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Items: 19


Dental implant bioactive surface modifications and their effects on osseointegration: a review.

Meng HW, Chien EY, Chien HH.

Biomark Res. 2016 Dec 14;4:24. doi: 10.1186/s40364-016-0078-z. eCollection 2016. Review.


Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR.

Structure. 2011 Oct 12;19(10):1424-32. doi: 10.1016/j.str.2011.08.001. Epub 2011 Sep 1.


Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.

Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC.

Science. 2010 Nov 19;330(6007):1091-5. doi: 10.1126/science.1197410.


Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.

Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC.

Science. 2010 Nov 19;330(6007):1066-71. doi: 10.1126/science.1194396. Epub 2010 Oct 7.


Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.

Zhang X, Chien EY, Chalmers MJ, Pascal BD, Gatchalian J, Stevens RC, Griffin PR.

Anal Chem. 2010 Feb 1;82(3):1100-8. doi: 10.1021/ac902484p.


The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC.

Science. 2008 Nov 21;322(5905):1211-7. doi: 10.1126/science.1164772. Epub 2008 Oct 2.


A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.

Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC.

Structure. 2008 Jun;16(6):897-905. doi: 10.1016/j.str.2008.05.001.


Microscale fluorescent thermal stability assay for membrane proteins.

Alexandrov AI, Mileni M, Chien EY, Hanson MA, Stevens RC.

Structure. 2008 Mar;16(3):351-9. doi: 10.1016/j.str.2008.02.004.


Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression.

Hanson MA, Brooun A, Baker KA, Jaakola VP, Roth C, Chien EY, Alexandrov A, Velasquez J, Davis L, Griffith M, Moy K, Ganser-Pornillos BK, Hua Y, Kuhn P, Ellis S, Yeager M, Stevens RC.

Protein Expr Purif. 2007 Nov;56(1):85-92. Epub 2007 Jun 27.


Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex.

Brooun A, Foster SA, Chrencik JE, Chien EY, Kolatkar AR, Streiff M, Ramage P, Widmer H, Weckbecker G, Kuhn P.

Protein Expr Purif. 2007 May;53(1):51-62. Epub 2006 Dec 5.


Spatial analysis of childhood leukemia in a case/control study.

Selvin S, Ragland KE, Chien EY, Buffler PA.

Int J Hyg Environ Health. 2004 Dec;207(6):555-62.


Structure of a c-kit product complex reveals the basis for kinase transactivation.

Mol CD, Lim KB, Sridhar V, Zou H, Chien EY, Sang BC, Nowakowski J, Kassel DB, Cronin CN, McRee DE.

J Biol Chem. 2003 Aug 22;278(34):31461-4. Epub 2003 Jun 24.


Connection between the taxonomic substates and protonation of histidines 64 and 97 in carbonmonoxy myoglobin.

Müller JD, McMahon BH, Chien EY, Sligar SG, Nienhaus GU.

Biophys J. 1999 Aug;77(2):1036-51.


Influence of proximal side mutations on the molecular and electronic structure of cyanomet myoglobin: an 1H NMR study.

Wu Y, Chien EY, Sligar SG, La Mar GN.

Biochemistry. 1998 May 12;37(19):6979-90.


Assignment and analysis of fluorine nuclear magnetic resonance spectra of 4-fluorotryptophan myoglobins and hemoglobins.

Pearson JG, Montez B, Le H, Oldfield E, Chien EY, Sligar SG.

Biochemistry. 1997 Mar 25;36(12):3590-9.


Ligand binding to heme proteins. V. Light-induced relaxation in proximal mutants L89I and H97F of carbonmonoxymyoglobin.

Abadan Y, Chien EY, Chu K, Eng CD, Nienhaus GU, Sligar SG.

Biophys J. 1995 Jun;68(6):2497-504.

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