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Items: 1 to 50 of 103

1.

Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod.

Rozenblit M, Hendrickx W, Heguy A, Chiriboga L, Loomis C, Ray K, Darvishian F, Egeblad M, Demaria S, Marincola FM, Bedognetti D, Adams S.

Sci Rep. 2019 Jun 12;9(1):8572. doi: 10.1038/s41598-019-42784-9.

2.

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.

Hu H, Gehart H, Artegiani B, LÖpez-Iglesias C, Dekkers F, Basak O, van Es J, Chuva de Sousa Lopes SM, Begthel H, Korving J, van den Born M, Zou C, Quirk C, Chiriboga L, Rice CM, Ma S, Rios A, Peters PJ, de Jong YP, Clevers H.

Cell. 2018 Nov 29;175(6):1591-1606.e19. doi: 10.1016/j.cell.2018.11.013.

PMID:
30500538
3.

Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma.

Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, Riina HA, Nicolaides TP, Sulman EP, Cahill DP, Golfinos JG, Isse K, Saunders LR, Zagzag D, Placantonakis DG, Snuderl M, Chi AS.

Clin Cancer Res. 2019 Feb 15;25(4):1261-1271. doi: 10.1158/1078-0432.CCR-18-2312. Epub 2018 Nov 5.

PMID:
30397180
4.

Durable response to anti-PD-1 immunotherapy in epithelioid angiomyolipoma: a report on the successful treatment of a rare malignancy.

Lattanzi M, Deng FM, Chiriboga LA, Femia AN, Meehan SA, Iyer G, Voss MH, Sundatova Y, Huang WC, Balar AV.

J Immunother Cancer. 2018 Oct 1;6(1):97. doi: 10.1186/s40425-018-0415-x.

5.

Chibby is a weak regulator of β-catenin activity in gastric epithelium.

Li FQ, Chiriboga L, Black MA, Takemaru KI, Raffaniello RD.

J Cell Physiol. 2019 Feb;234(2):1871-1879. doi: 10.1002/jcp.27062. Epub 2018 Jul 31.

PMID:
30063079
6.

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.

Snuderl M, Kannan K, Pfaff E, Wang S, Stafford JM, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton SL, Zagzag D, Chiriboga L, Gardner SL, Wisoff JH, Golfinos JG, Capper D, Hovestadt V, Rosenblum MK, Placantonakis DG, LeBoeuf SE, Papagiannakopoulos TY, Chavez L, Ahsan S, Eberhart CG, Pfister SM, Jones DTW, Karajannis MA.

Nat Commun. 2018 Jul 20;9(1):2868. doi: 10.1038/s41467-018-05029-3.

7.

Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.

Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, Chiriboga L, Cullen J, Nahass RG, Lutgehetmann M, Toettcher JE, Wiles MV, Schwartz RE, Ploss A.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.

8.

Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus.

Burgess HM, Pourchet A, Hajdu CH, Chiriboga L, Frey AB, Mohr I.

Mol Ther Oncolytics. 2018 Jan 31;8:71-81. doi: 10.1016/j.omto.2018.01.001. eCollection 2018 Mar 30.

9.

Diagnostic Algorithmic Proposal Based on Comprehensive Immunohistochemical Evaluation of 297 Invasive Endocervical Adenocarcinomas.

Stolnicu S, Barsan I, Hoang L, Patel P, Chiriboga L, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ, Soslow RA.

Am J Surg Pathol. 2018 Aug;42(8):989-1000. doi: 10.1097/PAS.0000000000001090.

PMID:
29851704
10.

Membrane attack complex (mac) deposition in lupus nephritis is associated with hypertension and poor clinical response to treatment.

Wang S, Wu M, Chiriboga L, Zeck B, Belmont HM.

Semin Arthritis Rheum. 2018 Oct;48(2):256-262. doi: 10.1016/j.semarthrit.2018.01.004. Epub 2018 Jan 6.

PMID:
29395256
11.

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG.

Cell Rep. 2017 Oct 31;21(5):1267-1280. doi: 10.1016/j.celrep.2017.10.009.

12.

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.

Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG.

Oncotarget. 2017 May 23;8(39):64932-64953. doi: 10.18632/oncotarget.18117. eCollection 2017 Sep 12.

13.

Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination.

Gagner JP, Sarfraz Y, Ortenzi V, Alotaibi FM, Chiriboga LA, Tayyib AT, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Schmitt M, Lemercier G, Dembowsky K, Zagzag D.

Am J Pathol. 2017 Sep;187(9):2080-2094. doi: 10.1016/j.ajpath.2017.04.020. Epub 2017 Jul 20. Erratum in: Am J Pathol. 2017 Nov;187(11):2617.

14.

Mouse models of acute and chronic hepacivirus infection.

