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Items: 1 to 50 of 286

1.

Two is better than one: difunctional high-affinity PSMA probes based on a [CpM(CO)3] (M = Re/99mTc) scaffold.

Frei A, Fischer E, Childs BC, Holland JP, Alberto R.

Dalton Trans. 2019 Oct 7;48(39):14600-14605. doi: 10.1039/c9dt02506e.

PMID:
31549121
2.

An Atomistic Understanding of the Unusual Thermal Behavior of the Molecular Oxide Tc2O7.

Mast DS, Lawler KV, Childs BC, Czerwinski KR, Sattelberger AP, Poineau F, Forster PM.

Inorg Chem. 2019 May 6;58(9):5468-5475. doi: 10.1021/acs.inorgchem.8b02368. Epub 2019 Apr 22.

PMID:
31007022
3.

Inhibition of 'jumping genes' promotes healthy ageing.

Childs B, van Deursen J.

Nature. 2019 Feb;566(7742):46-48. doi: 10.1038/d41586-018-07553-0. No abstract available.

PMID:
30728507
4.

Cellular Identification and Quantification of Senescence-Associated β-Galactosidase Activity In Vivo.

Childs BG, Bussian TJ, Baker DJ.

Methods Mol Biol. 2019;1896:31-38. doi: 10.1007/978-1-4939-8931-7_4.

5.

Results and Outcomes After Midshaft Clavicle Fracture: Matched Pair Analysis of Operative Versus Nonoperative Management.

Napora JK, Grimberg DC, Childs BR, Vallier HA.

Orthopedics. 2018 Sep 1;41(5):e689-e694. doi: 10.3928/01477447-20180724-04. Epub 2018 Jul 27.

PMID:
30052262
6.

Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS-Mutated Hepatocellular Carcinoma.

Lim HY, Merle P, Weiss KH, Yau T, Ross P, Mazzaferro V, Blanc JF, Ma YT, Yen CJ, Kocsis J, Choo SP, Sukeepaisarnjaroen W, Gérolami R, Dufour JF, Gane EJ, Ryoo BY, Peck-Radosavljevic M, Dao T, Yeo W, Lamlertthon W, Thongsawat S, Teufel M, Roth K, Reis D, Childs BH, Krissel H, Llovet JM.

Clin Cancer Res. 2018 Oct 1;24(19):4650-4661. doi: 10.1158/1078-0432.CCR-17-3588. Epub 2018 Jun 27.

7.

In response.

Childs BR, Vallier HA, Nash CL.

J Orthop Trauma. 2018 Jun;32(6):e244. doi: 10.1097/BOT.0000000000001165. No abstract available.

PMID:
29762434
8.

Senescent cells: a therapeutic target for cardiovascular disease.

Childs BG, Li H, van Deursen JM.

J Clin Invest. 2018 Apr 2;128(4):1217-1228. doi: 10.1172/JCI95146. Epub 2018 Apr 2. Review.

9.

Treatment of Hypovitaminosis D in an Orthopaedic Trauma Population.

Andres BA, Childs BR, Vallier HA.

J Orthop Trauma. 2018 Apr;32(4):e129-e133. doi: 10.1097/BOT.0000000000001076.

PMID:
29558375
10.

Strategies for implementing effective mealtime insulin therapy in type 2 diabetes.

Peyrot M, Bailey TS, Childs BP, Reach G.

Curr Med Res Opin. 2018 Jun;34(6):1153-1162. doi: 10.1080/03007995.2018.1440200. Epub 2018 Mar 12.

PMID:
29429377
11.

Unraveling the mystery of "tech red" - a volatile technetium oxide.

Lawler KV, Childs BC, Czerwinski KR, Sattelberger AP, Poineau F, Forster PM.

Chem Commun (Camb). 2018 Jan 31;54(10):1261-1264. doi: 10.1039/c7cc09191e.

PMID:
29340381
12.

Early Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury Appears Safe and May Improve Outcomes.

Flanagan CD, Childs BR, Moore TA, Vallier HA.

Spine (Phila Pa 1976). 2018 Aug;43(16):1110-1116. doi: 10.1097/BRS.0000000000002537.

PMID:
29283957
13.

Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma.

Dreyling M, Santoro A, Mollica L, Leppä S, Follows GA, Lenz G, Kim WS, Nagler A, Panayiotidis P, Demeter J, Özcan M, Kosinova M, Bouabdallah K, Morschhauser F, Stevens DA, Trevarthen D, Giurescu M, Cupit L, Liu L, Köchert K, Seidel H, Peña C, Yin S, Hiemeyer F, Garcia-Vargas J, Childs BH, Zinzani PL.

