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Items: 35

1.

A broad survey of DNA sequence data simulation tools.

Alosaimi S, Bandiang A, van Biljon N, Awany D, Thami PK, Tchamga MSS, Kiran A, Messaoud O, Hassan RIM, Mugo J, Ahmed A, Bope CD, Allali I, Mazandu GK, Mulder NJ, Chimusa ER.

Brief Funct Genomics. 2019 Dec 23. pii: elz033. doi: 10.1093/bfgp/elz033. [Epub ahead of print]

PMID:
31867604
2.

Computational/in silico methods in drug target and lead prediction.

Agamah FE, Mazandu GK, Hassan R, Bope CD, Thomford NE, Ghansah A, Chimusa ER.

Brief Bioinform. 2019 Nov 10. pii: bbz103. doi: 10.1093/bib/bbz103. [Epub ahead of print]

PMID:
31711157
3.

Genome-wide heritability analysis of severe malaria resistance reveals evidence of polygenic inheritance.

Damena D, Chimusa ER.

Hum Mol Genet. 2019 Nov 6. pii: ddz258. doi: 10.1093/hmg/ddz258. [Epub ahead of print]

PMID:
31691794
4.

Population Structure and Implications on the Genetic Architecture of HIV-1 Phenotypes Within Southern Africa.

Thami PK, Chimusa ER.

Front Genet. 2019 Sep 27;10:905. doi: 10.3389/fgene.2019.00905. eCollection 2019. Review.

5.

Multi-stage Association Analysis of Glioblastoma Gene Expressions with Texture and Spatial Patterns.

Elsheikh SSM, Bakas S, Mulder NJ, Chimusa ER, Davatzikos C, Crimi A.

Brainlesion. 2019;11383:239-250. doi: 10.1007/978-3-030-11723-8_24. Epub 2019 Jan 26.

6.

Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects.

Damena D, Denis A, Golassa L, Chimusa ER.

BMC Med Genomics. 2019 Aug 14;12(1):120. doi: 10.1186/s12920-019-0564-x. Review.

7.

Dissecting in silico Mutation Prediction of Variants in African Genomes: Challenges and Perspectives.

Bope CD, Chimusa ER, Nembaware V, Mazandu GK, de Vries J, Wonkam A.

Front Genet. 2019 Jun 25;10:601. doi: 10.3389/fgene.2019.00601. eCollection 2019.

8.

Genetic diversity and drug susceptibility profiles of Mycobacterium tuberculosis obtained from Saint Peter's TB specialized Hospital, Ethiopia.

Damena D, Tolosa S, Hailemariam M, Zewude A, Worku A, Mekonnen B, Mohammed T, Admasu A, Chimusa ER, Mihret A, Abebe T, Ameni G.

PLoS One. 2019 Jun 24;14(6):e0218545. doi: 10.1371/journal.pone.0218545. eCollection 2019.

9.

Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa.

Mnika K, Mazandu GK, Jonas M, Pule GD, Chimusa ER, Hanchard NA, Wonkam A.

Front Genet. 2019 May 28;10:509. doi: 10.3389/fgene.2019.00509. eCollection 2019.

10.

Concordance of genetic variation that increases risk for tourette syndrome and that influences its underlying neurocircuitry.

Mufford M, Cheung J, Jahanshad N, van der Merwe C, Ding L, Groenewold N, Koen N, Chimusa ER, Dalvie S, Ramesar R, Knowles JA, Lochner C, Hibar DP, Paschou P, van den Heuvel OA, Medland SE, Scharf JM, Mathews CA, Thompson PM, Stein DJ; Psychiatric Genomics Consortium - Tourette Syndrome working group.

Transl Psychiatry. 2019 Mar 22;9(1):120. doi: 10.1038/s41398-019-0452-3.

11.

Host and Microbiome Genome-Wide Association Studies: Current State and Challenges.

Awany D, Allali I, Dalvie S, Hemmings S, Mwaikono KS, Thomford NE, Gomez A, Mulder N, Chimusa ER.

Front Genet. 2019 Jan 22;9:637. doi: 10.3389/fgene.2018.00637. eCollection 2018. Review.

12.

Tantalizing dilemma in risk prediction from disease scoring statistics.

Awany D, Allali I, Chimusa ER.

Brief Funct Genomics. 2018 Jul 22;18(4):211-219. doi: 10.1093/bfgp/ely040. Review.

13.

Dating admixture events is unsolved problem in multi-way admixed populations.

