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Items: 1 to 50 of 66

1.

Direct utilization of purple sweet potato by sake yeasts to produce an anthocyanin-rich alcoholic beverage.

Lee JY, Im YK, Ko HM, Chin JE, Kim IC, Lee HB, Bai S.

Biotechnol Lett. 2015 Jul;37(7):1439-45. doi: 10.1007/s10529-015-1811-7. Epub 2015 Mar 17.

PMID:
25778801
2.

Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.

Boehm M, Hepworth D, Loria PM, Norquay LD, Filipski KJ, Chin JE, Cameron KO, Brenner M, Bonnette P, Cabral S, Conn E, Ebner DC, Gautreau D, Hadcock J, Lee EC, Mathiowetz AM, Morin M, Rogers L, Smith A, VanVolkenburg M, Carpino PA.

ACS Med Chem Lett. 2013 Sep 16;4(11):1079-84. doi: 10.1021/ml400275z. eCollection 2013 Nov 14.

3.

Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Gorla SK, Kavitha M, Zhang M, Chin JE, Liu X, Striepen B, Makowska-Grzyska M, Kim Y, Joachimiak A, Hedstrom L, Cuny GD.

J Med Chem. 2013 May 23;56(10):4028-43. doi: 10.1021/jm400241j. Epub 2013 May 13.

4.

Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries.

Londregan AT, Piotrowski DW, Futatsugi K, Warmus JS, Boehm M, Carpino PA, Chin JE, Janssen AM, Roush NS, Buxton J, Hinchey T.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1407-11. doi: 10.1016/j.bmcl.2012.12.076. Epub 2013 Jan 5.

PMID:
23337601
5.

Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists.

Piotrowski DW, Futatsugi K, Warmus JS, Orr ST, Freeman-Cook KD, Londregan AT, Wei L, Jennings SM, Herr M, Coffey SB, Jiao W, Storer G, Hepworth D, Wang J, Lavergne SY, Chin JE, Hadcock JR, Brenner MB, Wolford AC, Janssen AM, Roush NS, Buxton J, Hinchey T, Kalgutkar AS, Sharma R, Flynn DA.

ACS Med Chem Lett. 2012 Nov 9;4(1):63-8. doi: 10.1021/ml300277t. eCollection 2013 Jan 10.

6.

Raw starch fermentation to ethanol by an industrial distiller's yeast strain of Saccharomyces cerevisiae expressing glucoamylase and α-amylase genes.

Kim HR, Im YK, Ko HM, Chin JE, Kim IC, Lee HB, Bai S.

Biotechnol Lett. 2011 Aug;33(8):1643-8. doi: 10.1007/s10529-011-0613-9. Epub 2011 Apr 9.

PMID:
21479627
7.

Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selective CCK1 receptor agonist for the potential treatment of obesity.

Elliott RL, Cameron KO, Chin JE, Bartlett JA, Beretta EE, Chen Y, Jardine Pda S, Dubins JS, Gillaspy ML, Hargrove DM, Kalgutkar AS, LaFlamme JA, Lame ME, Martin KA, Maurer TS, Nardone NA, Oliver RM, Scott DO, Sun D, Swick AG, Trebino CE, Zhang Y.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6797-801. doi: 10.1016/j.bmcl.2010.08.115. Epub 2010 Sep 28.

PMID:
20851601
8.

A selective cannabinoid-1 receptor antagonist, PF-95453, reduces body weight and body fat to a greater extent than pair-fed controls in obese monkeys.

Wagner JD, Zhang L, Kavanagh K, Ward GM, Chin JE, Hadcock JR, Auerbach BJ, Harwood HJ Jr.

J Pharmacol Exp Ther. 2010 Oct;335(1):103-13. doi: 10.1124/jpet.110.168187. Epub 2010 Jul 6.

PMID:
20605903
9.

