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Items: 1 to 50 of 143

1.

Inhibition of DUSP6 sensitizes ovarian cancer cells to chemotherapeutic agents via regulation of ERK signaling response genes.

James NE, Beffa L, Oliver MT, Borgstadt AD, Emerson JB, Chichester CO, Yano N, Freiman RN, DiSilvestro PA, Ribeiro JR.

Oncotarget. 2019 May 21;10(36):3315-3327. eCollection 2019 May 21.

2.

Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins.

James NE, Cantillo E, Yano N, Chichester CO, DiSilvestro PA, Hovanesian V, Rao RSP, Kim KK, Moore RG, Ahsan N, Ribeiro JR.

Oncotarget. 2019 Apr 26;10(31):2959-2972. doi: 10.18632/oncotarget.26836. eCollection 2019 Apr 26.

3.

Human Epididymis Secretory Protein 4 (HE4) Compromises Cytotoxic Mononuclear Cells via Inducing Dual Specificity Phosphatase 6.

James NE, Oliver MT, Ribeiro JR, Cantillo E, Rowswell-Turner RB, Kim KK, Chichester CO 3rd, DiSilvestro PA, Moore RG, Singh RK, Yano N, Zhao TC.

Front Pharmacol. 2019 Mar 19;10:216. doi: 10.3389/fphar.2019.00216. eCollection 2019.

4.

HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells.

James NE, Cantillo E, Oliver MT, Rowswell-Turner RB, Ribeiro JR, Kim KK, Chichester CO 3rd, DiSilvestro PA, Moore RG, Singh RK, Yano N, Zhao TC.

Clin Exp Immunol. 2018 Sep;193(3):327-340. doi: 10.1111/cei.13153.

5.

Beyond the Biomarker: Understanding the Diverse Roles of Human Epididymis Protein 4 in the Pathogenesis of Epithelial Ovarian Cancer.

James NE, Chichester C, Ribeiro JR.

Front Oncol. 2018 Apr 24;8:124. doi: 10.3389/fonc.2018.00124. eCollection 2018. Review.

6.

Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns.

Digles D, Zdrazil B, Neefs JM, Van Vlijmen H, Herhaus C, Caracoti A, Brea J, Roibás B, Loza MI, Queralt-Rosinach N, Furlong LI, Gaulton A, Bartek L, Senger S, Chichester C, Engkvist O, Evelo CT, Franklin NI, Marren D, Ecker GF, Jacoby E.

Medchemcomm. 2016 Jun 1;7(6):1237-1244. Epub 2016 May 11.

7.

Target discovery from protein databases: challenges for curation.

Chichester C, Gaudet P.

Drug Discov Today Technol. 2015 Jul;14:11-6. doi: 10.1016/j.ddtec.2015.01.003. Epub 2015 May 30. Review.

PMID:
26194582
8.

The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells.

Wang Y, Han A, Chen E, Singh RK, Chichester CO, Moore RG, Singh AP, Vorsa N.

Int J Oncol. 2015 May;46(5):1924-34. doi: 10.3892/ijo.2015.2931. Epub 2015 Mar 17.

9.

The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.

Ratnam J, Zdrazil B, Digles D, Cuadrado-Rodriguez E, Neefs JM, Tipney H, Siebes R, Waagmeester A, Bradley G, Chau CH, Richter L, Brea J, Evelo CT, Jacoby E, Senger S, Loza MI, Ecker GF, Chichester C.

PLoS One. 2014 Dec 18;9(12):e115460. doi: 10.1371/journal.pone.0115460. eCollection 2014.

10.

Drug discovery FAQs: workflows for answering multidomain drug discovery questions.

Chichester C, Digles D, Siebes R, Loizou A, Groth P, Harland L.

Drug Discov Today. 2015 Apr;20(4):399-405. doi: 10.1016/j.drudis.2014.11.006. Epub 2014 Nov 20.

11.

Transporter assays and assay ontologies: useful tools for drug discovery.

Zdrazil B, Chichester C, Zander Balderud L, Engkvist O, Gaulton A, Overington JP.

Drug Discov Today Technol. 2014 Jun;12:e47-54. doi: 10.1016/j.ddtec.2014.03.005.

PMID:
25027375
12.

Inhibitory effects of polyphenol punicalagin on type-II collagen degradation in vitro and inflammation in vivo.

Jean-Gilles D, Li L, Vaidyanathan VG, King R, Cho B, Worthen DR, Chichester CO 3rd, Seeram NP.

Chem Biol Interact. 2013 Sep 25;205(2):90-9. doi: 10.1016/j.cbi.2013.06.018. Epub 2013 Jul 2.

PMID:
23830812
13.

Scientific competency questions as the basis for semantically enriched open pharmacological space development.

Azzaoui K, Jacoby E, Senger S, Rodríguez EC, Loza M, Zdrazil B, Pinto M, Williams AJ, de la Torre V, Mestres J, Pastor M, Taboureau O, Rarey M, Chichester C, Pettifer S, Blomberg N, Harland L, Williams-Jones B, Ecker GF.

