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Items: 49

1.

Synthetic probe development for measuring single or few-cell activity and efflux.

Lui A, Wang J, Chio L, Landry MP.

Methods Enzymol. 2019;628:19-41. doi: 10.1016/bs.mie.2019.06.019. Epub 2019 Jul 9.

PMID:
31668229
2.

Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM.

Mol Cancer Ther. 2019 Dec;18(12):2207-2219. doi: 10.1158/1535-7163.MCT-18-0529. Epub 2019 Sep 17.

PMID:
31530649
3.

Advances in Nanomaterials for Brain Microscopy.

Del Bonis-O'Donnell JT, Chio L, Dorlhiac GF, McFarlane IR, Landry MP.

Nano Res. 2018 Oct;11(10):5144-5172. doi: 10.1007/s12274-018-2145-2. Epub 2018 Aug 8.

4.

Electrostatic Assemblies of Single-Walled Carbon Nanotubes and Sequence-Tunable Peptoid Polymers Detect a Lectin Protein and Its Target Sugars.

Chio L, Del Bonis-O'Donnell JT, Kline MA, Kim JH, McFarlane IR, Zuckermann RN, Landry MP.

Nano Lett. 2019 Nov 13;19(11):7563-7572. doi: 10.1021/acs.nanolett.8b04955. Epub 2019 Apr 19.

PMID:
30958010
5.

High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants.

Demirer GS, Zhang H, Matos JL, Goh NS, Cunningham FJ, Sung Y, Chang R, Aditham AJ, Chio L, Cho MJ, Staskawicz B, Landry MP.

Nat Nanotechnol. 2019 May;14(5):456-464. doi: 10.1038/s41565-019-0382-5. Epub 2019 Feb 25.

PMID:
30804481
6.

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.

Gong X, Du J, Parsons SH, Merzoug FF, Webster Y, Iversen PW, Chio LC, Van Horn RD, Lin X, Blosser W, Han B, Jin S, Yao S, Bian H, Ficklin C, Fan L, Kapoor A, Antonysamy S, Mc Nulty AM, Froning K, Manglicmot D, Pustilnik A, Weichert K, Wasserman SR, Dowless M, Marugán C, Baquero C, Lallena MJ, Eastman SW, Hui YH, Dieter MZ, Doman T, Chu S, Qian HR, Ye XS, Barda DA, Plowman GD, Reinhard C, Campbell RM, Henry JR, Buchanan SG.

Cancer Discov. 2019 Feb;9(2):248-263. doi: 10.1158/2159-8290.CD-18-0469. Epub 2018 Oct 29.

PMID:
30373917
7.

Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.

Gong X, Litchfield LM, Webster Y, Chio LC, Wong SS, Stewart TR, Dowless M, Dempsey J, Zeng Y, Torres R, Boehnke K, Mur C, Marugán C, Baquero C, Yu C, Bray SM, Wulur IH, Bi C, Chu S, Qian HR, Iversen PW, Merzoug FF, Ye XS, Reinhard C, De Dios A, Du J, Caldwell CW, Lallena MJ, Beckmann RP, Buchanan SG.

Cancer Cell. 2017 Dec 11;32(6):761-776.e6. doi: 10.1016/j.ccell.2017.11.006.

8.

Surface Engineering of Nanoparticles to Create Synthetic Antibodies.

Chio L, Yang D, Landry M.

Methods Mol Biol. 2017;1575:363-380. doi: 10.1007/978-1-4939-6857-2_23.

PMID:
28255893
9.

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes.

Del Bonis-O'Donnell JT, Beyene A, Chio L, Demirer G, Yang D, Landry MP.

J Vis Exp. 2017 Jan 10;(119). doi: 10.3791/55030.

10.

Single-molecule detection of protein efflux from microorganisms using fluorescent single-walled carbon nanotube sensor arrays.

Landry MP, Ando H, Chen AY, Cao J, Kottadiel VI, Chio L, Yang D, Dong J, Lu TK, Strano MS.

Nat Nanotechnol. 2017 May;12(4):368-377. doi: 10.1038/nnano.2016.284. Epub 2017 Jan 23.

11.

Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450.

McIntosh JA, Heel T, Buller AR, Chio L, Arnold FH.

J Am Chem Soc. 2015 Nov 4;137(43):13861-5. doi: 10.1021/jacs.5b07107. Epub 2015 Sep 23.

12.

Exceedingly Efficient Synthesis of (±)-Grandifloracin and Acylated Analogues.

Bergner M, Duquette DC, Chio L, Stoltz BM.

