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Items: 18


TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates.

Singh RK, Haka AS, Asmal A, Barbosa-Lorenzi VC, Grosheva I, Chin HF, Xiong Y, Hla T, Maxfield FR.

Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):86-102. doi: 10.1161/ATVBAHA.119.313200. Epub 2019 Oct 10.


Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism.

Singh RK, Haka AS, Brumfield A, Grosheva I, Bhardwaj P, Chin HF, Xiong Y, Hla T, Maxfield FR.

J Lipid Res. 2017 Oct;58(10):1977-1987. doi: 10.1194/jlr.M076398. Epub 2017 Aug 16.


Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation.

Haka AS, Singh RK, Grosheva I, Hoffner H, Capetillo-Zarate E, Chin HF, Anandasabapathy N, Maxfield FR.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2092-103. doi: 10.1161/ATVBAHA.115.305843. Epub 2015 Aug 20.


Modulation of lipid metabolism in glycyrrhizic acid-treated rats fed on a high-calorie diet and exposed to short or long-term stress.

Yaw HP, Ton SH, Chin HF, Karim MK, Fernando HA, Kadir KA.

Int J Physiol Pathophysiol Pharmacol. 2015 Mar 20;7(1):61-75. eCollection 2015.


Mechanism of cytokinetic contractile ring constriction in fission yeast.

Stachowiak MR, Laplante C, Chin HF, Guirao B, Karatekin E, Pollard TD, O'Shaughnessy B.

Dev Cell. 2014 Jun 9;29(5):547-561. doi: 10.1016/j.devcel.2014.04.021.


Irregularities in glucose metabolism induced by stress and high-calorie diet can be attenuated by glycyrrhizic acid.

Yaw HP, Ton SH, Amanda S, Kong IG, Cheng HS, Fernando HA, Chin HF, Kadir KA.

Int J Physiol Pathophysiol Pharmacol. 2014 Dec 15;6(4):172-84. eCollection 2014.


Stress and Its Effects on Glucose Metabolism and 11β-HSD Activities in Rats Fed on a Combination of High-Fat and High-Sucrose Diet with Glycyrrhizic Acid.

Fernando HA, Chin HF, Ton SH, Abdul Kadir K.

J Diabetes Res. 2013;2013:190395. doi: 10.1155/2013/190395. Epub 2013 Mar 18.


STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC.

Garbarino J, Pan M, Chin HF, Lund FW, Maxfield FR, Breslow JL.

J Lipid Res. 2012 Dec;53(12):2716-25. doi: 10.1194/jlr.M032227. Epub 2012 Oct 2.


Actin network architecture can determine myosin motor activity.

Reymann AC, Boujemaa-Paterski R, Martiel JL, Guérin C, Cao W, Chin HF, De La Cruz EM, Théry M, Blanchoin L.

Science. 2012 Jun 8;336(6086):1310-4. doi: 10.1126/science.1221708.


Angiopoietin-like 4: a decade of research.

Zhu P, Goh YY, Chin HF, Kersten S, Tan NS.

Biosci Rep. 2012 Jun;32(3):211-9. doi: 10.1042/BSR20110102. Review.


Actin filament dynamics in the actomyosin VI complex is regulated allosterically by calcium-calmodulin light chain.

Prochniewicz E, Pierre A, McCullough BR, Chin HF, Cao W, Saunders LP, Thomas DD, De La Cruz EM.

J Mol Biol. 2011 Oct 28;413(3):584-92. doi: 10.1016/j.jmb.2011.08.058. Epub 2011 Sep 6.


Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin.

Shiroguchi K, Chin HF, Hannemann DE, Muneyuki E, De La Cruz EM, Kinosita K Jr.

PLoS Biol. 2011 Apr;9(4):e1001031. doi: 10.1371/journal.pbio.1001031. Epub 2011 Apr 12.


A myosin V inhibitor based on privileged chemical scaffolds.

Islam K, Chin HF, Olivares AO, Saunders LP, De La Cruz EM, Kapoor TM.

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8484-8. doi: 10.1002/anie.201004026. No abstract available.


Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex.

Prochniewicz E, Chin HF, Henn A, Hannemann DE, Olivares AO, Thomas DD, De La Cruz EM.

J Mol Biol. 2010 Feb 26;396(3):501-9. doi: 10.1016/j.jmb.2009.11.063. Epub 2009 Dec 4.


Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor.

Chin HF, Cai Y, Menon S, Ferro-Novick S, Reinisch KM, De La Cruz EM.

J Mol Biol. 2009 Jun 5;389(2):275-88. doi: 10.1016/j.jmb.2009.03.068. Epub 2009 Apr 8.


Emergency department thoracotomy for pericardiac tamponade.

Lau CK, Chin HF, Ong FH, Eng KH.

Singapore Med J. 2008 Dec;49(12):e382-4.


The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes.

Cai Y, Chin HF, Lazarova D, Menon S, Fu C, Cai H, Sclafani A, Rodgers DW, De La Cruz EM, Ferro-Novick S, Reinisch KM.

Cell. 2008 Jun 27;133(7):1202-13. doi: 10.1016/j.cell.2008.04.049.

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