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Discerning the Age-Related Heterogeneity in Heart Failure With Preserved Ejection Fraction.

Chirinos JA.

J Am Coll Cardiol. 2019 Aug 6;74(5):613-616. doi: 10.1016/j.jacc.2019.06.008. No abstract available.


Feasibility and agreement of a novel combined echocardiographic method to measure global longitudinal strain and strain rate compared to speckle tracking and tissue Doppler imaging.

Van Daele CM, Chirinos JA, De Buyzere ML, Gillebert TC, Rietzschel ER.

Acta Cardiol. 2019 May 9:1-9. doi: 10.1080/00015385.2019.1565661. [Epub ahead of print]


Soluble FMS-Like Tyrosine Kinase-1 Is a Circulating Biomarker Associated With Calcific Aortic Stenosis.

Small AM, Kiss DH, Anwaruddin S, Giri J, Han Y, Zhao L, Salvador L, Cvijic ME, Li Z, Chirinos JA, Damrauer SM, Rader DJ.

J Am Coll Cardiol. 2019 Mar 26;73(11):1364-1365. doi: 10.1016/j.jacc.2019.01.020. No abstract available.


Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension.

Bhattacharya PT, Troutman GS, Mao F, Fox AL, Tanna MS, Zamani P, Grandin EW, Menachem JN, Birati EY, Chirinos JA, Mazimba S, Smith KA, Kawut SM, Forfia PR, Vaidya A, Mazurek JA.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019841978. doi: 10.1177/2045894019841978.


The role of ventricular-arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association.

Ikonomidis I, Aboyans V, Blacher J, Brodmann M, Brutsaert DL, Chirinos JA, De Carlo M, Delgado V, Lancellotti P, Lekakis J, Mohty D, Nihoyannopoulos P, Parissis J, Rizzoni D, Ruschitzka F, Seferovic P, Stabile E, Tousoulis D, Vinereanu D, Vlachopoulos C, Vlastos D, Xaplanteris P, Zimlichman R, Metra M.

Eur J Heart Fail. 2019 Apr;21(4):402-424. doi: 10.1002/ejhf.1436. Epub 2019 Mar 12.


Mitochondrial Dysfunction in Heart Failure With Preserved Ejection Fraction.

Kumar AA, Kelly DP, Chirinos JA.

Circulation. 2019 Mar 12;139(11):1435-1450. doi: 10.1161/CIRCULATIONAHA.118.036259.


The Authors Reply.

Chirinos JA, Akers SR, Ansari B, Jain S.

JACC Cardiovasc Imaging. 2019 Mar;12(3):570-571. doi: 10.1016/j.jcmg.2019.01.008. No abstract available.


Magnetic Resonance Imaging of Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction: Ready for Prime Time?

Chirinos JA.

JACC Cardiovasc Imaging. 2019 Feb 11. pii: S1936-878X(19)30060-9. doi: 10.1016/j.jcmg.2018.12.019. [Epub ahead of print] No abstract available.


Impact of Diabetes Mellitus on Ventricular Structure, Arterial Stiffness, and Pulsatile Hemodynamics in Heart Failure With Preserved Ejection Fraction.

Chirinos JA, Bhattacharya P, Kumar A, Proto E, Konda P, Segers P, Akers SR, Townsend RR, Zamani P.

J Am Heart Assoc. 2019 Feb 19;8(4):e011457. doi: 10.1161/JAHA.118.011457.


Axial Muscle Size as a Strong Predictor of Death in Subjects With and Without Heart Failure.

Kumar A, Ansari BA, Kim J, Suri A, Gaddam S, Yenigalla S, Vanjarapu JM, Selvaraj S, Tamvada D, Lee J, Akers SR, Chirinos JA.

J Am Heart Assoc. 2019 Feb 19;8(4):e010554. doi: 10.1161/JAHA.118.010554.


Usefulness of Left Ventricular Strain by Cardiac Magnetic Resonance Feature-Tracking to Predict Cardiovascular Events in Patients With and Without Heart Failure.

