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Items: 50

1.

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.

Majorini MT, Manenti G, Mano M, De Cecco L, Conti A, Pinciroli P, Fontanella E, Tagliabue E, Chiodoni C, Colombo MP, Delia D, Lecis D.

Cell Death Differ. 2018 Apr 19. doi: 10.1038/s41418-018-0100-0. [Epub ahead of print]

PMID:
29674627
2.

Cross-Talk between Myeloid-Derived Suppressor Cells and Mast Cells Mediates Tumor-Specific Immunosuppression in Prostate Cancer.

Jachetti E, Cancila V, Rigoni A, Bongiovanni L, Cappetti B, Belmonte B, Enriquez C, Casalini P, Ostano P, Frossi B, Sangaletti S, Chiodoni C, Chiorino G, Pucillo CE, Tripodo C, Colombo MP.

Cancer Immunol Res. 2018 May;6(5):552-565. doi: 10.1158/2326-6066.CIR-17-0385. Epub 2018 Mar 9.

PMID:
29523597
3.

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy.

Di Martino MT, Zazzeroni F, Donadelli M, Chiodoni C, Caraglia M, Scotlandi K, Meschini S, Leonetti C.

J Exp Clin Cancer Res. 2018 Mar 5;37(1):48. doi: 10.1186/s13046-018-0710-x. No abstract available.

4.

The good and bad of targeting cancer-associated extracellular matrix.

Sangaletti S, Chiodoni C, Tripodo C, Colombo MP.

Curr Opin Pharmacol. 2017 Aug;35:75-82. doi: 10.1016/j.coph.2017.06.003. Epub 2017 Jul 19. Review.

PMID:
28734136
5.

Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors.

Ratti C, Botti L, Cancila V, Galvan S, Torselli I, Garofalo C, Manara MC, Bongiovanni L, Valenti CF, Burocchi A, Parenza M, Cappetti B, Sangaletti S, Tripodo C, Scotlandi K, Colombo MP, Chiodoni C.

Clin Cancer Res. 2017 Sep 1;23(17):5149-5161. doi: 10.1158/1078-0432.CCR-16-3186. Epub 2017 Jun 9.

PMID:
28600479
6.

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling.

Tripodo C, Burocchi A, Piccaluga PP, Chiodoni C, Portararo P, Cappetti B, Botti L, Gulino A, Isidori A, Liso A, Visani G, Martelli MP, Falini B, Pandolfi PP, Colombo MP, Sangaletti S.

Cancer Res. 2017 Jul 1;77(13):3685-3699. doi: 10.1158/0008-5472.CAN-17-1098. Epub 2017 May 23.

7.

Common extracellular matrix regulation of myeloid cell activity in the bone marrow and tumor microenvironments.

Sangaletti S, Chiodoni C, Tripodo C, Colombo MP.

Cancer Immunol Immunother. 2017 Aug;66(8):1059-1067. doi: 10.1007/s00262-017-2014-y. Epub 2017 May 13. Review.

PMID:
28501940
8.

Matricellular proteins tune myeloid-derived suppressor cell recruitment and function in breast cancer.

Chiodoni C, Sangaletti S, Colombo MP.

J Leukoc Biol. 2017 Aug;102(2):287-292. doi: 10.1189/jlb.3MR1016-447R. Epub 2017 Feb 1. Review.

PMID:
28148719
9.

Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.

Jachetti E, Rigoni A, Bongiovanni L, Arioli I, Botti L, Parenza M, Cancila V, Chiodoni C, Festinese F, Bellone M, Tardanico R, Tripodo C, Colombo MP.

Mol Cancer Ther. 2017 Feb;16(2):365-375. doi: 10.1158/1535-7163.MCT-16-0466. Epub 2016 Dec 15.

10.

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity.

Sangaletti S, Tripodo C, Santangelo A, Castioni N, Portararo P, Gulino A, Botti L, Parenza M, Cappetti B, Orlandi R, Tagliabue E, Chiodoni C, Colombo MP.

Cell Rep. 2016 Sep 27;17(1):233-248. doi: 10.1016/j.celrep.2016.08.075.

11.

Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.

