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Items: 11


A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.

Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG.

BMC Genomics. 2018 Jan 10;19(1):37. doi: 10.1186/s12864-017-4375-1.


Alternative lengthening of human telomeres is a conservative DNA replication process with features of break-induced replication.

Roumelioti FM, Sotiriou SK, Katsini V, Chiourea M, Halazonetis TD, Gagos S.

EMBO Rep. 2016 Dec;17(12):1731-1737. Epub 2016 Oct 19.


Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.

Dan J, Liu Y, Liu N, Chiourea M, Okuka M, Wu T, Ye X, Mou C, Wang L, Wang L, Yin Y, Yuan J, Zuo B, Wang F, Li Z, Pan X, Yin Z, Chen L, Keefe DL, Gagos S, Xiao A, Liu L.

Dev Cell. 2014 Apr 14;29(1):7-19. doi: 10.1016/j.devcel.2014.03.004.


Molecular and cytogenetic changes in multi-drug resistant cancer cells and their influence on new compounds testing.

Podolski-Renić A, Jadranin M, Stanković T, Banković J, Stojković S, Chiourea M, Aljančić I, Vajs V, Tešević V, Ruždijić S, Gagos S, Tanić N, Pešić M.

Cancer Chemother Pharmacol. 2013 Sep;72(3):683-97. doi: 10.1007/s00280-013-2247-1. Epub 2013 Aug 10.


The roles of telomerase in the generation of polyploidy during neoplastic cell growth.

Christodoulidou A, Raftopoulou C, Chiourea M, Papaioannou GK, Hoshiyama H, Wright WE, Shay JW, Gagos S.

Neoplasia. 2013 Feb;15(2):156-68.


The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation.

Kohzaki M, Chiourea M, Versini G, Adachi N, Takeda S, Gagos S, Halazonetis TD.

Carcinogenesis. 2012 Jun;33(6):1203-10. doi: 10.1093/carcin/bgs149. Epub 2012 Apr 16.


Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells.

Wang F, Yin Y, Ye X, Liu K, Zhu H, Wang L, Chiourea M, Okuka M, Ji G, Dan J, Zuo B, Li M, Zhang Q, Liu N, Chen L, Pan X, Gagos S, Keefe DL, Liu L.

Cell Res. 2012 Apr;22(4):757-68. doi: 10.1038/cr.2011.201. Epub 2011 Dec 20.


Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres.

Mitchell MA, Johnson JE, Pascarelli K, Beeharry N, Chiourea M, Gagos S, Lev D, von Mehren M, Kipling D, Broccoli D.

Mol Cancer Ther. 2010 Mar;9(3):682-92. doi: 10.1158/1535-7163.MCT-09-0705. Epub 2010 Mar 2.


Pericentromeric instability and spontaneous emergence of human neoacrocentric and minute chromosomes in the alternative pathway of telomere lengthening.

Gagos S, Chiourea M, Christodoulidou A, Apostolou E, Raftopoulou C, Deustch S, Jefford CE, Irminger-Finger I, Shay JW, Antonarakis SE.

Cancer Res. 2008 Oct 1;68(19):8146-55. doi: 10.1158/0008-5472.CAN-08-0945.


Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity.

Gagos S, Papaioannou G, Chiourea M, Merk-Loretti S, Jefford CE, Mikou P, Irminger-Finger I, Liossi A, Blouin JL, Dahoun S.

Mol Cytogenet. 2008 Aug 22;1:20. doi: 10.1186/1755-8166-1-20.

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