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Comprehensive T cell repertoire characterization of non-small cell lung cancer.

Reuben A, Zhang J, Chiou SH, Gittelman RM, Li J, Lee WC, Fujimoto J, Behrens C, Liu X, Wang F, Quek K, Wang C, Kheradmand F, Chen R, Chow CW, Lin H, Bernatchez C, Jalali A, Hu X, Wu CJ, Eterovic AK, Parra ER, Yusko E, Emerson R, Benzeno S, Vignali M, Wu X, Ye Y, Little LD, Gumbs C, Mao X, Song X, Tippen S, Thornton RL, Cascone T, Snyder A, Wargo JA, Herbst R, Swisher S, Kadara H, Moran C, Kalhor N, Zhang J, Scheet P, Vaporciyan AA, Sepesi B, Gibbons DL, Robins H, Hwu P, Heymach JV, Sharma P, Allison JP, Baladandayuthapani V, Lee JJ, Davis MM, Wistuba II, Futreal PA, Zhang J.

Nat Commun. 2020 Jan 30;11(1):603. doi: 10.1038/s41467-019-14273-0.


Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls.

Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, Davis MM, Stern LJ, Mellins ED.

Nat Commun. 2020 Jan 8;11(1):242. doi: 10.1038/s41467-019-13776-0.


PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.

Wang LT, Liu KY, Jeng WY, Chiang CM, Chai CY, Chiou SS, Huang MS, Yokoyama KK, Wang SN, Huang SK, Hsu SH.

EMBO Rep. 2020 Feb 5;21(2):e48795. doi: 10.15252/embr.201948795. Epub 2020 Jan 7.


Musashi-1 promotes stress-induced tumor progression through recruitment of AGO2.

Chen HY, Wang ML, Laurent B, Hsu CH, Chen MT, Lin LT, Shen J, Chang WC, Hsu J, Hung MC, Chen YW, Huang PI, Yang YP, Li CP, Ma HI, Chen CH, Lin WC, Chiou SH.

Theranostics. 2020 Jan 1;10(1):201-217. doi: 10.7150/thno.35895. eCollection 2020.


ROC-guided survival trees and ensembles.

Sun Y, Chiou SH, Wang MC.

Biometrics. 2019 Dec 27. doi: 10.1111/biom.13213. [Epub ahead of print]


In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls.

Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, Davis MM, Stern LJ, Mellins ED.

Nat Commun. 2019 Nov 20;10(1):5247. doi: 10.1038/s41467-019-13234-x. Erratum in: Nat Commun. 2020 Jan 8;11(1):242.


Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies.

Sung YC, Jin PR, Chu LA, Hsu FF, Wang MR, Chang CC, Chiou SJ, Qiu JT, Gao DY, Lin CC, Chen YS, Hsu YC, Wang J, Wang FN, Yu PL, Chiang AS, Wu AY, Ko JJ, Lai CP, Lu TT, Chen Y.

Nat Nanotechnol. 2019 Dec;14(12):1160-1169. doi: 10.1038/s41565-019-0570-3. Epub 2019 Nov 18.


Carboxylated nanodiamond-mediated CRISPR-Cas9 delivery of human retinoschisis mutation into human iPSCs and mouse retina.

Yang TC, Chang CY, Yarmishyn AA, Mao YS, Yang YP, Wang ML, Hsu CC, Yang HY, Hwang DK, Chen SJ, Tsai ML, Lai YH, Tzeng Y, Chang CC, Chiou SH.

Acta Biomater. 2020 Jan 1;101:484-494. doi: 10.1016/j.actbio.2019.10.037. Epub 2019 Oct 28.


Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis.

Huang KC, Wang ML, Chen SJ, Kuo JC, Wang WJ, Nhi Nguyen PN, Wahlin KJ, Lu JF, Tran AA, Shi M, Chien Y, Yarmishyn AA, Tsai PH, Yang TC, Jane WN, Chang CC, Peng CH, Schlaeger TM, Chiou SH.

