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Items: 1 to 50 of 369

1.

Letter: When Less is More: Dexamethasone Dosing for Brain Tumors.

Lim-Fat MJ, Bi WL, Lo J, Lee EQ, Ahluwalia MS, Batchelor TT, Chang SM, Chiocca EA, Chukwueke U, Cloughesy TF, Colman H, Deangelis LM, Galanis E, Gilbert MR, De Groot JF, Lassman AB, Liau LM, Mason W, McFaline-Figueroa JR, Mehta MP, Mellinghoff IK, Nabors LB, Nayak L, Reardon DA, Wen PY.

Neurosurgery. 2019 Jun 19. pii: nyz186. doi: 10.1093/neuros/nyz186. [Epub ahead of print] No abstract available.

PMID:
31215634
2.

Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration.

Nowicki MO, Hayes JL, Chiocca EA, Lawler SE.

Cancers (Basel). 2019 Apr 3;11(4). pii: E466. doi: 10.3390/cancers11040466.

3.

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours.

Ricklefs FL, Maire CL, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland DH, Flitsch J, Martens T, Schmidt NO, Peine S, Breakefield XO, Lawler S, Chiocca EA, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K.

J Extracell Vesicles. 2019 Mar 21;8(1):1588555. doi: 10.1080/20013078.2019.1588555. eCollection 2019.

4.

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy.

Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA.

ACS Nano. 2019 Apr 23;13(4):4028-4040. doi: 10.1021/acsnano.8b08177. Epub 2019 Mar 27.

PMID:
30916923
5.

Frameless Stereotactic Navigation during Insular Glioma Resection using Fusion of Three-Dimensional Rotational Angiography and Magnetic Resonance Imaging: A Technical Note.

Dasenbrock HH, See AP, Smalley RJ, Bi WL, Dolati P, Frerichs KU, Golby AJ, Chiocca EA, Aziz-Sultan MA.

World Neurosurg. 2019 Mar 18. pii: S1878-8750(19)30764-8. doi: 10.1016/j.wneu.2019.03.096. [Epub ahead of print]

PMID:
30898738
6.

Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis.

Krenzlin H, Behera P, Lorenz V, Passaro C, Zdioruk M, Nowicki MO, Grauwet K, Zhang H, Skubal M, Ito H, Zane R, Gutknecht M, Griessl MB, Ricklefs F, Ding L, Peled S, Rooj A, James CD, Cobbs CS, Cook CH, Chiocca EA, Lawler SE.

J Clin Invest. 2019 Mar 11;130:1671-1683. doi: 10.1172/JCI123375. eCollection 2019 Mar 11.

7.

Molecular responses to immune checkpoint blockade in glioblastoma.

Ito H, Nakashima H, Chiocca EA.

Nat Med. 2019 Mar;25(3):359-361. doi: 10.1038/s41591-019-0385-7. No abstract available.

PMID:
30842671
8.

Pneumatosis intestinalis after molecular targeted therapy.

Chaudhry NS, Bi WL, Gupta S, Keraliya A, Shimizu N, Chiocca EA.

World Neurosurg. 2019 Feb 11. pii: S1878-8750(19)30337-7. doi: 10.1016/j.wneu.2019.01.225. [Epub ahead of print]

PMID:
30763745
9.

The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.

Bhaskaran V, Nowicki MO, Idriss M, Jimenez MA, Lugli G, Hayes JL, Mahmoud AB, Zane RE, Passaro C, Ligon KL, Haas-Kogan D, Bronisz A, Godlewski J, Lawler SE, Chiocca EA, Peruzzi P.

Nat Commun. 2019 Jan 25;10(1):442. doi: 10.1038/s41467-019-08390-z.

10.

Amendments: Publisher Correction: An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma.

Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai H, Chiocca EA, Kaur B, Caligiuri MA, Yu J.

Nat Biotechnol. 2019 Jan 3;37(1):102. doi: 10.1038/nbt0119-102c. No abstract available.

PMID:
30605164
11.

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA.

Nature. 2019 Jan;565(7738):234-239. doi: 10.1038/s41586-018-0792-9. Epub 2018 Dec 19.

PMID:
30568305
12.

Characterization of single microvesicles in plasma from glioblastoma patients.

Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R.

Neuro Oncol. 2019 May 6;21(5):606-615. doi: 10.1093/neuonc/noy187.