Construction of a direct starch-fermenting industrial strain of Saccharomyces cerevisiae producing glucoamylase, alpha-amylase and debranching enzyme.

Kim JH, Kim HR, Lim MH, Ko HM, Chin JE, Lee HB, Kim IC, Bai S.

Biotechnol Lett. 2010 May;32(5):713-9. doi: 10.1007/s10529-010-0212-1. Epub 2010 Feb 4.

PMID:
20131079
10.

Simultaneous degradation of phytic acid and starch by an industrial strain of Saccharomyces cerevisiae producing phytase and alpha-amylase.

Lim MH, Lee OH, Chin JE, Ko HM, Kim IC, Lee HB, Im SY, Bai S.

Biotechnol Lett. 2008 Dec;30(12):2125-30. doi: 10.1007/s10529-008-9799-x. Epub 2008 Jul 16.

PMID:
18629438
11.

Galanin function in the central nervous system.

Walton KM, Chin JE, Duplantier AJ, Mather RJ.

Curr Opin Drug Discov Devel. 2006 Sep;9(5):560-70. Review.

PMID:
17002216
12.

Construction of an amylolytic industrial strain of Saccharomyces cerevisiae containing the Schwanniomyces occidentalis alpha-amylase gene.

Kang NY, Park JN, Chin JE, Lee HB, Im SY, Bai S.

Biotechnol Lett. 2003 Nov;25(21):1847-51.

PMID:
14677710
13.

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease.

Sly LM, Krzesicki RF, Brashler JR, Buhl AE, McKinley DD, Carter DB, Chin JE.

Brain Res Bull. 2001 Dec;56(6):581-8.

PMID:
11786245
14.

Immunogenicity, safety and lot consistency in adults of a chromatographically purified Vero-cell rabies vaccine: a randomized, double-blind trial with human diploid cell rabies vaccine.

Jones RL, Froeschle JE, Atmar RL, Matthews JS, Sanders R, Pardalos J, Moeller L, Chin JE, Famula M, Briggs DJ, Lang J.

Vaccine. 2001 Sep 14;19(32):4635-43.

PMID:
11535311
15.

Pattern of cytokine and adhesion molecule mRNA in hapten-induced relapsing colon inflammation in the rat.

Sun FF, Lai PS, Yue G, Yin K, Nagele RG, Tong DM, Krzesicki RF, Chin JE, Wong PY.

Inflammation. 2001 Feb;25(1):33-45.

PMID:
11293664
17.

Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes.

Parker JC, McPherson RK, Andrews KM, Levy CB, Dubins JS, Chin JE, Perry PV, Hulin B, Perry DA, Inagaki T, Dekker KA, Tachikawa K, Sugie Y, Treadway JL.

Diabetes. 2000 Dec;49(12):2079-86.

PMID:
11118010
18.
19.

Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma.

Chin JE, Hatfield CA, Winterrowd GE, Krzesicki RF, Shull KL, Fidler SF, Kolbasa KP, Brashler JR, Griffin RL, Fleming WE, Justen JM, Banitt LS, Bundy GL, Richards IM.

J Pharmacol Exp Ther. 1999 Jul;290(1):188-95.

PMID:
10381775
20.

Involvement of intercellular adhesion molecule-1 in the antigen-induced infiltration of eosinophils and lymphocytes into the airways in a murine model of pulmonary inflammation.

Chin JE, Winterrowd GE, Hatfield CA, Brashler JR, Griffin RL, Vonderfecht SL, Kolbasa KP, Fidler SF, Shull KL, Krzesicki RF, Ready KA, Dunn CJ, Sly LM, Staite ND, Richards IM.

Am J Respir Cell Mol Biol. 1998 Feb;18(2):158-67.

PMID:
9476902
21.

Roles of adhesion molecules ICAM-1 and alpha4 integrin in antigen-induced changes in microvascular permeability associated with lung inflammation in sensitized brown Norway rats.

