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Items: 1 to 50 of 145

1.

Identification of RNA aptamer which specifically interacts with PtdIns(3)P.

Donia T, Jyoti B, Suizu F, Hirata N, Tanaka T, Ishigaki S, F PTJ, Nio-Kobayashi J, Iwanaga T, Chiorini JA, Noguchi M.

Biochem Biophys Res Commun. 2019 Sep 10;517(1):146-154. doi: 10.1016/j.bbrc.2019.07.034. Epub 2019 Jul 24.

2.

Profiling Autoantibodies against Salivary Proteins in Sicca Conditions.

Burbelo PD, Ferré EMN, Chaturvedi A, Chiorini JA, Alevizos I, Lionakis MS, Warner BM.

J Dent Res. 2019 Jul;98(7):772-778. doi: 10.1177/0022034519850564. Epub 2019 May 16.

PMID:
31095438
3.

Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment.

Vivino FB, Bunya VY, Massaro-Giordano G, Johr CR, Giattino SL, Schorpion A, Shafer B, Peck A, Sivils K, Rasmussen A, Chiorini JA, He J, Ambrus JL Jr.

Clin Immunol. 2019 Jun;203:81-121. doi: 10.1016/j.clim.2019.04.009. Epub 2019 Apr 29. Review. No abstract available.

PMID:
31022578
4.

ICTV Virus Taxonomy Profile: Parvoviridae.

Cotmore SF, Agbandje-McKenna M, Canuti M, Chiorini JA, Eis-Hubinger AM, Hughes J, Mietzsch M, Modha S, Ogliastro M, Pénzes JJ, Pintel DJ, Qiu J, Soderlund-Venermo M, Tattersall P, Tijssen P, Ictv Report Consortium.

J Gen Virol. 2019 Mar;100(3):367-368. doi: 10.1099/jgv.0.001212. Epub 2019 Jan 23.

5.

Correction to: ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference.

Pranzatelli TJF, Michae DG, Chiorini JA.

BMC Genomics. 2019 Jan 15;20(1):44. doi: 10.1186/s12864-019-5441-7.

6.

Targeting primary Sjögren's syndrome.

Odani T, Chiorini JA.

Mod Rheumatol. 2019 Jan;29(1):70-86. doi: 10.1080/14397595.2018.1546268. Review.

PMID:
30424703
7.

Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation.

Michael DG, Pranzatelli TJF, Warner BM, Yin H, Chiorini JA.

J Dent Res. 2019 Feb;98(2):209-217. doi: 10.1177/0022034518806518. Epub 2018 Nov 4.

PMID:
30392435
8.

ATAC2GRN: optimized ATAC-seq and DNase1-seq pipelines for rapid and accurate genome regulatory network inference.

Pranzatelli TJF, Michael DG, Chiorini JA.

BMC Genomics. 2018 Jul 31;19(1):563. doi: 10.1186/s12864-018-4943-z. Erratum in: BMC Genomics. 2019 Jan 15;20(1):44.

9.

Cross-contamination of the human salivary gland HSG cell line with HeLa cells: A STR analysis study.

Lin LC, Elkashty O, Ramamoorthi M, Trinh N, Liu Y, Sunavala-Dossabhoy G, Pranzatelli T, Michael DG, Chivasso C, Perret J, Chiorini JA, Delporte C, Tran SD.

Oral Dis. 2018 Nov;24(8):1477-1483. doi: 10.1111/odi.12920. Epub 2018 Jul 10.

PMID:
29923277
10.

Gene-edited pseudogene resurrection corrects p47phox-deficient chronic granulomatous disease.

Merling RK, Kuhns DB, Sweeney CL, Wu X, Burkett S, Chu J, Lee J, Koontz S, Di Pasquale G, Afione SA, Chiorini JA, Kang EM, Choi U, De Ravin SS, Malech HL.

Blood Adv. 2016 Dec 28;1(4):270-278. doi: 10.1182/bloodadvances.2016001214. eCollection 2017 Jan 10.

11.

In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors.

Crispino G, Galindo Ramirez F, Campioni M, Zorzi V, Praetorius M, Di Pasquale G, Chiorini JA, Mammano F.

Sci Rep. 2017 Aug 4;7(1):6567. doi: 10.1038/s41598-017-06759-y.

12.

Restoration of CFTR Activity in Ducts Rescues Acinar Cell Function and Reduces Inflammation in Pancreatic and Salivary Glands of Mice.

Zeng M, Szymczak M, Ahuja M, Zheng C, Yin H, Swaim W, Chiorini JA, Bridges RJ, Muallem S.

Gastroenterology. 2017 Oct;153(4):1148-1159. doi: 10.1053/j.gastro.2017.06.011. Epub 2017 Jun 19.

