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Items: 1 to 50 of 70

1.

RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain.

Wang CJ, Chidiac P.

Cell Signal. 2019 Jul;59:163-170. doi: 10.1016/j.cellsig.2019.02.007. Epub 2019 Mar 1.

PMID:
30826455
2.

Editorial overview: Musculoskeletal: New therapeutic targets and delivery systems.

Dixon SJ, Chidiac P.

Curr Opin Pharmacol. 2018 Jun;40:ix-xi. doi: 10.1016/j.coph.2018.06.002. No abstract available.

PMID:
29933940
3.

Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor.

Kim BH, Pereverzev A, Zhu S, Tong AOM, Dixon SJ, Chidiac P.

Cell Signal. 2018 Jun;46:103-112. doi: 10.1016/j.cellsig.2018.02.015. Epub 2018 Mar 1.

PMID:
29501726
4.

Maternal diabetes up-regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring.

Zhang L, Wang X, Wu Y, Lu X, Chidiac P, Wang G, Feng Q.

J Cell Mol Med. 2018 Apr;22(4):2200-2209. doi: 10.1111/jcmm.13500. Epub 2018 Jan 29.

5.

Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice.

Lee KN, Lu X, Nguyen C, Feng Q, Chidiac P.

J Mol Cell Cardiol. 2017 Jul;108:194-202. doi: 10.1016/j.yjmcc.2017.06.007. Epub 2017 Jun 19.

6.

A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains.

Narla C, Scidmore T, Jeong J, Everest M, Chidiac P, Poulter MO.

Sci Signal. 2016 Jun 14;9(432):ra60. doi: 10.1126/scisignal.aad8676.

PMID:
27303056
7.

GPCR Retreat 2014: a good view leads to many discoveries!

Chidiac P, Hébert TE.

J Recept Signal Transduct Res. 2015 Jun;35(3):208-12. doi: 10.3109/10799893.2015.1072977. Epub 2015 Sep 14.

PMID:
26366680
8.

RGS proteins destroy spare receptors: Effects of GPCR-interacting proteins and signal deamplification on measurements of GPCR agonist potency.

Chidiac P.

Methods. 2016 Jan 1;92:87-93. doi: 10.1016/j.ymeth.2015.08.011. Epub 2015 Aug 18. Review.

PMID:
26297537
9.

Regulator of G-protein signaling 2 (RGS2) suppresses premature calcium release in mouse eggs.

Bernhardt ML, Lowther KM, Padilla-Banks E, McDonough CE, Lee KN, Evsikov AV, Uliasz TF, Chidiac P, Williams CJ, Mehlmann LM.

Development. 2015 Aug 1;142(15):2633-40. doi: 10.1242/dev.121707. Epub 2015 Jul 9.

10.

Regulation of RGS5 GAP activity by GPSM3.

Zhao P, Chidiac P.

Mol Cell Biochem. 2015 Jul;405(1-2):33-40. doi: 10.1007/s11010-015-2393-3. Epub 2015 Apr 5.

PMID:
25842189
11.

G protein-coupled receptor accessory proteins and signaling: pharmacogenomic insights.

Thompson MD, Cole DE, Jose PA, Chidiac P.

Methods Mol Biol. 2014;1175:121-52. doi: 10.1007/978-1-4939-0956-8_7. Review.

PMID:
25150869
12.

The eIF2B-interacting domain of RGS2 protects against GPCR agonist-induced hypertrophy in neonatal rat cardiomyocytes.

Chidiac P, Sobiesiak AJ, Lee KN, Gros R, Nguyen CH.

Cell Signal. 2014 Jun;26(6):1226-34. doi: 10.1016/j.cellsig.2014.02.006. Epub 2014 Feb 24.

PMID:
24576550
13.

Fine-tuning of GPCR signals by intracellular G protein modulators.

Zhao P, Cladman W, Van Tol HH, Chidiac P.

Prog Mol Biol Transl Sci. 2013;115:421-53. doi: 10.1016/B978-0-12-394587-7.00010-5. Review.

PMID:
23415100
14.

GPCR Retreat 2012: timing is everything.

Chidiac P, Hébert TE.

J Recept Signal Transduct Res. 2013 Jun;33(3):129-34. doi: 10.3109/10799893.2012.759592. Epub 2013 Jan 25.

PMID:
23351073
15.

The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins.

Zhao P, Nunn C, Ramineni S, Hepler JR, Chidiac P.

J Cell Biochem. 2013 Jun;114(6):1414-23. doi: 10.1002/jcb.24483.

