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Items: 11

1.

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.

Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM.

Cell Rep. 2019 Jun 11;27(11):3269-3283.e6. doi: 10.1016/j.celrep.2019.05.040.

2.

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle.

Martin S, Chiramel AI, Schmidt ML, Chen YC, Whitt N, Watt A, Dunham EC, Shifflett K, Traeger S, Leske A, Buehler E, Martellaro C, Brandt J, Wendt L, Müller A, Peitsch S, Best SM, Stech J, Finke S, Römer-Oberdörfer A, Groseth A, Feldmann H, Hoenen T.

Genome Med. 2018 Aug 7;10(1):58. doi: 10.1186/s13073-018-0570-1.

3.

Unique Francisella Phosphatidylethanolamine Acts as a Potent Anti-Inflammatory Lipid.

Ireland R, Schwarz B, Nardone G, Wehrly TD, Broeckling CD, Chiramel AI, Best SM, Bosio CM.

J Innate Immun. 2018;10(4):291-305. doi: 10.1159/000489504. Epub 2018 Jul 3.

4.

Role of autophagy in Zika virus infection and pathogenesis.

Chiramel AI, Best SM.

Virus Res. 2018 Aug 2;254:34-40. doi: 10.1016/j.virusres.2017.09.006. Epub 2017 Sep 9. Review.

5.

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection.

Dutta M, Robertson SJ, Okumura A, Scott DP, Chang J, Weiss JM, Sturdevant GL, Feldmann F, Haddock E, Chiramel AI, Ponia SS, Dougherty JD, Katze MG, Rasmussen AL, Best SM.

Cell Rep. 2017 Jan 17;18(3):816-829. doi: 10.1016/j.celrep.2016.12.069.

6.

FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga.

Chiramel AI, Dougherty JD, Nair V, Robertson SJ, Best SM.

J Infect Dis. 2016 Oct 15;214(suppl 3):S319-S325. Epub 2016 Aug 10.

7.

Alisporivir Has Limited Antiviral Effects Against Ebola Virus Strains Makona and Mayinga.

Chiramel AI, Banadyga L, Dougherty JD, Falzarano D, Martellaro C, Brees D, Taylor RT, Ebihara H, Best SM.

J Infect Dis. 2016 Oct 15;214(suppl 3):S355-S359. Epub 2016 Aug 10.

8.

Assessing the contribution of interferon antagonism to the virulence of West African Ebola viruses.

Dunham EC, Banadyga L, Groseth A, Chiramel AI, Best SM, Ebihara H, Feldmann H, Hoenen T.

Nat Commun. 2015 Aug 5;6:8000. doi: 10.1038/ncomms9000.

9.

Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.

Lubick KJ, Robertson SJ, McNally KL, Freedman BA, Rasmussen AL, Taylor RT, Walts AD, Tsuruda S, Sakai M, Ishizuka M, Boer EF, Foster EC, Chiramel AI, Addison CB, Green R, Kastner DL, Katze MG, Holland SM, Forlino A, Freeman AF, Boehm M, Yoshii K, Best SM.

Cell Host Microbe. 2015 Jul 8;18(1):61-74. doi: 10.1016/j.chom.2015.06.007.

10.

Divergent roles of autophagy in virus infection.

Chiramel AI, Brady NR, Bartenschlager R.

Cells. 2013 Jan 25;2(1):83-104. doi: 10.3390/cells2010083.

11.

miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells.

Kovaleva V, Mora R, Park YJ, Plass C, Chiramel AI, Bartenschlager R, Döhner H, Stilgenbauer S, Pscherer A, Lichter P, Seiffert M.

Cancer Res. 2012 Apr 1;72(7):1763-72. doi: 10.1158/0008-5472.CAN-11-3671. Epub 2012 Feb 20.

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