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Items: 13


Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models.

Liu X, Taftaf R, Kawaguchi M, Chang YF, Chen W, Entenberg D, Zhang Y, Gerratana L, Huang S, Patel DB, Tsui E, Adorno-Cruz V, Chirieleison SM, Cao Y, Harney AS, Patel S, Patsialou A, Shen Y, Avril S, Gilmore HL, Lathia JD, Abbott DW, Cristofanilli M, Condeelis JS, Liu H.

Cancer Discov. 2019 Jan;9(1):96-113. doi: 10.1158/2159-8290.CD-18-0065. Epub 2018 Oct 25.


Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.

Rathkey JK, Zhao J, Liu Z, Chen Y, Yang J, Kondolf HC, Benson BL, Chirieleison SM, Huang AY, Dubyak GR, Xiao TS, Li X, Abbott DW.

Sci Immunol. 2018 Aug 24;3(26). pii: eaat2738. doi: 10.1126/sciimmunol.aat2738.


Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.

Chirieleison SM, Rathkey JK, Abbott DW.

Sci Signal. 2018 Jul 17;11(539). pii: eaao3964. doi: 10.1126/scisignal.aao3964.


Live-cell visualization of gasdermin D-driven pyroptotic cell death.

Rathkey JK, Benson BL, Chirieleison SM, Yang J, Xiao TS, Dubyak GR, Huang AY, Abbott DW.

J Biol Chem. 2017 Sep 1;292(35):14649-14658. doi: 10.1074/jbc.M117.797217. Epub 2017 Jul 18.


Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.

Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW.

J Biol Chem. 2017 Jun 9;292(23):9666-9679. doi: 10.1074/jbc.M117.781500. Epub 2017 Apr 12.


Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity.

Dorand RD, Nthale J, Myers JT, Barkauskas DS, Avril S, Chirieleison SM, Pareek TK, Abbott DW, Stearns DS, Letterio JJ, Huang AY, Petrosiute A.

Science. 2016 Jul 22;353(6297):399-403. doi: 10.1126/science.aae0477. Epub 2016 Jul 21.


Synthetic Biology Reveals the Uniqueness of the RIP Kinase Domain.

Chirieleison SM, Kertesy SB, Abbott DW.

J Immunol. 2016 May 15;196(10):4291-7. doi: 10.4049/jimmunol.1502631. Epub 2016 Apr 4.


An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.

Perez JM, Chirieleison SM, Abbott DW.

Cell Rep. 2015 Jul 28;12(4):537-44. doi: 10.1016/j.celrep.2015.06.050. Epub 2015 Jul 16.


Pattern transformation with DNA circuits.

Chirieleison SM, Allen PB, Simpson ZB, Ellington AD, Chen X.

Nat Chem. 2013 Dec;5(12):1000-5. doi: 10.1038/nchem.1764. Epub 2013 Sep 29.


Generalized bacterial genome editing using mobile group II introns and Cre-lox.

Enyeart PJ, Chirieleison SM, Dao MN, Perutka J, Quandt EM, Yao J, Whitt JT, Keatinge-Clay AT, Lambowitz AM, Ellington AD.

Mol Syst Biol. 2013;9:685. doi: 10.1038/msb.2013.41.


Human muscle-derived cell populations isolated by differential adhesion rates: phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice.

Chirieleison SM, Feduska JM, Schugar RC, Askew Y, Deasy BM.

Tissue Eng Part A. 2012 Feb;18(3-4):232-41. doi: 10.1089/ten.TEA.2010.0553. Epub 2011 Oct 11.


Automated live cell imaging systems reveal dynamic cell behavior.

Chirieleison SM, Bissell TA, Scelfo CC, Anderson JE, Li Y, Koebler DJ, Deasy BM.

Biotechnol Prog. 2011 Jul;27(4):913-24. doi: 10.1002/btpr.629. Epub 2011 Jun 20. Review.


High harvest yield, high expansion, and phenotype stability of CD146 mesenchymal stromal cells from whole primitive human umbilical cord tissue.

Schugar RC, Chirieleison SM, Wescoe KE, Schmidt BT, Askew Y, Nance JJ, Evron JM, Peault B, Deasy BM.

J Biomed Biotechnol. 2009;2009:789526. doi: 10.1155/2009/789526. Epub 2009 Dec 16.

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