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Items: 1 to 50 of 72

1.

Bioactive 2-(Methyldithio)Pyridine-3-Carbonitrile from Persian Shallot (Allium stipitatum Regel.) Exerts Broad-Spectrum Antimicrobial Activity.

Karunanidhi A, Ghaznavi-Rad E, Jeevajothi Nathan J, Joseph N, Chigurupati S, Mohd Fauzi F, Pichika MR, Hamat RA, Lung LTT, van Belkum A, Neela V.

Molecules. 2019 Mar 13;24(6). pii: E1003. doi: 10.3390/molecules24061003.

2.

2'-Aryl and 4'-arylidene substituted pyrazolones: As potential α-amylase inhibitors.

Yousuf S, Khan KM, Salar U, Chigurupati S, Muhammad MT, Wadood A, Aldubayan M, Vijayan V, Riaz M, Perveen S.

Eur J Med Chem. 2018 Nov 5;159:47-58. doi: 10.1016/j.ejmech.2018.09.052. Epub 2018 Sep 21.

PMID:
30268823
3.

New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities.

Salar U, Khan KM, Chigurupati S, Syed S, Vijayabalan S, Wadood A, Riaz M, Ghufran M, Perveen S.

Med Chem. 2019;15(1):87-101. doi: 10.2174/1573406414666180903162243.

PMID:
30179139
4.

Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro, and in silico evaluation.

Khan M, Alam A, Khan KM, Salar U, Chigurupati S, Wadood A, Ali F, Mohammad JI, Riaz M, Perveen S.

Bioorg Chem. 2018 Dec;81:157-167. doi: 10.1016/j.bioorg.2018.07.038. Epub 2018 Aug 2.

PMID:
30125730
5.

A Zombie LIF Gene in Elephants Is Upregulated by TP53 to Induce Apoptosis in Response to DNA Damage.

Vazquez JM, Sulak M, Chigurupati S, Lynch VJ.

Cell Rep. 2018 Aug 14;24(7):1765-1776. doi: 10.1016/j.celrep.2018.07.042.

6.

Antibacterial and Antibiofilm Activities of Nonpolar Extracts of Allium stipitatum Regel. against Multidrug Resistant Bacteria.

Karunanidhi A, Ghaznavi-Rad E, Hamat RA, Pichika MR, Lung LTT, Mohd Fauzi F, Chigurupati S, van Belkum A, Neela V.

Biomed Res Int. 2018 Jul 11;2018:9845075. doi: 10.1155/2018/9845075. eCollection 2018.

7.

Identification of altered microRNAs in serum of a mouse model of Parkinson's disease.

Rosas-Hernandez H, Chigurupati S, Raymick J, Robinson B, Cuevas E, Hanig J, Sarkar S.

Neurosci Lett. 2018 Nov 20;687:1-9. doi: 10.1016/j.neulet.2018.07.022. Epub 2018 Jul 17.

PMID:
30025832
8.

Vasculoprotective Effects of Pomegranate (Punica granatum L.).

Wang D, Özen C, Abu-Reidah IM, Chigurupati S, Patra JK, Horbanczuk JO, Jóźwik A, Tzvetkov NT, Uhrin P, Atanasov AG.

Front Pharmacol. 2018 May 24;9:544. doi: 10.3389/fphar.2018.00544. eCollection 2018. Review.

9.

Synthesis, α-amylase inhibitory potential and molecular docking study of indole derivatives.

Taha M, Baharudin MS, Ismail NH, Imran S, Khan MN, Rahim F, Selvaraj M, Chigurupati S, Nawaz M, Qureshi F, Vijayabalan S.

Bioorg Chem. 2018 Oct;80:36-42. doi: 10.1016/j.bioorg.2018.05.021. Epub 2018 May 22.

PMID:
29864686
10.

Chalcones and bis-chalcones: As potential α-amylase inhibitors; synthesis, in vitro screening, and molecular modelling studies.