Billerbeck E, Wolfisberg R, Fahnøe U, Xiao JW, Quirk C, Luna JM, Cullen JM, Hartlage AS, Chiriboga L, Ghoshal K, Lipkin WI, Bukh J, Scheel TKH, Kapoor A, Rice CM.

Science. 2017 Jul 14;357(6347):204-208. doi: 10.1126/science.aal1962.

15.

Arrested Development: Infantile Hemangioma and the Stem Cell Teratogenic Hypothesis.

Harbi S, Park H, Gregory M, Lopez P, Chiriboga L, Mignatti P.

Lymphat Res Biol. 2017 Jun;15(2):153-165. doi: 10.1089/lrb.2016.0030. Epub 2017 May 18. Review.

PMID:
28520518
16.

Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.

Lerman I, Garcia-Hernandez ML, Rangel-Moreno J, Chiriboga L, Pan C, Nastiuk KL, Krolewski JJ, Sen A, Hammes SR.

Mol Cancer Res. 2017 Sep;15(9):1138-1152. doi: 10.1158/1541-7786.MCR-17-0003. Epub 2017 May 16.

17.

Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection.

Winer BY, Huang T, Low BE, Avery C, Pais MA, Hrebikova G, Siu E, Chiriboga L, Wiles MV, Ploss A.

Virology. 2017 Feb;502:63-72. doi: 10.1016/j.virol.2016.12.017. Epub 2016 Dec 19.

18.

Nuclear TBLR1 as an ER corepressor promotes cell proliferation, migration and invasion in breast and ovarian cancer.

Wu X, Zhan Y, Li X, Wei J, Santiago L, Daniels G, Deng F, Zhong X, Chiriboga L, Basch R, Xiong S, Dong Y, Zhang X, Lee P.

Am J Cancer Res. 2016 Oct 1;6(10):2351-2360. eCollection 2016.

19.

Infantile Hemangioma Originates From A Dysregulated But Not Fully Transformed Multipotent Stem Cell.

Harbi S, Wang R, Gregory M, Hanson N, Kobylarz K, Ryan K, Deng Y, Lopez P, Chiriboga L, Mignatti P.

Sci Rep. 2016 Oct 27;6:35811. doi: 10.1038/srep35811.

20.

Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells.

Billerbeck E, Mommersteeg MC, Shlomai A, Xiao JW, Andrus L, Bhatta A, Vercauteren K, Michailidis E, Dorner M, Krishnan A, Charlton MR, Chiriboga L, Rice CM, de Jong YP.

J Hepatol. 2016 Aug;65(2):334-43. doi: 10.1016/j.jhep.2016.04.022. Epub 2016 May 2.

21.

NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.

Panaccione A, Chang MT, Carbone BE, Guo Y, Moskaluk CA, Virk RK, Chiriboga L, Prasad ML, Judson B, Mehra S, Yarbrough WG, Ivanov SV.

Clin Cancer Res. 2016 Apr 15;22(8):2083-95. doi: 10.1158/1078-0432.CCR-15-2208.

22.

Endothelin-1 in the tumor microenvironment correlates with melanoma invasion.

Chiriboga L, Meehan S, Osman I, Glick M, de la Cruz G, Howell BS, Friedman-Jiménez G, Schneider RJ, Jamal S.

Melanoma Res. 2016 Jun;26(3):236-44. doi: 10.1097/CMR.0000000000000235.

PMID:
26825037
23.

Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice.

Scull MA, Shi C, de Jong YP, Gerold G, Ries M, von Schaewen M, Donovan BM, Labitt RN, Horwitz JA, Gaska JM, Hrebikova G, Xiao JW, Flatley B, Fung C, Chiriboga L, Walker CM, Evans DT, Rice CM, Ploss A.

Hepatology. 2015 Jul;62(1):57-67. doi: 10.1002/hep.27773. Epub 2015 Apr 15.

24.

Resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with high-risk melanoma.

Sabado RL, Pavlick A, Gnjatic S, Cruz CM, Vengco I, Hasan F, Spadaccia M, Darvishian F, Chiriboga L, Holman RM, Escalon J, Muren C, Escano C, Yepes E, Sharpe D, Vasilakos JP, Rolnitzsky L, Goldberg J, Mandeli J, Adams S, Jungbluth A, Pan L, Venhaus R, Ott PA, Bhardwaj N.

Cancer Immunol Res. 2015 Mar;3(3):278-287. doi: 10.1158/2326-6066.CIR-14-0202. Epub 2015 Jan 29.

25.

Broadly neutralizing antibodies abrogate established hepatitis C virus infection.

de Jong YP, Dorner M, Mommersteeg MC, Xiao JW, Balazs AB, Robbins JB, Winer BY, Gerges S, Vega K, Labitt RN, Donovan BM, Giang E, Krishnan A, Chiriboga L, Charlton MR, Burton DR, Baltimore D, Law M, Rice CM, Ploss A.

