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Human-Induced Pluripotent Stem Cells and Herbal Small-Molecule Drugs for Treatment of Alzheimer's Disease.

Wuli W, Tsai ST, Chiou TW, Harn HJ.

Int J Mol Sci. 2020 Feb 16;21(4). pii: E1327. doi: 10.3390/ijms21041327. Review.


Phosphate excess increases susceptibility to pathogen infection in rice.

Campos-Soriano L, Bundó M, Bach-Pages M, Chiang SF, Chiou TJ, San Segundo B.

Mol Plant Pathol. 2020 Apr;21(4):555-570. doi: 10.1111/mpp.12916. Epub 2020 Feb 19.


DNA methylation-mediated Siglec-7 regulation in natural killer cells via two 5' promoter CpG sites.

Huang HT, Su SC, Chiou TJ, Lin YH, Shih YC, Wu YX, Fan TH, Twu YC.

Immunology. 2020 Feb 6. doi: 10.1111/imm.13179. [Epub ahead of print]


The landscape of BCR-ABL mutations in patients with Philadelphia chromosome-positive leukaemias in the era of second-generation tyrosine kinase inhibitors.

Chien SH, Liu HM, Chen PM, Ko PS, Lin JS, Chen YJ, Lee LH, Hsiao LT, Chiou TJ, Gau JP, Yang MH, Liu CY.

Hematol Oncol. 2020 Feb 3. doi: 10.1002/hon.2721. [Epub ahead of print]


European Group for Blood and Marrow Transplantation score correlates with outcomes of older patients undergoing allogeneic hematopoietic stem cell transplantation.

Chien SH, Liu YC, Liu CJ, Ko PS, Wang HY, Hsiao LT, Lin JS, Chiou TJ, Liu CY, Gau JP.

J Chin Med Assoc. 2020 Mar;83(3):238-244. doi: 10.1097/JCMA.0000000000000255.


Transplantation with GXHPC1 for Liver Cirrhosis: Phase 1 Trial.

Huang KC, Chuang MH, Lin ZS, Lin YC, Chen CH, Chang CL, Huang PC, Syu WS, Chiou TW, Hong ZH, Tsai YC, Harn HJ, Lin PC, Lin SZ.

Cell Transplant. 2019 Dec;28(1_suppl):100S-111S. doi: 10.1177/0963689719884885. Epub 2019 Nov 14.


Extended-Release Formulation and Medication Adherence.

Romley JA, Xie Z, Chiou T, Goldman D, Peters AL.

J Gen Intern Med. 2020 Jan;35(1):354-356. doi: 10.1007/s11606-019-05275-1. No abstract available.


Upstream Open Reading Frame and Phosphate-Regulated Expression of Rice OsNLA1 Controls Phosphate Transport and Reproduction.

Yang SY, Lu WC, Ko SS, Sun CM, Hung JC, Chiou TJ.

Plant Physiol. 2020 Jan;182(1):393-407. doi: 10.1104/pp.19.01101. Epub 2019 Oct 28.


Nasopharyngeal Lymphoma: A 22-Year Review of 35 Cases.

Hsueh CY, Yang CF, Gau JP, Kuan EC, Ho CY, Chiou TJ, Hsiao LT, Lin TA, Lan MY.

J Clin Med. 2019 Oct 3;8(10). pii: E1604. doi: 10.3390/jcm8101604.


Expression of protocadherin-γC4 protein in the rat brain.

Miralles CP, Taylor MJ, Bear J Jr, Fekete CD, George S, Li Y, Bonhomme B, Chiou TT, De Blas AL.

J Comp Neurol. 2020 Apr 1;528(5):840-864. doi: 10.1002/cne.24783. Epub 2019 Nov 6.


Structure-Function Analysis Reveals Amino Acid Residues of Arabidopsis Phosphate Transporter AtPHT1;1 Crucial for Its Activity.

Liao YY, Li JL, Pan RL, Chiou TJ.

Front Plant Sci. 2019 Sep 19;10:1158. doi: 10.3389/fpls.2019.01158. eCollection 2019.