13.

Neutralizing antibodies against adeno-associated viruses in Sjögren's patients: implications for gene therapy.

Corden A, Handelman B, Yin H, Cotrim A, Alevizos I, Chiorini JA.

Gene Ther. 2017 Apr;24(4):241-244. doi: 10.1038/gt.2017.1. Epub 2017 Feb 2.

14.

Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction.

Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Billings ME, Goldsmith CM, Tandon M, Helmerhorst EJ, Catalán MA, Danielides SJ, Perez P, Nikolov NP, Chiorini JA, Melvin JE, Oppenheim FG, Illei GG, Baum BJ.

Gene Ther. 2017 Mar;24(3):176-186. doi: 10.1038/gt.2016.87. Epub 2016 Dec 20.

15.

Computational modeling of epithelial fluid and ion transport in the parotid duct after transfection of human aquaporin-1.

Fong S, Chiorini JA, Sneyd J, Suresh V.

Am J Physiol Gastrointest Liver Physiol. 2017 Feb 1;312(2):G153-G163. doi: 10.1152/ajpgi.00374.2016. Epub 2016 Dec 8.

16.

Gene Therapy of Salivary Diseases.

Baum BJ, Afione S, Chiorini JA, Cotrim AP, Goldsmith CM, Zheng C.

Methods Mol Biol. 2017;1537:107-123.

17.

Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.

Alevizos I, Zheng C, Cotrim AP, Goldsmith CM, McCullagh L, Berkowitz T, Strobl SL, Malyguine A, Kopp WC, Chiorini JA, Nikolov NP, Neely M, Illei GG, Baum BJ.

Oral Dis. 2017 Apr;23(3):337-346. doi: 10.1111/odi.12614. Epub 2017 Feb 8.

18.

Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo.

Weller ML, Gardener MR, Bogus ZC, Smith MA, Astorri E, Michael DG, Michael DA, Zheng C, Burbelo PD, Lai Z, Wilson PA, Swaim W, Handelman B, Afione SA, Bombardieri M, Chiorini JA.

Pathog Immun. 2016 May;1(1):12-40.

19.

Aquaporin gene therapy corrects Sjögren's syndrome phenotype in mice.

Lai Z, Yin H, Cabrera-Pérez J, Guimaro MC, Afione S, Michael DG, Glenton P, Patel A, Swaim WD, Zheng C, Nguyen CQ, Nyberg F, Chiorini JA.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5694-9. doi: 10.1073/pnas.1601992113. Epub 2016 May 2.

20.

Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry.

Rhein BA, Brouillette RB, Schaack GA, Chiorini JA, Maury W.

J Virol. 2016 Jun 10;90(13):6097-6111. doi: 10.1128/JVI.00100-16. Print 2016 Jul 1.

21.

And one to bind them all.

Chiorini JA.

Oral Dis. 2016 Nov;22(8):716-718. doi: 10.1111/odi.12495. Epub 2016 Jun 29. No abstract available.

PMID:
27109444
22.

Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases.

Gan L, O'Hanlon TP, Lai Z, Fannin R, Weller ML, Rider LG, Chiorini JA, Miller FW.

PLoS One. 2015 Nov 10;10(11):e0142486. doi: 10.1371/journal.pone.0142486. eCollection 2015.

23.

Advances in salivary gland gene therapy - oral and systemic implications.

Baum BJ, Alevizos I, Chiorini JA, Cotrim AP, Zheng C.

Expert Opin Biol Ther. 2015;15(10):1443-54. doi: 10.1517/14712598.2015.1064894. Epub 2015 Jul 6. Review.

24.

Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity.

Tseng YS, Gurda BL, Chipman P, McKenna R, Afione S, Chiorini JA, Muzyczka N, Olson NH, Baker TS, Kleinschmidt J, Agbandje-McKenna M.

J Virol. 2015 Feb;89(3):1794-808. doi: 10.1128/JVI.02710-14. Epub 2014 Nov 19.

25.

Identification and mutagenesis of the adeno-associated virus 5 sialic acid binding region.

Afione S, DiMattia MA, Halder S, Di Pasquale G, Agbandje-McKenna M, Chiorini JA.

J Virol. 2015 Feb;89(3):1660-72. doi: 10.1128/JVI.02503-14. Epub 2014 Nov 19.

26.

Glycosylation, hypogammaglobulinemia, and resistance to viral infections.

