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Items: 19


Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.

Issitt T, Bosseboeuf E, De Winter N, Dufton N, Gestri G, Senatore V, Chikh A, Randi AM, Raimondi C.

iScience. 2019 Jan 25;11:205-223. doi: 10.1016/j.isci.2018.12.005. Epub 2018 Dec 11.


p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.

Arcidiacono P, Webb CM, Brooke MA, Zhou H, Delaney PJ, Ng KE, Blaydon DC, Tinker A, Kelsell DP, Chikh A.

Nat Commun. 2018 Mar 9;9(1):1021. doi: 10.1038/s41467-018-03470-y.


Correction: A novel regulatory mechanism links PLCγ1 to PDK1.

Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M.

J Cell Sci. 2017 Mar 1;130(5):1016. doi: 10.1242/jcs.201491. No abstract available.


Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.

Maruthappu T, Chikh A, Fell B, Delaney PJ, Brooke MA, Levet C, Moncada-Pazos A, Ishida-Yamamoto A, Blaydon D, Waseem A, Leigh IM, Freeman M, Kelsell DP.

Nat Commun. 2017 Jan 27;8:14174. doi: 10.1038/ncomms14174.


Constitutive Autophagy and Nucleophagy during Epidermal Differentiation.

Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RFL, Bergamaschi D.

J Invest Dermatol. 2016 Jul;136(7):1460-1470. doi: 10.1016/j.jid.2016.03.016. Epub 2016 Mar 25.


Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression.

Chikh A, Ferro R, Abbott JJ, Piñeiro R, Buus R, Iezzi M, Ricci F, Bergamaschi D, Ostano P, Chiorino G, Lattanzio R, Broggini M, Piantelli M, Maffucci T, Falasca M.

Oncotarget. 2016 Apr 5;7(14):18325-45. doi: 10.18632/oncotarget.7761.


Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells.

Raimondi C, Fantin A, Lampropoulou A, Denti L, Chikh A, Ruhrberg C.

J Exp Med. 2014 Jun 2;211(6):1167-83. doi: 10.1084/jem.20132330. Epub 2014 May 26.


iASPP is a novel autophagy inhibitor in keratinocytes.

Chikh A, Sanzà P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA, Bergamaschi D.

J Cell Sci. 2014 Jul 15;127(Pt 14):3079-93. doi: 10.1242/jcs.144816. Epub 2014 Apr 28.


An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models.

Gérard C, Xiao X, Filali M, Coulombe Z, Arsenault M, Couet J, Li J, Drolet MC, Chapdelaine P, Chikh A, Tremblay JP.

Mol Ther Methods Clin Dev. 2014 Oct 8;1:14044. doi: 10.1038/mtm.2014.44. eCollection 2014.


A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins.

Chapdelaine P, Coulombe Z, Chikh A, Gérard C, Tremblay JP.

Mol Ther Nucleic Acids. 2013 Sep 3;2:e119. doi: 10.1038/mtna.2013.41.


p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.

Matin RN, Chikh A, Chong SL, Mesher D, Graf M, Sanza' P, Senatore V, Scatolini M, Moretti F, Leigh IM, Proby CM, Costanzo A, Chiorino G, Cerio R, Harwood CA, Bergamaschi D.

J Exp Med. 2013 Mar 11;210(3):581-603. doi: 10.1084/jem.20121439. Epub 2013 Feb 18.


A novel regulatory mechanism links PLCγ1 to PDK1.

Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M.

J Cell Sci. 2012 Jul 1;125(Pt 13):3153-63. doi: 10.1242/jcs.100511. Epub 2012 Mar 27. Erratum in: J Cell Sci. 2017 Mar 1;130(5):1016.


iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia.

Chikh A, Matin RN, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M, Ghimenti C, Bahta A, Khalaf S, Akgül B, Braun KM, Chiorino G, Philpott MP, Harwood CA, Bergamaschi D.

EMBO J. 2011 Sep 6;30(20):4261-73. doi: 10.1038/emboj.2011.302.


Recruitment of Cdc42 through the GAP domain of RLIP participates in remodeling of the actin cytoskeleton and is involved in Xenopus gastrulation.

Boissel L, Houssin N, Chikh A, Rynditch A, Van Hove L, Moreau J.

Dev Biol. 2007 Dec 1;312(1):331-43. Epub 2007 Sep 26.


Expression of GATA-3 in epidermis and hair follicle: relationship to p63.

Chikh A, Sayan E, Thibaut S, Lena AM, DiGiorgi S, Bernard BA, Melino G, Candi E.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):1-6. Epub 2007 Jul 2.


p63 is upstream of IKK alpha in epidermal development.

Candi E, Terrinoni A, Rufini A, Chikh A, Lena AM, Suzuki Y, Sayan BS, Knight RA, Melino G.

J Cell Sci. 2006 Nov 15;119(Pt 22):4617-22.


p63 and p73, members of the p53 gene family, transactivate PKCdelta.

Ponassi R, Terrinoni A, Chikh A, Rufini A, Lena AM, Sayan BS, Melino G, Candi E.

Biochem Pharmacol. 2006 Nov 30;72(11):1417-22. Epub 2006 Sep 7.


[This death which is necessary for life].

Ameisen JC, Chikh A, Bongiorno-Borbone L, Knight RA, Melino G.

J Soc Biol. 2005;199(3):267-76. Review. French. No abstract available.


[Incidence and morbidity of osteoarticular tuberculosis in Chernigov region].

Bachinskiĭ IuS, Chikh AP.

Probl Tuberk. 1970;48(5):6-8. Russian. No abstract available.


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