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Items: 15


Appropriation of GPIb╬▒ from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.

Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH, Kuravi SJ, Payne H, Price JMJ, Kavanagh D, Iqbal AJ, Lax S, Kalia N, Brill A, Thomas SG, Belli A, Crombie N, Adams RA, Evans SA, Deckmyn H, Lord JM, Harrison P, Watson SP, Nash GB, Rainger GE.

Haematologica. 2019 Aug 29. pii: haematol.2018.215145. doi: 10.3324/haematol.2018.215145. [Epub ahead of print]


Triggering the Resolution of Immune Mediated Inflammatory Diseases: Can Targeting Leukocyte Migration Be the Answer?

Hopkin SJ, Lewis JW, Krautter F, Chimen M, McGettrick HM.

Front Pharmacol. 2019 Mar 1;10:184. doi: 10.3389/fphar.2019.00184. eCollection 2019.


Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease.

Harrison MJ, Chimen M, Hussain M, Iqbal AJ, Senis YA, Nash GB, Watson SP, Rainger GE.

J Cell Mol Med. 2018 Sep;22(9):4317-4327. doi: 10.1111/jcmm.13721. Epub 2018 Jul 4.


Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation.

Borgognone A, Shantsila E, Worrall SM, Prompunt E, Loka T, Loudon BL, Chimen M, Ed Rainger G, Lord JM, Turner A, Nightingale P, Feelisch M, Kirchhof P, Lip GYH, Watson SP, Frenneaux MP, Madhani M.

Cardiovasc Res. 2018 Aug 1;114(10):1313-1323. doi: 10.1093/cvr/cvy087.


ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration.

Reyat JS, Chimen M, Noy PJ, Szyroka J, Rainger GE, Tomlinson MG.

J Immunol. 2017 Jul 15;199(2):666-676. doi: 10.4049/jimmunol.1600713. Epub 2017 Jun 9.


Endocrine Regulation of Lymphocyte Trafficking In Vitro.

Apta BH, Chimen M, Mcgettrick HM.

Methods Mol Biol. 2017;1591:101-119. doi: 10.1007/978-1-4939-6931-9_8.


Introduction: T Cell Trafficking in Inflammation and Immunity.

Chimen M, Apta BH, Mcgettrick HM.

Methods Mol Biol. 2017;1591:73-84. doi: 10.1007/978-1-4939-6931-9_6. Review.


Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface.

Chimen M, Yates CM, McGettrick HM, Ward LS, Harrison MJ, Apta B, Dib LH, Imhof BA, Harrison P, Nash GB, Rainger GE.

J Immunol. 2017 Apr 1;198(7):2834-2843. doi: 10.4049/jimmunol.1601281. Epub 2017 Feb 13.


The role of platelets in the recruitment of leukocytes during vascular disease.

Ed Rainger G, Chimen M, Harrison MJ, Yates CM, Harrison P, Watson SP, Lordkipanidz├ę M, Nash GB.

Platelets. 2015;26(6):507-20. doi: 10.3109/09537104.2015.1064881. Epub 2015 Jul 21. Review.


Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.

Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LSK, Buckley CD, Nash GB, Narendran P, Rainger GE.

Nat Med. 2015 May;21(5):467-475. doi: 10.1038/nm.3842. Epub 2015 Apr 20.


The time has come to test the beta cell preserving effects of exercise in patients with new onset type 1 diabetes.

Narendran P, Solomon TP, Kennedy A, Chimen M, Andrews RC.

Diabetologia. 2015 Jan;58(1):10-8. doi: 10.1007/s00125-014-3412-8. Epub 2014 Nov 4. Review.


A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.

Robertson AL, Holmes GR, Bojarczuk AN, Burgon J, Loynes CA, Chimen M, Sawtell AK, Hamza B, Willson J, Walmsley SR, Anderson SR, Coles MC, Farrow SN, Solari R, Jones S, Prince LR, Irimia D, Rainger GE, Kadirkamanathan V, Whyte MK, Renshaw SA.

Sci Transl Med. 2014 Feb 26;6(225):225ra29. doi: 10.1126/scitranslmed.3007672.


Does exercise improve glycaemic control in type 1 diabetes? A systematic review and meta-analysis.

Kennedy A, Nirantharakumar K, Chimen M, Pang TT, Hemming K, Andrews RC, Narendran P.

PLoS One. 2013;8(3):e58861. doi: 10.1371/journal.pone.0058861. Epub 2013 Mar 15. Review.


Inhibition of islet immunoreactivity by adiponectin is attenuated in human type 1 diabetes.

Pang TT, Chimen M, Goble E, Dixon N, Benbow A, Eldershaw SE, Thompson D, Gough SC, Narendran P.

J Clin Endocrinol Metab. 2013 Mar;98(3):E418-28. doi: 10.1210/jc.2012-3516. Epub 2013 Feb 5.


What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review.

Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P.

Diabetologia. 2012 Mar;55(3):542-51. doi: 10.1007/s00125-011-2403-2. Epub 2011 Dec 22. Review.


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