Tajudeen Bale A, Mohammed Khan K, Salar U, Chigurupati S, Fasina T, Ali F, Kanwal, Wadood A, Taha M, Sekhar Nanda S, Ghufran M, Perveen S.

Bioorg Chem. 2018 Sep;79:179-189. doi: 10.1016/j.bioorg.2018.05.003. Epub 2018 May 7.

PMID:
29763804
11.

2-Aryl benzimidazoles: Synthesis, In vitro α-amylase inhibitory activity, and molecular docking study.

Adegboye AA, Khan KM, Salar U, Aboaba SA, Kanwal, Chigurupati S, Fatima I, Taha M, Wadood A, Mohammad JI, Khan H, Perveen S.

Eur J Med Chem. 2018 Apr 25;150:248-260. doi: 10.1016/j.ejmech.2018.03.011. Epub 2018 Mar 6.

PMID:
29533872
12.

Combination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke.

Chen X, Arumugam TV, Cheng YL, Lee JH, Chigurupati S, Mattson MP, Basta M.

Neuromolecular Med. 2018 Mar;20(1):63-72. doi: 10.1007/s12017-017-8474-6. Epub 2018 Jan 3.

13.

New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers.

Salar U, Khan KM, Chigurupati S, Taha M, Wadood A, Vijayabalan S, Ghufran M, Perveen S.

Sci Rep. 2017 Dec 5;7(1):16980. doi: 10.1038/s41598-017-17261-w.

14.

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study.

Taha M, Irshad M, Imran S, Chigurupati S, Selvaraj M, Rahim F, Ismail NH, Nawaz F, Khan KM.

Eur J Med Chem. 2017 Dec 1;141:530-537. doi: 10.1016/j.ejmech.2017.10.028. Epub 2017 Oct 12.

PMID:
29102178
15.

In vitro antioxidant and in vivo antidepressant activity of green synthesized azomethine derivatives of cinnamaldehyde.

Chigurupati S, Shaikh SA, Mohammad JI, Selvarajan KK, Nemala AR, Khaw CH, Teoh CF, Kee TH.

Indian J Pharmacol. 2017 May-Jun;49(3):229-235. doi: 10.4103/ijp.IJP_293_16.

16.

Synthesis and in vitro study of benzofuran hydrazone derivatives as novel alpha-amylase inhibitor.

Taha M, Shah SAA, Imran S, Afifi M, Chigurupati S, Selvaraj M, Rahim F, Ullah H, Zaman K, Vijayabalan S.

Bioorg Chem. 2017 Dec;75:78-85. doi: 10.1016/j.bioorg.2017.09.002. Epub 2017 Sep 7.

PMID:
28918064
17.

Synthesis and study of the α-amylase inhibitory potential of thiadiazole quinoline derivatives.

Taha M, Tariq Javid M, Imran S, Selvaraj M, Chigurupati S, Ullah H, Rahim F, Khan F, Islam Mohammad J, Mohammed Khan K.

Bioorg Chem. 2017 Oct;74:179-186. doi: 10.1016/j.bioorg.2017.08.003. Epub 2017 Aug 12.

PMID:
28826047
18.

Biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl ether derivatives, in vitro α-amylase inhibitory activity and in silico studies.

Taha M, Imran S, Ismail NH, Selvaraj M, Rahim F, Chigurupati S, Ullah H, Khan F, Salar U, Javid MT, Vijayabalan S, Zaman K, Khan KM.

Bioorg Chem. 2017 Oct;74:1-9. doi: 10.1016/j.bioorg.2017.07.001. Epub 2017 Jul 11.

PMID:
28719801
19.

Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor.

Imran S, Taha M, Selvaraj M, Ismail NH, Chigurupati S, Mohammad JI.

Bioorg Chem. 2017 Aug;73:121-127. doi: 10.1016/j.bioorg.2017.06.007. Epub 2017 Jun 19.

