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Editorial overview: Prion disease: From drug discovery tools to clinical trials.

Chiesa R, Vorberg IM.

Curr Opin Pharmacol. 2019 Feb;44:iii-v. doi: 10.1016/j.coph.2019.05.002. No abstract available.


A Rotational Thromboelastometry Driven Transfusion Strategy Reduces Allogenic Blood Transfusion During Open Thoraco-abdominal Aortic Aneurysm Repair: A Propensity Score Matched Study.

Monaco F, Barucco G, Nardelli P, Licheri M, Notte C, De Luca M, Mattioli C, Melissano G, Chiesa R, Zangrillo A.

Eur J Vasc Endovasc Surg. 2019 Jun 8. pii: S1078-5884(19)30106-6. doi: 10.1016/j.ejvs.2019.02.009. [Epub ahead of print]


Cyclophillin A deficiency accelerates RML-induced prion disease.

Bouybayoune I, Comerio L, Pasetto L, Bertani I, Bonetto V, Chiesa R.

Neurobiol Dis. 2019 Jun 7:104498. doi: 10.1016/j.nbd.2019.104498. [Epub ahead of print]


Age at onset in genetic prion disease and the design of preventive clinical trials.

Minikel EV, Vallabh SM, Orseth MC, Brandel JP, Haïk S, Laplanche JL, Zerr I, Parchi P, Capellari S, Safar J, Kenny J, Fong JC, Takada LT, Ponto C, Hermann P, Knipper T, Stehmann C, Kitamoto T, Ae R, Hamaguchi T, Sanjo N, Tsukamoto T, Mizusawa H, Collins SJ, Chiesa R, Roiter I, de Pedro-Cuesta J, Calero M, Geschwind MD, Yamada M, Nakamura Y, Mead S.

Neurology. 2019 Jun 6. pii: 10.1212/WNL.0000000000007745. doi: 10.1212/WNL.0000000000007745. [Epub ahead of print]


Five-year results from the Study of Thoracic Aortic Type B Dissection Using Endoluminal Repair (STABLE I) study of endovascular treatment of complicated type B aortic dissection using a composite device design.

Lombardi JV, Cambria RP, Nienaber CA, Chiesa R, Mossop P, Haulon S, Zhou Q; STABLE I Investigators.

J Vasc Surg. 2019 May 27. pii: S0741-5214(19)30401-X. doi: 10.1016/j.jvs.2019.01.089. [Epub ahead of print]


Progression of brain white matter hyperintensities in asymptomatic patients with carotid atherosclerotic plaques and no indication for revascularization.

Ammirati E, Moroni F, Magnoni M, Rocca MA, Anzalone N, Cacciaguerra L, Di Terlizzi S, Villa C, Sizzano F, Palini A, Scotti I, Besana F, Spagnolo P, Rimoldi OE, Chiesa R, Falini A, Filippi M, Camici PG.

Atherosclerosis. 2019 May 6. pii: S0021-9150(19)30405-8. doi: 10.1016/j.atherosclerosis.2019.04.230. [Epub ahead of print]


Preliminary results of debranch-first technique in Frozen Elephant Trunk procedures.

Bertoglio L, Fittipaldi A, Giambuzzi I, Redaelli P, Verzini A, Cambiaghi T, Bargagna M, Alfieri O, Chiesa R, Castiglioni A.

Ann Thorac Surg. 2019 May 10. pii: S0003-4975(19)30680-0. doi: 10.1016/j.athoracsur.2019.04.010. [Epub ahead of print]


Coping With Negative Stereotypes Toward Older Workers: Organizational and Work-Related Outcomes.

Chiesa R, Zaniboni S, Guglielmi D, Vignoli M.

Front Psychol. 2019 Mar 22;10:649. doi: 10.3389/fpsyg.2019.00649. eCollection 2019.


Improving Safety through Non-Technical Skills in Chemical Plants: The Validity of a Questionnaire for the Self-Assessment of Workers.

Mariani MG, Vignoli M, Chiesa R, Violante FS, Guglielmi D.

Int J Environ Res Public Health. 2019 Mar 19;16(6). pii: E992. doi: 10.3390/ijerph16060992.


Experimental models to study prion disease pathogenesis and identify potential therapeutic compounds.

Vorberg I, Chiesa R.

Curr Opin Pharmacol. 2019 Feb;44:28-38. doi: 10.1016/j.coph.2019.02.002. Epub 2019 Mar 14. Review.