Drug Discov Today. 2013 Sep;18(17-18):843-52. doi: 10.1016/j.drudis.2013.05.008. Epub 2013 May 20. Review.

14.

Annotating Human P-Glycoprotein Bioassay Data.

Zdrazil B, Pinto M, Vasanthanathan P, Williams AJ, Balderud LZ, Engkvist O, Chichester C, Hersey A, Overington JP, Ecker GF.

Mol Inform. 2012 Aug;31(8):599-609. Epub 2012 Aug 7.

15.

Preparation, structural analysis, and properties of tenoxicam cocrystals.

Patel JR, Carlton RA, Needham TE, Chichester CO, Vogt FG.

Int J Pharm. 2012 Oct 15;436(1-2):685-706. doi: 10.1016/j.ijpharm.2012.07.034. Epub 2012 Jul 25.

PMID:
22841852
16.

Open PHACTS: semantic interoperability for drug discovery.

Williams AJ, Harland L, Groth P, Pettifer S, Chichester C, Willighagen EL, Evelo CT, Blomberg N, Ecker G, Goble C, Mons B.

Drug Discov Today. 2012 Nov;17(21-22):1188-98. doi: 10.1016/j.drudis.2012.05.016. Epub 2012 Jun 7. Review.

17.

Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model.

Jean-Gilles D, Li L, Ma H, Yuan T, Chichester CO 3rd, Seeram NP.

J Agric Food Chem. 2012 Jun 13;60(23):5755-62. doi: 10.1021/jf203456w. Epub 2011 Dec 1.

18.

Professional technical standards in colleges and schools of pharmacy.

Berry TM, Chichester CO, Lundquist LM, Sanoski CA, Woodward DA, Worley MM, Early JL 2nd.

Am J Pharm Educ. 2011 Apr 11;75(3):50.

19.

The value of data.

Mons B, van Haagen H, Chichester C, Hoen PB, den Dunnen JT, van Ommen G, van Mulligen E, Singh B, Hooft R, Roos M, Hammond J, Kiesel B, Giardine B, Velterop J, Groth P, Schultes E.

Nat Genet. 2011 Mar 29;43(4):281-3. doi: 10.1038/ng0411-281.

PMID:
21445068
20.

Novel protein-protein interactions inferred from literature context.

van Haagen HH, 't Hoen PA, Botelho Bovo A, de Morrée A, van Mulligen EM, Chichester C, Kors JA, den Dunnen JT, van Ommen GJ, van der Maarel SM, Kern VM, Mons B, Schuemie MJ.

PLoS One. 2009 Nov 18;4(11):e7894. doi: 10.1371/journal.pone.0007894.

21.

In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts.

Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, Sharma S.

Placenta. 2008 Oct;29(10):871-8. doi: 10.1016/j.placenta.2008.07.009. Epub 2008 Sep 4.

22.

Shaping biological knowledge: applications in proteomics.

Lisacek F, Chichester C, Gonnet P, Jaillet O, Kappus S, Nikitin F, Roland P, Rossier G, Truong L, Appel R.

Comp Funct Genomics. 2004;5(2):190-5. doi: 10.1002/cfg.379.

23.

Calling on a million minds for community annotation in WikiProteins.

Mons B, Ashburner M, Chichester C, van Mulligen E, Weeber M, den Dunnen J, van Ommen GJ, Musen M, Cockerill M, Hermjakob H, Mons A, Packer A, Pacheco R, Lewis S, Berkeley A, Melton W, Barris N, Wales J, Meijssen G, Moeller E, Roes PJ, Borner K, Bairoch A.

Genome Biol. 2008;9(5):R89. doi: 10.1186/gb-2008-9-5-r89. Epub 2008 May 28.

24.

Evolution of non-cytotoxic uterine natural killer cells.

Kalkunte S, Chichester CO, Gotsch F, Sentman CL, Romero R, Sharma S.

Am J Reprod Immunol. 2008 May;59(5):425-32. doi: 10.1111/j.1600-0897.2008.00595.x. Review.

25.

Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo.

Andreev OA, Dupuy AD, Segala M, Sandugu S, Serra DA, Chichester CO, Engelman DM, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7893-8. Epub 2007 May 1.

26.

Assignment of protein function and discovery of novel nucleolar proteins based on automatic analysis of MEDLINE.

Schuemie M, Chichester C, Lisacek F, Coute Y, Roes PJ, Sanchez JC, Kors J, Mons B.

Proteomics. 2007 Mar;7(6):921-31.

PMID:
17370270
28.

Using argumentation to extract key sentences from biomedical abstracts.

Ruch P, Boyer C, Chichester C, Tbahriti I, Geissbühler A, Fabry P, Gobeill J, Pillet V, Rebholz-Schuhmann D, Lovis C, Veuthey AL.