Effect of ethanol extract from Lactobacillus plantarum TWK10-fermented soymilk on wound healing in streptozotocin-induced diabetic rat.

Chuang YC, Cheng MC, Lee CC, Chiou TY, Tsai TY.

AMB Express. 2019 Oct 11;9(1):163. doi: 10.1186/s13568-019-0886-2.


Draft Genome Sequence of Sporolactobacillus inulinus NBRC 111894, Isolated from Kôso, a Japanese Sugar-Vegetable Fermented Beverage.

Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T.

Microbiol Resour Announc. 2019 Oct 10;8(41). pii: e00751-19. doi: 10.1128/MRA.00751-19.


The Affordable Care Act and Health Insurance Coverage Among People With Diagnosed and Undiagnosed Diabetes: Data From the National Health and Nutrition Examination Survey.

Myerson R, Romley J, Chiou T, Peters AL, Goldman D.

Diabetes Care. 2019 Nov;42(11):e179-e180. doi: 10.2337/dc19-0081. Epub 2019 Sep 23. No abstract available.


Trends in Racial and Ethnic Disparities in Diabetes-Related Complications, 1997-2017.

Chiou T, Tsugawa Y, Goldman D, Myerson R, Kahn M, Romley JA.

J Gen Intern Med. 2020 Mar;35(3):950-951. doi: 10.1007/s11606-019-05308-9. Epub 2019 Sep 11. No abstract available.


TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression.

Huang CH, Liao YJ, Chiou TJ, Huang HT, Lin YH, Twu YC.

Immunobiology. 2019 Sep;224(5):649-658. doi: 10.1016/j.imbio.2019.07.002. Epub 2019 Aug 9.


Risk Prediction for Early Mortality in Patients with Newly Diagnosed Primary CNS Lymphoma.

Lin CH, Yang CF, Yang HC, Fay LY, Yeh CM, Kuan AS, Wang HY, Gau JP, Hsiao LT, Chiou TJ, Chen PM, Liu YC, Ko PS, Liu JH, Liu CJ.

J Cancer. 2019 Jul 5;10(17):3958-3966. doi: 10.7150/jca.32467. eCollection 2019.


Risk factors and clinical features for post-transplant thoracic air-leak syndrome in adult patients receiving allogeneic haematopoietic stem cell transplantation.

Liu YC, Chou YH, Ko PS, Wang HY, Fan NW, Liu CJ, Hsiao LT, Chien SH, Chiou TJ, Liu JH, Gau JP.

Sci Rep. 2019 Aug 13;9(1):11795. doi: 10.1038/s41598-019-48308-9.


Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in adults with haematological malignancies: a phase 3, randomised, clinical trial and post-hoc efficacy analysis.

Dagnew AF, Ilhan O, Lee WS, Woszczyk D, Kwak JY, Bowcock S, Sohn SK, Rodriguez Macías G, Chiou TJ, Quiel D, Aoun M, Navarro Matilla MB, de la Serna J, Milliken S, Murphy J, McNeil SA, Salaun B, Di Paolo E, Campora L, López-Fauqued M, El Idrissi M, Schuind A, Heineman TC, Van den Steen P, Oostvogels L; Zoster-039 study group.

Lancet Infect Dis. 2019 Sep;19(9):988-1000. doi: 10.1016/S1473-3099(19)30163-X. Epub 2019 Aug 6. Erratum in: Lancet Infect Dis. 2020 Jan;20(1):e1.


NO-to-[N2O2]2--to-N2O Conversion Triggered by {Fe(NO)2}10-{Fe(NO)2}9 Dinuclear Dinitrosyl Iron Complex.

Wu WY, Hsu CN, Hsieh CH, Chiou TW, Tsai ML, Chiang MH, Liaw WF.

Inorg Chem. 2019 Aug 5;58(15):9586-9591. doi: 10.1021/acs.inorgchem.9b01635. Epub 2019 Jul 11.


Comparative study on baseline clinical characteristics of Asian versus non-Asian patients with paroxysmal nocturnal hemoglobinuria.