Laser versus LED polymerization: Comparison of in vitro preventive sealing procedures.

Mastrangelo F, Perraro I, Mattia S, Troiano G, Zhurakivska K, Polizzi E, Chiesa R, Gherlone E, Lo Muzio L.

J Appl Biomater Funct Mater. 2019 Jan-Mar;17(1):2280800018816013. doi: 10.1177/2280800018816013.


New technical approach for type B dissection: from the PETTICOAT to the STABILISE concept.

Kahlberg A, Mascia D, Bertoglio L, Loschi D, Grandi A, Melissano G, Chiesa R.

J Cardiovasc Surg (Torino). 2019 Jun;60(3):281-288. doi: 10.23736/S0021-9509.19.10904-4. Epub 2019 Feb 20. Review.


New graft manipulation strategies improve the outcome of mismatched stem cell transplantation in children with primary immunodeficiencies.

Elfeky R, Shah RM, Unni MNM, Ottaviano G, Rao K, Chiesa R, Amrolia P, Worth A, Flood T, Abinun M, Hambleton S, Cant AJ, Gilmour K, Adams S, Ahsan G, Barge D, Gennery AR, Qasim W, Slatter M, Veys P.

J Allergy Clin Immunol. 2019 Feb 4. pii: S0091-6749(19)30187-3. doi: 10.1016/j.jaci.2019.01.030. [Epub ahead of print]


Clinical Cases Referring to Diagnosis and Management of Patients With Thoracic Aortic Pathologies Involving the Aortic Arch: A Companion Document of the 2018 European Association for Cardio-Thoracic Surgery (EACTS) and the European Society for Vascular Surgery (ESVS) Expert Consensus Document Addressing Current Options and Recommendations for the Treatment of Thoracic Aortic Pathologies Involving the Aortic Arch.

Czerny M, Schmidli J, Bertoglio L, Carrel T, Chiesa R, Clough RE, Grabenwöger M, Kari FA, Mestres CA, Rylski B, Schönhoff F, Tsagakis K, Wyss TR.

Eur J Vasc Endovasc Surg. 2019 Mar;57(3):452-460. doi: 10.1016/j.ejvs.2018.12.011. Epub 2019 Jan 18. Review. No abstract available.


Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation.

Ottaviano G, Chiesa R, Feuchtinger T, Vickers MA, Dickinson A, Gennery AR, Veys P, Todryk S.

Cells. 2019 Jan 14;8(1). pii: E47. doi: 10.3390/cells8010047. Review.


Review: PrP 106-126 - 25 years after.

Forloni G, Chiesa R, Bugiani O, Salmona M, Tagliavini F.

Neuropathol Appl Neurobiol. 2019 Jan 12. doi: 10.1111/nan.12538. [Epub ahead of print] Review.


Surgical transaxillary placement of the Impella 5.0 ventricular assist device.

Bertoglio L, Katsarou M, Scandroglio M, Bertoldi L, Chiesa R, Pappalardo F.

J Card Surg. 2019 Feb;34(2):92-98. doi: 10.1111/jocs.13978. Epub 2019 Jan 9.


A systematic review of infected descending thoracic aortic grafts and endografts.

Kahlberg A, Grandi A, Loschi D, Vermassen F, Moreels N, Chakfé N, Melissano G, Chiesa R.

J Vasc Surg. 2019 Jun;69(6):1941-1951.e1. doi: 10.1016/j.jvs.2018.10.108. Epub 2019 Jan 1. Review.


Cellular prion protein neither binds to alpha-synuclein oligomers nor mediates their detrimental effects.

La Vitola P, Beeg M, Balducci C, Santamaria G, Restelli E, Colombo L, Caldinelli L, Pollegioni L, Gobbi M, Chiesa R, Forloni G.

Brain. 2019 Feb 1;142(2):249-254. doi: 10.1093/brain/awy318.


IL-1β/MMP9 activation in primary human vascular smooth muscle-like cells: Exploring the role of TNFα and P2X7.

Mantione ME, Lombardi M, Baccellieri D, Ferrara D, Castellano R, Chiesa R, Alfieri O, Foglieni C.

Int J Cardiol. 2019 Mar 1;278:202-209. doi: 10.1016/j.ijcard.2018.12.047. Epub 2018 Dec 18.


Correction to: Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children.

Boonsathorn S, Cheng I, Kloprogge F, Alonso C, Lee C, Doncheva B, Booth J, Chiesa R, Irwin A, Standing JF.

