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Items: 38


Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses.

Adams RA, Fernandes-Cerqueira C, Notarnicola A, Mertsching E, Xu Z, Lo WS, Ogilvie K, Chiang KP, Ampudia J, Rosengren S, Cubitt A, King DJ, Mendlein JD, Yang XL, Nangle LA, Lundberg IE, Jakobsson PJ, Schimmel P.

Cell Mol Immunol. 2019 Dec 4. doi: 10.1038/s41423-019-0331-0. [Epub ahead of print]


The impact of giant jellyfish Nemopilema nomurai blooms on plankton communities in a temperate marginal sea.

Xiao W, Zeng Y, Liu X, Huang X, Chiang KP, Mi T, Zhang F, Li C, Wei H, Yao Q, Huang B.

Mar Pollut Bull. 2019 Dec;149:110507. doi: 10.1016/j.marpolbul.2019.110507. Epub 2019 Aug 12.


Abiotic and Biotic Factors Affecting the Ingestion Rates of Mixotrophic Nanoflagellates (Haptophyta).

Chan YF, Chiang KP, Ku Y, Gong GC.

Microb Ecol. 2019 Apr;77(3):607-615. doi: 10.1007/s00248-018-1249-2. Epub 2018 Sep 5.


Predator and prey biodiversity relationship and its consequences on marine ecosystem functioning-interplay between nanoflagellates and bacterioplankton.

Yang JW, Wu W, Chung CC, Chiang KP, Gong GC, Hsieh CH.

ISME J. 2018 Jun;12(6):1532-1542. doi: 10.1038/s41396-018-0111-3. Epub 2018 Apr 27.


The dynamics of a dominant dinoflagellate, Noctiluca scintillans, in the subtropical coastal waters of the Matsu archipelago.

Tsai SF, Wu LY, Chou WC, Chiang KP.

Mar Pollut Bull. 2018 Feb;127:553-558. doi: 10.1016/j.marpolbul.2017.12.041. Epub 2017 Dec 22.


Community Composition of Photosynthetic Picoeukaryotes in a Subtropical Coastal Ecosystem, with Particular Emphasis on Micromonas.

Lin YC, Chung CC, Chen LY, Gong GC, Huang CY, Chiang KP.

J Eukaryot Microbiol. 2017 May;64(3):349-359. doi: 10.1111/jeu.12370. Epub 2016 Oct 13.


Physical-Biological Coupling in the Western South China Sea: The Response of Phytoplankton Community to a Mesoscale Cyclonic Eddy.

Wang L, Huang B, Chiang KP, Liu X, Chen B, Xie Y, Xu Y, Hu J, Dai M.

PLoS One. 2016 Apr 18;11(4):e0153735. doi: 10.1371/journal.pone.0153735. eCollection 2016.


Strains of the Morphospecies Ploeotia costata (Euglenozoa) Isolated from the Western North Pacific (Taiwan) Reveal Substantial Genetic Differences.

Chan YF, Chiang KP, Chang J, Moestrup Ø, Chung CC.

J Eukaryot Microbiol. 2015 May-Jun;62(3):318-26. doi: 10.1111/jeu.12183. Epub 2014 Nov 19.


Human tRNA synthetase catalytic nulls with diverse functions.

Lo WS, Gardiner E, Xu Z, Lau CF, Wang F, Zhou JJ, Mendlein JD, Nangle LA, Chiang KP, Yang XL, Au KF, Wong WH, Guo M, Zhang M, Schimmel P.

Science. 2014 Jul 18;345(6194):328-32. doi: 10.1126/science.1252943.


Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.

Zhou JJ, Wang F, Xu Z, Lo WS, Lau CF, Chiang KP, Nangle LA, Ashlock MA, Mendlein JD, Yang XL, Zhang M, Schimmel P.

J Biol Chem. 2014 Jul 11;289(28):19269-75. doi: 10.1074/jbc.C114.571026. Epub 2014 Jun 4.


Multimetallic Cooperativity in Activation of Dinitrogen at Iron-Potassium Sites.

Chiang KP, Bellows SM, Brennessel WW, Holland PL.

Chem Sci. 2014 Jan 1;5(1). doi: 10.1039/C3SC52487F.


Sensitivity of X-ray core spectroscopy to changes in metal ligation: a systematic study of low-coordinate, high-spin ferrous complexes.

Chandrasekaran P, Chiang KP, Nordlund D, Bergmann U, Holland PL, DeBeer S.

Inorg Chem. 2013 Jun 3;52(11):6286-98. doi: 10.1021/ic3021723. Epub 2013 May 10.


Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing.

Xu Z, Wei Z, Zhou JJ, Ye F, Lo WS, Wang F, Lau CF, Wu J, Nangle LA, Chiang KP, Yang XL, Zhang M, Schimmel P.

Structure. 2012 Sep 5;20(9):1470-7. doi: 10.1016/j.str.2012.08.001.


Characterization of the Fe-H bond in a three-coordinate terminal hydride complex of iron(I).

Chiang KP, Scarborough CC, Horitani M, Lees NS, Ding K, Dugan TR, Brennessel WW, Bill E, Hoffman BM, Holland PL.

Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3658-62. doi: 10.1002/anie.201109204. Epub 2012 Feb 28. No abstract available.


Distribution patterns and phylogeny of marine stramenopiles in the north pacific ocean.

Lin YC, Campbell T, Chung CC, Gong GC, Chiang KP, Worden AZ.

