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Items: 1 to 50 of 117

1.

In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent.

Baccarani M, Iacobucci I, Chiaretti S, Foà' R, Balasubramanian P, Paietta E, Foroni L, Jeromin S, Izzo B, Spinelli O, Varma N, Menif S, Terragna C, Seth T, Bidet A, Coriu D, Lunghi F, Mayer J, Scappini B, Langabeer S, Maier J, Burt E, Candoni A, Albano F, Luppi M, Zupan I, Lion T, Zadro R, di Raimondo F, Popak B, Rege-Cambrin G, Annunziata M, Ayala A, Salinas-Viedma V, Ines Prado A, Milner B, Galimberti S, Janssen J, Polli V, Comba L, Borsellino B, Annibali O, Crugnola M, Passamonti F.

Leukemia. 2019 Oct 8. doi: 10.1038/s41375-019-0591-9. [Epub ahead of print] No abstract available.

PMID:
31595038
2.

Efficacy of imatinib and chemotherapy in a pediatric patient with Philadelphia-like acute lymphoblastic leukemia with Ebf1-Pdgfrb fusion transcript.

Fazio F, Barberi W, Cazzaniga G, Fazio G, Messina M, Della Starza I, De Propris MS, Mancini F, Mohamed S, Del Giudice I, Chiaretti S, Moleti ML, Guarini A, Foà R, Testi AM.

Leuk Lymphoma. 2019 Sep 27:1-4. doi: 10.1080/10428194.2019.1668938. [Epub ahead of print] No abstract available.

PMID:
31558067
3.

Minimal Residual Disease in Acute Lymphoblastic Leukemia: Technical and Clinical Advances.

Della Starza I, Chiaretti S, De Propris MS, Elia L, Cavalli M, De Novi LA, Soscia R, Messina M, Vitale A, Guarini A, Foà R.

Front Oncol. 2019 Aug 7;9:726. doi: 10.3389/fonc.2019.00726. eCollection 2019. Review.

4.

Phase II trial with sequential clofarabine and cyclophosphamide for refractory and relapsed philadelphia-negative adult acute lymphoblastic leukemia. Results of the GIMEMA LAL 1610 protocol.

Bassan R, Fumagalli M, Chiaretti S, Audisio E, Cascavilla N, Paolini S, Delia M, Cerqui E, Micò C, Fabbiano F, Canichella M, Scattolin AM, Perfetti P, Paoloni F, Iodice M, Vitale A, Della Starza I, Fazi P, Vignetti M, Foà R.

Leuk Lymphoma. 2019 Jul 12:1-11. doi: 10.1080/10428194.2019.1639170. [Epub ahead of print]

PMID:
31298059
5.

Atypical Chronic Myeloid Leukemia in a Patient with Aplastic Anemia.

Santopietro M, Miano M, Palumbo G, Zhang K, Cardarelli L, Chiaretti S, Peragine N, Nanni M, Diverio D, Mancini F, Testi AM, Moleti ML, Foà R, Giona F.

Acta Haematol. 2019;142(3):185-186. doi: 10.1159/000497137. Epub 2019 May 21. No abstract available.

PMID:
31112981
6.

Digital droplet PCR and next-generation sequencing refine minimal residual disease monitoring in acute lymphoblastic leukemia.

Della Starza I, De Novi LA, Santoro A, Salemi D, Tam W, Cavalli M, Menale L, Soscia R, Apicella V, Ilari C, Vitale A, Testi AM, Inghirami G, Chiaretti S, Foà R, Guarini A.

Leuk Lymphoma. 2019 May 3:1-3. doi: 10.1080/10428194.2019.1607325. [Epub ahead of print] No abstract available.

PMID:
31050551
7.

BCR/ABL1-like acute lymphoblastic leukemia: How to diagnose and treat?

Chiaretti S, Messina M, Foà R.

Cancer. 2019 Jan 15;125(2):194-204. doi: 10.1002/cncr.31848. Epub 2018 Dec 18. Review.

PMID:
30561755
8.

Chemotherapy-free and reduced intensity approaches in elderly patients with B-lineage acute lymphoblastic leukemia.

Chiaretti S, Foà R.

Eur J Intern Med. 2018 Dec;58:22-27. doi: 10.1016/j.ejim.2018.05.028. Review.

PMID:
30527919
9.

Hematopoietic stem cell transplantation for adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first remission: a position statement of the European Working Group for Adult Acute Lymphoblastic Leukemia (EWALL) and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT).