Sadat MA, Moir S, Chun TW, Lusso P, Kaplan G, Wolfe L, Memoli MJ, He M, Vega H, Kim LJY, Huang Y, Hussein N, Nievas E, Mitchell R, Garofalo M, Louie A, Ireland DC, Grunes C, Cimbro R, Patel V, Holzapfel G, Salahuddin D, Bristol T, Adams D, Marciano BE, Hegde M, Li Y, Calvo KR, Stoddard J, Justement JS, Jacques J, Priel DAL, Murray D, Sun P, Kuhns DB, Boerkoel CF, Chiorini JA, Di Pasquale G, Verthelyi D, Rosenzweig SD.

N Engl J Med. 2014 Apr 24;370(17):1615-1625. doi: 10.1056/NEJMoa1302846. Epub 2014 Apr 9.

27.

Toxicity and biodistribution of the serotype 2 recombinant adeno-associated viral vector, encoding Aquaporin-1, after retroductal delivery to a single mouse parotid gland.

Momot D, Zheng C, Yin H, Elbekai RH, Vallant M, Chiorini JA.

PLoS One. 2014 Mar 25;9(3):e92832. doi: 10.1371/journal.pone.0092832. eCollection 2014.

28.

Matriptase deletion initiates a Sjögren's syndrome-like disease in mice.

Yin H, Kosa P, Liu X, Swaim WD, Lai Z, Cabrera-Perez J, Di Pasquale G, Ambudkar IS, Bugge TH, Chiorini JA.

PLoS One. 2014 Feb 13;9(2):e82852. doi: 10.1371/journal.pone.0082852. eCollection 2014. Erratum in: PLoS One. 2014;9(5):e98331.

29.

Targeting the splicing of mRNA in autoimmune diseases: BAFF inhibition in Sjögren's syndrome as a proof of concept.

Roescher N, Vosters JL, Alsaleh G, Dreyfus P, Jacques S, Chiocchia G, Sibilia J, Tak PP, Chiorini JA, Mariette X, Gottenberg JE.

Mol Ther. 2014 Apr;22(4):821-7. doi: 10.1038/mt.2013.275. Epub 2013 Dec 5.

30.

The family Parvoviridae.

Cotmore SF, Agbandje-McKenna M, Chiorini JA, Mukha DV, Pintel DJ, Qiu J, Soderlund-Venermo M, Tattersall P, Tijssen P, Gatherer D, Davison AJ.

Arch Virol. 2014 May;159(5):1239-47. doi: 10.1007/s00705-013-1914-1. Epub 2013 Nov 9.

31.

Association of bone morphogenetic protein 6 with exocrine gland dysfunction in patients with Sjögren's syndrome and in mice.

Yin H, Cabrera-Perez J, Lai Z, Michael D, Weller M, Swaim WD, Liu X, Catalán MA, Rocha EM, Ismail N, Afione S, Rana NA, Di Pasquale G, Alevizos I, Ambudkar I, Illei GG, Chiorini JA.

Arthritis Rheum. 2013 Dec;65(12):3228-38. doi: 10.1002/art.38123.

32.

Structural insights into adeno-associated virus serotype 5.

Govindasamy L, DiMattia MA, Gurda BL, Halder S, McKenna R, Chiorini JA, Muzyczka N, Zolotukhin S, Agbandje-McKenna M.

J Virol. 2013 Oct;87(20):11187-99. doi: 10.1128/JVI.00867-13. Epub 2013 Aug 7.

33.

Capsid antibodies to different adeno-associated virus serotypes bind common regions.

Gurda BL, DiMattia MA, Miller EB, Bennett A, McKenna R, Weichert WS, Nelson CD, Chen WJ, Muzyczka N, Olson NH, Sinkovits RS, Chiorini JA, Zolotutkhin S, Kozyreva OG, Samulski RJ, Baker TS, Parrish CR, Agbandje-McKenna M.

J Virol. 2013 Aug;87(16):9111-24. doi: 10.1128/JVI.00622-13. Epub 2013 Jun 12.

34.

Recovery of radiation-induced dry eye and corneal damage by pretreatment with adenoviral vector-mediated transfer of erythropoietin to the salivary glands in mice.

Rocha EM, Cotrim AP, Zheng C, Riveros PP, Baum BJ, Chiorini JA.

Hum Gene Ther. 2013 Apr;24(4):417-23. doi: 10.1089/hum.2012.111.

35.

Local administration of soluble CD40:Fc to the salivary glands of non-obese diabetic mice does not ameliorate autoimmune inflammation.

Roescher N, Vosters JL, Lai Z, Uede T, Tak PP, Chiorini JA.

PLoS One. 2012;7(12):e51375. doi: 10.1371/journal.pone.0051375. Epub 2012 Dec 26.

36.

Oral vaccination with adeno-associated virus vectors expressing the Neu oncogene inhibits the growth of murine breast cancer.

Steel JC, Di Pasquale G, Ramlogan CA, Patel V, Chiorini JA, Morris JC.

