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Items: 35


Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.

Chin HG, Ponnaluri VK, Zhang G, Estève PO, Schaus SE, Hansen U, Pradhan S.

Oncotarget. 2016 Dec 13;7(50):83627-83640. doi: 10.18632/oncotarget.13271.


Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression.

Estève PO, Zhang G, Ponnaluri VK, Deepti K, Chin HG, Dai N, Sagum C, Black K, Corrêa IR Jr, Bedford MT, Cheng X, Pradhan S.

Nucleic Acids Res. 2016 Feb 29;44(4):1642-56. doi: 10.1093/nar/gkv1162. Epub 2015 Nov 8.


Management of Second Trimester Fetal Demise in a Noncommunicating Uterine Horn.

Hillman RT, Chin HG, Mody SK.

Case Rep Obstet Gynecol. 2015;2015:927037. doi: 10.1155/2015/927037. Epub 2015 Jun 3.


Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation.

Zhang G, Estève PO, Chin HG, Terragni J, Dai N, Corrêa IR Jr, Pradhan S.

Nucleic Acids Res. 2015 Jul 13;43(12):6112-24. doi: 10.1093/nar/gkv518. Epub 2015 May 18.


Physical activity in women: current guidelines and strategies for promoting compliance.

Chin HG.

Clin Obstet Gynecol. 2014 Sep;57(3):456-64. doi: 10.1097/GRF.0000000000000045. Review.


Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.

Estève PO, Terragni J, Deepti K, Chin HG, Dai N, Espejo A, Corrêa IR Jr, Bedford MT, Pradhan S.

J Biol Chem. 2014 Mar 21;289(12):8277-87. doi: 10.1074/jbc.M113.525279. Epub 2014 Feb 3.


MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.

Laget S, Miotto B, Chin HG, Estève PO, Roberts RJ, Pradhan S, Defossez PA.

Epigenetics. 2014 Apr;9(4):546-56. doi: 10.4161/epi.27695. Epub 2014 Jan 16.


Evaluation of UDP-GlcN derivatives for selective labeling of 5-(hydroxymethyl)cytosine.

Dai N, Bitinaite J, Chin HG, Pradhan S, Corrêa IR Jr.

Chembiochem. 2013 Nov 4;14(16):2144-52. doi: 10.1002/cbic.201300294. Epub 2013 Sep 17.


Identification of DNMT1 selective antagonists using a novel scintillation proximity assay.

Kilgore JA, Du X, Melito L, Wei S, Wang C, Chin HG, Posner B, Pradhan S, Ready JM, Williams NS.

J Biol Chem. 2013 Jul 5;288(27):19673-84. doi: 10.1074/jbc.M112.443895. Epub 2013 May 13.


Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants.

Du J, Zhong X, Bernatavichute YV, Stroud H, Feng S, Caro E, Vashisht AA, Terragni J, Chin HG, Tu A, Hetzel J, Wohlschlegel JA, Pradhan S, Patel DJ, Jacobsen SE.

Cell. 2012 Sep 28;151(1):167-80. doi: 10.1016/j.cell.2012.07.034.


Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.

Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, Andrews WH, Sarkar D, Schaus SE, Hansen U.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4503-8. doi: 10.1073/pnas.1121601109. Epub 2012 Mar 6.


Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes.

Kinney SM, Chin HG, Vaisvila R, Bitinaite J, Zheng Y, Estève PO, Feng S, Stroud H, Jacobsen SE, Pradhan S.

J Biol Chem. 2011 Jul 15;286(28):24685-93. doi: 10.1074/jbc.M110.217083. Epub 2011 May 24.


The de novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA-directed DNA methylation in Arabidopsis thaliana.

Henderson IR, Deleris A, Wong W, Zhong X, Chin HG, Horwitz GA, Kelly KA, Pradhan S, Jacobsen SE.

PLoS Genet. 2010 Oct 28;6(10):e1001182. doi: 10.1371/journal.pgen.1001182.


A unique family of Mrr-like modification-dependent restriction endonucleases.

Zheng Y, Cohen-Karni D, Xu D, Chin HG, Wilson G, Pradhan S, Roberts RJ.

Nucleic Acids Res. 2010 Sep;38(16):5527-34. doi: 10.1093/nar/gkq327. Epub 2010 May 5.


SET7/9 mediated methylation of non-histone proteins in mammalian cells.

Pradhan S, Chin HG, Estève PO, Jacobsen SE.

Epigenetics. 2009 Aug 16;4(6):383-7. Epub 2009 Aug 6. Review.


Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells.