Giebel S, Marks DI, Boissel N, Baron F, Chiaretti S, Ciceri F, Cornelissen JJ, Doubek M, Esteve J, Fielding A, Foa R, Gorin NC, Gökbuget N, Hallböök H, Hoelzer D, Paravichnikova E, Ribera JM, Savani B, Rijneveld AW, Schmid C, Wartiovaara-Kautto U, Mohty M, Nagler A, Dombret H.

Bone Marrow Transplant. 2019 Jun;54(6):798-809. doi: 10.1038/s41409-018-0373-4. Epub 2018 Nov 1. Review.

10.

New Approaches to the Management of Adult Acute Lymphoblastic Leukemia.

Bassan R, Bourquin JP, DeAngelo DJ, Chiaretti S.

J Clin Oncol. 2018 Sep 21:JCO2017773648. doi: 10.1200/JCO.2017.77.3648. [Epub ahead of print]

PMID:
30240326
11.

Prognostic implications of additional genomic lesions in adult Philadelphia chromosome-positive acute lymphoblastic leukemia.

Fedullo AL, Messina M, Elia L, Piciocchi A, Gianfelici V, Lauretti A, Soddu S, Puzzolo MC, Minotti C, Ferrara F, Martino B, Chiusolo P, Calafiore V, Paolini S, Vignetti M, Vitale A, Guarini A, Foà R, Chiaretti S.

Haematologica. 2019 Feb;104(2):312-318. doi: 10.3324/haematol.2018.196055. Epub 2018 Sep 6.

12.

IL7R overexpression in adult acute lymphoblastic leukemia is associated to JAK/STAT pathway mutations and identifies patients who could benefit from targeted therapies.

Gianfelici V, Messina M, Paoloni F, Peragine N, Lauretti A, Fedullo AL, Di Giacomo F, Vignetti M, Vitale A, Guarini A, Chiaretti S, Foà R.

Leuk Lymphoma. 2019 Mar;60(3):829-832. doi: 10.1080/10428194.2018.1499906. Epub 2018 Sep 6. No abstract available.

PMID:
30188230
13.

Autologous stem cell transplant in acute lymphoblastic leukemia: prognostic impact of pre-transplant minimal residual disease.

Capria S, Pepe S, Trisolini SM, Testi AM, Vitale A, De Propris MS, Della Starza I, Elia L, Guarini A, Chiaretti S, Foà R.

Leuk Lymphoma. 2019 Jan;60(1):274-276. doi: 10.1080/10428194.2018.1468895. Epub 2018 Jun 26. No abstract available.

PMID:
29944039
14.

Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications.

Chiaretti S, Messina M, Grammatico S, Piciocchi A, Fedullo AL, Di Giacomo F, Peragine N, Gianfelici V, Lauretti A, Bareja R, Martelli MP, Vignetti M, Apicella V, Vitale A, Li LS, Salek C, Elemento O, Inghirami G, Weinstock DM, Guarini A, Foà R.

Br J Haematol. 2018 Jun;181(5):642-652. doi: 10.1111/bjh.15251. Epub 2018 Apr 19.

15.

"Society of Hematologic Oncology (SOHO) State of the Art Updates and Next Questions"-Treatment of ALL.

Chiaretti S, Jabbour E, Hoelzer D.

Clin Lymphoma Myeloma Leuk. 2018 May;18(5):301-310. doi: 10.1016/j.clml.2018.03.014. Epub 2018 Apr 3. Review.

PMID:
29653823
16.

Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms.

Circosta P, Elia AR, Landra I, Machiorlatti R, Todaro M, Aliberti S, Brusa D, Deaglio S, Chiaretti S, Bruna R, Gottardi D, Massaia M, Giacomo FD, Guarini AR, Foà R, Kyriakides PW, Bareja R, Elemento O, Chichili GR, Monteleone E, Moore PA, Johnson S, Bonvini E, Cignetti A, Inghirami G.

Oncoimmunology. 2018 Feb 8;7(4):e1341032. doi: 10.1080/2162402X.2017.1341032. eCollection 2018.

17.

High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement.

La Starza R, Messina M, Gianfelici V, Pierini V, Matteucci C, Pierini T, Limongi MZ, Vitale A, Roti G, Chiaretti S, Foà R, Mecucci C.

Leukemia. 2018 Aug;32(8):1807-1810. doi: 10.1038/s41375-018-0031-2. Epub 2018 Feb 2. No abstract available.

PMID:
29479063
18.

Genetic landscape of ultra-stable chronic lymphocytic leukemia patients.