Mol Ther. 2013 Mar;21(3):680-7. doi: 10.1038/mt.2012.260. Epub 2013 Jan 8.

37.

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.

Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19403-7. doi: 10.1073/pnas.1210662109. Epub 2012 Nov 5.

38.

Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy.

Lee BH, Carcamo WC, Chiorini JA, Peck AB, Nguyen CQ.

Arthritis Res Ther. 2012 Jul 24;14(4):R172. doi: 10.1186/ar3925.

39.

Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes.

Di Pasquale G, Dicembrini I, Raimondi L, Pagano C, Egan JM, Cozzi A, Cinci L, Loreto A, Manni ME, Berretti S, Morelli A, Zheng C, Michael DG, Maggi M, Vettor R, Chiorini JA, Mannucci E, Rotella CM.

PLoS One. 2012;7(7):e40074. doi: 10.1371/journal.pone.0040074. Epub 2012 Jul 13.

40.

Mutation in the platelet-derived growth factor receptor alpha inhibits adeno-associated virus type 5 transduction.

Pilz IH, Di Pasquale G, Rzadzinska A, Leppla SH, Chiorini JA.

Virology. 2012 Jun 20;428(1):58-63. doi: 10.1016/j.virol.2012.03.004. Epub 2012 Apr 20.

41.

Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome.

Yin H, Nguyen CQ, Samuni Y, Uede T, Peck AB, Chiorini JA.

Arthritis Res Ther. 2012 Feb 27;14(1):R40. doi: 10.1186/ar3753.

42.

TACI-Fc gene therapy improves autoimmune sialadenitis but not salivary gland function in non-obese diabetic mice.

Vosters JL, Roescher N, Illei GG, Chiorini JA, Tak PP.

Oral Dis. 2012 May;18(4):365-74. doi: 10.1111/j.1601-0825.2011.01885.x. Epub 2011 Dec 29.

43.

Transduction, tropism, and biodistribution of AAV vectors in the lacrimal gland.

Rocha EM, Di Pasquale G, Riveros PP, Quinn K, Handelman B, Chiorini JA.

Invest Ophthalmol Vis Sci. 2011 Dec 20;52(13):9567-72. doi: 10.1167/iovs.11-8171.

44.

Viral gene transfer to developing mouse salivary glands.

Hsu JC, Di Pasquale G, Harunaga JS, Onodera T, Hoffman MP, Chiorini JA, Yamada KM.

J Dent Res. 2012 Feb;91(2):197-202. doi: 10.1177/0022034511429346. Epub 2011 Nov 17.

45.

Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5.

Harbison CE, Weichert WS, Gurda BL, Chiorini JA, Agbandje-McKenna M, Parrish CR.

J Gen Virol. 2012 Feb;93(Pt 2):347-55. doi: 10.1099/vir.0.035113-0. Epub 2011 Nov 9.

46.

Bovine AAV transcytosis inhibition by tannic acid results in functional expression of CFTR in vitro and altered biodistribution in vivo.

Di Pasquale G, Ostedgaard L, Vermeer D, Swaim WD, Karp P, Chiorini JA.

Gene Ther. 2012 May;19(5):576-81. doi: 10.1038/gt.2011.138. Epub 2011 Oct 20.

47.

Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjögren's syndrome.

Roescher N, Lodde BM, Vosters JL, Tak PP, Catalan MA, Illei GG, Chiorini JA.

Oral Dis. 2012 Jan;18(1):96-106. doi: 10.1111/j.1601-0825.2011.01852.x. Epub 2011 Sep 14.

48.

BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.

Crispino G, Di Pasquale G, Scimemi P, Rodriguez L, Galindo Ramirez F, De Siati RD, Santarelli RM, Arslan E, Bortolozzi M, Chiorini JA, Mammano F.

PLoS One. 2011;6(8):e23279. doi: 10.1371/journal.pone.0023279. Epub 2011 Aug 18.

49.

Intranasal administration of adeno-associated virus type 12 (AAV12) leads to transduction of the nasal epithelia and can initiate transgene-specific immune response.

Quinn K, Quirion MR, Lo CY, Misplon JA, Epstein SL, Chiorini JA.

Mol Ther. 2011 Nov;19(11):1990-8. doi: 10.1038/mt.2011.146. Epub 2011 Aug 9.

50.

Microarray analysis of sexually dimorphic gene expression in human minor salivary glands.

Michael D, Soi S, Cabera-Perez J, Weller M, Alexander S, Alevizos I, Illei G, Chiorini J.

Oral Dis. 2011 Oct;17(7):653-61. doi: 10.1111/j.1601-0825.2011.01816.x. Epub 2011 Aug 8.

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