PMID:
30561734
13.

An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma.

Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai H, Chiocca EA, Kaur B, Caligiuri MA, Yu J.

Nat Biotechnol. 2018 Nov 26. doi: 10.1038/nbt.4302. [Epub ahead of print]

14.

Viral and other therapies for recurrent glioblastoma: is a 24-month durable response unusual?

Chiocca EA, Nassiri F, Wang J, Peruzzi P, Zadeh G.

Neuro Oncol. 2019 Jan 1;21(1):14-25. doi: 10.1093/neuonc/noy170.

PMID:
30346600
15.

The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health.

Luo C, Yang Q, Liu Y, Zhou S, Jiang J, Reiter RJ, Bhattacharya P, Cui Y, Yang H, Ma H, Yao J, Lawler SE, Zhang X, Fu J, Rozental R, Aly H, Johnson MD, Chiocca EA, Wang X.

Free Radic Biol Med. 2019 Jan;130:215-233. doi: 10.1016/j.freeradbiomed.2018.10.402. Epub 2018 Oct 11. Review.

PMID:
30315933
16.

Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.

Passaro C, Alayo Q, De Laura I, McNulty J, Grauwet K, Ito H, Bhaskaran V, Mineo M, Lawler SE, Shah K, Speranza MC, Goins W, McLaughlin E, Fernandez S, Reardon DA, Freeman GJ, Chiocca EA, Nakashima H.

Clin Cancer Res. 2019 Jan 1;25(1):290-299. doi: 10.1158/1078-0432.CCR-18-2311. Epub 2018 Oct 2.

PMID:
30279232
17.

Immunotherapy for glioblastoma: going viral.

Iorgulescu JB, Reardon DA, Chiocca EA, Wu CJ.

Nat Med. 2018 Aug;24(8):1094-1096. doi: 10.1038/s41591-018-0142-3. No abstract available.

18.

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.

Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A.

Nat Commun. 2018 Aug 6;9(1):3116. doi: 10.1038/s41467-018-05036-4.

19.

Viruses in cancer therapy - from benchwarmers to quarterbacks.

Peruzzi P, Chiocca EA.

Nat Rev Clin Oncol. 2018 Nov;15(11):657-658. doi: 10.1038/s41571-018-0077-0. No abstract available.

PMID:
30057404
20.

Endoscopic Endonasal Resection of a Suprasellar Pituitary Adenoma Mimicking Tuberculum Sellae Meningioma in a Patient with an Intrasellar Persistent Trigeminal Artery.

Montaser AS, Todeschini AB, Revuelta Barbero JM, Shahein M, Chiocca EA, Otto BA, Carrau RL, Prevedello DM.

J Neurol Surg B Skull Base. 2018 Apr;79(Suppl 3):S285-S286. doi: 10.1055/s-0038-1625943. Epub 2018 Feb 14.

21.

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.

Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA.

Sci Adv. 2018 Mar 7;4(3):eaar2766. doi: 10.1126/sciadv.aar2766. eCollection 2018 Mar.

22.

Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.

Nakashima H, Nguyen T, Kasai K, Passaro C, Ito H, Goins WF, Shaikh I, Erdelyi R, Nishihara R, Nakano I, Reardon DA, Anderson AC, Kuchroo V, Chiocca EA.

Clin Cancer Res. 2018 Jun 1;24(11):2574-2584. doi: 10.1158/1078-0432.CCR-17-2954. Epub 2018 Mar 6.

23.

Adult Tethered Cord Syndrome Following Chiari Decompression.

Jackson C, Yang BW, Bi WL, Chiocca EA, Groff MW.

World Neurosurg. 2018 Apr;112:205-208. doi: 10.1016/j.wneu.2018.01.165. Epub 2018 Feb 1.

PMID:
29409774
24.

Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells.

Delaunay T, Violland M, Boisgerault N, Dutoit S, Vignard V, Münz C, Gannage M, Dréno B, Vaivode K, Pjanova D, Labarrière N, Wang Y, Chiocca EA, Boeuf FL, Bell JC, Erbs P, Tangy F, Grégoire M, Fonteneau JF.

Oncoimmunology. 2017 Dec 26;7(3):e1407897. doi: 10.1080/2162402X.2017.1407897. eCollection 2018.

25.

Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells.