Stem Cell Reports. 2019 Nov 12;13(5):906-923. doi: 10.1016/j.stemcr.2019.09.010. Epub 2019 Oct 24.


GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease.

Ko HJ, Chiou SJ, Wong YH, Wang YH, Lai Y, Chou CH, Wang C, Loh JK, Lieu AS, Cheng JT, Lin YT, Lu PJ, Fann MJ, Huang CF, Hong YR.

J Clin Med. 2019 Oct 21;8(10). pii: E1751. doi: 10.3390/jcm8101751.


The missing indicator approach for censored covariates subject to limit of detection in logistic regression models.

Chiou SH, Betensky RA, Balasubramanian R.

Ann Epidemiol. 2019 Oct;38:57-64. doi: 10.1016/j.annepidem.2019.07.014. Epub 2019 Aug 13.


Induced Pluripotent Stem Cells Attenuate Endothelial Leakage in Acute Lung Injury via Tissue Inhibitor of Metalloproteinases-1 to Reduce Focal Adhesion Kinase Activity.

Su VY, Chiou SH, Lin CS, Mo MH, Yang KY.

Stem Cells. 2019 Dec;37(12):1516-1527. doi: 10.1002/stem.3093. Epub 2019 Nov 18.


Effects of Facial Threading on Female Skin Texture: A Prospective Trial with Physiological Parameters and Sense Assessment.

Lin LY, Chiou SC, Wang SH, Chi CC.

Evid Based Complement Alternat Med. 2019 Aug 28;2019:1535713. doi: 10.1155/2019/1535713. eCollection 2019.


Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network.

Tsai PH, Chien Y, Wang ML, Hsu CH, Laurent B, Chou SJ, Chang WC, Chien CS, Li HY, Lee HC, Huo TI, Hung JH, Chen CH, Chiou SH.

Nucleic Acids Res. 2019 Nov 4;47(19):10115-10133. doi: 10.1093/nar/gkz801.


Modulation of osmotic stress-induced TRPV1 expression rescues human iPSC-derived retinal ganglion cells through PKA.

Hsu CC, Chien KH, Yarmishyn AA, Buddhakosai W, Wu WJ, Lin TC, Chiou SH, Chen JT, Peng CH, Hwang DK, Chen SJ, Chang YL.

Stem Cell Res Ther. 2019 Sep 23;10(1):284. doi: 10.1186/s13287-019-1363-1.


Nonidentifiability in the presence of factorization for truncated data.

Vakulenko-Lagun B, Qian J, Chiou SH, Betensky RA.

Biometrika. 2019 Sep;106(3):724-731. doi: 10.1093/biomet/asz023. Epub 2019 May 13.


Better Self-report Health Status and Provider-Patient Communication in Dental Service Can Improve the Patient Experience: A Cross-year Comparison from the NHI Survey.

Chiou SJ, Lee LH, Lee PC, Lin KC.

Health Commun. 2019 Aug 19:1-7. doi: 10.1080/10410236.2019.1652390. [Epub ahead of print]


NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts.

Fan YC, Liang JJ, Chen JM, Lin JW, Chen YY, Su KH, Lin CC, Tu WC, Chiou MT, Ou SC, Chang GJ, Lin YL, Chiou SS.

PLoS Pathog. 2019 Aug 5;15(8):e1007992. doi: 10.1371/journal.ppat.1007992. eCollection 2019 Aug.


Nanomedicine-based Curcumin Approach Improved ROS Damage in Best Dystrophy-specific Induced Pluripotent Stem Cells.

Lin TC, Lin YY, Hsu CC, Yang YP, Yang CH, Hwang DK, Wang CY, Liu YY, Lo WL, Chiou SH, Peng CH, Chen SJ, Chang YL.

Cell Transplant. 2019 Nov;28(11):1345-1357. doi: 10.1177/0963689719860130. Epub 2019 Jul 17.