Raponi S, Del Giudice I, Marinelli M, Wang J, Cafforio L, Ilari C, Piciocchi A, Messina M, Bonina S, Tavolaro S, Bordyuh M, Mariglia P, Peragine N, Mauro FR, Chiaretti S, Molica S, Gentile M, Visentin A, Trentin L, Rigolin GM, Cuneo A, Diop F, Rossi D, Gaidano G, Guarini A, Rabadan R, Foà R.

Ann Oncol. 2018 Apr 1;29(4):966-972. doi: 10.1093/annonc/mdy021.

19.

Clinical significance of recurrent copy number aberrations in B-lineage acute lymphoblastic leukaemia without recurrent fusion genes across age cohorts.

Messina M, Chiaretti S, Fedullo AL, Piciocchi A, Puzzolo MC, Lauretti A, Gianfelici V, Apicella V, Fazi P, Te Kronnie G, Testi AM, Vitale A, Guarini A, Foà R.

Br J Haematol. 2017 Aug;178(4):583-587. doi: 10.1111/bjh.14721. Epub 2017 Apr 25.

PMID:
28439887
20.
21.

How has the management of Ph+ acute lymphoblastic leukemia (ALL) changed over the years.

Chiaretti S, Foà R.

Rinsho Ketsueki. 2016;57(10):2038-2048.

PMID:
27795512
22.

Liprin-α1 and ERC1 control cell edge dynamics by promoting focal adhesion turnover.

Astro V, Tonoli D, Chiaretti S, Badanai S, Sala K, Zerial M, de Curtis I.

Sci Rep. 2016 Sep 23;6:33653. doi: 10.1038/srep33653.

23.

A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study.

Chiaretti S, Vitale A, Vignetti M, Piciocchi A, Fazi P, Elia L, Falini B, Ronco F, Ferrara F, De Fabritiis P, Luppi M, La Nasa G, Tedeschi A, Califano C, Fanin R, Dore F, Mandelli F, Meloni G, Foà R.

Haematologica. 2016 Dec;101(12):1544-1552. Epub 2016 Aug 11.

24.

The genetics of nodal marginal zone lymphoma.

Spina V, Khiabanian H, Messina M, Monti S, Cascione L, Bruscaggin A, Spaccarotella E, Holmes AB, Arcaini L, Lucioni M, Tabbò F, Zairis S, Diop F, Cerri M, Chiaretti S, Marasca R, Ponzoni M, Deaglio S, Ramponi A, Tiacci E, Pasqualucci L, Paulli M, Falini B, Inghirami G, Bertoni F, Foà R, Rabadan R, Gaidano G, Rossi D.

Blood. 2016 Sep 8;128(10):1362-73. doi: 10.1182/blood-2016-02-696757. Epub 2016 Jun 22.

25.

Advances in the Genetics and Therapy of Acute Lymphoblastic Leukemia.

Chiaretti S, Gianfelici V, O'Brien SM, Mullighan CG.

Am Soc Clin Oncol Educ Book. 2016;35:e314-22. doi: 10.14694/EDBK_156628. Review.

26.

Comparative analysis between RQ-PCR and digital-droplet-PCR of immunoglobulin/T-cell receptor gene rearrangements to monitor minimal residual disease in acute lymphoblastic leukaemia.

Della Starza I, Nunes V, Cavalli M, De Novi LA, Ilari C, Apicella V, Vitale A, Testi AM, Del Giudice I, Chiaretti S, Foà R, Guarini A.

Br J Haematol. 2016 Aug;174(4):541-9. doi: 10.1111/bjh.14082. Epub 2016 May 12.

PMID:
27172403
27.

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications.

Gianfelici V, Chiaretti S, Demeyer S, Di Giacomo F, Messina M, La Starza R, Peragine N, Paoloni F, Geerdens E, Pierini V, Elia L, Mancini M, De Propris MS, Apicella V, Gaidano G, Testi AM, Vitale A, Vignetti M, Mecucci C, Guarini A, Cools J, Foà R.

Haematologica. 2016 Aug;101(8):941-50. doi: 10.3324/haematol.2015.139410. Epub 2016 May 5.

28.

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia.

La Starza R, Barba G, Demeyer S, Pierini V, Di Giacomo D, Gianfelici V, Schwab C, Matteucci C, Vicente C, Cools J, Messina M, Crescenzi B, Chiaretti S, Foà R, Basso G, Harrison CJ, Mecucci C.

Haematologica. 2016 Aug;101(8):951-8. doi: 10.3324/haematol.2016.143875. Epub 2016 May 5.

29.

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.

Messina M, Chiaretti S, Wang J, Fedullo AL, Peragine N, Gianfelici V, Piciocchi A, Brugnoletti F, Di Giacomo F, Pauselli S, Holmes AB, Puzzolo MC, Ceglie G, Apicella V, Mancini M, Te Kronnie G, Testi AM, Vitale A, Vignetti M, Guarini A, Rabadan R, Foà R.