Chimusa ER, Defo J, Thami PK, Awany D, Mulisa DD, Allali I, Ghaza H, Moussa A, Mazandu GK.

Brief Bioinform. 2018 Nov 19. doi: 10.1093/bib/bby112. [Epub ahead of print]

PMID:
30462157
14.

Detecting genetic modifiers of spondyloepimetaphyseal dysplasia with joint laxity in the Caucasian Afrikaner community.

Chimusa ER, Beighton P, Kumuthini J, Ramesar RS.

Hum Mol Genet. 2019 Apr 1;28(7):1053-1063. doi: 10.1093/hmg/ddy373.

PMID:
30358852
15.

A comprehensive survey of models for dissecting local ancestry deconvolution in human genome.

Geza E, Mugo J, Mulder NJ, Wonkam A, Chimusa ER, Mazandu GK.

Brief Bioinform. 2019 Sep 27;20(5):1709-1724. doi: 10.1093/bib/bby044.

PMID:
30010715
16.

Beta-globin gene haplotypes and selected Malaria-associated variants among black Southern African populations.

Pule GD, Chimusa ER, Mnika K, Mhandire K, Kampira E, Dandara C, Wonkam A.

Glob Health Epidemiol Genom. 2017 Nov 27;2:e17. doi: 10.1017/gheg.2017.14. eCollection 2017.

17.

Post genome-wide association analysis: dissecting computational pathway/network-based approaches.

Chimusa ER, Dalvie S, Dandara C, Wonkam A, Mazandu GK.

Brief Bioinform. 2019 Mar 25;20(2):690-700. doi: 10.1093/bib/bby035.

18.

Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.

Choudhury A, Ramsay M, Hazelhurst S, Aron S, Bardien S, Botha G, Chimusa ER, Christoffels A, Gamieldien J, Sefid-Dashti MJ, Joubert F, Meintjes A, Mulder N, Ramesar R, Rees J, Scholtz K, Sengupta D, Soodyall H, Venter P, Warnich L, Pepper MS.

Nat Commun. 2017 Dec 12;8(1):2062. doi: 10.1038/s41467-017-00663-9.

19.

Clinical and genetic factors are associated with pain and hospitalisation rates in sickle cell anaemia in Cameroon.

Wonkam A, Mnika K, Ngo Bitoungui VJ, Chetcha Chemegni B, Chimusa ER, Dandara C, Kengne AP.

Br J Haematol. 2018 Jan;180(1):134-146. doi: 10.1111/bjh.15011. Epub 2017 Dec 3.

20.
21.

A multi-scenario genome-wide medical population genetics simulation framework.

Mugo JW, Geza E, Defo J, Elsheikh SSM, Mazandu GK, Mulder NJ, Chimusa ER.

Bioinformatics. 2017 Oct 1;33(19):2995-3002. doi: 10.1093/bioinformatics/btx369.

22.

South African student protests, 2015 - 2016: The aftermath viewed through Medical Science Honours students at the University of Cape Town.

Dandara C, Chimusa ER, Wonkam A.

S Afr Med J. 2017 Aug 25;107(9):12062. doi: 10.7196/SAMJ.2017.v107i9.12714. No abstract available.

PMID:
28875873
23.

Large-scale data-driven integrative framework for extracting essential targets and processes from disease-associated gene data sets.

Mazandu GK, Chimusa ER, Rutherford K, Zekeng EG, Gebremariam ZZ, Onifade MY, Mulder NJ.

Brief Bioinform. 2018 Nov 27;19(6):1141-1152. doi: 10.1093/bib/bbx052.

PMID:
28520909
24.

Clinical and genetic predictors of renal dysfunctions in sickle cell anaemia in Cameroon.

Geard A, Pule GD, Chetcha Chemegni B, Ngo Bitoungui VJ, Kengne AP, Chimusa ER, Wonkam A.

Br J Haematol. 2017 Aug;178(4):629-639. doi: 10.1111/bjh.14724. Epub 2017 May 3.

25.

Development of Bioinformatics Infrastructure for Genomics Research.

