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Items: 28

1.

Tumor cells endowed with professional antigen-presenting cell functions prime PBLs to generate antitumor CTLs.

Chiozzini C, Olivetta E, Sanchez M, Arenaccio C, Ferrantelli F, Leone P, Federico M.

J Mol Med (Berl). 2019 Aug;97(8):1139-1153. doi: 10.1007/s00109-019-01797-7. Epub 2019 Jun 3.

PMID:
31161312
2.

DNA Vectors Generating Engineered Exosomes Potential CTL Vaccine Candidates Against AIDS, Hepatitis B, and Tumors.

Ferrantelli F, Manfredi F, Chiozzini C, Anticoli S, Olivetta E, Arenaccio C, Federico M.

Mol Biotechnol. 2018 Nov;60(11):773-782. doi: 10.1007/s12033-018-0114-3.

PMID:
30167966
3.

Exosomes in Therapy: Engineering, Pharmacokinetics and Future Applications.

Arenaccio C, Chiozzini C, Ferrantelli F, Leone P, Olivetta E, Federico M.

Curr Drug Targets. 2019;20(1):87-95. doi: 10.2174/1389450119666180521100409.

PMID:
29779478
4.

Engineered exosomes emerging from muscle cells break immune tolerance to HER2 in transgenic mice and induce antigen-specific CTLs upon challenge by human dendritic cells.

Anticoli S, Aricò E, Arenaccio C, Manfredi F, Chiozzini C, Olivetta E, Ferrantelli F, Lattanzi L, D'Urso MT, Proietti E, Federico M.

J Mol Med (Berl). 2018 Feb;96(2):211-221. doi: 10.1007/s00109-017-1617-2. Epub 2017 Dec 27.

PMID:
29282521
5.

An Exosome-Based Vaccine Platform Imparts Cytotoxic T Lymphocyte Immunity Against Viral Antigens.

Anticoli S, Manfredi F, Chiozzini C, Arenaccio C, Olivetta E, Ferrantelli F, Capocefalo A, Falcone E, Ruggieri A, Federico M.

Biotechnol J. 2018 Apr;13(4):e1700443. doi: 10.1002/biot.201700443. Epub 2018 Mar 24.

PMID:
29274250
6.

Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation.

Di Bonito P, Chiozzini C, Arenaccio C, Anticoli S, Manfredi F, Olivetta E, Ferrantelli F, Falcone E, Ruggieri A, Federico M.

Int J Nanomedicine. 2017 Jun 23;12:4579-4591. doi: 10.2147/IJN.S131309. eCollection 2017.

7.

Trans-dissemination of exosomes from HIV-1-infected cells fosters both HIV-1 trans-infection in resting CD4+ T lymphocytes and reactivation of the HIV-1 reservoir.

Chiozzini C, Arenaccio C, Olivetta E, Anticoli S, Manfredi F, Ferrantelli F, d'Ettorre G, Schietroma I, Andreotti M, Federico M.

Arch Virol. 2017 Sep;162(9):2565-2577. doi: 10.1007/s00705-017-3391-4. Epub 2017 May 4.

PMID:
28474225
8.

The CD8⁺ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIXTM Adjuvant.

Manfredi F, di Bonito P, Ridolfi B, Anticoli S, Arenaccio C, Chiozzini C, Baz Morelli A, Federico M.

Vaccines (Basel). 2016 Nov 9;4(4). pii: E42.

9.

Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1.

Arenaccio C, Anticoli S, Manfredi F, Chiozzini C, Olivetta E, Federico M.

Retrovirology. 2015 Oct 26;12:87. doi: 10.1186/s12977-015-0216-y.

10.

HIV-1 TAT and IMMUNE DYSREGULATION in AIDS PATHOGENESIS: a THERAPEUTIC TARGET.

Chiozzini C, Toschi E.

Curr Drug Targets. 2016;17(1):33-45. Review.

PMID:
26302810
11.

HPV-E7 delivered by engineered exosomes elicits a protective CD8⁺ T cell-mediated immune response.

Di Bonito P, Ridolfi B, Columba-Cabezas S, Giovannelli A, Chiozzini C, Manfredi F, Anticoli S, Arenaccio C, Federico M.

Viruses. 2015 Mar 9;7(3):1079-99. doi: 10.3390/v7031079.

12.

Surface-bound Tat inhibits antigen-specific CD8+ T-cell activation in an integrin-dependent manner.

Chiozzini C, Collacchi B, Nappi F, Bauer T, Arenaccio C, Tripiciano A, Longo O, Ensoli F, Cafaro A, Ensoli B, Federico M.

AIDS. 2014 Sep 24;28(15):2189-200. doi: 10.1097/QAD.0000000000000389.

PMID:
25313583
13.

Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism.

Arenaccio C, Chiozzini C, Columba-Cabezas S, Manfredi F, Affabris E, Baur A, Federico M.

J Virol. 2014 Oct;88(19):11529-39. doi: 10.1128/JVI.01712-14. Epub 2014 Jul 23.

14.

Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1.

Arenaccio C, Chiozzini C, Columba-Cabezas S, Manfredi F, Federico M.

Retrovirology. 2014 Jun 12;11:46. doi: 10.1186/1742-4690-11-46.

15.

The HIV protease inhibitor indinavir down-regulates the expression of the pro-angiogenic MT1-MMP by human endothelial cells.

Barillari G, Iovane A, Bacigalupo I, Labbaye C, Chiozzini C, Sernicola L, Quaranta MT, Falchi M, Sgadari C, Ensoli B.