Oncotarget. 2016 Mar 22;7(12):13886-901. doi: 10.18632/oncotarget.7356.

30.

Role of Liprins in the Regulation of Tumor Cell Motility and Invasion.

Chiaretti S, de Curtis I.

Curr Cancer Drug Targets. 2016;16(3):238-48. Review.

PMID:
26882029
31.

Clinical impact of low-burden BCR-ABL1 mutations detectable by amplicon deep sequencing in Philadelphia-positive acute lymphoblastic leukemia patients.

Soverini S, De Benedittis C, Papayannidis C, Polakova KM, Venturi C, Russo D, Bresciani P, Iurlo A, Mancini M, Vitale A, Chiaretti S, Foà R, Abruzzese E, Sorà F, Kohlmann A, Haferlach T, Baccarani M, Cavo M, Martinelli G.

Leukemia. 2016 Jul;30(7):1615-9. doi: 10.1038/leu.2016.17. Epub 2016 Feb 12. No abstract available.

PMID:
26867670
32.

CRLF2 overexpression identifies an unfavourable subgroup of adult B-cell precursor acute lymphoblastic leukemia lacking recurrent genetic abnormalities.

Chiaretti S, Brugnoletti F, Messina M, Paoloni F, Fedullo AL, Piciocchi A, Elia L, Vitale A, Mauro E, Ferrara F, De Fabritiis P, Luppi M, Ronco F, De Propris MS, Raponi S, Kronnie GT, Vignetti M, Guarini A, Foà R.

Leuk Res. 2016 Feb;41:36-42. doi: 10.1016/j.leukres.2015.11.018. Epub 2015 Dec 23.

PMID:
26754556
33.

Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.

Chiaretti S, Astro V, Chiricozzi E, de Curtis I.

Biol Cell. 2016 Mar;108(3):65-75. doi: 10.1111/boc.201500063. Epub 2016 Feb 5.

PMID:
26663347
34.

Management of adult Ph-positive acute lymphoblastic leukemia.

Chiaretti S, Foà R.

Hematology Am Soc Hematol Educ Program. 2015;2015:406-13. doi: 10.1182/asheducation-2015.1.406. Review.

PMID:
26637750
35.

Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments.

Del Giudice I, Marinelli M, Wang J, Bonina S, Messina M, Chiaretti S, Ilari C, Cafforio L, Raponi S, Mauro FR, Di Maio V, De Propris MS, Nanni M, Ciardullo C, Rossi D, Gaidano G, Guarini A, Rabadan R, Foà R.

Br J Haematol. 2016 Feb;172(3):371-383. doi: 10.1111/bjh.13859. Epub 2015 Nov 24.

36.

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.

Pennucci R, Talpo F, Astro V, Montinaro V, Morè L, Cursi M, Castoldi V, Chiaretti S, Bianchi V, Marenna S, Cambiaghi M, Tonoli D, Leocani L, Biella G, D'Adamo P, de Curtis I.

Cereb Cortex. 2016 Feb;26(2):873-890. doi: 10.1093/cercor/bhv274. Epub 2015 Nov 17.

37.

A case of lineage switch from B-cell acute lymphoblastic leukaemia to acute myeloid leukaemia. Role of subclonal/clonal gene mutations.

Della Starza I, Ceglie G, Nunes V, Gianfelici V, Marinelli M, Fuligni F, De Novi LA, De Propris MS, Vitale A, Chiaretti S, Guarini A, Foà R.

Br J Haematol. 2016 Aug;174(4):648-51. doi: 10.1111/bjh.13800. Epub 2015 Oct 12. No abstract available.

PMID:
26456857
38.

The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPα.

Vargas Romero P, Cialfi S, Palermo R, De Blasio C, Checquolo S, Bellavia D, Chiaretti S, Foà R, Amadori A, Gulino A, Zardo G, Talora C, Screpanti I.

Leukemia. 2015 Dec;29(12):2442-5. doi: 10.1038/leu.2015.117. Epub 2015 May 18. No abstract available.

39.

CD45 antigen negativity in T-lineage ALL correlates with PTPRC mutation and sensitivity to a selective JAK inhibitor.

Raponi S, Gianfelici V, Chiaretti S, Peragine N, Brugnoletti F, De Propris MS, Marinelli M, Hulselmans G, Aerts S, Geerdens E, Cools J, Foà R, Guarini A.

Br J Haematol. 2015 Dec;171(5):884-7. doi: 10.1111/bjh.13448. Epub 2015 Apr 8. No abstract available.