Sci Transl Med. 2014 Sep 17;6(254):254ra129. doi: 10.1126/scitranslmed.3009512.

26.

Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

Fernández P, Perez-Aso M, Smith G, Wilder T, Trzaska S, Chiriboga L, Franks A Jr, Robson SC, Cronstein BN, Chan ESL.

Am J Pathol. 2013 Dec;183(6):1740-1746. doi: 10.1016/j.ajpath.2013.08.024.

27.

A link between premenopausal iron deficiency and breast cancer malignancy.

Jian J, Yang Q, Shao Y, Axelrod D, Smith J, Singh B, Krauter S, Chiriboga L, Yang Z, Li J, Huang X.

BMC Cancer. 2013 Jun 24;13:307. doi: 10.1186/1471-2407-13-307.

28.

Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma.

Pass HI, Levin SM, Harbut MR, Melamed J, Chiriboga L, Donington J, Huflejt M, Carbone M, Chia D, Goodglick L, Goodman GE, Thornquist MD, Liu G, de Perrot M, Tsao MS, Goparaju C.

N Engl J Med. 2012 Oct 11;367(15):1417-27. doi: 10.1056/NEJMoa1115050. Erratum in: N Engl J Med. 2012 Nov;367(18):1768.

29.

Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer.

Adams S, Kozhaya L, Martiniuk F, Meng TC, Chiriboga L, Liebes L, Hochman T, Shuman N, Axelrod D, Speyer J, Novik Y, Tiersten A, Goldberg JD, Formenti SC, Bhardwaj N, Unutmaz D, Demaria S.

Clin Cancer Res. 2012 Dec 15;18(24):6748-57. doi: 10.1158/1078-0432.CCR-12-1149. Epub 2012 Jul 5.

30.

Pharmacological blockade of adenosine A2A receptors diminishes scarring.

Perez-Aso M, Chiriboga L, Cronstein BN.

FASEB J. 2012 Oct;26(10):4254-63. doi: 10.1096/fj.12-209627. Epub 2012 Jul 5.

31.

Impact of decalcification on receptor status in breast cancer.

Darvishian F, Singh B, Krauter S, Chiriboga L, Gangi MD, Melamed J.

Breast J. 2011 Nov-Dec;17(6):689-91. doi: 10.1111/j.1524-4741.2011.01168.x. Epub 2011 Oct 17. No abstract available.

PMID:
21999708
32.

The numbers of FoxP3+ lymphocytes in sentinel lymph nodes of breast cancer patients correlate with primary tumor size but not nodal status.

Gupta R, Babb JS, Singh B, Chiriboga L, Liebes L, Adams S, Demaria S.

Cancer Invest. 2011 Jul;29(6):419-25. doi: 10.3109/07357907.2011.585193.

33.

R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma.

Williams SC, Karajannis MA, Chiriboga L, Golfinos JG, von Deimling A, Zagzag D.

Acta Neuropathol. 2011 Feb;121(2):279-81. doi: 10.1007/s00401-010-0790-y. Epub 2010 Dec 24. No abstract available.

34.

Efficient in vivo microRNA targeting of liver metastasis.

Huynh C, Segura MF, Gaziel-Sovran A, Menendez S, Darvishian F, Chiriboga L, Levin B, Meruelo D, Osman I, Zavadil J, Marcusson EG, Hernando E.

Oncogene. 2011 Mar 24;30(12):1481-8. doi: 10.1038/onc.2010.523. Epub 2010 Nov 22.

PMID:
21102518
35.

Levels of elevated circulating endothelial cell decline after tumor resection in patients with pancreatic ductal adenocarcinoma.

Sabbaghian MS, Rothberger G, Alongi AP, Gagner JP, Goldberg JD, Rolnitzky L, Chiriboga L, Hajdu CH, Zagzag D, Basch R, Shamamian P.

Anticancer Res. 2010 Jul;30(7):2911-7.

PMID:
20683032
36.

Fascin over expression is associated with dysplastic changes in sinonasal inverted papillomas: a study of 47 cases.

Wu HH, Zafar S, Huan Y, Yee H, Chiriboga L, Wang BY.

Head Neck Pathol. 2009 Sep;3(3):212-6. doi: 10.1007/s12105-009-0133-2. Epub 2009 Aug 14.

37.

ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma.

Ammoun S, Cunliffe CH, Allen JC, Chiriboga L, Giancotti FG, Zagzag D, Hanemann CO, Karajannis MA.

Neuro Oncol. 2010 Aug;12(8):834-43. doi: 10.1093/neuonc/noq012. Epub 2010 Feb 11.

38.