Effect of cold provocation on vessel density in eyes with primary open angle glaucoma: An optical coherence tomography angiography study.

Chou WY, Liu CJ, Chen MJ, Chiou SH, Chen WT, Ko YC.

Sci Rep. 2019 Jun 28;9(1):9384. doi: 10.1038/s41598-019-45386-7.


Polyhistidine facilitates direct membrane translocation of cell-penetrating peptides into cells.

Lee HJ, Huang YW, Chiou SH, Aronstam RS.

Sci Rep. 2019 Jun 28;9(1):9398. doi: 10.1038/s41598-019-45830-8.


Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells.

Yang YP, Nguyen PNN, Lin TC, Yarmishyn AA, Chen WS, Hwang DK, Chiou GY, Lin TW, Chien CS, Tsai CY, Chiou SH, Chen SJ, Peng CH, Hsu CC.

Cells. 2019 Jun 21;8(6). pii: E625. doi: 10.3390/cells8060625.


Dual Delivery of HNF4α and Cisplatin by Mesoporous Silica Nanoparticles Inhibits Cancer Pluripotency and Tumorigenicity in Hepatoma-Derived CD133-Expressing Stem Cells.

Tsai PH, Wang ML, Chang JH, Yarmishyn AA, Nhi Nguyen PN, Chen W, Chien Y, Huo TI, Mou CY, Chiou SH.

ACS Appl Mater Interfaces. 2019 Jun 5;11(22):19808-19818. doi: 10.1021/acsami.9b04474. Epub 2019 May 16.


Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging.

Syu JP, Buddhakosai W, Chen SJ, Ke CC, Chiou SH, Kuo WC.

Biomed Opt Express. 2018 Nov 12;9(12):6132-6144. doi: 10.1364/BOE.9.006132. eCollection 2018 Dec 1.


Superior Effects of Modified Chen-Style Tai Chi versus 24-Style Tai Chi on Cognitive Function, Fitness, and Balance Performance in Adults over 55.

Zou L, Loprinzi PD, Yu JJ, Yang L, Li C, Yeung AS, Kong Z, Chiou SY, Xiao T.

Brain Sci. 2019 May 4;9(5). pii: E102. doi: 10.3390/brainsci9050102.


Generation of GLA-Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy.

Song HY, Chien CS, Yarmishyn AA, Chou SJ, Yang YP, Wang ML, Wang CY, Leu HB, Yu WC, Chang YL, Chiou SH.

Cells. 2019 Apr 8;8(4). pii: E327. doi: 10.3390/cells8040327.


A cross-sectional follow-up study of physical morbidities, neurocognitive function, and attention problems in post-treatment childhood acute lymphoblastic leukemia survivors.

Chiou SS, Lin PC, Liao YM, Yang P.

Kaohsiung J Med Sci. 2019 Jun;35(6):373-378. doi: 10.1002/kjm2.12061. Epub 2019 Mar 26.


The longitudinal study for the work-related factors to job performance among nurses in emergency department.

Chen FL, Chen KC, Chiou SY, Chen PY, Du ML, Tung TH.

Medicine (Baltimore). 2019 Mar;98(12):e14950. doi: 10.1097/MD.0000000000014950.


Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer.

Dong J, Zhang RY, Sun N, Smalley M, Wu Z, Zhou A, Chou SJ, Jan YJ, Yang P, Bao L, Qi D, Tang X, Tseng P, Hua Y, Xu D, Kao R, Meng M, Zheng X, Liu Y, Vagner T, Chai X, Zhou D, Li M, Chiou SH, Zheng G, Di Vizio D, Agopian VG, Posadas E, Jonas SJ, Ju SP, Weiss PS, Zhao M, Tseng HR, Zhu Y.

ACS Appl Mater Interfaces. 2019 Apr 17;11(15):13973-13983. doi: 10.1021/acsami.9b01406. Epub 2019 Apr 2.


Combination Therapy of Chloroquine and C₂-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells.