Estève PO, Chin HG, Benner J, Feehery GR, Samaranayake M, Horwitz GA, Jacobsen SE, Pradhan S.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5076-81. doi: 10.1073/pnas.0810362106. Epub 2009 Mar 12.


CXXC domain of human DNMT1 is essential for enzymatic activity.

Pradhan M, Estève PO, Chin HG, Samaranayke M, Kim GD, Pradhan S.

Biochemistry. 2008 Sep 23;47(38):10000-9. doi: 10.1021/bi8011725. Epub 2008 Aug 29.


Leptin-regulated gene expression in MCF-7 breast cancer cells: mechanistic insights into leptin-regulated mammary tumor growth and progression.

Perera CN, Chin HG, Duru N, Camarillo IG.

J Endocrinol. 2008 Nov;199(2):221-33. doi: 10.1677/JOE-08-0215. Epub 2008 Aug 20. Erratum in: J Endocrinol. 2008 Dec;199(3):499.


Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation.

Ding N, Zhou H, Esteve PO, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, Boyer TG.

Mol Cell. 2008 Aug 8;31(3):347-59. doi: 10.1016/j.molcel.2008.05.023.


Automethylation of G9a and its implication in wider substrate specificity and HP1 binding.

Chin HG, Estève PO, Pradhan M, Benner J, Patnaik D, Carey MF, Pradhan S.

Nucleic Acids Res. 2007;35(21):7313-23. Epub 2007 Oct 25.


Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells.

Estève PO, Chin HG, Pradhan S.

J Biol Chem. 2007 Jan 26;282(4):2615-25. Epub 2006 Nov 22.


Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication.

Estève PO, Chin HG, Smallwood A, Feehery GR, Gangisetty O, Karpf AR, Carey MF, Pradhan S.

Genes Dev. 2006 Nov 15;20(22):3089-103. Epub 2006 Nov 3.


Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.

Chin HG, Pradhan M, Estève PO, Patnaik D, Evans TC Jr, Pradhan S.

Biochemistry. 2005 Oct 4;44(39):12998-3006.


Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase.

Estève PO, Patnaik D, Chin HG, Benner J, Teitell MA, Pradhan S.

Nucleic Acids Res. 2005 Jun 6;33(10):3211-23. Print 2005.


Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters.

Estève PO, Chin HG, Pradhan S.

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1000-5. Epub 2005 Jan 18.


Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.

Patnaik D, Chin HG, Estève PO, Benner J, Jacobsen SE, Pradhan S.

J Biol Chem. 2004 Dec 17;279(51):53248-58. Epub 2004 Oct 14.


Protein trans-splicing in transgenic plant chloroplast: reconstruction of herbicide resistance from split genes.

Chin HG, Kim GD, Marin I, Mersha F, Evans TC Jr, Chen L, Xu MQ, Pradhan S.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4510-5. Epub 2003 Apr 1.


Inhibitor of striate conditionally suppresses cell proliferation in variegated maize.

Park SH, Chin HG, Cho MJ, Martienssen RA, Han Cd.

Genes Dev. 2000 Apr 15;14(8):1005-16.


Molecular analysis of rice plants harboring an Ac/Ds transposable element-mediated gene trapping system.

Chin HG, Choe MS, Lee SH, Park SH, Koo JC, Kim NY, Lee JJ, Oh BG, Yi GH, Kim SC, Choi HC, Cho MJ, Han CD.

Plant J. 1999 Sep;19(5):615-23.


Androgen replacement in postmenopausal women.

Chin HG.

West J Med. 1996 Dec;165(6):373-4. No abstract available.


Operative laparoscopy versus laparotomy for the management of ectopic pregnancy: a prospective trial.

Murphy AA, Nager CW, Wujek JJ, Kettel LM, Torp VA, Chin HG.

Fertil Steril. 1992 Jun;57(6):1180-5.


The efficacy of biobehavioral and compliance interventions in the adjunctive treatment of mild pregnancy-induced hypertension.

Somers PJ, Gevirtz RN, Jasin SE, Chin HG.

Biofeedback Self Regul. 1989 Dec;14(4):309-18.


Energetics of swimming in fishes using different methods of locomotion: I. Labriform swimmers.

Gordon MS, Chin HG, Vojkovich M.

Fish Physiol Biochem. 1989 Nov;6(6):341-52. doi: 10.1007/BF01875604.


Angiographic embolization of intractable puerperal hematomas.

Chin HG, Scott DR, Resnik R, Davis GB, Lurie AL.

Am J Obstet Gynecol. 1989 Feb;160(2):434-8.


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