Castagnoli L, Ghedini GC, Koschorke A, Triulzi T, Dugo M, Gasparini P, Casalini P, Palladini A, Iezzi M, Lamolinara A, Lollini PL, Nanni P, Chiodoni C, Tagliabue E, Pupa SM.

Oncogene. 2017 Mar 23;36(12):1721-1732. doi: 10.1038/onc.2016.338. Epub 2016 Sep 19.

12.

Healthy and tumoral tissue resistivity in wild-type and sparc-/- animal models.

Meroni D, Mauri G, Bovio D, Bianchi AM, Chiodoni C, Colombo MP, Meroni E, Aliverti A.

Med Biol Eng Comput. 2016 Dec;54(12):1949-1957. Epub 2016 Apr 21.

PMID:
27099155
13.

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site.

Rivoltini L, Chiodoni C, Squarcina P, Tortoreto M, Villa A, Vergani B, Bürdek M, Botti L, Arioli I, Cova A, Mauri G, Vergani E, Bianchi B, Della Mina P, Cantone L, Bollati V, Zaffaroni N, Gianni AM, Colombo MP, Huber V.

Clin Cancer Res. 2016 Jul 15;22(14):3499-512. doi: 10.1158/1078-0432.CCR-15-2170. Epub 2016 Mar 4.

14.

The ins and outs of osteopontin.

Chiodoni C, Sangaletti S, Tripodo C, Colombo MP.

Oncoimmunology. 2015 Apr 2;4(3):e978711. eCollection 2015 Mar.

15.

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias.

Vitali C, Bassani C, Chiodoni C, Fellini E, Guarnotta C, Miotti S, Sangaletti S, Fuligni F, De Cecco L, Piccaluga PP, Colombo MP, Tripodo C.

Cancer Res. 2015 Jun 1;75(11):2387-99. doi: 10.1158/0008-5472.CAN-14-3625. Epub 2015 Apr 9.

16.

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin.

Guerzoni C, Fiori V, Terracciano M, Manara MC, Moricoli D, Pasello M, Sciandra M, Nicoletti G, Gellini M, Dominici S, Chiodoni C, Fornasari PM, Lollini PL, Colombo MP, Picci P, Cianfriglia M, Magnani M, Scotlandi K.

Clin Cancer Res. 2015 Jan 1;21(1):146-56. doi: 10.1158/1078-0432.CCR-14-0492. Epub 2014 Dec 11.

17.

Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity.

Ferrari-Amorotti G, Chiodoni C, Shen F, Cattelani S, Soliera AR, Manzotti G, Grisendi G, Dominici M, Rivasi F, Colombo MP, Fatatis A, Calabretta B.

Neoplasia. 2014 Dec;16(12):1047-58. doi: 10.1016/j.neo.2014.10.006.

18.

Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.

Castagnoli L, Iezzi M, Ghedini GC, Ciravolo V, Marzano G, Lamolinara A, Zappasodi R, Gasparini P, Campiglio M, Amici A, Chiodoni C, Palladini A, Lollini PL, Triulzi T, Menard S, Nanni P, Tagliabue E, Pupa SM.

Cancer Res. 2014 Nov 1;74(21):6248-59. doi: 10.1158/0008-5472.CAN-14-0983. Epub 2014 Aug 27.

19.

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies.

Sangaletti S, Tripodo C, Portararo P, Dugo M, Vitali C, Botti L, Guarnotta C, Cappetti B, Gulino A, Torselli I, Casalini P, Chiodoni C, Colombo MP.

Oncoimmunology. 2014 Jun 5;3:e28989. eCollection 2014.

20.

Osteopontin shapes immunosuppression in the metastatic niche.

Sangaletti S, Tripodo C, Sandri S, Torselli I, Vitali C, Ratti C, Botti L, Burocchi A, Porcasi R, Tomirotti A, Colombo MP, Chiodoni C.

Cancer Res. 2014 Sep 1;74(17):4706-19. doi: 10.1158/0008-5472.CAN-13-3334. Epub 2014 Jul 17.

21.

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells.

Contaldo C, Myers TJ, Zucchini C, Manara MC, Chiodoni C, Colombo MP, Nicoletti G, Lollini PL, Li T, Longobardi L, Scotlandi K, Spagnoli A.

Growth Factors. 2014 Feb;32(1):41-52. doi: 10.3109/08977194.2013.870168. Epub 2014 Jan 20.