Chou HL, Lin YH, Liu W, Wu CY, Li RN, Huang HW, Chou CH, Chiou SJ, Chiu CC.

Cancers (Basel). 2019 Mar 15;11(3). pii: E370. doi: 10.3390/cancers11030370.


Curcumin and tetrahydrocurcumin induce cell death in Ara-C-resistant acute myeloid leukemia.

Tseng YH, Chiou SS, Weng JP, Lin PC.

Phytother Res. 2019 Apr;33(4):1199-1207. doi: 10.1002/ptr.6316. Epub 2019 Mar 5.


Corrigendum to "Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis" [Stem Cell Res. 29(2018): 152-156].

Peng CH, Huang KC, Lu HE, Syu SH, Yarmishyn AA, Lu JF, Buddhakosai W, Lin TC, Hsu CC, Hwang DK, Shen CN, Chen SJ, Chiou SH.

Stem Cell Res. 2019 Jan;34:101388. doi: 10.1016/j.scr.2019.101388. No abstract available.


Correction: Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma.

Wang LT, Chiou SS, Chai CY, Hsi E, Wang SN, Huang SK, Hsu SH.

Oncotarget. 2018 Dec 28;9(102):37807. doi: 10.18632/oncotarget.26547. eCollection 2018 Dec 28.


Using a Text Mining Approach to Explore the Recording Quality of a Nursing Record System.

Chang HM, Huang EW, Hou IC, Liu HY, Li FS, Chiou SF.

J Nurs Res. 2019 Jun;27(3):e27. doi: 10.1097/jnr.0000000000000295.


Induced Pluripotent Stem Cells Regulate Triggering Receptor Expressed on Myeloid Cell-1 Expression and the p38 Mitogen-Activated Protein Kinase Pathway in Endotoxin-Induced Acute Lung Injury.

Su VY, Yang KY, Chiou SH, Chen NJ, Mo MH, Lin CS, Wang CT.

Stem Cells. 2019 May;37(5):631-639. doi: 10.1002/stem.2980. Epub 2019 Feb 16.


Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells.

Chu CW, Ko HJ, Chou CH, Cheng TS, Cheng HW, Liang YH, Lai YL, Lin CY, Wang C, Loh JK, Cheng JT, Chiou SJ, Su CL, Huang CF, Hong YR.

Int J Mol Sci. 2019 Jan 22;20(3). pii: E473. doi: 10.3390/ijms20030473.


Artificial intelligence-based decision-making for age-related macular degeneration.

Hwang DK, Hsu CC, Chang KJ, Chao D, Sun CH, Jheng YC, Yarmishyn AA, Wu JC, Tsai CY, Wang ML, Peng CH, Chien KH, Kao CL, Lin TC, Woung LC, Chen SJ, Chiou SH.

Theranostics. 2019 Jan 1;9(1):232-245. doi: 10.7150/thno.28447. eCollection 2019.


Permutation Tests for General Dependent Truncation.

Chiou SH, Qian J, Mormino E, Betensky RA; Alzheimer’s Disease Neuroimaging Initiative; Australian Imaging Biomarkers Lifestyle Flagship Study of Aging; Harvard Aging Brain Study.

Comput Stat Data Anal. 2018 Dec;128:308-324. doi: 10.1016/j.csda.2018.07.012. Epub 2018 Jul 29.


A WHO-HPH operational program versus usual routines for implementing clinical health promotion: an RCT in health promoting hospitals (HPH).

Svane JK, Chiou ST, Groene O, Kalvachova M, Brkić MZ, Fukuba I, Härm T, Farkas J, Ang Y, Andersen MØ, Tønnesen H.

Implement Sci. 2018 Dec 22;13(1):153. doi: 10.1186/s13012-018-0848-0.


Organoid Modeling of the Tumor Immune Microenvironment.