Sakurai M, Jang JH, Chou WC, Kim JS, Wilson A, Nishimura JI, Chiou TJ, Kanakura Y, Lee JW, Okamoto S.

Int J Hematol. 2019 Oct;110(4):411-418. doi: 10.1007/s12185-019-02699-7. Epub 2019 Jul 5.


Longitudinal Changes of PAI-1, MMP-2, and VEGF in Peritoneal Effluents and Their Associations with Peritoneal Small-Solute Transfer Rate in New Peritoneal Dialysis Patients.

Hao N, Chiou TT, Wu CH, Lei YY, Liang PL, Chao MC, Yang H, Chen JB.

Biomed Res Int. 2019 May 5;2019:2152584. doi: 10.1155/2019/2152584. eCollection 2019.


Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors.

Chen YS, Chiu YH, Li YS, Lin EY, Hsieh DK, Lee CH, Huang MH, Chuang HM, Lin SZ, Harn HJ, Chiou TW.

Int J Nanomedicine. 2019 May 16;14:3601-3613. doi: 10.2147/IJN.S193617. eCollection 2019.


Remote transplantation of human adipose-derived stem cells induces regression of cardiac hypertrophy by regulating the macrophage polarization in spontaneously hypertensive rats.

Lee TM, Harn HJ, Chiou TW, Chuang MH, Chen CH, Chuang CH, Lin PC, Lin SZ.

Redox Biol. 2019 Oct;27:101170. doi: 10.1016/j.redox.2019.101170. Epub 2019 Mar 21.


Structural and functional characterization of β2 -glycoprotein I domain 1 in anti-melanoma cell migration.

Leu SJ, Lee TY, Cheng SW, Tsai MY, Lin YS, Chiou TJ, Huang KY, Chiang AN.

Cancer Sci. 2019 Jun;110(6):1974-1986. doi: 10.1111/cas.14030. Epub 2019 May 15.


Comparison of Solute Clearance, Hospitalization Rate, and Aortic Arch Calcification between Online Hemodiafiltration and High-Flux Hemodialysis: A 6-Year Observational Study.

Hao N, Yang CH, Yang HT, Wu CH, Lei YY, Wu YP, Lin WT, Chiou TT, Chen JB.

Kidney Blood Press Res. 2019;44(2):264-276. doi: 10.1159/000499645. Epub 2019 Apr 5.


Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability.

Chiou TT, Long P, Schumann-Gillett A, Kanamarlapudi V, Haas SA, Harvey K, O'Mara ML, De Blas AL, Kalscheuer VM, Harvey RJ.

Front Mol Neurosci. 2019 Mar 12;12:60. doi: 10.3389/fnmol.2019.00060. eCollection 2019.


Cerebrovascular disease after allogeneic hematopoietic stem cell transplantation: incidence, risk, and clinical outcome.

Lin TA, Gau JP, Liu YC, Ko PS, Wang HY, Chien SH, Liu CJ, Hsiao LT, Chiou TJ, Liu JH.

Int J Hematol. 2019 May;109(5):584-592. doi: 10.1007/s12185-019-02624-y. Epub 2019 Mar 12.


A Cetuximab-Mediated Suicide System in Chimeric Antigen Receptor-Modified Hematopoietic Stem Cells for Cancer Therapy.

Kao RL, Truscott LC, Chiou TT, Tsai W, Wu AM, De Oliveira SN.

Hum Gene Ther. 2019 Apr;30(4):413-428. doi: 10.1089/hum.2018.180.


The impact on outcomes by using thiotepa in tandem transplant for pediatric high-risk embryonal brain tumors.

Yen HJ, Yu TY, Lee CY, Hung GY, Chiou TJ, Chen HH, Lee YY, Liang ML, Chen YW.

J Chin Med Assoc. 2019 Feb;82(2):148-154. doi: 10.1097/JCMA.0000000000000018.


Polarisation signals: a new currency for communication.

Marshall NJ, Powell SB, Cronin TW, Caldwell RL, Johnsen S, Gruev V, Chiou TS, Roberts NW, How MJ.

J Exp Biol. 2019 Feb 7;222(Pt 3). pii: jeb134213. doi: 10.1242/jeb.134213. Review.