Sardana M, Konda P, Hashmath Z, Oldland G, Gaddam S, Miller R, Satija V, Ansari B, Lee J, Mustafa A, Akers SR, Chirinos JA.

Am J Cardiol. 2019 Apr 15;123(8):1301-1308. doi: 10.1016/j.amjcard.2019.01.025. Epub 2019 Jan 25.


Arterial Properties as Determinants of Left Ventricular Mass and Fibrosis in Severe Aortic Stenosis: Findings From ACRIN PA 4008.

Chirinos JA, Akers SR, Schelbert E, Snyder BS, Witschey WR, Jacob RM, Jamis-Dow C, Ansari B, Lee J, Segers P, Schnall M, Cavalcante JL.

J Am Heart Assoc. 2019 Jan 8;8(1):e03742. doi: 10.1161/JAHA.118.010271.


Vitamin K Status, Warfarin Use, and Arterial Stiffness in Heart Failure.

Hashmath Z, Lee J, Gaddam S, Ansari B, Oldland G, Javaid K, Mustafa A, Vasim I, Akers S, Chirinos JA.

Hypertension. 2019 Feb;73(2):364-370. doi: 10.1161/HYPERTENSIONAHA.118.12157.


Effect of Obesity on Left Atrial Strain in Persons Aged 35-55 Years (The Asklepios Study).

Chirinos JA, Sardana M, Satija V, Gillebert TC, De Buyzere ML, Chahwala J, De Bacquer D, Segers P, Rietzschel ER; Asklepios investigators.

Am J Cardiol. 2019 Mar 1;123(5):854-861. doi: 10.1016/j.amjcard.2018.11.035. Epub 2018 Dec 4.


Left Atrial Phasic Function by Cardiac Magnetic Resonance Feature Tracking Is a Strong Predictor of Incident Cardiovascular Events.

Chirinos JA, Sardana M, Ansari B, Satija V, Kuriakose D, Edelstein I, Oldland G, Miller R, Gaddam S, Lee J, Suri A, Akers SR.

Circ Cardiovasc Imaging. 2018 Dec;11(12):e007512. doi: 10.1161/CIRCIMAGING.117.007512.


Cardio-ankle vascular index and cardiovascular disease: Systematic review and meta-analysis of prospective and cross-sectional studies.

Matsushita K, Ding N, Kim ED, Budoff M, Chirinos JA, Fernhall B, Hamburg NM, Kario K, Miyoshi T, Tanaka H, Townsend R.

J Clin Hypertens (Greenwich). 2019 Jan;21(1):16-24. doi: 10.1111/jch.13425. Epub 2018 Nov 19. Review.


Hemodynamic Patterns Identified by Impedance Cardiography Predict Mortality in the General Population: The PREVENCION Study.

Medina-Lezama J, Narvaez-Guerra O, Herrera-Enriquez K, Morey-Vargas OL, Bolaños-Salazar JF, Abugattas JP, Zea-Diaz H, Chirinos-Revilla JL, Fernandez-Sivincha JG, Delgado-Lazo V, Chirinos DA, Townsend RR, Chirinos JA.

J Am Heart Assoc. 2018 Sep 18;7(18):e009259. doi: 10.1161/JAHA.118.009259.


Systemic Hypertension at High Altitude.

Narvaez-Guerra O, Herrera-Enriquez K, Medina-Lezama J, Chirinos JA.

Hypertension. 2018 Sep;72(3):567-578. doi: 10.1161/HYPERTENSIONAHA.118.11140. Review. No abstract available.


Physical Activity Following Positive Airway Pressure Treatment in Adults With and Without Obesity and With Moderate-Severe Obstructive Sleep Apnea.

Feng Y, Maislin D, Keenan BT, Gislason T, Arnardottir ES, Benediktsdottir B, Chirinos JA, Townsend RR, Staley B, Pack FM, Sifferman A, Pack AI, Kuna ST.

J Clin Sleep Med. 2018 Oct 15;14(10):1705-1715. doi: 10.5664/jcsm.7378.


Right Atrial Phasic Function in Heart Failure With Preserved and Reduced Ejection Fraction.