Org Lett. 2015 Jun 19;17(12):3008-10. doi: 10.1021/acs.orglett.5b01292. Epub 2015 Jun 10.

PMID:
26060887
13.

Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice.

Liao B, McCall E, Cox K, Lee CW, Huang S, Higgs RE, Chio LC, Zhen E, Hale JE, Jackson NK, Rutherford PG, Huang XD, Gifford-Moore D, Hui K, Duffin K, Gould KE, Rekhter M.

Biomark Insights. 2008 Mar 12;3:147-157.

14.

Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening.

Sussman A, Huss K, Chio LC, Heidler S, Shaw M, Ma D, Zhu G, Campbell RM, Park TS, Kulanthaivel P, Scott JE, Carpenter JW, Strege MA, Belvo MD, Swartling JR, Fischl A, Yeh WK, Shih C, Ye XS.

Eukaryot Cell. 2004 Aug;3(4):932-43.

15.

Induction of apoptosis by sphingoid long-chain bases in Aspergillus nidulans.

Cheng J, Park TS, Chio LC, Fischl AS, Ye XS.

Mol Cell Biol. 2003 Jan;23(1):163-77.

16.

Benefits of micronised Fenofibrate in type 2 diabetes mellitus subjects with good glycemic control.

Tan CE, Chew LS, Tai ES, Chio LF, Lim HS, Loh LM, Shepherd J.

Atherosclerosis. 2001 Feb 1;154(2):469-74.

PMID:
11166781
17.

Cardiovascular risk factors and LDL subfraction profile in Type 2 diabetes mellitus subjects with good glycaemic control.

Tan CE, Chew LS, Chio LF, Tai ES, Lim HS, Lim SC, Jayakumar L, Eng HK, Packard CJ.

Diabetes Res Clin Pract. 2001 Feb;51(2):107-14.

PMID:
11165690
18.

LY303366 exhibits rapid and potent fungicidal activity in flow cytometric assays of yeast viability.

Green LJ, Marder P, Mann LL, Chio LC, Current WL.

Antimicrob Agents Chemother. 1999 Apr;43(4):830-5.

19.
20.

Inborn errors of metabolism in Singapore.

Tan IK, Chio LF, Loh FC, Wee SC, Ng I, Teo SH, Yong YP, Chan D, Chow WC, Ho PS, et al.

J Inherit Metab Dis. 1995;18(3):341-6.

PMID:
7474902
21.

Urinary beta 2- and alpha 1-microglobulin levels in normal subjects in Singapore.

Gan SL, Chia SE, Chio LF, Chan OY, Kwok SF.

Occup Med (Lond). 1994 Sep;44(4):195-200.

PMID:
7524731
22.
23.

An unusual cause for cyanosis.

Mak KH, Tan AT, Jacob E, Chio LF.

Singapore Med J. 1993 Feb;34(1):83-4.

PMID:
8266139
24.

Urine microalbumin/creatinine ratios in Singapore children.

Yap C, Yap HK, Chio LF.

J Singapore Paediatr Soc. 1991;33(3-4):101-6.

PMID:
1812325
25.

Adenosine deaminase in pleural fluid--an enzymatic test for tuberculous pleural effusion.

Teo SK, Chio LF.

Singapore Med J. 1987 Jun;28(3):220-4. No abstract available.

PMID:
3659974
26.

Serum immunoglobulin E levels in normal children.

Quak SH, Chio LF, Teo J, Wong HB.

J Singapore Paediatr Soc. 1987;29(1):68-71. No abstract available.

PMID:
3501038
27.

How useful is skin test in predicting the presence of serum allergen specific IgE.

Quak SH, Teo J, Chio LF, Wong HB.

J Singapore Paediatr Soc. 1987;29(3-4):150-3. No abstract available.

PMID:
3450969
28.

Congenital enzymopenic methaemoglobinaemia.

Kueh YK, Chio LF, Guan R.

Ann Acad Med Singapore. 1986 Apr;15(2):250-4.

PMID:
3752898
29.

Lactate production in type B hyperlactataemia due to infective encephalopathy.

Aiyathurai JE, Wong HB, Quak SH, Low PS, Sothy SP, Sivanandasingham P, Jacob E, Chio LF.

Ann Acad Med Singapore. 1986 Jan;15(1):32-9.

PMID:
3707032
30.

Simple febrile convulsions--a transient viral encephalopathy.

Aiyathurai JE, Yip WC, Wong HB, Sothy SP, Jacob E, Chio LF.

J Singapore Paediatr Soc. 1985;27(3-4):194-9. No abstract available.

PMID:
3831603
31.