Nakashima H, Alayo QA, Penaloza-MacMaster P, Freeman GJ, Kuchroo VK, Reardon DA, Fernandez S, Caligiuri M, Chiocca EA.

Sci Rep. 2018 Jan 9;8(1):208. doi: 10.1038/s41598-017-18540-2.

26.

Multiplexed Profiling of Single Extracellular Vesicles.

Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca EA, Breakefield XO, Lee H, Weissleder R.

ACS Nano. 2018 Jan 23;12(1):494-503. doi: 10.1021/acsnano.7b07060. Epub 2018 Jan 4.

27.

Immunotherapy for glioblastoma: on the sidelines or in the game?

Reardon DA, Wucherpfennig K, Chiocca EA.

Discov Med. 2017 Nov;24(133):201-208. Review.

28.

Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models.

Berger G, Grauwet K, Zhang H, Hussey AM, Nowicki MO, Wang DI, Chiocca EA, Lawler SE, Lippard SJ.

Cancer Lett. 2018 Mar 1;416:138-148. doi: 10.1016/j.canlet.2017.11.041. Epub 2017 Dec 13.

PMID:
29246647
29.

Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma.

Nandhu MS, Behera P, Bhaskaran V, Longo SL, Barrera-Arenas LM, Sengupta S, Rodriguez-Gil DJ, Chiocca EA, Viapiano MS.

Clin Cancer Res. 2018 Feb 15;24(4):821-833. doi: 10.1158/1078-0432.CCR-17-1628. Epub 2017 Nov 16.

30.

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.

Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen PY, Chiocca EA, Lawler SE.

Neuro Oncol. 2018 Jan 22;20(2):225-235. doi: 10.1093/neuonc/nox139.

31.

Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier.

Fadzen CM, Wolfe JM, Cho CF, Chiocca EA, Lawler SE, Pentelute BL.

J Am Chem Soc. 2017 Nov 8;139(44):15628-15631. doi: 10.1021/jacs.7b09790. Epub 2017 Oct 30.

32.

Salvage re-irradiation for recurrent high-grade glioma and comparison to bevacizumab alone.

Arvold ND, Shi DD, Aizer AA, Norden AD, Reardon DA, Lee EQ, Nayak L, Dunn IF, Golby AJ, Johnson MD, Claus EB, Chiocca EA, Ligon KL, Wen PY, Alexander BM.

J Neurooncol. 2017 Dec;135(3):581-591. doi: 10.1007/s11060-017-2611-9. Epub 2017 Oct 3.

PMID:
28975467
33.

The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.

Dai HS, Griffin N, Bolyard C, Mao HC, Zhang J, Cripe TP, Suenaga T, Arase H, Nakano I, Chiocca EA, Kaur B, Yu J, Caligiuri MA.

Immunity. 2017 Jul 18;47(1):159-170.e10. doi: 10.1016/j.immuni.2017.06.019.

34.

MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells.

Rooj AK, Ricklefs F, Mineo M, Nakano I, Chiocca EA, Bronisz A, Godlewski J.

Cell Rep. 2017 Jun 6;19(10):2026-2032. doi: 10.1016/j.celrep.2017.05.040.

35.

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.

Cho CF, Wolfe JM, Fadzen CM, Calligaris D, Hornburg K, Chiocca EA, Agar NYR, Pentelute BL, Lawler SE.

Nat Commun. 2017 Jun 6;8:15623. doi: 10.1038/ncomms15623.

36.

MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer.

Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A.

Stem Cell Reports. 2017 Jun 6;8(6):1497-1505. doi: 10.1016/j.stemcr.2017.04.024. Epub 2017 May 18.

37.

Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients.

Figueroa JM, Skog J, Akers J, Li H, Komotar R, Jensen R, Ringel F, Yang I, Kalkanis S, Thompson R, LoGuidice L, Berghoff E, Parsa A, Liau L, Curry W, Cahill D, Bettegowda C, Lang FF, Chiocca EA, Henson J, Kim R, Breakefield X, Chen C, Messer K, Hochberg F, Carter BS.

Neuro Oncol. 2017 Oct 19;19(11):1494-1502. doi: 10.1093/neuonc/nox085.

38.

Launching Effectiveness Research to Guide Practice in Neurosurgery: A National Institute Neurological Disorders and Stroke Workshop Report.

