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Items: 1 to 50 of 64

1.

Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer.

Noberini R, Restellini C, Savoia EO, Raimondi F, Ghiani L, Jodice MG, Bertalot G, Bonizzi G, Capra M, Maffini FA, Tagliabue M, Ansarin M, Lupia M, Giordano M, Osti D, Pelicci G, Chiocca S, Bonaldi T.

Cancers (Basel). 2019 May 24;11(5). pii: E723. doi: 10.3390/cancers11050723.

2.

The role of the T-N tract in advanced stage tongue cancer.

Tagliabue M, Gandini S, Maffini F, Navach V, Bruschini R, Giugliano G, Lombardi F, Chiocca S, Rebecchi E, Sica E, Tommasino M, Calabrese L, Ansarin M.

Head Neck. 2019 Apr 3. doi: 10.1002/hed.25761. [Epub ahead of print]

PMID:
30942940
3.

Synergistic antitumour activity of HDAC inhibitor SAHA and EGFR inhibitor gefitinib in head and neck cancer: a key role for ΔNp63α.

Citro S, Bellini A, Miccolo C, Ghiani L, Carey TE, Chiocca S.

Br J Cancer. 2019 Mar;120(6):658-667. doi: 10.1038/s41416-019-0394-9. Epub 2019 Feb 15.

PMID:
30765872
4.

Human Papilloma Virus and Autophagy.

Mattoscio D, Medda A, Chiocca S.

Int J Mol Sci. 2018 Jun 15;19(6). pii: E1775. doi: 10.3390/ijms19061775. Review.

5.

Extensive and systematic rewiring of histone post-translational modifications in cancer model systems.

Noberini R, Osti D, Miccolo C, Richichi C, Lupia M, Corleone G, Hong SP, Colombo P, Pollo B, Fornasari L, Pruneri G, Magnani L, Cavallaro U, Chiocca S, Minucci S, Pelicci G, Bonaldi T.

Nucleic Acids Res. 2018 May 4;46(8):3817-3832. doi: 10.1093/nar/gky224.

6.

High-risk human papillomavirus in anal squamous cell carcinoma: a 'conservative' leading role.

Ravenda PS, Zampino MG, Guerini-Rocco E, Chiocca S, Dell'Acqua V, Trovato C, Biffi R, Ribero D, Spada F, Cella CA, Fazio N.

Ann Oncol. 2017 May 1;28(5):1160. doi: 10.1093/annonc/mdx032. No abstract available.

PMID:
28453691
7.

Role of EGFR as prognostic factor in head and neck cancer patients treated with surgery and postoperative radiotherapy: proposal of a new approach behind the EGFR overexpression.

Alterio D, Marvaso G, Maffini F, Gandini S, Chiocca S, Ferrari A, Preda L, Rocca MC, Lepanto D, Fodor C, Volpe S, Dicuonzo S, Laudati A, Giugliano G, Ansarin M, Jereczek-Fossa BA.

Med Oncol. 2017 Jun;34(6):107. doi: 10.1007/s12032-017-0965-7. Epub 2017 Apr 27.

PMID:
28452036
8.

Role of mucosal high-risk human papillomavirus types in head and neck cancers in central India.

Gheit T, Anantharaman D, Holzinger D, Alemany L, Tous S, Lucas E, Prabhu PR, Pawlita M, Ridder R, Rehm S, Bogers J, Maffini F, Chiocca S, Lloveras B, Kumar RV, Somanathan T, de Sanjosé S, Castellsagué X, Arbyn M, Brennan P, Sankaranarayanan R, Pillai MR, Gangane N, Tommasino M; HPV-AHEAD study group.

Int J Cancer. 2017 Jul 1;141(1):143-151. doi: 10.1002/ijc.30712. Epub 2017 Apr 19.

9.

Autophagy regulates UBC9 levels during viral-mediated tumorigenesis.

Mattoscio D, Casadio C, Miccolo C, Maffini F, Raimondi A, Tacchetti C, Gheit T, Tagliabue M, Galimberti VE, De Lorenzi F, Pawlita M, Chiesa F, Ansarin M, Tommasino M, Chiocca S.