Clin Pharmacokinet. 2019 Jan;58(1):141. doi: 10.1007/s40262-018-0722-x.


Neuroprotective modulation of the unfolded protein response in Marinesco-Sjögren syndrome: PERK signaling inhibition and beyond.

Restelli E, Masone A, Sallese M, Chiesa R.

Neural Regen Res. 2019 Jan;14(1):62-64. doi: 10.4103/1673-5374.243708. No abstract available.


True Lumen Stabilization to Overcome Malperfusion in Acute Type I Aortic Dissection.

Tsagakis K, Jánosi RA, Frey UH, Schlosser T, Chiesa R, Rassaf T, Jakob H.

Semin Thorac Cardiovasc Surg. 2018 Dec 8. pii: S1043-0679(18)30385-X. doi: 10.1053/j.semtcvs.2018.11.012. [Epub ahead of print]


Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation.

Gkazi AS, Margetts BK, Attenborough T, Mhaldien L, Standing JF, Oakes T, Heather JM, Booth J, Pasquet M, Chiesa R, Veys P, Klein N, Chain B, Callard R, Adams SP.

Front Immunol. 2018 Nov 5;9:2547. doi: 10.3389/fimmu.2018.02547. eCollection 2018.


Epidural Analgesia in Open Thoraco-abdominal Aortic Aneurysm Repair.

Monaco F, Pieri M, Barucco G, Karpatri V, Redaelli MB, De Luca M, Mattioli C, Bove T, Melissano G, Chiesa R, Landoni G, Zangrillo A.

Eur J Vasc Endovasc Surg. 2019 Mar;57(3):360-367. doi: 10.1016/j.ejvs.2018.09.027. Epub 2018 Oct 29.


Bactericidal activity of gallium-doped chitosan coatings against staphylococcal infection.

Ghalayani Esfahani A, Lazazzera B, Draghi L, Farè S, Chiesa R, De Nardo L, Billi F.

J Appl Microbiol. 2019 Jan;126(1):87-101. doi: 10.1111/jam.14133. Epub 2018 Nov 20.


Editor's Choice - Current Options and Recommendations for the Treatment of Thoracic Aortic Pathologies Involving the Aortic Arch: An Expert Consensus Document of the European Association for Cardio-Thoracic Surgery (EACTS) & the European Society for Vascular Surgery (ESVS).

Czerny M, Schmidli J, Adler S, van den Berg JC, Bertoglio L, Carrel T, Chiesa R, Clough RE, Eberle B, Etz C, Grabenwöger M, Haulon S, Jakob H, Kari FA, Mestres CA, Pacini D, Resch T, Rylski B, Schoenhoff F, Shrestha M, von Tengg-Kobligk H, Tsagakis K, Wyss TR, Document Reviewers, Chakfe N, Debus S, de Borst GJ, Di Bartolomeo R, Lindholt JS, Ma WG, Suwalski P, Vermassen F, Wahba A, Wyler von Ballmoos MC.

Eur J Vasc Endovasc Surg. 2019 Feb;57(2):165-198. doi: 10.1016/j.ejvs.2018.09.016. Epub 2018 Oct 12. No abstract available.


Current options and recommendations for the treatment of thoracic aortic pathologies involving the aortic arch: an expert consensus document of the European Association for Cardio-Thoracic surgery (EACTS) and the European Society for Vascular Surgery (ESVS).

Czerny M, Schmidli J, Adler S, van den Berg JC, Bertoglio L, Carrel T, Chiesa R, Clough RE, Eberle B, Etz C, Grabenwöger M, Haulon S, Jakob H, Kari FA, Mestres CA, Pacini D, Resch T, Rylski B, Schoenhoff F, Shrestha M, von Tengg-Kobligk H, Tsagakis K, Wyss TR; EACTS/ESVS scientific document group.

Eur J Cardiothorac Surg. 2019 Jan 1;55(1):133-162. doi: 10.1093/ejcts/ezy313. No abstract available.


PERK inhibition attenuates the abnormalities of the secretory pathway and the increased apoptotic rate induced by SIL1 knockdown in HeLa cells.

Capone V, Clemente E, Restelli E, Di Campli A, Sperduti S, Ornaghi F, Pietrangelo L, Protasi F, Chiesa R, Sallese M.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3164-3180. doi: 10.1016/j.bbadis.2018.07.003. Epub 2018 Jul 7.


Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis.

