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Items: 10


Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Berney M, Boinett C, González-Candelas F, Young DB, Gagneux S, Jacobs WR Jr, Parkhill J, Cortes T, Comas I.

Nat Commun. 2019 Sep 5;10(1):3994. doi: 10.1038/s41467-019-11948-6.


Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Sánchez-Busó L, Corander J, Gagneux S, Harris SR, Young D, González-Candelas F, Comas I.

Sci Adv. 2019 Jun 12;5(6):eaaw3307. doi: 10.1126/sciadv.aaw3307. eCollection 2019 Jun.


Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis.

Cancino-Muñoz I, Moreno-Molina M, Furió V, Goig GA, Torres-Puente M, Chiner-Oms Á, Villamayor LM, Sanz F, Guna-Serrano MR, Comas I.

J Infect Dis. 2019 Jun 19;220(2):316-320. doi: 10.1093/infdis/jiz104.


Large genomics datasets shed light on the evolution of the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Comas I.

Infect Genet Evol. 2019 Aug;72:10-15. doi: 10.1016/j.meegid.2019.02.028. Epub 2019 Feb 26.


Simplified Model to Survey Tuberculosis Transmission in Countries Without Systematic Molecular Epidemiology Programs.

Domínguez J, Acosta F, Pérez-Lago L, Sambrano D, Batista V, De La Guardia C, Abascal E, Chiner-Oms Á, Comas I, González P, Bravo J, Del Cid P, Rosas S, Muñoz P, Goodridge A, García de Viedma D.

Emerg Infect Dis. 2019 Mar;25(3):507-514. doi: 10.3201/eid2503.181593.


Whole genome sequencing-based analysis of tuberculosis (TB) in migrants: rapid tools for cross-border surveillance and to distinguish between recent transmission in the host country and new importations.

Abascal E, Pérez-Lago L, Martínez-Lirola M, Chiner-Oms Á, Herranz M, Chaoui I, Comas I, El Messaoudi MD, Cárdenas JAG, Santantón S, Bouza E, García-de-Viedma D.

Euro Surveill. 2019 Jan;24(4). doi: 10.2807/1560-7917.ES.2019.24.4.1800005.


Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks AM, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren RM, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell TC, Posey J.

Sci Rep. 2018 Oct 18;8(1):15382. doi: 10.1038/s41598-018-33731-1.


Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity.

Chiner-Oms Á, González-Candelas F, Comas I.

Sci Rep. 2018 Feb 28;8(1):3813. doi: 10.1038/s41598-018-22237-5.


Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts.

Herranz M, Pole I, Ozere I, Chiner-Oms Á, Martínez-Lirola M, Pérez-García F, Gijón P, Serrano MJR, Romero LC, Cuevas O, Comas I, Bouza E, Pérez-Lago L, García-de-Viedma D.

Front Microbiol. 2018 Jan 19;8:2661. doi: 10.3389/fmicb.2017.02661. eCollection 2017.


EvalMSA: A Program to Evaluate Multiple Sequence Alignments and Detect Outliers.

Chiner-Oms A, González-Candelas F.

Evol Bioinform Online. 2016 Nov 28;12:277-284. eCollection 2016.

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