PLoS Pathog. 2017 Mar 2;13(3):e1006262. doi: 10.1371/journal.ppat.1006262. eCollection 2017 Mar.

10.

Assessing the Role of Paralog-Specific Sumoylation of HDAC1.

Citro S, Chiocca S.

Methods Mol Biol. 2017;1510:329-337.

PMID:
27761832
11.

Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development.

Loponte S, Segré CV, Senese S, Miccolo C, Santaguida S, Deflorian G, Citro S, Mattoscio D, Pisati F, Moser MA, Visintin R, Seiser C, Chiocca S.

Sci Rep. 2016 Jul 26;6:30213. doi: 10.1038/srep30213.

12.

Detection of Sumo Modification of Endogenous Histone Deacetylase 2 (HDAC2) in Mammalian Cells.

Citro S, Chiocca S.

Methods Mol Biol. 2016;1436:15-22. doi: 10.1007/978-1-4939-3667-0_2.

PMID:
27246205
13.

Anal human papillomavirus infection: prevalence, diagnosis and treatment of related lesions.

Benevolo M, Donà MG, Ravenda PS, Chiocca S.

Expert Rev Anti Infect Ther. 2016;14(5):465-77. doi: 10.1586/14787210.2016.1174065. Review.

PMID:
27050294
14.

A monoclonal antibody specific for prophase phosphorylation of histone deacetylase 1: a readout for early mitotic cells.

Segré CV, Senese S, Loponte S, Santaguida S, Soffientini P, Grigorean G, Cinquanta M, Ossolengo G, Seiser C, Chiocca S.

MAbs. 2016;8(1):37-42. doi: 10.1080/19420862.2015.1098795. Epub 2015 Oct 14.

15.

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

Lovisa S, Citro S, Sonego M, Dall'Acqua A, Ranzuglia V, Berton S, Colombatti A, Belletti B, Chiocca S, Schiappacassi M, Baldassarre G.

J Mol Cell Biol. 2016 Feb;8(1):17-30. doi: 10.1093/jmcb/mjv056. Epub 2015 Oct 8.

16.

SUMO pathway components as possible cancer biomarkers.

Mattoscio D, Chiocca S.

Future Oncol. 2015;11(11):1599-610. doi: 10.2217/fon.15.41. Review.

PMID:
26043214
17.

The SUMO conjugating enzyme UBC9 as a biomarker for cervical HPV infections.

Mattoscio D, Casadio C, Fumagalli M, Sideri M, Chiocca S.

Ecancermedicalscience. 2015 Apr 29;9:534. doi: 10.3332/ecancer.2015.534. eCollection 2015.

18.

Human papillomavirus in anal squamous cell carcinoma: an angel rather than a devil?

Ravenda PS, Zampino MG, Fazio N, Barberis M, Bottiglieri L, Chiocca S.

Ecancermedicalscience. 2015 Apr 29;9:529. doi: 10.3332/ecancer.2015.529. eCollection 2015.

19.

Role of human papillomaviruses in carcinogenesis.

Ghittoni R, Accardi R, Chiocca S, Tommasino M.

Ecancermedicalscience. 2015 Apr 29;9:526. doi: 10.3332/ecancer.2015.526. eCollection 2015. Review.

20.

Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer.

Chiaradonna F, Barozzi I, Miccolo C, Bucci G, Palorini R, Fornasari L, Botrugno OA, Pruneri G, Masullo M, Passafaro A, Galimberti VE, Fantin VR, Richon VM, Pece S, Viale G, Di Fiore PP, Draetta G, Pelicci PG, Minucci S, Chiocca S.

Antioxid Redox Signal. 2015 Jul 1;23(1):15-29. doi: 10.1089/ars.2014.6189. Epub 2015 May 27.

21.

PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression.

Citro S, Miccolo C, Meloni L, Chiocca S.

J Mol Cell Biol. 2015 Apr;7(2):132-42. doi: 10.1093/jmcb/mjv021. Epub 2015 Mar 23.

PMID:
25801958
22.

HPV in oropharyngeal cancer: the basics to know in clinical practice.

Elrefaey S, Massaro MA, Chiocca S, Chiesa F, Ansarin M.

Acta Otorhinolaryngol Ital. 2014 Oct;34(5):299-309. Review.