Jain S, Kuriakose D, Edelstein I, Ansari B, Oldland G, Gaddam S, Javaid K, Manaktala P, Lee J, Miller R, Akers SR, Chirinos JA.

JACC Cardiovasc Imaging. 2019 Aug;12(8 Pt 1):1460-1470. doi: 10.1016/j.jcmg.2018.08.020. Epub 2018 Oct 17.


[Safety of gastroenterologist-directed propofol administration for endoscopic procedures: 10-year experience in a private clinic in Lima, Peru].

Espinoza-Ríos J, Chirinos JA, Tagle Arróspide M.

Rev Gastroenterol Peru. 2018 Apr-Jun;38(2):157-163. Spanish.


Aldosterone, inactive matrix gla-protein, and large artery stiffness in hypertension.

Chirinos JA, Sardana M, Syed AA, Koppula MR, Varakantam S, Vasim I, Oldland HG, Phan TS, Drummen NEA, Vermeer C, Townsend RR, Akers SR, Wei W, Lakatta EG, Fedorova OV.

J Am Soc Hypertens. 2018 Sep;12(9):681-689. doi: 10.1016/j.jash.2018.06.018. Epub 2018 Jun 30.


Poor Glycemic Control Is Associated With Increased Extracellular Volume Fraction in Diabetes.

Al-Badri A, Hashmath Z, Oldland GH, Miller R, Javaid K, Syed AA, Ansari B, Gaddam S, Witschey WR, Akers SR, Chirinos JA.

Diabetes Care. 2018 Sep;41(9):2019-2025. doi: 10.2337/dc18-0324. Epub 2018 Jul 12.


Embracing the Long Road to Precision Medicine.

Chirinos JA, Lanfear DE.

Circ Heart Fail. 2018 Jul;11(7):e005089. doi: 10.1161/CIRCHEARTFAILURE.118.005089. No abstract available.


Association of arginine vasopressin with low atrial natriuretic peptide levels, left ventricular remodelling, and outcomes in adults with and without heart failure.

Chirinos JA, Sardana M, Oldland G, Ansari B, Lee J, Hussain A, Mustafa A, Akers SR, Wei W, Lakatta EG, Fedorova OV.

ESC Heart Fail. 2018 Oct;5(5):911-919. doi: 10.1002/ehf2.12319. Epub 2018 Jul 3.


"Sleep disordered breathing and ECG R-wave to radial artery pulse delay, The Multi-Ethnic Study of Atherosclerosis".

Kwon Y, Jacobs DR Jr, Lutsey PL, Brumback L, Chirinos JA, Mariani S, Redline S, Duprez DA.

Sleep Med. 2018 Aug;48:172-179. doi: 10.1016/j.sleep.2018.05.005. Epub 2018 May 21.


Pulsatile arterial haemodynamics in heart failure.

Weber T, Chirinos JA.

Eur Heart J. 2018 Nov 14;39(43):3847-3854. doi: 10.1093/eurheartj/ehy346.


Circulating Dephospho-Uncarboxylated Matrix Gla-Protein Is Associated With Kidney Dysfunction and Arterial Stiffness.

Puzantian H, Akers SR, Oldland G, Javaid K, Miller R, Ge Y, Ansari B, Lee J, Suri A, Hasmath Z, Townsend R, Chirinos JA.

Am J Hypertens. 2018 Aug 3;31(9):988-994. doi: 10.1093/ajh/hpy079.


Association of Pulse Wave Velocity With Chronic Kidney Disease Progression and Mortality: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort).

Townsend RR, Anderson AH, Chirinos JA, Feldman HI, Grunwald JE, Nessel L, Roy J, Weir MR, Wright JT Jr, Bansal N, Hsu CY; CRIC Study Investigators.

Hypertension. 2018 Jun;71(6):1101-1107. doi: 10.1161/HYPERTENSIONAHA.117.10648. Epub 2018 Apr 30.


When the VEST Does Not Fit: Representations of Trial Results Deviating From Rigorous Data Interpretation.