J Clin Oncol. 2017 Dec 10;35(35):3898-3905. doi: 10.1200/JCO.2017.75.4648. Epub 2017 Oct 4. Erratum in: J Clin Oncol. 2018 Feb 10;36(5):521.

PMID:
28976790
14.

Presentation Coagulopathy and Persistent Acidosis Predict Complications in Orthopaedic Trauma Patients.

Childs BR, Verhotz DR, Moore TA, Vallier HA.

J Orthop Trauma. 2017 Dec;31(12):617-623. doi: 10.1097/BOT.0000000000000957. Erratum in: J Orthop Trauma. 2018 Oct;32(10):e420.

PMID:
28827507
15.

Senescent cells: an emerging target for diseases of ageing.

Childs BG, Gluscevic M, Baker DJ, Laberge RM, Marquess D, Dananberg J, van Deursen JM.

Nat Rev Drug Discov. 2017 Oct;16(10):718-735. doi: 10.1038/nrd.2017.116. Epub 2017 Jul 21. Review.

16.

Phase II study of copanlisib, a PI3K inhibitor, in relapsed or refractory, indolent or aggressive lymphoma.

Dreyling M, Morschhauser F, Bouabdallah K, Bron D, Cunningham D, Assouline SE, Verhoef G, Linton K, Thieblemont C, Vitolo U, Hiemeyer F, Giurescu M, Garcia-Vargas J, Gorbatchevsky I, Liu L, Koechert K, Peña C, Neves M, Childs BH, Zinzani PL.

Ann Oncol. 2017 Sep 1;28(9):2169-2178. doi: 10.1093/annonc/mdx289.

17.

Three-dimensional kinematics of the equine metacarpophalangeal joint using x-ray reconstruction of moving morphology - a pilot study.

Childs BA, Pugliese BR, Carballo CT, Miranda DL, Brainerd EL, Kirker-Head CA.

Vet Comp Orthop Traumatol. 2017 Jul 20;30(4):248-255. doi: 10.3415/VCOT-16-06-0095. Epub 2017 May 5.

PMID:
28474730
18.

Canine histiocytic sarcoma presenting as a target lesion on brain magnetic resonance imaging and as a solitary pulmonary mass.

Hicks J, Barber R, Childs B, Kirejczyk SG, Uhl EW.

Vet Radiol Ultrasound. 2018 Nov;59(6):E66-E70. doi: 10.1111/vru.12502. Epub 2017 Apr 17.

PMID:
28419635
19.

Molecular and Electronic Structures of M2O7 (M = Mn, Tc, Re).

Lawler KV, Childs BC, Mast DS, Czerwinski KR, Sattelberger AP, Poineau F, Forster PM.

Inorg Chem. 2017 Mar 6;56(5):2448-2458. doi: 10.1021/acs.inorgchem.6b02503. Epub 2017 Feb 21.

PMID:
28221038
20.

Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer.

Van Laethem JL, Riess H, Jassem J, Haas M, Martens UM, Weekes C, Peeters M, Ross P, Bridgewater J, Melichar B, Cascinu S, Saramak P, Michl P, Van Brummelen D, Zaniboni A, Schmiegel W, Dueland S, Giurescu M, Garosi VL, Roth K, Schulz A, Seidel H, Rajagopalan P, Teufel M, Childs BH.

Target Oncol. 2017 Feb;12(1):97-109. doi: 10.1007/s11523-016-0469-y.

PMID:
27975152
21.

Senescent intimal foam cells are deleterious at all stages of atherosclerosis.

Childs BG, Baker DJ, Wijshake T, Conover CA, Campisi J, van Deursen JM.

Science. 2016 Oct 28;354(6311):472-477. Epub 2016 Oct 27.

22.

Ditechnetium Heptoxide Revisited: Solid-State, Gas-Phase, and Theoretical Studies.

Childs BC, Braband H, Lawler K, Mast DS, Bigler L, Stalder U, Forster PM, Czerwinski KR, Alberto R, Sattelberger AP, Poineau F.

Inorg Chem. 2016 Oct 17;55(20):10445-10452. doi: 10.1021/acs.inorgchem.6b01683. Epub 2016 Oct 4.

PMID:
27700061
23.

Factors Affecting Functional Outcomes After Clavicle Fracture.

Napora JK, Grimberg D, Childs BR, Vallier HA.

J Am Acad Orthop Surg. 2016 Oct;24(10):721-7. doi: 10.5435/JAAOS-D-16-00130.

PMID:
27564794
24.

Multiple Procedures in the Initial Surgical Setting: When Do the Benefits Outweigh the Risks in Patients With Multiple System Trauma?

Childs BR, Nahm NJ, Moore TA, Vallier HA.

J Orthop Trauma. 2016 Aug;30(8):420-5. doi: 10.1097/BOT.0000000000000556.