23.

Expression and in vitro functional analyses of recombinant Gam1 protein.

Avila GA, Ramirez DH, Hildenbrand ZL, Jacquez P, Chiocca S, Sun J, Rosas-Acosta G, Xiao C.

Protein Expr Purif. 2015 Jan;105:47-53. doi: 10.1016/j.pep.2014.10.005. Epub 2014 Oct 16.

24.

The chicken adenovirus Gam1 protein, an inhibitor of the sumoylation pathway, partially complements ICP0-null mutant herpes simplex virus 1.

Everett RD, Chiocca S, Orr A.

J Virol. 2014 May;88(10):5873-6. doi: 10.1128/JVI.00080-14. Epub 2014 Mar 5.

25.

SUMO Ubc9 enzyme as a viral target.

Varadaraj A, Mattoscio D, Chiocca S.

IUBMB Life. 2014 Jan;66(1):27-33. doi: 10.1002/iub.1240. Epub 2014 Jan 6. Review.

26.

Viral manipulation of cellular protein conjugation pathways: The SUMO lesson.

Mattoscio D, Segré CV, Chiocca S.

World J Virol. 2013 May 12;2(2):79-90. doi: 10.5501/wjv.v2.i2.79. Review.

27.

BC-box protein domain-related mechanism for VHL protein degradation.

Pozzebon ME, Varadaraj A, Mattoscio D, Jaffray EG, Miccolo C, Galimberti V, Tommasino M, Hay RT, Chiocca S.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18168-73. doi: 10.1073/pnas.1311382110. Epub 2013 Oct 21.

28.

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.

Newbold A, Matthews GM, Bots M, Cluse LA, Clarke CJ, Banks KM, Cullinane C, Bolden JE, Christiansen AJ, Dickins RA, Miccolo C, Chiocca S, Kral AM, Ozerova ND, Miller TA, Methot JL, Richon VM, Secrist JP, Minucci S, Johnstone RW.

Mol Cancer Ther. 2013 Dec;12(12):2709-21. doi: 10.1158/1535-7163.MCT-13-0626. Epub 2013 Oct 3.

29.

A role for paralog-specific sumoylation in histone deacetylase 1 stability.

Citro S, Jaffray E, Hay RT, Seiser C, Chiocca S.

J Mol Cell Biol. 2013 Dec;5(6):416-27. doi: 10.1093/jmcb/mjt032. Epub 2013 Sep 25.

PMID:
24068740
30.

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.

Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S, Altucci L, Pelicci PG, Chiocca S, Johnstone RW, Minucci S.

Blood. 2013 Apr 25;121(17):3459-68. doi: 10.1182/blood-2012-10-461988. Epub 2013 Feb 25.

31.

Sumo paralogs: redundancy and divergencies.

Citro S, Chiocca S.

Front Biosci (Schol Ed). 2013 Jan 1;5:544-53. Review.

PMID:
23277067
32.

The human cytomegalovirus DNA polymerase processivity factor UL44 is modified by SUMO in a DNA-dependent manner.

Sinigalia E, Alvisi G, Segré CV, Mercorelli B, Muratore G, Winkler M, Hsiao HH, Urlaub H, Ripalti A, Chiocca S, Palù G, Loregian A.

PLoS One. 2012;7(11):e49630. doi: 10.1371/journal.pone.0049630. Epub 2012 Nov 15.

33.

Lifting the threshold between life and death: SUMO and HDAC fine-tune HIPK2 to sense redox status.

Chiocca S, Seiser C.

Mol Cell. 2012 May 25;46(4):382-3. doi: 10.1016/j.molcel.2012.05.010.

34.

Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2.

Segré CV, Chiocca S.

J Biomed Biotechnol. 2011;2011:690848. doi: 10.1155/2011/690848. Epub 2010 Dec 9. Review.

35.

A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors.

Simboeck E, Sawicka A, Zupkovitz G, Senese S, Winter S, Dequiedt F, Ogris E, Di Croce L, Chiocca S, Seiser C.

J Biol Chem. 2010 Dec 24;285(52):41062-73. doi: 10.1074/jbc.M110.184481. Epub 2010 Oct 14.

36.