Taylor BM, Kolbasa KP, Chin JE, Richards IM, Fleming WE, Griffin RL, Fidler SF, Sun FF.

Am J Respir Cell Mol Biol. 1997 Dec;17(6):757-66.

PMID:
9409563
22.

Intercellular adhesion molecule-1-deficient mice have antibody responses but impaired leukocyte recruitment.

Hatfield CA, Brashler JR, Winterrowd GE, Bell FP, Griffin RL, Fidler SF, Kolbasa KP, Mobley JL, Shull KL, Richards IM, Chin JE.

Am J Physiol. 1997 Sep;273(3 Pt 1):L513-23.

PMID:
9316484
23.

Identification of cytokine and adhesion molecule mRNA in murine lung tissue and isolated T cells and eosinophils by semi-quantitative reverse transcriptase-polymerase chain reaction.

Krzesicki RF, Winterrowd GE, Brashler JR, Hatfield CA, Griffin RL, Fidler SF, Kolbasa KP, Shull KL, Richards IM, Chin JE.

Am J Respir Cell Mol Biol. 1997 Jun;16(6):693-701.

PMID:
9191471
24.

Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1.

Chin JE, Hatfield CA, Winterrowd GE, Brashler JR, Vonderfecht SL, Fidler SF, Griffin RL, Kolbasa KP, Krzesicki RF, Sly LM, Staite ND, Richards IM.

Am J Physiol. 1997 Feb;272(2 Pt 1):L219-29.

PMID:
9124372
25.

Cytokine networks in allergic lung inflammation: an opportunity for drug intervention.

Mobley JL, Chin JE, Richards IM.

Expert Opin Investig Drugs. 1997 Jan;6(1):1-6.

PMID:
15989556
26.

Pulmonary ferritin: differential effects of hyperoxic lung injury on subunit mRNA levels.

Ryan TP, Krzesicki RF, Blakeman DP, Chin JE, Griffin RL, Richards IM, Aust SD, Petry TW.

Free Radic Biol Med. 1997;22(5):901-8.

PMID:
9119260
27.

Safety and immunogenicity of Lyssavac Berna human diploid cell rabies vaccine in healthy adults.

Briggs DJ, Dreesen DW, Morgan P, Chin JE, Seedle CD, Cryz L, Glück R, Cryz SJ.

Vaccine. 1996 Oct;14(14):1361-5.

PMID:
9004446
28.

Role of intercellular adhesion molecule-1 in antigen-induced lung inflammation in brown Norway rats.

Richards IM, Kolbasa KP, Winterrowd GE, Hatfield CA, Vonderfecht SL, Fidler SF, Griffin RL, Brashler JR, Krzesicki RF, Lane CL, Anderson DC, Sly LM, Staite ND, Chin JE.

Am J Physiol. 1996 Aug;271(2 Pt 1):L267-76.

PMID:
8770066
29.

Role of very late activation antigen-4 in the antigen-induced accumulation of eosinophils and lymphocytes in the lungs and airway lumen of sensitized brown Norway rats.

Richards IM, Kolbasa KP, Hatfield CA, Winterrowd GE, Vonderfecht SL, Fidler SF, Griffin RL, Brashler JR, Krzesicki RF, Sly LM, Ready KA, Staite ND, Chin JE.

Am J Respir Cell Mol Biol. 1996 Aug;15(2):172-83.

PMID:
8703473
30.

Phenotypic analysis of airway eosinophils and lymphocytes in a Th-2-driven murine model of pulmonary inflammation.

Watkins AD, Hatfield CA, Fidler SF, Winterrowd GE, Brashler JR, Sun FF, Taylor BM, Vonderfecht SL, Conder GA, Holgate ST, Chin JE, Richards IM.

Am J Respir Cell Mol Biol. 1996 Jul;15(1):20-34.

PMID:
8679219
31.

Synthesis of novel 2,4-diaminopyrrolo-[2,3-d]pyrimidines with antioxidant, neuroprotective, and antiasthma activity.