PMID:
24438070
22.

Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer.

Mauri G, Chiodoni C, Parenza M, Arioli I, Tripodo C, Colombo MP.

Cancer Immunol Immunother. 2013 Dec;62(12):1811-9. doi: 10.1007/s00262-013-1486-7. Epub 2013 Oct 18.

PMID:
24136641
23.

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.

Ferrari-Amorotti G, Fragliasso V, Esteki R, Prudente Z, Soliera AR, Cattelani S, Manzotti G, Grisendi G, Dominici M, Pieraccioli M, Raschellà G, Chiodoni C, Colombo MP, Calabretta B.

Cancer Res. 2013 Jan 1;73(1):235-45. doi: 10.1158/0008-5472.CAN-12-1739. Epub 2012 Oct 10.

24.

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion.

Tripodo C, Sangaletti S, Guarnotta C, Piccaluga PP, Cacciatore M, Giuliano M, Franco G, Chiodoni C, Sciandra M, Miotti S, Calvaruso G, Carè A, Florena AM, Scotlandi K, Orazi A, Pileri SA, Colombo MP.

Blood. 2012 Oct 25;120(17):3541-54. doi: 10.1182/blood-2011-12-398537. Epub 2012 Sep 5.

25.

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity.

Sangaletti S, Tripodo C, Chiodoni C, Guarnotta C, Cappetti B, Casalini P, Piconese S, Parenza M, Guiducci C, Vitali C, Colombo MP.

Blood. 2012 Oct 11;120(15):3007-18. doi: 10.1182/blood-2012-03-416156. Epub 2012 Aug 29.

26.

SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage.

Sangaletti S, Tripodo C, Cappetti B, Casalini P, Chiodoni C, Piconese S, Santangelo A, Parenza M, Arioli I, Miotti S, Colombo MP.

Am J Pathol. 2011 Dec;179(6):3000-10. doi: 10.1016/j.ajpath.2011.08.027. Epub 2011 Oct 11. Erratum in: Am J Pathol. 2012 Mar;180(3):1324.

27.

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses.

Piconese S, Costanza M, Tripodo C, Sangaletti S, Musio S, Pittoni P, Poliani PL, Burocchi A, Passafaro AL, Gorzanelli A, Vitali C, Chiodoni C, Barnaba V, Pedotti R, Colombo MP.

J Autoimmun. 2011 Dec;37(4):300-10. doi: 10.1016/j.jaut.2011.09.002. Epub 2011 Sep 29.

PMID:
21962567
28.

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis.

Sangaletti S, Tripodo C, Ratti C, Piconese S, Porcasi R, Salcedo R, Trinchieri G, Colombo MP, Chiodoni C.

Cancer Res. 2010 Oct 15;70(20):7764-75. doi: 10.1158/0008-5472.CAN-10-0471. Epub 2010 Oct 5.

29.

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis.

Chiodoni C, Colombo MP, Sangaletti S.

Cancer Metastasis Rev. 2010 Jun;29(2):295-307. doi: 10.1007/s10555-010-9221-8. Review.

PMID:
20386958
30.

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.

Sangaletti S, Di Carlo E, Gariboldi S, Miotti S, Cappetti B, Parenza M, Rumio C, Brekken RA, Chiodoni C, Colombo MP.

Cancer Res. 2008 Nov 1;68(21):9050-9. doi: 10.1158/0008-5472.CAN-08-1327.

31.

Triggering CD40 on endothelial cells contributes to tumor growth.

Chiodoni C, Iezzi M, Guiducci C, Sangaletti S, Alessandrini I, Ratti C, Tiboni F, Musiani P, Granger DN, Colombo MP.

J Exp Med. 2006 Oct 30;203(11):2441-50. Epub 2006 Oct 16.

32.

Interleukin-12 production by leukemia-derived dendritic cells counteracts the inhibitory effect of leukemic microenvironment on T cells.

Curti A, Pandolfi S, Aluigi M, Isidori A, Alessandrini I, Chiodoni C, Testoni N, Colombo MP, Baccarani M, Lemoli RM.

Exp Hematol. 2005 Dec;33(12):1521-30.

PMID:
16338495
33.

Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells.