PMID:
25854815
40.

Impairment of the Pin1/E2F1 axis in the anti-proliferative effect of bortezomib in hepatocellular carcinoma cells.

Farra R, Dapas B, Baiz D, Tonon F, Chiaretti S, Del Sal G, Rustighi A, Elvassore N, Pozzato G, Grassi M, Grassi G.

Biochimie. 2015 May;112:85-95. doi: 10.1016/j.biochi.2015.02.015. Epub 2015 Mar 3.

PMID:
25742740
41.

Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212.

Tavolaro S, Colombo T, Chiaretti S, Peragine N, Fulci V, Ricciardi MR, Messina M, Bonina S, Brugnoletti F, Marinelli M, Di Maio V, Mauro FR, Del Giudice I, Macino G, Foà R, Guarini A.

Genes Chromosomes Cancer. 2015 Apr;54(4):222-34. doi: 10.1002/gcc.22236. Epub 2015 Feb 2.

PMID:
25645730
42.

Diagnosis and subclassification of acute lymphoblastic leukemia.

Chiaretti S, Zini G, Bassan R.

Mediterr J Hematol Infect Dis. 2014 Nov 1;6(1):e2014073. doi: 10.4084/MJHID.2014.073. eCollection 2014. Review.

43.

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations.

La Starza R, Borga C, Barba G, Pierini V, Schwab C, Matteucci C, Lema Fernandez AG, Leszl A, Cazzaniga G, Chiaretti S, Basso G, Harrison CJ, Te Kronnie G, Mecucci C.

Blood. 2014 Dec 4;124(24):3577-82. doi: 10.1182/blood-2014-06-578856. Epub 2014 Sep 30.

PMID:
25270907
44.

A case of late isolated ovarian relapse of acute lymphoblastic leukemia after an allogeneic stem cell transplant.

Nunes V, Della Starza I, Canichella M, Cavalli M, De Propris MS, Messina M, Capria S, Torelli GF, Vitale A, Guarini A, Chiaretti S, Foà R.

Leuk Lymphoma. 2015 May;56(5):1517-20. doi: 10.3109/10428194.2014.956317. Epub 2014 Nov 5. No abstract available.

PMID:
25204371
45.

The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells.

Zampieri M, Ciccarone F, Palermo R, Cialfi S, Passananti C, Chiaretti S, Nocchia D, Talora C, Screpanti I, Caiafa P.

Biochim Biophys Acta. 2014 Sep;1839(9):813-25. doi: 10.1016/j.bbagrm.2014.06.017. Epub 2014 Jun 28.

46.

Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.

Astro V, Chiaretti S, Magistrati E, Fivaz M, de Curtis I.

J Cell Sci. 2014 Sep 1;127(Pt 17):3862-76. doi: 10.1242/jcs.155663. Epub 2014 Jun 30.

47.

Genomic characterization of acute leukemias.

Chiaretti S, Gianfelici V, Ceglie G, Foà R.

Med Princ Pract. 2014;23(6):487-506. doi: 10.1159/000362793. Epub 2014 Jun 20. Review.

48.

NOTCH1, SF3B1, BIRC3 and TP53 mutations in patients with chronic lymphocytic leukemia undergoing first-line treatment: correlation with biological parameters and response to treatment.

Chiaretti S, Marinelli M, Del Giudice I, Bonina S, Piciocchi A, Messina M, Vignetti M, Rossi D, Di Maio V, Mauro FR, Guarini A, Gaidano G, Foà R.

Leuk Lymphoma. 2014 Dec;55(12):2785-92. doi: 10.3109/10428194.2014.898760.

PMID:
24597984
49.

DDX3X-MLLT10 fusion in adults with NOTCH1 positive T-cell acute lymphoblastic leukemia.

Brandimarte L, La Starza R, Gianfelici V, Barba G, Pierini V, Di Giacomo D, Cools J, Elia L, Vitale A, Luciano L, Bardi A, Chiaretti S, Matteucci C, Specchia G, Mecucci C.

Haematologica. 2014 May;99(5):64-6. doi: 10.3324/haematol.2013.101725. Epub 2014 Feb 28. No abstract available.

50.

Bortezomib effect on E2F and cyclin family members in human hepatocellular carcinoma cell lines.

Baiz D, Dapas B, Farra R, Scaggiante B, Pozzato G, Zanconati F, Fiotti N, Consoloni L, Chiaretti S, Grassi G.

World J Gastroenterol. 2014 Jan 21;20(3):795-803. doi: 10.3748/wjg.v20.i3.795.

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