16.

RGS2 is a component of the cellular stress response.

Nguyen CH, Zhao P, Sobiesiak AJ, Chidiac P.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):129-34. doi: 10.1016/j.bbrc.2012.08.050. Epub 2012 Aug 17.

PMID:
22922103
17.

Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia.

Jones DL, Tuomi JM, Chidiac P.

Front Physiol. 2012 Jun 29;3:239. doi: 10.3389/fphys.2012.00239. eCollection 2012.

18.

Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia.

Zhang T, Lu X, Li J, Chidiac P, Sims SM, Feng Q.

Basic Res Cardiol. 2012 Mar;107(2):254. doi: 10.1007/s00395-012-0254-8. Epub 2012 Feb 21.

PMID:
22351078
19.

Resistance to age-related, normal body weight gain in RGS2 deficient mice.

Nunn C, Zhao P, Zou MX, Summers K, Guglielmo CG, Chidiac P.

Cell Signal. 2011 Aug;23(8):1375-86. doi: 10.1016/j.cellsig.2011.03.020. Epub 2011 Apr 5.

PMID:
21447383
20.

RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy.

Nunn C, Zou MX, Sobiesiak AJ, Roy AA, Kirshenbaum LA, Chidiac P.

Cell Signal. 2010 Aug;22(8):1231-9. doi: 10.1016/j.cellsig.2010.03.015. Epub 2010 Apr 1.

PMID:
20362664
21.

The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function.

Zhao P, Nguyen CH, Chidiac P.

J Biol Chem. 2010 Mar 19;285(12):9008-17. doi: 10.1074/jbc.M109.057174. Epub 2010 Jan 22.

22.

Evidence for enhanced M3 muscarinic receptor function and sensitivity to atrial arrhythmia in the RGS2-deficient mouse.

Tuomi JM, Chidiac P, Jones DL.

Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H554-61. doi: 10.1152/ajpheart.00779.2009. Epub 2009 Dec 4.

23.

Cardiomyocyte-specific overexpression of human stem cell factor improves cardiac function and survival after myocardial infarction in mice.

Xiang FL, Lu X, Hammoud L, Zhu P, Chidiac P, Robbins J, Feng Q.

Circulation. 2009 Sep 22;120(12):1065-74, 9 p following 1074. doi: 10.1161/CIRCULATIONAHA.108.839068. Epub 2009 Sep 8.

PMID:
19738140
24.

Translational control by RGS2.

Nguyen CH, Ming H, Zhao P, Hugendubler L, Gros R, Kimball SR, Chidiac P.

J Cell Biol. 2009 Sep 7;186(5):755-65. doi: 10.1083/jcb.200811058.

25.

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.

Aziziyeh AI, Li TT, Pape C, Pampillo M, Chidiac P, Possmayer F, Babwah AV, Bhattacharya M.

Cell Signal. 2009 Jul;21(7):1207-17. doi: 10.1016/j.cellsig.2009.03.011. Epub 2009 Mar 21.

PMID:
19306925
26.

Hippocampal long-term potentiation is enhanced in urethane-anesthetized RGS2 knockout mice.

Hutchison RM, Chidiac P, Leung LS.

Hippocampus. 2009 Aug;19(8):687-91. doi: 10.1002/hipo.20582.

PMID:
19294649
27.

Meeting review: advances from the GPCR Retreat.

Chidiac P, Hébert TE.

J Recept Signal Transduct Res. 2008;28(1-2):3-14. doi: 10.1080/10799890801941962 .

PMID:
18437626
28.

Guest editors' introduction: the beginning of a happy tradition?

Chidiac P, Hébert T.

J Recept Signal Transduct Res. 2008;28(1-2):1-2. doi: 10.1080/10799890801960541 . No abstract available.

PMID:
18437625
29.

Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system.

Wieland T, Lutz S, Chidiac P.

Curr Opin Pharmacol. 2007 Apr;7(2):201-7. Epub 2007 Feb 2. Review.

PMID:
17276730
30.

Up-regulation of endogenous RGS2 mediates cross-desensitization between Gs and Gq signaling in osteoblasts.

Roy AA, Nunn C, Ming H, Zou MX, Penninger J, Kirshenbaum LA, Dixon SJ, Chidiac P.

J Biol Chem. 2006 Oct 27;281(43):32684-93. Epub 2006 Sep 1.

31.

Modulation of subfamily B/R4 RGS protein function by 14-3-3 proteins.

Abramow-Newerly M, Ming H, Chidiac P.

Cell Signal. 2006 Dec;18(12):2209-22. Epub 2006 May 23.