Preconditioned adipose-derived stem cells ameliorate cardiac fibrosis by regulating macrophage polarization in infarcted rat hearts through the PI3K/STAT3 pathway.

Lee TM, Harn HJ, Chiou TW, Chuang MH, Chen CH, Chuang CH, Lin PC, Lin SZ.

Lab Invest. 2019 May;99(5):634-647. doi: 10.1038/s41374-018-0181-x. Epub 2019 Jan 25.


Long-term safety and efficacy of deferasirox in patients with myelodysplastic syndrome, aplastic anemia and other rare anemia in Taiwan.

Ko BS, Chang MC, Chiou TJ, Chang TK, Chen YC, Lin SF, Chang CS, Lu YC, Yeh SP, Chen TY, Hwang WS.

Hematology. 2019 Dec;24(1):247-254. doi: 10.1080/16078454.2018.1557860.


A nationwide survey of adherence to analgesic drugs among cancer patients in Taiwan: prevalence, determinants, and impact on quality of life.

Chou WC, Chen JS, Hung CY, Lu CH, Shao YY, Chiou TJ, Sung YC, Rau KM, Yen CJ, Yeh SP, Liu TC, Wu MF, Lee MY, Yu MS, Hwang WL, Lai PY, Chang CS, Hsieh RK.

Support Care Cancer. 2019 Aug;27(8):2857-2867. doi: 10.1007/s00520-018-4599-x. Epub 2018 Dec 14.


Hematopoietic stem cell transplantation for subcutaneous panniculitis-like T-cell lymphoma: single center experience in an Asian population.

Lin TA, Yang CF, Liu YC, Liu JH, Chiou TJ, Hsiao LT, Yen HJ, Liu CJ, Wang HY, Ko PS, Chien SH, Gau JP.

Int J Hematol. 2019 Feb;109(2):187-196. doi: 10.1007/s12185-018-02568-9. Epub 2018 Dec 13.


Draft Genome Sequence of Lactobacillus kosoi NBRC 113063, Isolated from Kôso, a Japanese Sugar-Vegetable Fermented Beverage.

Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T.

Microbiol Resour Announc. 2018 Nov 21;7(20). pii: e01173-18. doi: 10.1128/MRA.01173-18. eCollection 2018 Nov.


Oxidative Stress and Nonalcoholic Fatty Liver Disease in Hemodialysis Patients.

Wu PJ, Chen JB, Lee WC, Ng HY, Lien SC, Tsai PY, Wu CH, Lee CT, Chiou TT.

Biomed Res Int. 2018 Nov 1;2018:3961748. doi: 10.1155/2018/3961748. eCollection 2018.


The Number of Comorbidities Predicts Renal Outcomes in Patients with Stage 3⁻5 Chronic Kidney Disease.

Lee WC, Lee YT, Li LC, Ng HY, Kuo WH, Lin PT, Liao YC, Chiou TT, Lee CT.

J Clin Med. 2018 Nov 28;7(12). pii: E493. doi: 10.3390/jcm7120493.


Epigenetic targeting DNMT1 of pancreatic ductal adenocarcinoma using interstitial control release biodegrading polymer reduced tumor growth through hedgehog pathway inhibition.

Huang MH, Chou YW, Li MH, Shih TE, Lin SZ, Chuang HM, Chiou TW, Su HL, Harn HJ.

Pharmacol Res. 2019 Jan;139:50-61. doi: 10.1016/j.phrs.2018.10.015. Epub 2018 Oct 29.


Satisfaction with pain management and impact of pain on quality of life in cancer patients.

Lin J, Hsieh RK, Chen JS, Lee KD, Rau KM, Shao YY, Sung YC, Yeh SP, Chang CS, Liu TC, Wu MF, Lee MY, Yu MS, Yen CJ, Lai PY, Hwang WL, Chiou TJ.

Asia Pac J Clin Oncol. 2020 Apr;16(2):e91-e98. doi: 10.1111/ajco.13095. Epub 2018 Oct 17.