Aluigi M, Fogli M, Curti A, Isidori A, Gruppioni E, Chiodoni C, Colombo MP, Versura P, D'Errico-Grigioni A, Ferri E, Baccarani M, Lemoli RM.

Stem Cells. 2006 Feb;24(2):454-61. Epub 2005 Aug 11.

34.

Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice.

Sangaletti S, Gioiosa L, Guiducci C, Rotta G, Rescigno M, Stoppacciaro A, Chiodoni C, Colombo MP.

J Cell Sci. 2005 Aug 15;118(Pt 16):3685-94. Epub 2005 Jul 26.

35.

Cancer immunotherapy based on killing of Salmonella-infected tumor cells.

Avogadri F, Martinoli C, Petrovska L, Chiodoni C, Transidico P, Bronte V, Longhi R, Colombo MP, Dougan G, Rescigno M.

Cancer Res. 2005 May 1;65(9):3920-7.

36.

A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication.

Xiang R, Mizutani N, Luo Y, Chiodoni C, Zhou H, Mizutani M, Ba Y, Becker JC, Reisfeld RA.

Cancer Res. 2005 Jan 15;65(2):553-61.

37.

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

Vicari AP, Vanbervliet B, Massacrier C, Chiodoni C, Vaure C, Aït-Yahia S, Dercamp C, Matsos F, Reynard O, Taverne C, Merle P, Colombo MP, O'Garra A, Trinchieri G, Caux C.

Novartis Found Symp. 2004;256:241-54; discussion 254-69. Review.

PMID:
15027495
38.
39.

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody.

Vicari AP, Chiodoni C, Vaure C, Aït-Yahia S, Dercamp C, Matsos F, Reynard O, Taverne C, Merle P, Colombo MP, O'Garra A, Trinchieri G, Caux C.

J Exp Med. 2002 Aug 19;196(4):541-9.

40.

Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-gamma: a role for intrinsic tumor immunogenicity and IL-15.

Gri G, Chiodoni C, Gallo E, Stoppacciaro A, Liew FY, Colombo MP.

Cancer Res. 2002 Aug 1;62(15):4390-7.

41.

IFN-gamma-independent synergistic effects of IL-12 and IL-15 induce anti-tumor immune responses in syngeneic mice.

Comes A, Di Carlo E, Musiani P, Rosso O, Meazza R, Chiodoni C, Colombo MP, Ferrini S.

Eur J Immunol. 2002 Jul;32(7):1914-23.

42.

Different requirements for alpha-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases.

Chiodoni C, Stoppacciaro A, Sangaletti S, Gri G, Cappetti B, Koezuka Y, Colombo MP.

Eur J Immunol. 2001 Oct;31(10):3101-10.

PMID:
11592087
44.

HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation.

Accornero P, Radrizzani M, Carè A, Mattia G, Chiodoni C, Kurrle R, Colombo MP.

FEBS Lett. 1998 Oct 9;436(3):461-5.

45.

Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing.

Rivoltini L, Radrizzani M, Accornero P, Squarcina P, Chiodoni C, Mazzocchi A, Castelli C, Tarsini P, Viggiano V, Belli F, Colombo MP, Parmiani G.

J Immunol. 1998 Aug 1;161(3):1220-30.

46.
47.

IL-1alpha gene-transfected human melanoma cells increase tumor-cell adhesion to endothelial cells and their retention in the lung of nude mice.

Chirivi RG, Chiodoni C, Musiani P, Garofalo A, Bernasconi S, Colombo MP, Giavazzi R.

Int J Cancer. 1996 Sep 17;67(6):856-63.

48.

Amount of interleukin 12 available at the tumor site is critical for tumor regression.

Colombo MP, Vagliani M, Spreafico F, Parenza M, Chiodoni C, Melani C, Stoppacciaro A.

Cancer Res. 1996 Jun 1;56(11):2531-4.

49.
50.

Cytokine gene transduction in tumor cells: interleukin (IL)-2 or IL-4 gene transfer in human melanoma cells.

Melani C, Chiodoni C, Arienti F, Maccalli C, Sule-Suso J, Anichini A, Colombo MP, Parmiani G.

Nat Immun. 1994 Mar-Jun;13(2-3):76-84.

PMID:
8173238

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