Lucchini G, Marsh R, Gilmour K, Worth A, Nademi Z, Rao A, Booth C, Amrolia P, Silva J, Chiesa R, Wynn R, Lehmberg K, Astigarraga I, Güngör T, Stary J, Moshous D, Ifversen M, Zinn D, Jordan M, Kumar A, Yasumi T, Veys P, Rao K.

Blood. 2018 Nov 8;132(19):2088-2096. doi: 10.1182/blood-2018-01-827485. Epub 2018 Aug 13.


Induction of a transmissible tau pathology by traumatic brain injury.

Zanier ER, Bertani I, Sammali E, Pischiutta F, Chiaravalloti MA, Vegliante G, Masone A, Corbelli A, Smith DH, Menon DK, Stocchetti N, Fiordaliso F, De Simoni MG, Stewart W, Chiesa R.

Brain. 2018 Sep 1;141(9):2685-2699. doi: 10.1093/brain/awy193.


Covered stenting and transcatheter embolization of splenic artery aneurysms in diabetic patients: A review of endovascular treatment of visceral artery aneurysms in the current era.

Venturini M, Marra P, Colarieti A, Agostini G, Lanza C, Augello L, Gusmini S, Salvioni M, Melissano G, Fiorina P, Chiesa R, De Cobelli F, Del Maschio A.

Pharmacol Res. 2018 Sep;135:127-135. doi: 10.1016/j.phrs.2018.07.023. Epub 2018 Jul 25. Review.


One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years.

Elfeky RA, Furtado-Silva JM, Chiesa R, Rao K, Amrolia P, Lucchini G, Gilmour K, Adams S, Bibi S, Worth A, Thrasher AJ, Qasim W, Veys P.

J Allergy Clin Immunol. 2018 Nov;142(5):1654-1656.e7. doi: 10.1016/j.jaci.2018.06.042. Epub 2018 Jul 25. No abstract available.


Reparo aberto de aneurisma de aorta toracoabdominal: atualização da abordagem multimodal.

Chiesa R, Melissano G, Rinaldi E.

J Vasc Bras. 2017 Jul-Sep;16(3):183-186. doi: 10.1590/1677-5449.071317. Portuguese. No abstract available.

Free PMC Article

Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation.

Ip W, Silva JMF, Gaspar H, Mitra A, Patel S, Rao K, Chiesa R, Amrolia P, Gilmour K, Ahsan G, Slatter M, Gennery AR, Wynn RF, Veys P, Qasim W.

Cytotherapy. 2018 Jun;20(6):830-838. doi: 10.1016/j.jcyt.2018.03.040. Epub 2018 May 9.


Left Ventricular Assist Device Outflow Conduit Fissuration: Endovascular Salvage.

Bertoglio L, Cambiaghi T, Pappalardo F, De Bonis M, Castiglioni A, Chiesa R.

JACC Cardiovasc Interv. 2018 May 28;11(10):1009-1010. doi: 10.1016/j.jcin.2018.02.012. Epub 2018 May 2. No abstract available.


PERK inhibition delays neurodegeneration and improves motor function in a mouse model of Marinesco-Sjögren syndrome.

Grande V, Ornaghi F, Comerio L, Restelli E, Masone A, Corbelli A, Tolomeo D, Capone V, Axten JM, Laping NJ, Fiordaliso F, Sallese M, Chiesa R.

Hum Mol Genet. 2018 Jul 15;27(14):2477-2489. doi: 10.1093/hmg/ddy152.


Management of visceral aortic patch aneurysms after thoracoabdominal repair with open, hybrid, or endovascular approach.

Bertoglio L, Mascia D, Cambiaghi T, Kahlberg A, Tshomba Y, Gomez JC, Melissano G, Chiesa R.

J Vasc Surg. 2018 May;67(5):1360-1371. doi: 10.1016/j.jvs.2017.09.024.


Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children.

Boonsathorn S, Cheng I, Kloprogge F, Alonso C, Lee C, Doncheva B, Booth J, Chiesa R, Irwin A, Standing JF.

Clin Pharmacokinet. 2019 Jan;58(1):53-61. doi: 10.1007/s40262-018-0658-1. Erratum in: Clin Pharmacokinet. 2018 Dec 17;:.


Allogeneic hematopoietic stem cell transplantation for severe, refractory juvenile idiopathic arthritis.

M F Silva J, Ladomenou F, Carpenter B, Chandra S, Sedlacek P, Formankova R, Grandage V, Friswell M, Cant AJ, Nademi Z, Slatter MA, Gennery AR, Hambleton S, Flood TJ, Lucchini G, Chiesa R, Rao K, Amrolia PJ, Brogan P, Wedderburn LR, Glanville JM, Hough R, Marsh R, Abinun M, Veys P.