Bundy GL, Ayer DE, Banitt LS, Belonga KL, Mizsak SA, Palmer JR, Tustin JM, Chin JE, Hall ED, Linseman KL, et al.

J Med Chem. 1995 Oct 13;38(21):4161-3. No abstract available.

PMID:
7473542
32.

Phenotypic characterization of T lymphocytes emigrating into lung tissue and the airway lumen after antigen inhalation in sensitized mice.

Kennedy JD, Hatfield CA, Fidler SF, Winterrowd GE, Haas JV, Chin JE, Richards IM.

Am J Respir Cell Mol Biol. 1995 Jun;12(6):613-23.

PMID:
7766426
33.

Attenuation of oxidant-induced lung injury by 21-aminosteroids (lazaroids): correlation with the mRNA expression for E-selectin, P-selectin, ICAM-1, and VCAM-1.

Griffin RL, Krzesicki RF, Fidler SF, Rosenbloom CL, Auchampach JA, Manning AM, Haas JV, Cammarata SK, Chin JE, Richards IM.

Environ Health Perspect. 1994 Dec;102 Suppl 10:193-200.

34.

A comparison of the monocyte monolayer assay with 51chromium red cell recovery for determining the clinical significance of red cell alloantibodies.

Davey RJ, Esty SS, Chin JE, Mallory D.

Immunohematology. 1994;10(3):90-4. No abstract available.

PMID:
15945802
35.

Biochemical mechanisms of insulin resistance.

Roth RA, Liu F, Chin JE.

Horm Res. 1994;41 Suppl 2:51-5. Review.

PMID:
8088704
36.
38.
39.

Substrates and signalling complexes: the tortured path to insulin action.

Roth RA, Zhang B, Chin JE, Kovacina K.

J Cell Biochem. 1992 Jan;48(1):12-8. Review.

PMID:
1316356
40.

T lymphocyte adhesion to human synovial fibroblasts. Role of cytokines and the interaction between intercellular adhesion molecule 1 and CD11a/CD18.

Krzesicki RF, Fleming WE, Winterrowd GE, Hatfield CA, Sanders ME, Chin JE.

Arthritis Rheum. 1991 Oct;34(10):1245-53.

PMID:
1681812
41.

Evidence for hybrid rodent and human insulin receptors in transfected cells.

Chin JE, Tavaré JM, Ellis L, Roth RA.

J Biol Chem. 1991 Aug 25;266(24):15587-90.

42.

Platelet-derived growth factor potentiates cellular responses of articular chondrocytes to interleukin-1.

Smith RJ, Justen JM, Sam LM, Rohloff NA, Ruppel PL, Brunden MN, Chin JE.

Arthritis Rheum. 1991 Jun;34(6):697-706.

PMID:
2053915
43.
44.
46.

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

Noonan KE, Beck C, Holzmayer TA, Chin JE, Wunder JS, Andrulis IL, Gazdar AF, Willman CL, Griffith B, Von Hoff DD, Roninson IB.

Proc Natl Acad Sci U S A. 1990 Sep;87(18):7160-4.

48.

Substrates of the insulin receptor kinase.

Yonezawa K, Endemann G, Kovacina KS, Chin JE, Stover C, Roth RA.

Adv Second Messenger Phosphoprotein Res. 1990;24:266-72. No abstract available.

PMID:
2169807
49.

Structure and expression of the human MDR (P-glycoprotein) gene family.

Chin JE, Soffir R, Noonan KE, Choi K, Roninson IB.

Mol Cell Biol. 1989 Sep;9(9):3808-20.

50.

Phospholipase A2 (PLA2) activity in rabbit chondrocytes.

Stevens TM, Chin JE, McGowan M, Giannaras J, Kerr JS.

Agents Actions. 1989 Jun;27(3-4):385-7.

PMID:
2801329

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