PMID:
28648924
20.

Synthesis of alpha amylase inhibitors based on privileged indole scaffold.

Noreen T, Taha M, Imran S, Chigurupati S, Rahim F, Selvaraj M, Ismail NH, Mohammad JI, Ullah H, Javid MT, Nawaz F, Irshad M, Ali M.

Bioorg Chem. 2017 Jun;72:248-255. doi: 10.1016/j.bioorg.2017.04.010. Epub 2017 Apr 21.

PMID:
28482265
21.

Correction: TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.

Sulak M, Fong L, Mika K, Chigurupati S, Yon L, Mongan NP, Emes RD, Lynch VJ.

Elife. 2016 Dec 20;5. pii: e24307. doi: 10.7554/eLife.24307. No abstract available.

22.

Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer.

Bera H, Chigurupati S.

Eur J Med Chem. 2016 Nov 29;124:992-1003. doi: 10.1016/j.ejmech.2016.10.032. Epub 2016 Oct 17. Review.

PMID:
27783978
23.

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.

Sulak M, Fong L, Mika K, Chigurupati S, Yon L, Mongan NP, Emes RD, Lynch VJ.

Elife. 2016 Sep 19;5. pii: e11994. doi: 10.7554/eLife.11994. Erratum in: Elife. 2016 Dec 20;5:.

24.

Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies.

Chigurupati S, Selvaraj M, Mani V, Selvarajan KK, Mohammad JI, Kaveti B, Bera H, Palanimuthu VR, Teh LK, Salleh MZ.

Bioorg Chem. 2016 Aug;67:9-17. doi: 10.1016/j.bioorg.2016.05.002. Epub 2016 May 13.

PMID:
27231830
25.

Corrigendum to "Combination therapy with lenalidomide and nanoceria ameliorates CNS autoimmunity", [Exp. Neurol. 273 (2015), 151-160].

Eitan E, Hutchison ER, Greig NH, Tweedie D, Celik H, Ghosh S, Fishbein KW, Spencer RG, Sasaki CY, Ghosh P, Das S, Chigurapati S, Raymick J, Sarkar S, Chigurupati S, Seal S, Mattson MP.

Exp Neurol. 2016 Jun;280:121. doi: 10.1016/j.expneurol.2016.02.015. Epub 2016 Apr 4. No abstract available.

26.

A Simple HPLC-UV Method for the Determination of Glutathione in PC-12 Cells.

Appala RN, Chigurupati S, Appala RV, Krishnan Selvarajan K, Islam Mohammad J.

Scientifica (Cairo). 2016;2016:6897890. doi: 10.1155/2016/6897890. Epub 2016 Apr 4.

27.

The role of adiponectin in obesity-associated female-specific carcinogenesis.

Nagaraju GP, Rajitha B, Aliya S, Kotipatruni RP, Madanraj AS, Hammond A, Park D, Chigurupati S, Alam A, Pattnaik S.

Cytokine Growth Factor Rev. 2016 Oct;31:37-48. doi: 10.1016/j.cytogfr.2016.03.014. Epub 2016 Apr 6. Review.

PMID:
27079372
28.

Combination therapy with lenalidomide and nanoceria ameliorates CNS autoimmunity.

Eitan E, Hutchison ER, Greig NH, Tweedie D, Celik H, Ghosh S, Fishbein KW, Spencer RG, Sasaki CY, Ghosh P, Das S, Chigurapati S, Raymick J, Sarkar S, Chigurupati S, Seal S, Mattson MP.

Exp Neurol. 2015 Nov;273:151-60. doi: 10.1016/j.expneurol.2015.08.008. Epub 2015 Aug 13.

29.

A step ahead of PPARγ full agonists to PPARγ partial agonists: therapeutic perspectives in the management of diabetic insulin resistance.

Chigurupati S, Dhanaraj SA, Balakumar P.