Walicke P, Abosch A, Asher A, Barker FG 2nd, Ghogawala Z, Harbaugh R, Jehi L, Kestle J, Koroshetz W, Little R, Rubin D, Valadka A, Wisniewski S, Chiocca EA; Workshop Participants.

Neurosurgery. 2017 Apr 1;80(4):505-514. doi: 10.1093/neuros/nyw133.

39.

Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models.

Teng J, Carla da Hora C, Kantar RS, Nakano I, Wakimoto H, Batchelor TT, Chiocca EA, Badr CE, Tannous BA.

Neuro Oncol. 2017 Jun 1;19(6):820-832. doi: 10.1093/neuonc/now253.

40.

Frontal dermoid cyst coexisting with suprasellar craniopharyngioma: a spectrum of ectodermally derived epithelial-lined cystic lesions?

Abou-Al-Shaar H, Abd-El-Barr MM, Zaidi HA, Russell-Goldman E, Folkerth RD, Laws ER Jr, Chiocca EA.

Neurosurg Focus. 2016 Dec;41(6):E16.

PMID:
27903118
41.

Glioma and microglia, a double entendre.

Grauwet K, Chiocca EA.

Nat Immunol. 2016 Oct 19;17(11):1240-1242. doi: 10.1038/ni.3586. No abstract available.

PMID:
27760107
42.

Association between shunt-responsive idiopathic normal pressure hydrocephalus and alcohol.

Hickman TT, Shuman ME, Johnson TA, Yang F, Rice RR, Rice IM, Chung EH, Wiemann R, Tinl M, Iracheta C, Chen G, Flynn P, Mondello MB, Thompson J, Meadows ME, Carroll RS, Yang HW, Xing H, Pilgrim D, Chiocca EA, Dunn IF, Golby AJ, Johnson MD.

J Neurosurg. 2017 Aug;127(2):240-248. doi: 10.3171/2016.6.JNS16496. Epub 2016 Sep 30.

PMID:
27689463
43.

Oncolytic Viruses in Cancer Treatment: A Review.

Lawler SE, Speranza MC, Cho CF, Chiocca EA.

JAMA Oncol. 2017 Jun 1;3(6):841-849. doi: 10.1001/jamaoncol.2016.2064. Review.

PMID:
27441411
44.

The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches.

Mineo M, Ricklefs F, Rooj AK, Lyons SM, Ivanov P, Ansari KI, Nakano I, Chiocca EA, Godlewski J, Bronisz A.

Cell Rep. 2016 Jun 14;15(11):2500-9. doi: 10.1016/j.celrep.2016.05.018. Epub 2016 Jun 2.

45.

Current State of Immune-Based Therapies for Glioblastoma.

Lim M, Weller M, Chiocca EA.

Am Soc Clin Oncol Educ Book. 2016;35:e132-9. doi: 10.14694/EDBK_159084. Review.

46.

Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.

Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE.

ACS Comb Sci. 2016 Jun 13;18(6):271-8. doi: 10.1021/acscombsci.5b00180. Epub 2016 May 23.

47.

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases.

Chen X, Han J, Chu J, Zhang L, Zhang J, Chen C, Chen L, Wang Y, Wang H, Yi L, Elder JB, Wang QE, He X, Kaur B, Chiocca EA, Yu J.

Oncotarget. 2016 May 10;7(19):27764-77. doi: 10.18632/oncotarget.8526.

48.

Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity.

Ricklefs F, Mineo M, Rooj AK, Nakano I, Charest A, Weissleder R, Breakefield XO, Chiocca EA, Godlewski J, Bronisz A.

Cancer Res. 2016 May 15;76(10):2876-81. doi: 10.1158/0008-5472.CAN-15-3432. Epub 2016 Mar 24.

49.

Human Cytomegalovirus is Present in Alveolar Soft Part Sarcoma.

Price RL, Harkins L, Chiocca EA, Zhang PJ, Kurt H, Iwenofu OH.

Appl Immunohistochem Mol Morphol. 2017 Oct;25(9):615-619. doi: 10.1097/PAI.0000000000000354.

PMID:
26990748
50.

Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors.

Bronisz A, Godlewski J, Chiocca EA.

Cell Mol Neurobiol. 2016 Apr;36(3):361-76. doi: 10.1007/s10571-015-0293-4. Epub 2016 Mar 17. Review.

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