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Items: 46

1.

Automated Bone Age Analysis with Lossy Image Files.

Pinsker JE, Ching MSL, Chiles DP, Lustik M, Mahnke CB, Rooks VJ.

Mil Med. 2017 Sep;182(9):e1769-e1772. doi: 10.7205/MILMED-D-17-00011.

PMID:
28885935
2.

Visual Diagnosis: 9-month-old Boy with Coarse Facial Features and Hepatosplenomegaly.

Myaeng J, Ching MS, Rooks VJ.

Pediatr Rev. 2017 Apr;38(4):e13-e16. doi: 10.1542/pir.2015-0137. Review. No abstract available.

PMID:
28364056
3.

A review of factors affecting vaccine preventable disease in Japan.

Kuwabara N, Ching MS.

Hawaii J Med Public Health. 2014 Dec;73(12):376-81. Review.

4.

Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders.

Ching MS, Shen Y, Tan WH, Jeste SS, Morrow EM, Chen X, Mukaddes NM, Yoo SY, Hanson E, Hundley R, Austin C, Becker RE, Berry GT, Driscoll K, Engle EC, Friedman S, Gusella JF, Hisama FM, Irons MB, Lafiosca T, LeClair E, Miller DT, Neessen M, Picker JD, Rappaport L, Rooney CM, Sarco DP, Stoler JM, Walsh CA, Wolff RR, Zhang T, Nasir RH, Wu BL; Children's Hospital Boston Genotype Phenotype Study Group.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):937-47. doi: 10.1002/ajmg.b.31063.

5.

A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using [15O]O2.

Froomes PR, Sachinidis J, Ghabrial H, Tochon-Danguy H, Scott A, Ching MS, Morgan DJ, Angus PW.

Nucl Med Biol. 2003 Feb;30(2):93-100.

PMID:
12623107
6.

Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine.

Ching MS, Blake CL, Malek NA, Angus PW, Ghabrial H.

Xenobiotica. 2001 Nov;31(11):757-67.

PMID:
11765139
7.

Neonatal hepatic drug elimination.

Gow PJ, Ghabrial H, Smallwood RA, Morgan DJ, Ching MS.

Pharmacol Toxicol. 2001 Jan;88(1):3-15. Review.

PMID:
11169155
8.

Right heart failure impairs hepatic elimination of p-nitrophenol without inducing changes in content or latency of hepatic UDP-glucuronosyltransferases.

Ng CY, Ghabrial H, Morgan DJ, Ching MS, Smallwood RA, Angus PW.

J Pharmacol Exp Ther. 2000 Nov;295(2):830-5.

9.

Role of cytochrome P450 2D6 (CYP2D6) in the stereospecific metabolism of E- and Z-doxepin.

Haritos VS, Ghabrial H, Ahokas JT, Ching MS.

Pharmacogenetics. 2000 Oct;10(7):591-603.

PMID:
11037801
10.

Impaired elimination of propranolol due to right heart failure: drug clearance in the isolated liver and its relationship to intrinsic metabolic capacity.

Ng CY, Ghabrial H, Morgan DJ, Ching MS, Smallwood RA, Angus PW.

Drug Metab Dispos. 2000 Oct;28(10):1217-21.

11.

Neonatal hepatic propranolol elimination: studies in the isolated perfused neonatal sheep liver.

Gow PJ, Treepongkaruna S, Ghabrial H, Shulkes A, Smallwood RA, Morgan DJ, Ching MS.

J Pharm Sci. 2000 May;89(5):586-93.

PMID:
10756324
12.

Stereoselective measurement of E- and Z-doxepin and its N-desmethyl and hydroxylated metabolites by gas chromatography-mass spectrometry.

Haritos VS, Ghabrial H, Ahokas JT, Ching MS.

J Chromatogr B Biomed Sci Appl. 1999 Dec 24;736(1-2):201-8.

PMID:
10677000
13.

Fetal hepatic drug elimination.

Ring JA, Ghabrial H, Ching MS, Smallwood RA, Morgan DJ.

Pharmacol Ther. 1999 Dec;84(3):429-45. Review.

PMID:
10665839
14.

Conjugation of para-nitrophenol by the isolated perfused neonatal sheep liver.

Gow PJ, Ghabrial H, Treepongkaruna S, Shulkes A, Smallwood RA, Morgan DJ, Ching MS.