Int J Med Inform. 2007 Feb-Mar;76(2-3):195-200. Epub 2006 Jul 11.

PMID:
16815739
29.

Review: Collagen markers in early arthritic diseases.

Elsaid KA, Chichester CO.

Clin Chim Acta. 2006 Mar;365(1-2):68-77. Epub 2005 Oct 28. Review.

PMID:
16257399
30.

Deciphering the human nucleolar proteome.

Couté Y, Burgess JA, Diaz JJ, Chichester C, Lisacek F, Greco A, Sanchez JC.

Mass Spectrom Rev. 2006 Mar-Apr;25(2):215-34. Review.

PMID:
16211575
31.

Using argumentation to retrieve articles with similar citations: an inquiry into improving related articles search in the MEDLINE digital library.

Tbahriti I, Chichester C, Lisacek F, Ruch P.

Int J Med Inform. 2006 Jun;75(6):488-95. Epub 2005 Sep 13.

PMID:
16165395
32.

Extracting key sentences with latent argumentative structuring.

Ruch P, Baud R, Chichester C, Geissbühler A, Lisacek F, Marty J, Rebholz-Schuhmann D, Tbahriti I, Veuthey AL.

Stud Health Technol Inform. 2005;116:835-40.

PMID:
16160362
33.
34.

Review of evidence: are endocrine-disrupting chemicals in the aquatic environment impacting fish populations?

Mills LJ, Chichester C.

Sci Total Environ. 2005 May 1;343(1-3):1-34. Review.

PMID:
15862833
35.

Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.

Ma Y, Sachdeva K, Liu J, Song X, Li Y, Yang D, Deng R, Chichester CO, Yan B.

Biochem Pharmacol. 2005 May 1;69(9):1363-71.

PMID:
15826607
36.

Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23.

Ma Y, Sachdeva K, Liu J, Ford M, Yang D, Khan IA, Chichester CO, Yan B.

Drug Metab Dispos. 2004 Nov;32(11):1317-24. Epub 2004 Jul 28.

PMID:
15282211
37.

Lubricating ability of aspirated synovial fluid from emergency department patients with knee joint synovitis.

Jay GD, Elsaid KA, Zack J, Robinson K, Trespalacios F, Cha CJ, Chichester CO.

J Rheumatol. 2004 Mar;31(3):557-64.

PMID:
14994405
39.

Consistency checks for characterizing protein forms.

Chichester C, Nikitin F, Ravarini JC, Lisacek F.

Comput Biol Chem. 2003 Feb;27(1):29-35.

PMID:
12798037
41.

Endotoxic shock alters the pharmacokinetics of lidocaine and monoethylglycinexylidide.

McKindley DS, Boulet J, Sachdeva K, Wang P, Chichester C.

Shock. 2002 Mar;17(3):199-204.

PMID:
11900338
42.

Heterogeneity of clara cell glutathione. A possible basis for differences in cellular responses to pulmonary cytotoxicants.

West JA, Chichester CH, Buckpitt AR, Tyler NK, Brennan P, Helton C, Plopper CG.

Am J Respir Cell Mol Biol. 2000 Jul;23(1):27-36.

PMID:
10873150
43.

Effect of endotoxin shock on the clearance of lidocaine and indocyanine green in the perfused rat liver.

McKindley DS, Chichester C, Raymond R.

Shock. 1999 Dec;12(6):468-72.

PMID:
10588516
44.

Articular collagen degradation in the Hulth-Telhag model of osteoarthritis.

Rogart JN, Barrach HJ, Chichester CO.

Osteoarthritis Cartilage. 1999 Nov;7(6):539-47.

45.

Type II collagen peptide release from rabbit articular cartilage.

Felice BR, Chichester CO, Barrach HJ.

Ann N Y Acad Sci. 1999 Jun 30;878:590-3. No abstract available.

PMID:
10415782
46.

Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow.

Mackay AM, Beck SC, Murphy JM, Barry FP, Chichester CO, Pittenger MF.

Tissue Eng. 1998 Winter;4(4):415-28.

PMID:
9916173
47.
48.

Interagency collaboration in services for people with co-occurring mental illness and substance use disorder.

Ridgely MS, Lambert D, Goodman A, Chichester CS, Ralph R.

Psychiatr Serv. 1998 Feb;49(2):236-8.

PMID:
9575013
49.

Induction of drug-metabolizing enzymes by dioxin.

Whitlock JP Jr, Chichester CH, Bedgood RM, Okino ST, Ko HP, Ma Q, Dong L, Li H, Clarke-Katzenberg R.

Drug Metab Rev. 1997 Nov;29(4):1107-27. Review. No abstract available.

PMID:
9421687
50.

[Markers of hepatic fibrogenesis in alcoholic patients].

de la Maza MP, Chichester C, Hirsch S, Petermann M, Iturriaga H, Bunout D.

Rev Med Chil. 1997 Jan;125(1):15-21. Spanish.

PMID:
9336064

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