Reference values for 24 biochemical constituents of children in Singapore.

Chio LF, Vellayappan K, Tan IK, Chua KS, Wong HB.

Ann Acad Med Singapore. 1984 Jan;13(1):85-90.

PMID:
6517511
32.

Repeated transfusions and serological markers of hepatitis A and hepatitis B.

Quak SH, Ooi BC, Tan KP, Chio LF, Aw SE.

J Singapore Paediatr Soc. 1984;26(1-2):94-7. No abstract available.

PMID:
6503237
33.

Role of glucose homeostatic mechanisms in viral infections.

Aiyathurai JE, Wong HB, Quak SH, Sothy SP, Chio LF, Jacob E, Doraisingham S.

Ann Clin Biochem. 1983 May;20(Pt 3):142-8.

PMID:
6881897
34.

The significance of type B hyperlactataemia in infective encephalopathy.

Aiyathurai JE, Wong HB, Quak SH, Jacob E, Chio LF, Sothy SP.

Ann Acad Med Singapore. 1983 Jan;12(1):115-25.

PMID:
6859794
35.

Study on workers exposed to cadmium in alkaline storage battery manufacturing and PVC compounding.

Chan OY, Tan KT, Kwok SF, Chio LF.

Ann Acad Med Singapore. 1982 Jan;11(1):122-9.

PMID:
7073222
36.

Metabolic changes in simple febrile convulsions.

Yip WC, Aiyathurai JE, Chio LF, Jacob E, Wong HB.

J Singapore Paediatr Soc. 1981;23(1-2):25-9. No abstract available.

PMID:
7343777
37.

Primary hepatocellular carcinoma developing in a female patient on long term oral contraceptives--a case report.

Oon CJ, Chan SH, Chiang SC, Chio LF, Chua KL, Yo SL.

Ann Acad Med Singapore. 1980 Jul;9(3):402-4.

PMID:
6260007
38.
39.

The evaluation of tumour marker proteins in the diagnosis of primary hepatocellular carcinoma.

Oon CJ, Yo SL, Chio LF, Chua D, Tan YO.

Ann Acad Med Singapore. 1980 Apr;9(2):228-33.

PMID:
6158907
40.

Hepatitis B virus and alphafetoprotein in liver diseases in Singapore.

Chan SH, Chen F, Chio LF, Ho KT, Law CH, Leong SF, Mathew T, Ng PL, Oon CJ, Seah CS, Simons MJ, Tan A, Tan IK.

Singapore Med J. 1980 Apr;21(2):506-8. No abstract available.

PMID:
6156492
41.

Physical-chemical and biological degradation studies on DDT analogues with altered aliphatic moieties.

Coats JR, Metcalf RL, Kapoor IP, Chio LC, Boyle PA.

J Agric Food Chem. 1979 Sep-Oct;27(5):1016-22. No abstract available.

PMID:
546944
42.

Reference values for serum immunoglobulins and complement C3 and C4 of Singapore children.

Chio LF, Vellayappan K, Tan IK, Wong HB.

J Singapore Paediatr Soc. 1979 Sep-Dec;21(3-4):210-7. No abstract available.

PMID:
262489
44.

Familial primary hepatocellular carcinoma.

Oon CJ, Yo SL, Chua D, Chio LF, Tan L, Chang CH, Chan SH.

Singapore Med J. 1978 Dec;19(4):218-9. No abstract available.

PMID:
220734
45.

Tubular functions in lupus nephropathy Singapore glomerulonephritis study group.

Feng PH, Chan HC, Jacob E, Chio LF, Oon CJ, Sinniah R.

J Med Assoc Thai. 1978 Jan;61 Suppl 1:170-6. No abstract available.

PMID:
627789
46.

Serum ionized calcium in nephrotic syndrome.

Lim P, Jacob E, Chio LF, Pwee HS.

Q J Med. 1976 Jul;45(179):421-6.

PMID:
948544
47.

An abnormal requirement for iron in dystrophic chickens.

Chio LF, Bunden K, Vohra P, Kratzer FH.

Poult Sci. 1976 Mar;55(2):808-13.

PMID:
819915
48.

Lipid composition and synthesis in the muscles of normal and dystrophic chickens.

Chio LF, Peterson DW, Kratzer FH.

Can J Biochem. 1972 Dec;50(12):1267-72. No abstract available.

PMID:
4345912
49.

Heat stability of human serum alkaline phosphatase in bone and liver diseases.

Tan IK, Chio LF, Teow-Suah L.

Clin Chim Acta. 1972 Oct;41:329-34. No abstract available.

PMID:
4645241

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