J Pharm Sci. 2000 Jan;89(1):36-44.

PMID:
10664536
15.

Uptake and excretion of sodium taurocholate by the isolated perfused neonatal sheep liver.

Gow PJ, Treepongkaruna S, Ching MS, Ghabrial H, Shulkes A, Smallwood RA, Jin CJ, Morgan DJ.

J Pharm Sci. 1999 Apr;88(4):445-9.

PMID:
10187755
16.

Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2.

Haritos VS, Ching MS, Ghabrial H, Gross AS, Taavitsainen P, Pelkonen O, Battaglia SE, Smallwood RA, Ahokas JT.

Pharmacogenetics. 1998 Oct;8(5):423-32.

PMID:
9825834
17.

Propranolol elimination by right and left fetal liver: studies in the intact isolated perfused fetal sheep liver.

Ring JA, Ghabrial H, Ching MS, Shulkes A, Smallwood RA, Morgan DJ.

J Pharmacol Exp Ther. 1998 Feb;284(2):535-41.

18.

Measurement of dexfenfluramine metabolism in rat liver microsomes by gas chromatography-mass spectrometry.

Haritos VS, Ching MS, Ghabrial H, Ahokas JT.

J Chromatogr B Biomed Sci Appl. 1997 Jun 6;693(2):327-36.

PMID:
9210436
19.

Conjugation of para-nitrophenol by isolated perfused fetal sheep liver.

Ring JA, Ghabrial H, Ching MS, Shulkes A, Smallwood RA, Morgan DJ.

Drug Metab Dispos. 1996 Dec;24(12):1378-84.

PMID:
8971145
20.

Propranolol 4- and 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2.

Ching MS, Bichara N, Blake CL, Ghabrial H, Tukey RH, Smallwood RA.

Drug Metab Dispos. 1996 Jun;24(6):692-4. No abstract available.

PMID:
8781788
21.
22.

Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine, and its metabolites.

Ching MS, Blake CL, Ghabrial H, Ellis SW, Lennard MS, Tucker GT, Smallwood RA.

Biochem Pharmacol. 1995 Sep 7;50(6):833-7.

PMID:
7575645
23.

Fetal hepatic propranolol metabolism. Studies in the isolated perfused fetal sheep liver.

Ring JA, Ghabrial H, Ching MS, Shulkes A, Smallwood RA, Morgan DJ.

Drug Metab Dispos. 1995 Feb;23(2):190-6.

PMID:
7736910
24.

Hepatic uptake and excretion of [14C]sodium taurocholate by the isolated perfused fetal sheep liver.

Ring JA, Ghabrial H, Ching MS, Potocnik S, Shulkes A, Smallwood RA, Morgan DJ.

Biochem Pharmacol. 1994 Aug 17;48(4):667-74.

PMID:
8080439
25.

Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast.

Ellis SW, Ching MS, Watson PF, Henderson CJ, Simula AP, Lennard MS, Tucker GT, Woods HF.

Biochem Pharmacol. 1992 Aug 18;44(4):617-20.

PMID:
1510710
26.

Quinidine single dose pharmacokinetics and pharmacodynamics are unaltered by omeprazole.

Ching MS, Elliott SL, Stead CK, Murdoch RT, Devenish-Meares S, Morgan DJ, Smallwood RA.

Aliment Pharmacol Ther. 1991 Oct;5(5):523-31.

PMID:
1793783
27.

The expression of human cytochrome P450IA1 in the yeast Saccharomyces cerevisiae.

Ching MS, Lennard MS, Tucker GT, Woods HF, Kelly DE, Kelly SL.

Biochem Pharmacol. 1991 Jul 25;42(4):753-8.

PMID:
1867632
28.

Disposition of the diastereoisomers quinine and quinidine in the ovine fetus.

Czuba MA, Morgan DJ, Ching MS, Mihaly GW, Ghabrial H, Hardy KJ, Smallwood RA.

J Pharm Sci. 1991 May;80(5):445-8.

PMID:
1880724
29.

Oral bioavailability of omeprazole before and after chronic therapy in patients with duodenal ulcer.

Ching MS, Mihaly GW, Angus PW, Morgan DJ, Devenish-Meares S, Yeomans ND, Smallwood RA.

Br J Clin Pharmacol. 1991 Feb;31(2):166-70.

30.