Allen LA, Adler ED, Bayés-Genis A, Brisco-Bacik MA, Chirinos JA, Claggett B, Cook JL, Fang JC, Gustafsson F, Ho CY, Kapur NK, Klewer SE, Kociol RD, Lanfear DE, Vardeny O, Sweitzer NK.

Circ Heart Fail. 2018 Apr;11(4):e005116. doi: 10.1161/CIRCHEARTFAILURE.118.005116. No abstract available.


Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma.

Catino AB, Hubbard RA, Chirinos JA, Townsend R, Keefe S, Haas NB, Puzanov I, Fang JC, Agarwal N, Hyman D, Smith AM, Gordon M, Plappert T, Englefield V, Narayan V, Ewer S, ElAmm C, Lenihan D, Ky B.

Circ Heart Fail. 2018 Mar;11(3):e004408. doi: 10.1161/CIRCHEARTFAILURE.117.004408.


A Unified Mechanism for the Water Hammer Pulse and Pulsus Bisferiens in Severe Aortic Regurgitation: Insights from Wave Intensity Analysis.

Chirinos JA, Akers SR, Vierendeels JA, Segers P.

Artery Res. 2018 Mar;21:9-12. doi: 10.1016/j.artres.2017.12.002. Epub 2017 Dec 21. No abstract available.


Effect of organic and inorganic nitrates on cerebrovascular pulsatile power transmission in patients with heart failure and preserved ejection fraction.

Londono-Hoyos F, Zamani P, Beraun M, Vasim I, Segers P, Chirinos JA.

Physiol Meas. 2018 Apr 20;39(4):044001. doi: 10.1088/1361-6579/aab2ef.


Coronary artery calcium before and after hospitalization with pneumonia: The MESA study.

Corrales-Medina VF, Dwivedi G, Taljaard M, Petrcich W, Lima JA, Yende S, Kronmal RA, Chirinos JA.

PLoS One. 2018 Feb 8;13(2):e0191750. doi: 10.1371/journal.pone.0191750. eCollection 2018.


The Nitrate-Nitrite-NO Pathway as a Novel Therapeutic Target in Heart Failure with Reduced Ejection Fraction.

Chirinos JA.

J Card Fail. 2018 Feb;24(2):74-77. doi: 10.1016/j.cardfail.2017.12.001. Epub 2017 Dec 13. No abstract available.


Effect of CPAP, Weight Loss, or CPAP Plus Weight Loss on Central Hemodynamics and Arterial Stiffness.

Jain S, Gurubhagavatula I, Townsend R, Kuna ST, Teff K, Wadden TA, Chittams J, Hanlon AL, Maislin G, Saif H, Broderick P, Ahmad Z, Pack AI, Chirinos JA.

Hypertension. 2017 Dec;70(6):1283-1290. doi: 10.1161/HYPERTENSIONAHA.117.09392. Epub 2017 Oct 16.


Carotid Artery Wall Thickness in Obese and Nonobese Adults With Obstructive Sleep Apnea Before and Following Positive Airway Pressure Treatment.

Kim J, Mohler ER 3rd, Keenan BT, Maislin D, Arnardottir ES, Gislason T, Benediktsdottir B, Gudmundsdottir S, Sifferman A, Staley B, Pack FM, Maislin G, Chirinos JA, Townsend RR, Pack AI, Kuna ST.

Sleep. 2017 Sep 1;40(9). doi: 10.1093/sleep/zsx126.


Central systolic blood pressure and aortic stiffness response to dietary sodium in young and middle-aged adults.

Muth BJ, Brian MS, Chirinos JA, Lennon SL, Farquhar WB, Edwards DG.

J Am Soc Hypertens. 2017 Oct;11(10):627-634. doi: 10.1016/j.jash.2017.07.010. Epub 2017 Jul 28.


Assessment of methodologies to calculate intraventricular pressure differences in computational models and patients.

Londono-Hoyos FJ, Swillens A, Van Cauwenberge J, Meyers B, Koppula MR, Vlachos P, Chirinos JA, Segers P.

Med Biol Eng Comput. 2018 Mar;56(3):469-481. doi: 10.1007/s11517-017-1704-0. Epub 2017 Aug 16.


