, Springall DR, Polak J, Fabbri LM.

Am J Respir Crit Care Med. 1998 Jul;158(1):263-9.

PMID:
9655739
30.

Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation.

Dashtaki R, Whorton AR, Murphy TM, Chitano P, Reed W, Kennedy TP.

J Pharmacol Exp Ther. 1998 May;285(2):876-83.

PMID:
9580639
31.

Isotonic smooth muscle response in human bronchi exposed in vitro to nitrogen dioxide.

Chitano P, Lucchini RE, Calabrò F, Saetta M, Maestrelli P, Fabbri LM, Mapp CE.

Eur Respir J. 1996 Nov;9(11):2294-7.

32.
33.

Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate.

Mapp CE, Lapa e Silva JR, Lucchini RE, Chitano P, Rado V, Saetta M, Pretolani M, Karol MH, Maestrelli P, Fabbri LM.

Am J Respir Crit Care Med. 1996 Jul;154(1):201-8.

PMID:
8680681
34.

Effect of subchronic in vivo exposure to nitrogen dioxide on lung tissue inflammation, airway microvascular leakage, and in vitro bronchial muscle responsiveness in rats.

Chitano P, Rado V, Di Stefano A, Papi A, Boniotti A, Zancuoghi G, Boschetto P, Romano M, Salmona M, Ciaccia A, Fabbri LM, Mapp CE.

Occup Environ Med. 1996 Jun;53(6):379-86.

35.

Increased response to antigen and histamine release in smaller sensitized canine bronchi.

Chitano P, Sigurdsson SB, Stephens AM, Becker AB, Kepron W, Stephens NL.

Respir Physiol. 1996 Mar;103(3):253-61.

PMID:
8738901
36.

The Schultz-Dale response of sensitized canine bronchial smooth muscle.

Sigurdsson SB, Chitano P, Stephens NL.

Respir Physiol. 1995 Oct;102(1):79-87.

PMID:
8610211
37.

Effect of oxidant air pollutants on the respiratory system: insights from experimental animal research.

Chitano P, Hosselet JJ, Mapp CE, Fabbri LM.

Eur Respir J. 1995 Aug;8(8):1357-71. Review.

38.

In-vitro exposure of guinea pig main bronchi to 2.5 ppm of nitrogen dioxide does not alter airway smooth muscle response.

Chitano P, Lucchini RE, Coser E, Papi A, Saetta M, Maestrelli P, Ciaccia A, Fabbri LM, Mapp CE.

Respir Med. 1995 May;89(5):323-8.

39.

In vitro exposure to nitrogen dioxide (NO2) does not alter bronchial smooth muscle responsiveness in ovalbumin-sensitized guinea-pigs.

Chitano P, Coser E, Lucchini RE, Papi A, Saetta M, Maestrelli P, Faggian D, Plebani M, Ciaccia A, Fabbri LM, et al.

Pulm Pharmacol. 1994 Aug;7(4):251-7.

PMID:
7620240
40.

The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro.

Chitano P, Di Blasi P, Lucchini RE, Calabrò F, Saetta M, Maestrelli P, Fabbri LM, Mapp CE.

Eur J Pharmacol. 1994 Apr 4;270(2-3):167-73.

PMID:
7518777
41.

Mechanisms and pathology of occupational asthma.

Mapp CE, Saetta M, Maestrelli P, Di Stefano A, Chitano P, Boschetto P, Ciaccia A, Fabbri LM.

Eur Respir J. 1994 Mar;7(3):544-54. Review. Erratum in: Eur Respir J 1995 Apr;8(4):667.

42.

Relevance of classification by size to topographical differences in bronchial smooth muscle response.

Chitano P, Sigurdsson SB, Halayko AJ, Stephens NL.

J Appl Physiol (1985). 1993 Nov;75(5):2013-21.

PMID:
8307854
43.

The effect of compound 48/80 on contractions induced by toluene diisocyanate in isolated guinea-pig bronchus.

Mapp CE, Boniotti A, Papi A, Chitano P, Coser E, Di Stefano A, Saetta M, Ciaccia A, Fabbri LM.

Eur J Pharmacol. 1993 Jun 1;248(1):67-73.

PMID:
7687959
44.

The products of the reaction between toluene diisocyanate and water contract isolated guinea pig bronchi.

Mapp CE, Boniotti A, Papi A, Chitano P, Fabbri LM, Ciaccia A.

Eur J Pharmacol. 1992 Sep 1;228(2-3):103-6.

PMID:
1332877
45.

The effect of phosphoramidon and epithelium removal on toluene diisocyanate-induced contractions in guinea-pig bronchi.

Mapp CE, Boniotti A, Papi A, Chitano P, Saetta M, Di Stefano A, Ciaccia A, Fabbri LM.

Eur Respir J. 1992 Mar;5(3):331-3.

PMID:
1315295
46.

Bronchial smooth muscle responses evoked by toluene diisocyanate are inhibited by ruthenium red and by indomethacin.

Mapp CE, Boniotti A, Graf PD, Chitano P, Fabbri LM, Nadel JA.

Eur J Pharmacol. 1991 Jul 23;200(1):73-6.

PMID:
1722756
47.

Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder.

Mapp CE, Chitano P, Fabbri LM, Patacchini R, Maggi CA.

Br J Pharmacol. 1990 Aug;100(4):886-8.

48.

Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents.

Mapp CE, Chitano P, Fabbri LM, Patacchini R, Santicioli P, Geppetti P, Maggi CA.

Eur J Pharmacol. 1990 May 3;180(1):113-8.

PMID:
2163862
49.

Response to acetylcholine and myosin content of isolated canine airways.

Mapp CE, Chitano P, De Marzo N, Di Blasi P, Saetta M, Di Stefano A, Bosco VM, Allegra L, Fabbri LM.

J Appl Physiol (1985). 1989 Oct;67(4):1331-5.

PMID:
2793732
50.

Ambroxol inhibits airway hyperresponsiveness induced by ozone in dogs.

Chitano P, Di Stefano A, Finotto S, Zavattini G, Maestrelli P, Mapp C, Fabbri LM, Allegra L.

Respiration. 1989;55 Suppl 1:74-8.

PMID:
2813981

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