Ontogeny of fetal renal organic cation excretion: a study with cimetidine and ranitidine during the latter half of gestation in the pregnant ewe.

Czuba MA, Morgan DJ, Ching MS, Mihaly GW, Hardy KJ, Smallwood RA.

J Pharmacol Exp Ther. 1990 Dec;255(3):1177-82.

PMID:
2262900
31.

Measurement of underivatised metoprolol enantiomers in human plasma by high-performance liquid chromatography with a chiral stationary phase.

Ching MS, Lennard MS, Gregory A, Tucker GT.

J Chromatogr. 1989 Dec 29;497:313-8. No abstract available.

PMID:
2625469
33.

Influence of maternal plasma protein binding on fetal unbound plasma concentration of propranolol in the pregnant ewe.

Morgan DJ, Mihaly GW, Czuba MA, Ching MS, Hardy KJ, Smallwood RA.

J Pharm Sci. 1988 Oct;77(10):835-7.

PMID:
3236224
34.

Effects of gestational age on the disposition of propranolol in pregnant sheep.

Czuba MA, Mihaly GW, Ching MS, Morgan DJ, Hardy KJ, Smallwood RA.

J Pharmacol Exp Ther. 1988 Oct;247(1):279-82.

PMID:
3171976
35.

Mechanism of triamterene transfer across the human placenta.

Ching MS, Czuba MA, Mihaly GW, Morgan DJ, Hyman KM, Paull JD, Smallwood RA.

J Pharmacol Exp Ther. 1988 Sep;246(3):1093-7.

PMID:
3418511
36.

Differences in the binding of quinine and quinidine to plasma proteins.

Mihaly GW, Ching MS, Klejn MB, Paull J, Smallwood RA.

Br J Clin Pharmacol. 1987 Dec;24(6):769-74.

37.

Low clearance of cimetidine across the human placenta.

Ching MS, Mihaly GW, Morgan DJ, Date NM, Hardy KJ, Smallwood RA.

J Pharmacol Exp Ther. 1987 Jun;241(3):1006-9.

PMID:
3598898
38.

High-performance liquid chromatographic analysis of harmol and its conjugated metabolites after enzyme hydrolysis in biological fluids.

Ching MS, Mihaly GW, Angus PW, Anderson JD, Smallwood RA.

J Chromatogr. 1986 Jul 11;380(1):190-5. No abstract available.

PMID:
3745384
39.

Placental transfer of omeprazole in maternal and fetal sheep.

Ching MS, Morgan DJ, Mihaly GW, Hardy KJ, Smallwood RA.

Dev Pharmacol Ther. 1986;9(5):323-31.

PMID:
3780367
40.

Fetal exposure to cimetidine following chronic administration to pregnant sheep.

Ching MS, Jones DB, Morgan DJ, Mihaly GW, Hardy KJ, Smallwood RA.

Res Commun Chem Pathol Pharmacol. 1985 Oct;50(1):139-42.

PMID:
4081307
42.

The inhibitory effects of ranitidine and cimetidine on propranolol elimination by the rat isolated perfused liver.

Jones DB, Ching MS, Morgan DJ, Anderson JD, Smallwood RA.

J Pharm Pharmacol. 1985 Mar;37(3):196-8.

PMID:
2858568
43.

Liquid chromatographic analysis of cimetidine with procainamide as internal standard.

Ching MS, Mihaly GW, Jones DB, Smallwood RA.

J Pharm Sci. 1984 Jul;73(7):1015. No abstract available.

PMID:
6470945
44.

Placental transfer and renal elimination of cimetidine in maternal and fetal sheep.

Mihaly GW, Jones DB, Morgan DJ, Ching MS, Webster LK, Smallwood RA, Hardy KJ.

J Pharmacol Exp Ther. 1983 Nov;227(2):441-5.

PMID:
6631723
45.

Elimination of amphotericin B in impaired renal function.

Morgan DJ, Ching MS, Raymond K, Bury RW, Mashford ML, Kong B, Sabto J, Gurr FW, Somogyi AA.

Clin Pharmacol Ther. 1983 Aug;34(2):248-53.

PMID:
6872420
46.

Absorption of orally administered amphotericin B lozenges.

Ching MS, Raymond K, Bury RW, Mashford ML, Morgan DJ.

Br J Clin Pharmacol. 1983 Jul;16(1):106-8.

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