Angiogenesis. 2014 Oct;17(4):831-8. doi: 10.1007/s10456-014-9430-9. Epub 2014 Apr 10.

PMID:
24719186
16.

HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation.

Olivetta E, Tirelli V, Chiozzini C, Scazzocchio B, Romano I, Arenaccio C, Sanchez M.

PLoS One. 2014 Apr 4;9(4):e93699. doi: 10.1371/journal.pone.0093699. eCollection 2014.

17.

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies.

Monini P, Cafaro A, Srivastava IK, Moretti S, Sharma VA, Andreini C, Chiozzini C, Ferrantelli F, Cossut MR, Tripiciano A, Nappi F, Longo O, Bellino S, Picconi O, Fanales-Belasio E, Borsetti A, Toschi E, Schiavoni I, Bacigalupo I, Kan E, Sernicola L, Maggiorella MT, Montin K, Porcu M, Leone P, Leone P, Collacchi B, Palladino C, Ridolfi B, Falchi M, Macchia I, Ulmer JB, Buttò S, Sgadari C, Magnani M, Federico MP, Titti F, Banci L, Dallocchio F, Rappuoli R, Ensoli F, Barnett SW, Garaci E, Ensoli B.

PLoS One. 2012;7(11):e48781. doi: 10.1371/journal.pone.0048781. Epub 2012 Nov 13.

18.

A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.

Ma Q, Cavallin LE, Leung HJ, Chiozzini C, Goldschmidt-Clermont PJ, Mesri EA.

Antioxid Redox Signal. 2013 Jan 1;18(1):80-90. doi: 10.1089/ars.2012.4584. Epub 2012 Aug 20.

19.

Human immunodeficiency virus protease inhibitors reduce the growth of human tumors via a proteasome-independent block of angiogenesis and matrix metalloproteinases.

Toschi E, Sgadari C, Malavasi L, Bacigalupo I, Chiozzini C, Carlei D, Compagnoni D, Bellino S, Bugarini R, Falchi M, Palladino C, Leone P, Barillari G, Monini P, Ensoli B.

Int J Cancer. 2011 Jan 1;128(1):82-93. doi: 10.1002/ijc.25550.

20.

Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles.

Nappi F, Chiozzini C, Bordignon V, Borsetti A, Bellino S, Cippitelli M, Barillari G, Caputo A, Tyagi M, Giacca M, Ensoli B.

J Gene Med. 2009 Nov;11(11):955-65. doi: 10.1002/jgm.1381.

PMID:
19653251
21.

Primary effusion lymphoma cells undergoing human herpesvirus type 8 productive infection produce C-type retroviral particles.

Tinari A, Superti F, Ammendolia MG, Chiozzini C, Hohenadl C, Leone P, Nappi F, Nicoletti M, Borsetti A, Marchetti M, Ensoli B, Monini P.

Int J Immunopathol Pharmacol. 2008 Oct-Dec;21(4):999-1006.

PMID:
19144286
22.

In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.

Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA.

Cancer Cell. 2007 Mar;11(3):245-58. Erratum in: Cancer Cell. 2007 May;11(5):471.

23.

HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway.

Toschi E, Bacigalupo I, Strippoli R, Chiozzini C, Cereseto A, Falchi M, Nappi F, Sgadari C, Barillari G, Mainiero F, Ensoli B.

Mol Biol Cell. 2006 Apr;17(4):1985-94. Epub 2006 Jan 25.

24.

[HIV protease inhibitors for the treatment of Kaposi's sarcoma].

Grosso G, Sgadari C, Barillari G, Toschi E, Bacigalupo I, Carlei D, Palladino C, Baccarini S, Malavasi L, Moracci G, Leone P, Chiozzini C, Monini P, Ensoli B.

Recenti Prog Med. 2003 Feb;94(2):69-74. Review. Italian.

PMID:
12908373
25.

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

Bais C, Van Geelen A, Eroles P, Mutlu A, Chiozzini C, Dias S, Silverstein RL, Rafii S, Mesri EA.

Cancer Cell. 2003 Feb;3(2):131-43.

26.

Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-alpha therapy: a case report.

Monini P, Sirianni MC, Franco M, Vincenzi L, Topino S, Goletti D, Leone P, Leone P, Chiozzini C, Nicastri E, Andreoni M, Borduagni O, Sgadari C, Rezza G, Stürzl M, Ensoli B.

Clin Infect Dis. 2001 Nov 15;33(10):1782-5. Epub 2001 Oct 12.

PMID:
11641829
27.

Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma.

Monini P, Colombini S, Stürzl M, Goletti D, Cafaro A, Sgadari C, Buttò S, Franco M, Leone P, Fais S, Leone P, Melucci-Vigo G, Chiozzini C, Carlini F, Ascherl G, Cornali E, Zietz C, Ramazzotti E, Ensoli F, Andreoni M, Pezzotti P, Rezza G, Yarchoan R, Gallo RC, Ensoli B.

Blood. 1999 Jun 15;93(12):4044-58.

PMID:
10361101
28.

Alpha interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cells.

Monini P, Carlini F, Stürzl M, Rimessi P, Superti F, Franco M, Melucci-Vigo G, Cafaro A, Goletti D, Sgadari C, Butto' S, Leone P, Chiozzini C, Barresi C, Tinari A, Bonaccorsi A, Capobianchi MR, Giuliani M, di Carlo A, Andreoni M, Rezza G, Ensoli B.

J Virol. 1999 May;73(5):4029-41.

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