PMID:
27441760
25.

Frequency of Recidivism in Patients With Orthopedic Trauma.

Koleszar JC, Childs BR, Vallier HA.

Orthopedics. 2016 Sep 1;39(5):300-6. doi: 10.3928/01477447-20160623-05. Epub 2016 Jul 1.

PMID:
27359281
26.

Economic Benefit of Calcium and Vitamin D Supplementation: Does It Outweigh the Cost of Nonunions?

Childs BR, Andres BA, Vallier HA.

J Orthop Trauma. 2016 Aug;30(8):e285-8. doi: 10.1097/BOT.0000000000000592.

PMID:
27010185
27.

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.

Baker DJ, Childs BG, Durik M, Wijers ME, Sieben CJ, Zhong J, Saltness RA, Jeganathan KB, Verzosa GC, Pezeshki A, Khazaie K, Miller JD, van Deursen JM.

Nature. 2016 Feb 11;530(7589):184-9. doi: 10.1038/nature16932. Epub 2016 Feb 3.

28.

Cellular senescence in aging and age-related disease: from mechanisms to therapy.

Childs BG, Durik M, Baker DJ, van Deursen JM.

Nat Med. 2015 Dec;21(12):1424-35. doi: 10.1038/nm.4000. Review.

29.

Systematic Review of the Use of Phytochemicals for Management of Pain in Cancer Therapy.

Harrison AM, Heritier F, Childs BG, Bostwick JM, Dziadzko MA.

Biomed Res Int. 2015;2015:506327. doi: 10.1155/2015/506327. Epub 2015 Oct 20. Review.

30.

American Spinal Injury Association Impairment Scale Predicts the Need for Tracheostomy After Cervical Spinal Cord Injury.

Childs BR, Moore TA, Como JJ, Vallier HA.

Spine (Phila Pa 1976). 2015 Sep 15;40(18):1407-13. doi: 10.1097/BRS.0000000000001008.

PMID:
26426711
31.

Comparison of muscle BOLD responses to arterial occlusion at 3 and 7 Tesla.

Towse TF, Childs BT, Sabin SA, Bush EC, Elder CP, Damon BM.

Magn Reson Med. 2016 Mar;75(3):1333-40. doi: 10.1002/mrm.25562. Epub 2015 Apr 17.

32.

Obesity Is Associated With More Complications and Longer Hospital Stays After Orthopaedic Trauma.

Childs BR, Nahm NJ, Dolenc AJ, Vallier HA.

J Orthop Trauma. 2015 Nov;29(11):504-9. doi: 10.1097/BOT.0000000000000324.

PMID:
25756913
33.

Spartan deficiency causes genomic instability and progeroid phenotypes.

Maskey RS, Kim MS, Baker DJ, Childs B, Malureanu LA, Jeganathan KB, Machida Y, van Deursen JM, Machida YJ.

Nat Commun. 2014 Dec 11;5:5744. doi: 10.1038/ncomms6744.

34.

Impact of available nitrogen and sugar concentration in musts on alcoholic fermentation and subsequent wine spoilage by Brettanomyces bruxellensis.

Childs BC, Bohlscheid JC, Edwards CG.

Food Microbiol. 2015 Apr;46:604-609. doi: 10.1016/j.fm.2014.10.006. Epub 2014 Oct 29.

PMID:
25475334
35.

Senescence and apoptosis: dueling or complementary cell fates?

Childs BG, Baker DJ, Kirkland JL, Campisi J, van Deursen JM.

EMBO Rep. 2014 Nov;15(11):1139-53. doi: 10.15252/embr.201439245. Epub 2014 Oct 13. Review.

36.

Cost savings associated with a multidisciplinary protocol that expedites definitive fracture care.

Childs BR, Vallier HA.

Am J Orthop (Belle Mead NJ). 2014 Jul;43(7):309-15.

PMID:
25046183
37.

Cardiac safety results from a phase II, open-label, multicenter, pilot study of two docetaxel-based regimens plus bevacizumab for the adjuvant treatment of subjects with node-positive or high-risk node-negative breast cancer.

Hurvitz SA, Bosserman LD, Chan D, Hagenstad CT, Kass FC, Smith FP, Rodriguez GI, Childs BH, Slamon DJ.

Springerplus. 2014 May 12;3:244. doi: 10.1186/2193-1801-3-244. eCollection 2014.

38.

Improved time to treatment failure with an intermittent oxaliplatin strategy: results of CONcePT.

Hochster HS, Grothey A, Hart L, Rowland K, Ansari R, Alberts S, Chowhan N, Ramanathan RK, Keaton M, Hainsworth JD, Childs BH.

Ann Oncol. 2014 Jun;25(6):1172-8. doi: 10.1093/annonc/mdu107. Epub 2014 Mar 7.