Listeria monocytogenes: a bacterial pathogen to hit on the SUMO pathway.

Citro S, Chiocca S.

Cell Res. 2010 Jul;20(7):738-40. doi: 10.1038/cr.2010.76. Epub 2010 Jun 8. No abstract available.

PMID:
20531377
37.

The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.

Zupkovitz G, Grausenburger R, Brunmeir R, Senese S, Tischler J, Jurkin J, Rembold M, Meunier D, Egger G, Lagger S, Chiocca S, Propst F, Weitzer G, Seiser C.

Mol Cell Biol. 2010 Mar;30(5):1171-81. doi: 10.1128/MCB.01500-09. Epub 2009 Dec 22.

38.

Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells.

Fritah S, Col E, Boyault C, Govin J, Sadoul K, Chiocca S, Christians E, Khochbin S, Jolly C, Vourc'h C.

Mol Biol Cell. 2009 Dec;20(23):4976-84. doi: 10.1091/mbc.E09-04-0295. Epub 2009 Sep 30.

39.

Inhibition of the SUMO pathway by Gam1.

Pozzebon M, Segré CV, Chiocca S.

Methods Mol Biol. 2009;497:285-301. doi: 10.1007/978-1-59745-566-4_19. Review.

PMID:
19107425
40.

The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising EM, Boggio R, Chiocca S, Helin K, Pasini D.

PLoS One. 2008 Jul 16;3(7):e2704. doi: 10.1371/journal.pone.0002704.

41.

Nuclear ubiquitin ligases, NF-kappaB degradation, and the control of inflammation.

Natoli G, Chiocca S.

Sci Signal. 2008 Jan 8;1(1):pe1. doi: 10.1126/stke.11pe1. Review.

PMID:
18270169
42.

Viral control of the SUMO pathway: Gam1, a model system.

Chiocca S.

Biochem Soc Trans. 2007 Dec;35(Pt 6):1419-21. Review.

PMID:
18031235
43.

Gam1-associated alterations of drug responsiveness through activation of apoptosis.

Wu F, Chiocca S, Beck WT, Mo YY.

Mol Cancer Ther. 2007 Jun;6(6):1823-30.

44.

Role for histone deacetylase 1 in human tumor cell proliferation.

Senese S, Zaragoza K, Minardi S, Muradore I, Ronzoni S, Passafaro A, Bernard L, Draetta GF, Alcalay M, Seiser C, Chiocca S.

Mol Cell Biol. 2007 Jul;27(13):4784-95. Epub 2007 Apr 30.

45.

Targeting SUMO E1 to ubiquitin ligases: a viral strategy to counteract sumoylation.

Boggio R, Passafaro A, Chiocca S.

J Biol Chem. 2007 May 25;282(21):15376-82. Epub 2007 Mar 28.

46.

Autoimmune pancreatitis: a systemic immune complex mediated disease.

Deshpande V, Chicano S, Finkelberg D, Selig MK, Mino-Kenudson M, Brugge WR, Colvin RB, Lauwers GY.

Am J Surg Pathol. 2006 Dec;30(12):1537-45. Erratum in: Am J Surg Pathol. 2007 Feb;31(2):328. Chiocca, Sonia [corrected to Chicano, Sonia].

PMID:
17122509
47.

Negative and positive regulation of gene expression by mouse histone deacetylase 1.

Zupkovitz G, Tischler J, Posch M, Sadzak I, Ramsauer K, Egger G, Grausenburger R, Schweifer N, Chiocca S, Decker T, Seiser C.

Mol Cell Biol. 2006 Nov;26(21):7913-28. Epub 2006 Aug 28.

48.

Viruses and sumoylation: recent highlights.

Boggio R, Chiocca S.

Curr Opin Microbiol. 2006 Aug;9(4):430-6. Epub 2006 Jul 3. Review.

PMID:
16815735
49.

Sumoylation induced by the Arf tumor suppressor: a p53-independent function.

Tago K, Chiocca S, Sherr CJ.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7689-94. Epub 2005 May 16.

50.

Gam1 and the SUMO pathway.

Boggio R, Chiocca S.

Cell Cycle. 2005 Apr;4(4):533-5. Epub 2005 Apr 15. Review.

PMID:
15876861

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