Invasive mold infections in acute leukemia patients undergoing allogeneic hematopoietic stem cell transplantation.

Chien SH, Liu YC, Liu CJ, Ko PS, Wang HY, Hsiao LT, Chiou TJ, Liu JH, Gau JP.

J Microbiol Immunol Infect. 2019 Dec;52(6):973-982. doi: 10.1016/j.jmii.2018.09.006. Epub 2018 Sep 26.


Non-Canonical Regulation of Type I Collagen through Promoter Binding of SOX2 and Its Contribution to Ameliorating Pulmonary Fibrosis by Butylidenephthalide.

Chuang HM, Ho LI, Huang MH, Huang KL, Chiou TW, Lin SZ, Su HL, Harn HJ.

Int J Mol Sci. 2018 Oct 4;19(10). pii: E3024. doi: 10.3390/ijms19103024.


Patients with head and neck cancer may need more intensive pain management to maintain daily functioning: a multi-center study.

Cho SF, Rau KM, Shao YY, Yen CJ, Wu MF, Chen JS, Chang CS, Yeh SP, Chiou TJ, Hsieh RK, Lee MY, Sung YC, Lee KD, Lai PY, Yu MS, Hwang WL, Liu TC.

Support Care Cancer. 2019 May;27(5):1663-1672. doi: 10.1007/s00520-018-4404-x. Epub 2018 Aug 15.


Early achievement of full donor chimerism after allogeneic hematopoietic stem cell transplantation predicts lower relapse risk in patients with acute lymphoblastic leukemia.

Chen CT, Gau JP, Liu JH, Chiou TJ, Hsiao LT, Liu YC.

J Chin Med Assoc. 2018 Dec;81(12):1038-1043. doi: 10.1016/j.jcma.2018.06.005. Epub 2018 Aug 9.


Mycobacterial infections in adult recipients of allogeneic hematopoietic stem cell transplantation: A cohort study in a high endemic area.

Liu YC, Wu CJ, Ko PS, Chien SH, Fan NW, Wang HY, Gau JP, Liu CJ, Hsiao LT, Chiou TJ, Liu CY, Liu JH.

J Microbiol Immunol Infect. 2018 Jul 26. pii: S1684-1182(18)30269-X. doi: 10.1016/j.jmii.2018.07.001. [Epub ahead of print]


Sensing and Signaling of Phosphate Starvation: From Local to Long Distance.

Chien PS, Chiang CP, Leong SJ, Chiou TJ.

Plant Cell Physiol. 2018 Sep 1;59(9):1714-1722. doi: 10.1093/pcp/pcy148.


Advances in Patient-Specific Induced Pluripotent Stem Cells Shed Light on Drug Discovery for Amyotrophic Lateral Sclerosis.

Lee JH, Liu JW, Lin SZ, Harn HJ, Chiou TW.

Cell Transplant. 2018 Sep;27(9):1301-1312. doi: 10.1177/0963689718785154. Epub 2018 Jul 23. Review.


Primary bone marrow lymphoma: A hematological emergency in adults with fever of unknown origin.

Wang HY, Yang CF, Chiou TJ, Gau JP, Chen PM, Tsai CY, Hsu HC, Wang FD, Liu JH, Hsiao LT.

Cancer Med. 2018 Aug;7(8):3713-3721. doi: 10.1002/cam4.1669. Epub 2018 Jul 9.


Induced Pluripotent Stem Cells: A Powerful Neurodegenerative Disease Modeling Tool for Mechanism Study and Drug Discovery.

Chang CY, Ting HC, Liu CA, Su HL, Chiou TW, Harn HJ, Lin SZ.

Cell Transplant. 2018 Jan 1:963689718775406. doi: 10.1177/0963689718775406. [Epub ahead of print]


Arabidopsis inositol phosphate kinases IPK1 and ITPK1 constitute a metabolic pathway in maintaining phosphate homeostasis.

Kuo HF, Hsu YY, Lin WC, Chen KY, Munnik T, Brearley CA, Chiou TJ.

Plant J. 2018 May 19. doi: 10.1111/tpj.13974. [Epub ahead of print]

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