Eur J Pharmacol. 2015 May 15;755:50-7. doi: 10.1016/j.ejphar.2015.02.043. Epub 2015 Mar 5. Review.

PMID:
25748601
30.

DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.

Sykora P, Misiak M, Wang Y, Ghosh S, Leandro GS, Liu D, Tian J, Baptiste BA, Cong WN, Brenerman BM, Fang E, Becker KG, Hamilton RJ, Chigurupati S, Zhang Y, Egan JM, Croteau DL, Wilson DM 3rd, Mattson MP, Bohr VA.

Nucleic Acids Res. 2015 Jan;43(2):943-59. doi: 10.1093/nar/gku1356. Epub 2014 Dec 30.

31.

The use of MRI to assist the section selections for classical pathology assessment of neurotoxicity.

Hanig J, Paule MG, Ramu J, Schmued L, Konak T, Chigurupati S, Slikker W Jr, Sarkar S, Liachenko S.

Regul Toxicol Pharmacol. 2014 Dec;70(3):641-7. doi: 10.1016/j.yrtph.2014.09.010. Epub 2014 Sep 28.

PMID:
25265367
32.

Neuroprotective effect of the chemical chaperone, trehalose in a chronic MPTP-induced Parkinson's disease mouse model.

Sarkar S, Chigurupati S, Raymick J, Mann D, Bowyer JF, Schmitt T, Beger RD, Hanig JP, Schmued LC, Paule MG.

Neurotoxicology. 2014 Sep;44:250-62. doi: 10.1016/j.neuro.2014.07.006. Epub 2014 Jul 23.

PMID:
25064079
33.

Functional and structural analysis of mice TRPC6 with human analogue through homology modelling.

Chigurupati S, Bhasin A, Inampudi KK, Asuthkar S, Madarampalli B, Kammili RK, Velpula KK.

Int J Bioinform Res Appl. 2014;10(2):206-16. doi: 10.1504/IJBRA.2014.059536.

PMID:
24589838
34.

Neurovascular changes in acute, sub-acute and chronic mouse models of Parkinson's disease.

Sarkar S, Raymick J, Mann D, Bowyer JF, Hanig JP, Schmued LC, Paule MG, Chigurupati S.

Curr Neurovasc Res. 2014 Feb;11(1):48-61.

PMID:
24274908
35.

Targeting DUSPs in glioblastomas - wielding a double-edged sword?

Prabhakar S, Asuthkar S, Lee W, Chigurupati S, Zakharian E, Tsung AJ, Velpula KK.

Cell Biol Int. 2014 Feb;38(2):145-53. doi: 10.1002/cbin.10201. Epub 2013 Nov 18. Review.

PMID:
24155099
36.

Another surprise from Metformin: novel mechanism of action via K-Ras influences endometrial cancer response to therapy.

Iglesias DA, Yates MS, van der Hoeven D, Rodkey TL, Zhang Q, Co NN, Burzawa J, Chigurupati S, Celestino J, Bowser J, Broaddus R, Hancock JF, Schmandt R, Lu KH.

Mol Cancer Ther. 2013 Dec;12(12):2847-56. doi: 10.1158/1535-7163.MCT-13-0439. Epub 2013 Sep 27.

37.

3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation.

Yoon JS, Lee JH, Tweedie D, Mughal MR, Chigurupati S, Greig NH, Mattson MP.

J Neurosci Res. 2013 May;91(5):671-80. doi: 10.1002/jnr.23190. Epub 2013 Feb 13.

38.

Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing.

Chigurupati S, Mughal MR, Okun E, Das S, Kumar A, McCaffery M, Seal S, Mattson MP.

Biomaterials. 2013 Mar;34(9):2194-201. doi: 10.1016/j.biomaterials.2012.11.061. Epub 2012 Dec 23.

39.

Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission.

van der Hoeven D, Cho KJ, Ma X, Chigurupati S, Parton RG, Hancock JF.