Right Heart Function During and After Community-Acquired Pneumonia in Adults.

Boczar KE, Corrales-Medina VF, Burwash IG, Chirinos JA, Dwivedi G.

Heart Lung Circ. 2018 Jun;27(6):745-747. doi: 10.1016/j.hlc.2017.06.730. Epub 2017 Jul 27.


Ventricular-Arterial Coupling in Chronic Heart Failure.

Chirinos JA, Sweitzer N.

Card Fail Rev. 2017 Apr;3(1):12-18. doi: 10.15420/cfr.2017:4:2.


Depressive symptoms in patients with obstructive sleep apnea: biological mechanistic pathways.

Chirinos DA, Gurubhagavatula I, Broderick P, Chirinos JA, Teff K, Wadden T, Maislin G, Saif H, Chittams J, Cassidy C, Hanlon AL, Pack AI.

J Behav Med. 2017 Dec;40(6):955-963. doi: 10.1007/s10865-017-9869-4. Epub 2017 Jun 21.


Text mining applied to electronic cardiovascular procedure reports to identify patients with trileaflet aortic stenosis and coronary artery disease.

Small AM, Kiss DH, Zlatsin Y, Birtwell DL, Williams H, Guerraty MA, Han Y, Anwaruddin S, Holmes JH, Chirinos JA, Wilensky RL, Giri J, Rader DJ.

J Biomed Inform. 2017 Aug;72:77-84. doi: 10.1016/j.jbi.2017.06.016. Epub 2017 Jun 15.


Left Ventricular Geometry, Blood Pressure, Arterial Hemodynamics, and Mortality After Ischemic Stroke.

Gillebert TC, Chirinos JA.

JACC Cardiovasc Imaging. 2018 Mar;11(3):383-385. doi: 10.1016/j.jcmg.2017.03.013. Epub 2017 Jun 14. No abstract available.


Late Systolic Myocardial Loading Is Associated With Left Atrial Dysfunction in Hypertension.

Chirinos JA, Phan TS, Syed AA, Hashmath Z, Oldland HG, Koppula MR, Tariq A, Javaid K, Miller R, Varakantam S, Dunde A, Neetha V, Akers SR.

Circ Cardiovasc Imaging. 2017 Jun;10(6):e006023. doi: 10.1161/CIRCIMAGING.116.006023.


Effects of organic and inorganic nitrate on aortic and carotid haemodynamics in heart failure with preserved ejection fraction.

Chirinos JA, Londono-Hoyos F, Zamani P, Beraun M, Haines P, Vasim I, Varakantam S, Phan TS, Cappola TP, Margulies KB, Townsend RR, Segers P.

Eur J Heart Fail. 2017 Nov;19(11):1507-1515. doi: 10.1002/ejhf.885. Epub 2017 May 25.


Erratum to: Deep Phenotyping of Systemic Arterial Hemodynamics in HFpEF (Part 1): Physiologic and Technical Considerations.

Chirinos JA.

J Cardiovasc Transl Res. 2017 Jun;10(3):260. doi: 10.1007/s12265-017-9745-1. No abstract available.


Deep Phenotyping of Systemic Arterial Hemodynamics in HFpEF (Part 2): Clinical and Therapeutic Considerations.

Chirinos JA.

J Cardiovasc Transl Res. 2017 Jun;10(3):261-274. doi: 10.1007/s12265-017-9736-2. Epub 2017 Apr 11. Review.


Deciphering Systolic-Diastolic Coupling in the Intact Heart.

Chirinos JA.

Hypertension. 2017 Apr;69(4):575-577. doi: 10.1161/HYPERTENSIONAHA.116.08849. Epub 2017 Feb 21. No abstract available.


Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction.

Zamani P, Akers S, Soto-Calderon H, Beraun M, Koppula MR, Varakantam S, Rawat D, Shiva-Kumar P, Haines PG, Chittams J, Townsend RR, Witschey WR, Segers P, Chirinos JA.

J Am Heart Assoc. 2017 Feb 20;6(2). pii: e004262. doi: 10.1161/JAHA.116.004262.

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