Mulder NJ, Adebiyi E, Adebiyi M, Adeyemi S, Ahmed A, Ahmed R, Akanle B, Alibi M, Armstrong DL, Aron S, Ashano E, Baichoo S, Benkahla A, Brown DK, Chimusa ER, Fadlelmola FM, Falola D, Fatumo S, Ghedira K, Ghouila A, Hazelhurst S, Isewon I, Jung S, Kassim SK, Kayondo JK, Mbiyavanga M, Meintjes A, Mohammed S, Mosaku A, Moussa A, Muhammd M, Mungloo-Dilmohamud Z, Nashiru O, Odia T, Okafor A, Oladipo O, Osamor V, Oyelade J, Sadki K, Salifu SP, Soyemi J, Panji S, Radouani F, Souiai O, Tastan Bishop Ö; H3ABioNet Consortium, as members of the H3Africa Consortium.

Glob Heart. 2017 Jun;12(2):91-98. doi: 10.1016/j.gheart.2017.01.005. Epub 2017 Mar 13. Review.

26.

A Genomic and Protein-Protein Interaction Analyses of Nonsyndromic Hearing Impairment in Cameroon Using Targeted Genomic Enrichment and Massively Parallel Sequencing.

Lebeko K, Manyisa N, Chimusa ER, Mulder N, Dandara C, Wonkam A.

OMICS. 2017 Feb;21(2):90-99. doi: 10.1089/omi.2016.0171. Epub 2017 Jan 11.

27.

Minimum information required for a DMET experiment reporting.

Kumuthini J, Mbiyavanga M, Chimusa ER, Pathak J, Somervuo P, Van Schaik RH, Dolzan V, Mizzi C, Kalideen K, Ramesar RS, Macek M, Patrinos GP, Squassina A.

Pharmacogenomics. 2016 Sep;17(14):1533-45. doi: 10.2217/pgs-2016-0015. Epub 2016 Aug 22.

28.

Gene Ontology semantic similarity tools: survey on features and challenges for biological knowledge discovery.

Mazandu GK, Chimusa ER, Mulder NJ.

Brief Bioinform. 2017 Sep 1;18(5):886-901. doi: 10.1093/bib/bbw067.

PMID:
27473066
29.

"Broadband" Bioinformatics Skills Transfer with the Knowledge Transfer Programme (KTP): Educational Model for Upliftment and Sustainable Development.

Chimusa ER, Mbiyavanga M, Masilela V, Kumuthini J.

PLoS Comput Biol. 2015 Nov 19;11(11):e1004512. doi: 10.1371/journal.pcbi.1004512. eCollection 2015 Nov.

30.

ancGWAS: a post genome-wide association study method for interaction, pathway and ancestry analysis in homogeneous and admixed populations.

Chimusa ER, Mbiyavanga M, Mazandu GK, Mulder NJ.

Bioinformatics. 2016 Feb 15;32(4):549-56. doi: 10.1093/bioinformatics/btv619. Epub 2015 Oct 27.

31.

A-DaGO-Fun: an adaptable Gene Ontology semantic similarity-based functional analysis tool.

Mazandu GK, Chimusa ER, Mbiyavanga M, Mulder NJ.

Bioinformatics. 2016 Feb 1;32(3):477-9. doi: 10.1093/bioinformatics/btv590. Epub 2015 Oct 17.

32.

A genomic portrait of haplotype diversity and signatures of selection in indigenous southern African populations.

Chimusa ER, Meintjies A, Tchanga M, Mulder N, Seoighe C, Soodyall H, Ramesar R.

PLoS Genet. 2015 Mar 26;11(3):e1005052. doi: 10.1371/journal.pgen.1005052. eCollection 2015 Mar. Erratum in: PLoS Genet. 2015 Jul;11(7):e1005363. Seioghe, Cathal [corrected to Seoighe, Cathal].

33.

A panel of ancestry informative markers for the complex five-way admixed South African coloured population.

Daya M, van der Merwe L, Galal U, Möller M, Salie M, Chimusa ER, Galanter JM, van Helden PD, Henn BM, Gignoux CR, Hoal E.

PLoS One. 2013 Dec 20;8(12):e82224. doi: 10.1371/journal.pone.0082224. eCollection 2013.

34.

Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method.

Chimusa ER, Daya M, Möller M, Ramesar R, Henn BM, van Helden PD, Mulder NJ, Hoal EG.

PLoS One. 2013 Sep 16;8(9):e73971. doi: 10.1371/journal.pone.0073971. eCollection 2013.

35.

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

Chimusa ER, Zaitlen N, Daya M, Möller M, van Helden PD, Mulder NJ, Price AL, Hoal EG.

Hum Mol Genet. 2014 Feb 1;23(3):796-809. doi: 10.1093/hmg/ddt462. Epub 2013 Sep 20.

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