PMID:
16839744
32.

RGS17/RGSZ2 and the RZ/A family of regulators of G-protein signaling.

Nunn C, Mao H, Chidiac P, Albert PR.

Semin Cell Dev Biol. 2006 Jun;17(3):390-9. Epub 2006 Apr 7. Review.

PMID:
16765607
33.

RGS2 is upregulated by and attenuates the hypertrophic effect of alpha1-adrenergic activation in cultured ventricular myocytes.

Zou MX, Roy AA, Zhao Q, Kirshenbaum LA, Karmazyn M, Chidiac P.

Cell Signal. 2006 Oct;18(10):1655-63. Epub 2006 Mar 6.

PMID:
16517124
34.

RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins.

Abramow-Newerly M, Roy AA, Nunn C, Chidiac P.

Cell Signal. 2006 May;18(5):579-91. Epub 2005 Oct 13. Review.

PMID:
16226429
35.

RGS2 interacts with Gs and adenylyl cyclase in living cells.

Roy AA, Baragli A, Bernstein LS, Hepler JR, Hébert TE, Chidiac P.

Cell Signal. 2006 Mar;18(3):336-48. Epub 2005 Aug 10.

PMID:
16095880
36.

Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity.

Hepler JR, Cladman W, Ramineni S, Hollinger S, Chidiac P.

Biochemistry. 2005 Apr 12;44(14):5495-502.

PMID:
15807543
37.

Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes.

Gan XT, Rajapurohitam V, Haist JV, Chidiac P, Cook MA, Karmazyn M.

J Pharmacol Exp Ther. 2005 Jan;312(1):27-34. Epub 2004 Sep 27.

PMID:
15452191
38.

RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling.

Mao H, Zhao Q, Daigle M, Ghahremani MH, Chidiac P, Albert PR.

J Biol Chem. 2004 Jun 18;279(25):26314-22. Epub 2004 Apr 19.

39.

RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling.

Bernstein LS, Ramineni S, Hague C, Cladman W, Chidiac P, Levey AI, Hepler JR.

J Biol Chem. 2004 May 14;279(20):21248-56. Epub 2004 Feb 19.

40.
41.

Activity, regulation, and intracellular localization of RGS proteins.

Chidiac P, Roy AA.

Receptors Channels. 2003;9(3):135-47. Review.

PMID:
12775336
42.

Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line.

Chakraborty C, Barbin YP, Chakrabarti S, Chidiac P, Dixon SJ, Lala PK.

Mol Cell Endocrinol. 2003 Mar 28;201(1-2):63-73.

PMID:
12706295
43.

Characterization and comparison of RGS2 and RGS4 as GTPase-activating proteins for m2 muscarinic receptor-stimulated G(i).

Cladman W, Chidiac P.

Mol Pharmacol. 2002 Sep;62(3):654-9. Erratum in: Mol Pharmacol 2002 Oct;62(4):967.

PMID:
12181442
44.

Measuring RGS protein interactions with Gq alpha.

Chidiac P, Gadd ME, Hepler JR.

Methods Enzymol. 2002;344:686-702. No abstract available.

PMID:
11771420
45.

Considerations in the evaluation of inverse agonism and protean agonism at G protein-coupled receptors.

Chidiac P.

Methods Enzymol. 2002;343:3-16. No abstract available.

PMID:
11665576
46.

Calcitonin (CT) rapidly increases NA(+)/H(+) exchange and metabolic acid production: effects mediated selectively by the C1A CT receptor isoform.

Santhanagopal A, Chidiac P, Horne WC, Baron R, Dixon SJ.

Endocrinology. 2001 Oct;142(10):4401-13.

PMID:
11564704
47.

Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK.

McKinnon T, Chakraborty C, Gleeson LM, Chidiac P, Lala PK.

J Clin Endocrinol Metab. 2001 Aug;86(8):3665-74.

PMID:
11502794
48.

RGS3 is a GTPase-activating protein for g(ialpha) and g(qalpha) and a potent inhibitor of signaling by GTPase-deficient forms of g(qalpha) and g(11alpha).

Scheschonka A, Dessauer CW, Sinnarajah S, Chidiac P, Shi CS, Kehrl JH.

Mol Pharmacol. 2000 Oct;58(4):719-28.

PMID:
10999941
49.

Kinetic control of guanine nucleotide binding to soluble Galpha(q).

Chidiac P, Markin VS, Ross EM.

Biochem Pharmacol. 1999 Jul 1;58(1):39-48.

PMID:
10403517

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