39.

Phase II multicenter study of docetaxel and bevacizumab with or without trastuzumab as first-line treatment for patients with metastatic breast cancer.

Schwartzberg LS, Badarinath S, Keaton MR, Childs BH.

Clin Breast Cancer. 2014 Jun;14(3):161-8. doi: 10.1016/j.clbc.2013.12.003. Epub 2013 Dec 27.

PMID:
24566467
40.

A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube.

Herzog TJ, Monk BJ, Rose PG, Braly P, Hines JF, Bell MC, Wenham RM, Secord AA, Roman LD, Einstein MH, Drake RD, Childs BH.

Gynecol Oncol. 2014 Mar;132(3):517-25. doi: 10.1016/j.ygyno.2014.01.035. Epub 2014 Jan 27.

41.

Addition of bevacizumab to three docetaxel regimens as adjuvant therapy for early stage breast cancer.

Yardley DA, Hart L, Waterhouse D, Whorf R, Drosick DR, Murphy P, Badarinath S, Daniel BR, Childs BH, Burris H.

Breast Cancer Res Treat. 2013 Dec;142(3):655-65. doi: 10.1007/s10549-013-2764-y. Epub 2013 Nov 21.

PMID:
24253810
42.

Acrylic nail curing UV lamps: high-intensity exposure warrants further research of skin cancer risk.

Curtis J, Tanner P, Judd C, Childs B, Hull C, Leachman S.

J Am Acad Dermatol. 2013 Dec;69(6):1069-70. doi: 10.1016/j.jaad.2013.08.032. No abstract available.

PMID:
24238177
43.

A multicenter phase II study of docetaxel, oxaliplatin, and bevacizumab in first-line therapy for unresectable locally advanced or metastatic non-squamous cell histology non-small-cell lung cancer (NSCLC).

Raez LE, Santos ES, Webb RT, Wade J, Brito RA, Karr M, Kennah A, Childs BH.

Cancer Chemother Pharmacol. 2013 Nov;72(5):1103-10. doi: 10.1007/s00280-013-2301-z. Epub 2013 Sep 22.

PMID:
24057043
44.

Hypoglycemia and diabetes: a report of a workgroup of the American Diabetes Association and the Endocrine Society.

Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J, Vigersky R.

Diabetes Care. 2013 May;36(5):1384-95. doi: 10.2337/dc12-2480. Epub 2013 Apr 15.

45.

Hypoglycemia and diabetes: a report of a workgroup of the American Diabetes Association and the Endocrine Society.

Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J, Vigersky R; American Diabetes Association; Endocrine Society.

J Clin Endocrinol Metab. 2013 May;98(5):1845-59. doi: 10.1210/jc.2012-4127. Epub 2013 Apr 15.

PMID:
23589524
46.

Ensuring quality in clinical ethics consultations: perspectives of ethicists regarding process and prior training of consultants.

Silverman HJ, Bellavance E, Childs BH.

Am J Bioeth. 2013;13(2):29-31. doi: 10.1080/15265161.2012.750393. No abstract available.

PMID:
23391058
47.
48.

HCEC pearls and pitfalls: suggested do's and don't's for healthcare ethics consultants.

American Society for Bioethics and Humanities Clinical Ethics Consultation Affairs Standing Committee, Carrese JA, Antommaria AH, Berkowitz KA, Berger J, Carrese J, Childs BH, Derse AR, Gallagher C, Gallagher JA, Goodman-Crews P, Heesters A, Jurchak M, Mitchell C, Mokwyune N, Parsi K, Powell T, Powderly KE, Rosell T, Shelton W, Smith ML, Spike J, Tarzian A, Wocial L.

J Clin Ethics. 2012 Fall;23(3):234-40.

PMID:
23256404
49.

Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial.

Mackey JR, Martin M, Pienkowski T, Rolski J, Guastalla JP, Sami A, Glaspy J, Juhos E, Wardley A, Fornander T, Hainsworth J, Coleman R, Modiano MR, Vinholes J, Pinter T, Rodríguez-Lescure A, Colwell B, Whitlock P, Provencher L, Laing K, Walde D, Price C, Hugh JC, Childs BH, Bassi K, Lindsay MA, Wilson V, Rupin M, Houé V, Vogel C; TRIO/BCIRG 001 investigators.

Lancet Oncol. 2013 Jan;14(1):72-80. doi: 10.1016/S1470-2045(12)70525-9. Epub 2012 Dec 12.

PMID:
23246022
50.

Premier's Blair Childs sees healthcare payment's future. Interview by Mark Hagland.

Childs B.

Healthc Inform. 2012 Sep;29(8):22, 28. No abstract available.

PMID:
23012907

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