Androgen receptor coactivator p44/Mep50 in breast cancer growth and invasion.

Peng Y, Li Y, Gellert LL, Zou X, Wang J, Singh B, Xu R, Chiriboga L, Daniels G, Pan R, Zhang DY, Garabedian MJ, Schneider RJ, Wang Z, Lee P.

J Cell Mol Med. 2010 Dec;14(12):2780-9. doi: 10.1111/j.1582-4934.2009.00936.x.

39.

Adenosine signaling contributes to ethanol-induced fatty liver in mice.

Peng Z, Borea PA, Varani K, Wilder T, Yee H, Chiriboga L, Blackburn MR, Azzena G, Resta G, Cronstein BN.

J Clin Invest. 2009 Mar;119(3):582-94. doi: 10.1172/JCI37409. Epub 2009 Feb 16. Erratum in: J Clin Invest. 2009 Apr;119(4):1052. Varani, Katia [added].

40.

Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection.

Gonzalez SA, Fiel MI, Sauk J, Canchis PW, Liu RC, Chiriboga L, Yee HT, Jacobson IM, Talal AH.

J Viral Hepat. 2009 Feb;16(2):141-8. doi: 10.1111/j.1365-2893.2008.01052.x. Epub 2008 Oct 24.

PMID:
19175868
41.

Expression of CD70 and the TH17 transcription factor RORgammaT in human contact dermatitis.

Martiniuk F, Lee DS, Gaspari A, Yee H, Chiriboga L, Huie M, Tchou-Wong KM, Levis WR.

J Drugs Dermatol. 2008 Oct;7(10):956-60.

PMID:
19112760
42.

Stromal anti-apoptotic androgen receptor target gene c-FLIP in prostate cancer.

Ye H, Li Y, Melamed J, Pearce P, Wei J, Chiriboga L, Wang Z, Osman I, Lee P.

J Urol. 2009 Feb;181(2):872-7. doi: 10.1016/j.juro.2008.10.064. Epub 2008 Dec 17.

PMID:
19095249
43.

Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C.

Zeremski M, Petrovic LM, Chiriboga L, Brown QB, Yee HT, Kinkhabwala M, Jacobson IM, Dimova R, Markatou M, Talal AH.

Hepatology. 2008 Nov;48(5):1440-50. doi: 10.1002/hep.22500.

44.

Expression of pax8 as a useful marker in distinguishing ovarian carcinomas from mammary carcinomas.

Nonaka D, Chiriboga L, Soslow RA.

Am J Surg Pathol. 2008 Oct;32(10):1566-71. doi: 10.1097/PAS.0b013e31816d71ad.

PMID:
18724243
45.

High-grade glioma before and after treatment with radiation and Avastin: initial observations.

Fischer I, Cunliffe CH, Bollo RJ, Raza S, Monoky D, Chiriboga L, Parker EC, Golfinos JG, Kelly PJ, Knopp EA, Gruber ML, Zagzag D, Narayana A.

Neuro Oncol. 2008 Oct;10(5):700-8. doi: 10.1215/15228517-2008-042. Epub 2008 Aug 12.

46.

Sox10: a pan-schwannian and melanocytic marker.

Nonaka D, Chiriboga L, Rubin BP.

Am J Surg Pathol. 2008 Sep;32(9):1291-8. doi: 10.1097/PAS.0b013e3181658c14.

PMID:
18636017
47.

Ecto-5'-nucleotidase (CD73)-mediated extracellular adenosine production plays a critical role in hepatic fibrosis.

Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN.

Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):821-4. doi: 10.1080/15257770802146403. Review.

PMID:
18600546
48.

Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures.

Zagzag D, Esencay M, Mendez O, Yee H, Smirnova I, Huang Y, Chiriboga L, Lukyanov E, Liu M, Newcomb EW.

Am J Pathol. 2008 Aug;173(2):545-60. doi: 10.2353/ajpath.2008.071197. Epub 2008 Jul 3.

49.

MASH1: a useful marker in differentiating pulmonary small cell carcinoma from Merkel cell carcinoma.

Ralston J, Chiriboga L, Nonaka D.

Mod Pathol. 2008 Nov;21(11):1357-62. doi: 10.1038/modpathol.2008.118. Epub 2008 Jun 27.

50.

Glioma-like proliferation within tissues excised as tubers in patients with tuberous sclerosis complex.

Fischer I, Cunliffe C, Bollo RJ, Weiner HL, Devinsky O, Ruiz-Tachiquin ME, Venuto T, Pearlman A, Chiriboga L, Schneider RJ, Ostrer H, Miller DC.

Acta Neuropathol. 2008 Jul;116(1):67-77. doi: 10.1007/s00401-008-0391-1. Epub 2008 Jun 26.

PMID:
18581125

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