Neal JT, Li X, Zhu J, Giangarra V, Grzeskowiak CL, Ju J, Liu IH, Chiou SH, Salahudeen AA, Smith AR, Deutsch BC, Liao L, Zemek AJ, Zhao F, Karlsson K, Schultz LM, Metzner TJ, Nadauld LD, Tseng YY, Alkhairy S, Oh C, Keskula P, Mendoza-Villanueva D, De La Vega FM, Kunz PL, Liao JC, Leppert JT, Sunwoo JB, Sabatti C, Boehm JS, Hahn WC, Zheng GXY, Davis MM, Kuo CJ.

Cell. 2018 Dec 13;175(7):1972-1988.e16. doi: 10.1016/j.cell.2018.11.021.


Transformation model estimation of survival under dependent truncation and independent censoring.

Chiou SH, Austin MD, Qian J, Betensky RA.

Stat Methods Med Res. 2019 Dec;28(12):3785-3798. doi: 10.1177/0962280218817573. Epub 2018 Dec 13.


The Efficacy of Concurrent or Sequential Intravenous and Intratympanic Steroid for Idiopathic Sudden Sensorineural Hearing Loss.

Chu CH, Chiou SR, Wang MC, Shiao AS, Tu TY, Lin LY, Huang CY, Liao WH.

Audiol Neurootol. 2018;23(5):277-284. doi: 10.1159/000494966. Epub 2018 Dec 11.


Effectiveness of a no-cost-to-workers, slip-resistant footwear program for reducing slipping-related injuries in food service workers: a cluster randomized trial.

Bell JL, Collins JW, Chiou S.

Scand J Work Environ Health. 2019 Mar 1;45(2):194-202. doi: 10.5271/sjweh.3790. Epub 2018 Dec 6.


Assessment of the effects of walking as an exercise intervention for children and adolescents with cancer: A feasibility study.

Su HL, Wu LM, Chiou SS, Lin PC, Liao YM.

Eur J Oncol Nurs. 2018 Dec;37:29-34. doi: 10.1016/j.ejon.2018.10.006. Epub 2018 Oct 19.


Noninfectious uveitis in the Asia-Pacific region.

Hsu YR, Huang JC, Tao Y, Kaburaki T, Lee CS, Lin TC, Hsu CC, Chiou SH, Hwang DK.

Eye (Lond). 2019 Jan;33(1):66-77. doi: 10.1038/s41433-018-0223-z. Epub 2018 Oct 15. Review.


Whole-exome sequencing for the genetic diagnosis of congenital red blood cell membrane disorders in Taiwan.

Lin PC, Chiou SS, Lin CY, Wang SC, Huang HY, Chang YS, Tseng YH, Kan TM, Liao YM, Tsai SP, Peng CT, Chang JG.

Clin Chim Acta. 2018 Dec;487:311-317. doi: 10.1016/j.cca.2018.10.020. Epub 2018 Oct 11.


Treatment of childhood acute lymphoblastic leukemia with delayed first intrathecal therapy and omission of prophylactic cranial irradiation: Results of the TPOG-ALL-2002 study.

Yeh TC, Liang DC, Hou JY, Jaing TH, Lin DT, Yang CP, Peng CT, Hung IJ, Lin KH, Hsiao CC, Jou ST, Chiou SS, Chen JS, Wang SC, Chang TK, Wu KH, Sheen JM, Yen HJ, Chen SH, Lu MY, Li MJ, Chang TT, Huang TH, Chang YH, Chen SH, Yang YL, Chang HH, Chen BW, Lin PC, Cheng CN, Chao YH, Yang SH, Chao YY, Liu HC.

Cancer. 2018 Dec 1;124(23):4538-4547. doi: 10.1002/cncr.31758. Epub 2018 Oct 10.


Clinical Features and Genotypes of Patients with Hemoglobin H Disease in Taiwan.

Lin PC, Chang TT, Liao YM, Tsai SP, Chen YC, Hsu WY, Su HL, Zeng YS, Tseng YH, Chiou SS.

Lab Med. 2019 Apr 8;50(2):168-173. doi: 10.1093/labmed/lmy043.


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