Mol Cell Biol. 2013 Jan;33(2):237-51. doi: 10.1128/MCB.00884-12. Epub 2012 Nov 5.

40.

Computational analysis of human and mouse CREB3L4 Protein.

Velpula KK, Rehman AA, Chigurupati S, Sanam R, Inampudi KK, Akila CS.

Bioinformation. 2012;8(12):574-7. doi: 10.6026/97320630008574. Epub 2012 Jun 28.

41.

Raf inhibitors target ras spatiotemporal dynamics.

Cho KJ, Kasai RS, Park JH, Chigurupati S, Heidorn SJ, van der Hoeven D, Plowman SJ, Kusumi A, Marais R, Hancock JF.

Curr Biol. 2012 Jun 5;22(11):945-55. doi: 10.1016/j.cub.2012.03.067. Epub 2012 May 3.

42.

Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.

Li Y, Chigurupati S, Holloway HW, Mughal M, Tweedie D, Bruestle DA, Mattson MP, Wang Y, Harvey BK, Ray B, Lahiri DK, Greig NH.

PLoS One. 2012;7(2):e32008. doi: 10.1371/journal.pone.0032008. Epub 2012 Feb 23.

43.

DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.

Olkhanud PB, Mughal M, Ayukawa K, Malchinkhuu E, Bodogai M, Feldman N, Rothman S, Lee JH, Chigurupati S, Okun E, Nagashima K, Mattson MP, Biragyn A.

Vaccine. 2012 Feb 21;30(9):1650-8. doi: 10.1016/j.vaccine.2011.12.136. Epub 2012 Jan 14.

44.

Effect of acetazolamide on aquaporin-1 and fluid flow in cultured choroid plexus.

Ameli PA, Madan M, Chigurupati S, Yu A, Chan SL, Pattisapu JV.

Acta Neurochir Suppl. 2012;113:59-64. doi: 10.1007/978-3-7091-0923-6_13.

PMID:
22116425
45.

Chronic nicotine administration impairs activation of cyclic AMP-response element binding protein and survival of newborn cells in the dentate gyrus.

Wei Z, Belal C, Tu W, Chigurupati S, Ameli NJ, Lu Y, Chan SL.

Stem Cells Dev. 2012 Feb 10;21(3):411-22. doi: 10.1089/scd.2010.0326. Epub 2011 Aug 29.

PMID:
21740234
46.

Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia.

Wei Z, Chigurupati S, Arumugam TV, Jo DG, Li H, Chan SL.

Stroke. 2011 Sep;42(9):2589-94. doi: 10.1161/STROKEAHA.111.614834. Epub 2011 Jul 7.

PMID:
21737799
47.

Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy.

Sopko N, Qin Y, Finan A, Dadabayev A, Chigurupati S, Qin J, Penn MS, Gupta S.

PLoS One. 2011;6(5):e20184. doi: 10.1371/journal.pone.0020184. Epub 2011 May 19.

48.

Evidence for altered Numb isoform levels in Alzheimer's disease patients and a triple transgenic mouse model.

Chigurupati S, Madan M, Okun E, Wei Z, Pattisapu JV, Mughal MR, Mattson MP, Chan SL.

J Alzheimers Dis. 2011;24(2):349-61. doi: 10.3233/JAD-2011-101797.

PMID:
21258150
49.

Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.

Cho KJ, Hill MM, Chigurupati S, Du G, Parton RG, Hancock JF.

Mol Cell Biol. 2011 Mar;31(6):1110-20. doi: 10.1128/MCB.00989-10. Epub 2011 Jan 18.

50.

Expression of aquaporin 1 and 4 in a congenital hydrocephalus rat model.

Paul L, Madan M, Rammling M, Chigurupati S, Chan SL, Pattisapu JV.

Neurosurgery. 2011 Feb;68(2):462-73. doi: 10.1227/NEU.0b013e3182011860.

PMID:
21135737

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