Appl Environ Microbiol. 2012 May;78(9):3387-99. doi: 10.1128/AEM.06952-11. Epub 2012 Feb 17.


Identification of a single light atom within a multinuclear metal cluster using valence-to-core X-ray emission spectroscopy.

Delgado-Jaime MU, Dible BR, Chiang KP, Brennessel WW, Bergmann U, Holland PL, DeBeer S.

Inorg Chem. 2011 Nov 7;50(21):10709-17. doi: 10.1021/ic201173j. Epub 2011 Sep 28.


Effects of Asian dust storms on synechococcus populations in the subtropical Kuroshio Current.

Chung CC, Chang J, Gong GC, Hsu SC, Chiang KP, Liao CW.

Mar Biotechnol (NY). 2011 Aug;13(4):751-63. doi: 10.1007/s10126-010-9336-5. Epub 2010 Dec 14.


Spirotontonia taiwanica n. sp. (Ciliophora: Oligotrichida) from the coastal waters of northeastern Taiwan: morphology and nuclear small subunit rDNA Sequence.

Tsai SF, Chen JY, Chiang KP.

J Eukaryot Microbiol. 2010 Sep-Oct;57(5):429-34. doi: 10.1111/j.1550-7408.2010.00494.x. Epub 2010 Jul 20.


Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.

Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D.

J Lipid Res. 2010 Oct;51(10):2896-908. doi: 10.1194/jlr.M004259. Epub 2010 Jul 12.


Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.

McGinty RK, Köhn M, Chatterjee C, Chiang KP, Pratt MR, Muir TW.

ACS Chem Biol. 2009 Nov 20;4(11):958-68. doi: 10.1021/cb9002255.


Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe.

Pratt MR, Sekedat MD, Chiang KP, Muir TW.

Chem Biol. 2009 Sep 25;16(9):1001-12. doi: 10.1016/j.chembiol.2009.07.011.


Pigmented nanoflagellates grazing on Synechococcus: seasonal variations and effect of flagellate size in the coastal ecosystem of subtropical Western Pacific.

Chan YF, Tsai AY, Chiang KP, Hsieh CH.

Microb Ecol. 2009 Oct;58(3):548-57. doi: 10.1007/s00248-009-9569-x. Epub 2009 Aug 5.


A semisynthetic strategy to generate phosphorylated and acetylated histone H2B.

Chiang KP, Jensen MS, McGinty RK, Muir TW.

Chembiochem. 2009 Sep 4;10(13):2182-7. doi: 10.1002/cbic.200900238. No abstract available.


Ligand dependence of binding to three-coordinate Fe(II) complexes.

Chiang KP, Barrett PM, Ding F, Smith JM, Kingsley S, Brennessel WW, Clark MM, Lachicotte RJ, Holland PL.

Inorg Chem. 2009 Jun 15;48(12):5106-16. doi: 10.1021/ic802440h.


Synthesis of a bulky bis(imino)pyridine compound: a methodology for systematic variation of steric bulk and energetic implications for metalation.

Steves JE, Kennedy MD, Chiang KP, Kassel WS, Dougherty WG, Dudley TJ, Zubris DL.

Dalton Trans. 2009 Feb 21;(7):1214-22. doi: 10.1039/b815987d. Epub 2008 Dec 18.


Parastrombidinopsis minima n. sp. (Ciliophora: Oligotrichia) from the coastal waters of northeastern Taiwan: morphology and small subunit ribosomal DNA sequence.

Tsai SF, Xu D, Chung CC, Chiang KP.

J Eukaryot Microbiol. 2008 Nov-Dec;55(6):567-73. doi: 10.1111/j.1550-7408.2008.00364.x.


Systems- and molecular-level elucidation of signaling processes through chemistry.

Chiang KP, Muir TW.

Sci Signal. 2008 Oct 21;1(42):pe45. doi: 10.1126/scisignal.142pe45. Review.


An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.

Chiang KP, Niessen S, Saghatelian A, Cravatt BF.

Chem Biol. 2006 Oct;13(10):1041-50.


Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions.

Nomura DK, Durkin KA, Chiang KP, Quistad GB, Cravatt BF, Casida JE.

Chem Res Toxicol. 2006 Sep;19(9):1142-50.


Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: kinetic stabilization of the native state.

Petrassi HM, Johnson SM, Purkey HE, Chiang KP, Walkup T, Jiang X, Powers ET, Kelly JW.

J Am Chem Soc. 2005 May 11;127(18):6662-71.


A brain detoxifying enzyme for organophosphorus nerve poisons.

Nomura DK, Leung D, Chiang KP, Quistad GB, Cravatt BF, Casida JE.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6195-200. Epub 2005 Apr 19.


Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation.

Johnson SM, Petrassi HM, Palaninathan SK, Mohamedmohaideen NN, Purkey HE, Nichols C, Chiang KP, Walkup T, Sacchettini JC, Sharpless KB, Kelly JW.

J Med Chem. 2005 Mar 10;48(5):1576-87.


Design, synthesis, and evaluation of oxazole transthyretin amyloidogenesis inhibitors.

Razavi H, Powers ET, Purkey HE, Adamski-Werner SL, Chiang KP, Dendle MT, Kelly JW.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):1075-8.


Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action.

Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW.

Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. No abstract available.


Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors.

Oza VB, Smith C, Raman P, Koepf EK, Lashuel HA, Petrassi HM, Chiang KP, Powers ET, Sachettinni J, Kelly JW.

J Med Chem. 2002 Jan 17;45(2):321-32.


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