Blood Adv. 2018 Apr 10;2(7):777-786. doi: 10.1182/bloodadvances.2017014449.


Satisfactory short-term outcomes of the STABILISE technique for type B aortic dissection.

Melissano G, Bertoglio L, Rinaldi E, Mascia D, Kahlberg A, Loschi D, De Luca M, Monaco F, Chiesa R.

J Vasc Surg. 2018 Oct;68(4):966-975. doi: 10.1016/j.jvs.2018.01.029. Epub 2018 Mar 30.


Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience.

Unni MNM, Elfeky R, Rao K, Nademi Z, Chiesa R, Amrolia P, Skinner R, Slater O, Worth A, Flood T, Abinun M, Hambleton S, Qasim W, Gaspar HB, Cant AJ, Gennery AR, Veys P, Slatter MA.

J Allergy Clin Immunol. 2018 Jun;141(6):2319-2321.e1. doi: 10.1016/j.jaci.2018.02.038. Epub 2018 Mar 7. No abstract available.


Relationship between Syntax Score and prognostic localization of coronary artery lesions with conventional risk factors, plasma profile markers, and carotid atherosclerosis (CAPP Study 2).

Cappelletti A, Astore D, Godino C, Bellini B, Magni V, Mazzavillani M, Pagnesi M, Agricola E, Chiesa R, Colombo A, Margonato A.

Int J Cardiol. 2018 Apr 15;257:306-311. doi: 10.1016/j.ijcard.2017.12.012.


Percutaneous axillary artery access for fenestrated and branched thoracoabdominal endovascular repair.

Bertoglio L, Mascia D, Cambiaghi T, Kahlberg A, Melissano G, Chiesa R.

J Vasc Surg. 2018 Jul;68(1):12-23. doi: 10.1016/j.jvs.2017.09.053. Epub 2018 Mar 1.


Reentry Devices for Lamella Neofenestration During Endovascular Aortic Repair of Chronic Type B Aortic Dissection.

Bertoglio L, Cambiaghi T, Grandi A, Kahlberg A, Melissano G, Chiesa R.

J Endovasc Ther. 2018 Apr;25(2):242-246. doi: 10.1177/1526602818759756. Epub 2018 Feb 21.


Current treatment of superficial femoral artery disease: a national survey.

Marone EM, Rinaldi LF, Argenteri A, Chiesa R.

J Cardiovasc Surg (Torino). 2018 Oct;59(5):755-756. doi: 10.23736/S0021-9509.18.10334-X. Epub 2018 Feb 8. No abstract available.


Use of Defibrotide to help prevent post-transplant endothelial injury in a genetically predisposed infant with metachromatic leukodystrophy undergoing hematopoietic stem cell gene therapy.

Calbi V, Fumagalli F, Consiglieri G, Penati R, Acquati S, Redaelli D, Attanasio V, Marcella F, Cicalese MP, Migliavacca M, Barzaghi F, Ferrua F, Assanelli A, Silvani P, Zoccolillo M, Chidini G, Chiesa R, Arora R, Ciotti F, Sarzana M, Antonioli G, Baldoli C, Morena F, Martino S, Ardissino GL, Sora MGN, Naldini L, Ciceri F, Aiuti A, Bernardo ME.

Bone Marrow Transplant. 2018 Jul;53(7):913-917. doi: 10.1038/s41409-017-0085-1. Epub 2018 Jan 29. No abstract available.


Umbilical cord blood transplantation without in vivo T-cell depletion for children with MHC class II deficiency.

Elfeky R, Furtado-Silva JM, Chiesa R, Rao K, Lucchini G, Amrolia P, Worth A, Gaspar B, Qasim W, Veys P.

J Allergy Clin Immunol. 2018 Jun;141(6):2279-2282.e2. doi: 10.1016/j.jaci.2017.10.051. Epub 2018 Jan 31. No abstract available.


Preliminary Outcomes of the LifeStream Balloon-Expandable Covered Stent in Fenestrated and Branched Thoracoabdominal Endovascular Repairs.

Bertoglio L, Loschi D, Cambiaghi T, Mascia D, Kahlberg A, Melissano G, Chiesa R.

J Endovasc Ther. 2018 Apr;25(2):230-236. doi: 10.1177/1526602817752449. Epub 2018 Jan 9.


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