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Items: 25

1.

TAF1-gene editing alters the morphology and function of the cerebellum and cerebral cortex.

Janakiraman U, Yu J, Moutal A, Chinnasamy D, Boinon L, Batchelor SN, Anandhan A, Khanna R, Nelson MA.

Neurobiol Dis. 2019 Dec;132:104539. doi: 10.1016/j.nbd.2019.104539. Epub 2019 Jul 22.

2.

Timing and intensity of exposure to interferon-γ critically determines the function of monocyte-derived dendritic cells.

Kerkar SP, Chinnasamy D, Hadi N, Melenhorst J, Muranski P, Spyridonidis A, Ito S, Weber G, Yin F, Hensel N, Wang E, Marincola FM, Barrett AJ.

Immunology. 2014 Sep;143(1):96-108. doi: 10.1111/imm.12292.

3.

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia.

Tran E, Chinnasamy D, Yu Z, Morgan RA, Lee CC, Restifo NP, Rosenberg SA.

J Exp Med. 2013 Jun 3;210(6):1125-35. doi: 10.1084/jem.20130110. Epub 2013 May 27.

4.

Simultaneous targeting of tumor antigens and the tumor vasculature using T lymphocyte transfer synergize to induce regression of established tumors in mice.

Chinnasamy D, Tran E, Yu Z, Morgan RA, Restifo NP, Rosenberg SA.

Cancer Res. 2013 Jun 1;73(11):3371-80. doi: 10.1158/0008-5472.CAN-12-3913. Epub 2013 Apr 30.

5.

Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice.

Chinnasamy D, Yu Z, Kerkar SP, Zhang L, Morgan RA, Restifo NP, Rosenberg SA.

Clin Cancer Res. 2012 Mar 15;18(6):1672-83. doi: 10.1158/1078-0432.CCR-11-3050. Epub 2012 Jan 30.

6.

SPLAT-OrB reveals competitive attraction as a mechanism of mating disruption in oriental beetle (Coleoptera: Scarabaeidae).

Rodriguez-Saona C, Polk D, Holdcraft R, Chinnasamy D, Mafra-Neto A.

Environ Entomol. 2010 Dec;39(6):1980-9. doi: 10.1603/EN10062.

PMID:
22182565
7.

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

Kerkar SP, Goldszmid RS, Muranski P, Chinnasamy D, Yu Z, Reger RN, Leonardi AJ, Morgan RA, Wang E, Marincola FM, Trinchieri G, Rosenberg SA, Restifo NP.

J Clin Invest. 2011 Dec;121(12):4746-57. doi: 10.1172/JCI58814. Epub 2011 Nov 7.

8.

Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies.

Kerkar SP, Sanchez-Perez L, Yang S, Borman ZA, Muranski P, Ji Y, Chinnasamy D, Kaiser AD, Hinrichs CS, Klebanoff CA, Scott CD, Gattinoni L, Morgan RA, Rosenberg SA, Restifo NP.

J Immunother. 2011 May;34(4):343-52. doi: 10.1097/CJI.0b013e3182187600.

9.

Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice.

Chinnasamy D, Yu Z, Theoret MR, Zhao Y, Shrimali RK, Morgan RA, Feldman SA, Restifo NP, Rosenberg SA.

J Clin Invest. 2010 Nov;120(11):3953-68. doi: 10.1172/JCI43490. Epub 2010 Oct 11.

10.
11.

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer.

Shrimali RK, Yu Z, Theoret MR, Chinnasamy D, Restifo NP, Rosenberg SA.

Cancer Res. 2010 Aug 1;70(15):6171-80. doi: 10.1158/0008-5472.CAN-10-0153. Epub 2010 Jul 14.

12.

Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA.

J Immunol. 2010 Jun 1;184(11):5988-98. doi: 10.4049/jimmunol.1000189. Epub 2010 Apr 28.

13.

Production of multicistronic HIV-1 based lentiviral vectors.

Chinnasamy N, Shaffer J, Chinnasamy D.

Methods Mol Biol. 2009;515:137-50. doi: 10.1007/978-1-59745-559-6_9.

PMID:
19378113
14.

Plasmid DNA vaccine encoding prostatic acid phosphatase is effective in eliciting autologous antigen-specific CD8+ T cells.

Johnson LE, Frye TP, Chinnasamy N, Chinnasamy D, McNeel DG.

Cancer Immunol Immunother. 2007 Jun;56(6):885-95. Epub 2006 Nov 11.

PMID:
17102977
15.

A case of schizophrenia with complete agenesis of the corpus callosum.

Chinnasamy D, Rudd R, Velakoulis D.

Australas Psychiatry. 2006 Sep;14(3):327-30.

PMID:
16923049
16.

A mechanistic study of immune system activation by fusion of antigens with the ligand-binding domain of CTLA4.

Chinnasamy D, Tector M, Chinnasamy N, Dennert K, Kozinski KM, Oaks MK.

Cancer Immunol Immunother. 2006 Dec;55(12):1504-14. Epub 2006 Apr 13.

PMID:
16612600
17.

Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI.

Chinnasamy D, Milsom MD, Shaffer J, Neuenfeldt J, Shaaban AF, Margison GP, Fairbairn LJ, Chinnasamy N.

Virol J. 2006 Mar 15;3:14.

18.

Ex vivo generation of genetically modified dendritic cells for immunotherapy: implications of lymphocyte contamination.

Chinnasamy N, Treisman JS, Oaks MK, Hanson JP, Chinnasamy D.

Gene Ther. 2005 Feb;12(3):259-71.

PMID:
15668698
19.

Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.

Chinnasamy D, Fairbairn LJ, Neuenfeldt J, Treisman JS, Hanson JP Jr, Margison GP, Chinnasamy N.

Hum Gene Ther. 2004 Aug;15(8):758-69.

PMID:
15319033
20.

Lymphocytes.

Chinnasamy D, Candotti F.

Methods Mol Biol. 2003;229:97-105. No abstract available.

PMID:
12824624
21.

Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors.

Chinnasamy N, Chinnasamy D, Toso JF, Lapointe R, Candotti F, Morgan RA, Hwu P.

Hum Gene Ther. 2000 Sep 1;11(13):1901-9.

PMID:
10986562
22.

Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins.

Chinnasamy D, Chinnasamy N, Enriquez MJ, Otsu M, Morgan RA, Candotti F.

Blood. 2000 Aug 15;96(4):1309-16.

PMID:
10942372
23.

Enhancing hemopoietic drug resistance: a rationale for reconsidering the clinical use of mitozolomide.

Fairbairn LJ, Chinnasamy N, Lashford LS, Chinnasamy D, Rafferty JA.

Cancer Gene Ther. 2000 Feb;7(2):233-9.

24.
25.

A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents.

Jelinek J, Rafferty JA, Cmejla R, Hildinger M, Chinnasamy D, Lashford LS, Ostertag W, Margison GP, Dexter TM, Fairbairn LJ, Baum C.

Gene Ther. 1999 Aug;6(8):1489-93.

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