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Items: 1 to 50 of 67

1.

Narrow-band imaging for scar classification: from conception to multicenter validation.

Cheng Tao Pu LZ, Chiam KH, Yamamura T, Nakamura M, Berzin TM, Mir FF, Hourneaux de Moura EG, Madruga Neto AC, Ching Koay DS, Loong CK, Ovenden A, Edwards S, Burt AD, Hirooka Y, Fujishiro M, Singh R.

Gastrointest Endosc. 2019 Sep 5. pii: S0016-5107(19)32206-0. doi: 10.1016/j.gie.2019.08.036. [Epub ahead of print]

PMID:
31494134
2.

Regulation of flagellar motor switching by c-di-GMP phosphodiesterases in Pseudomonas aeruginosa.

Xin L, Zeng Y, Sheng S, Chea RA, Liu Q, Li HY, Yang L, Xu L, Chiam KH, Liang ZX.

J Biol Chem. 2019 Sep 13;294(37):13789-13799. doi: 10.1074/jbc.RA119.009009. Epub 2019 Jul 26.

PMID:
31350333
3.

Superresolution microscopy reveals distinct localisation of full length IRSp53 and its I-BAR domain protein within filopodia.

Sudhaharan T, Hariharan S, Lim JSY, Liu JZ, Koon YL, Wright GD, Chiam KH, Ahmed S.

Sci Rep. 2019 Feb 21;9(1):2524. doi: 10.1038/s41598-019-38851-w.

4.

ASO Author Reflections: Predicting the Response of Esophageal Adenocarcinoma to Chemoradiotherapy Before Surgery Using MicroRNA Biomarkers Offers Hope to Improve Outcomes by Tailoring Treatment to Predicted Responses.

Mayne GC, Watson DI, Chiam K, Hussey DJ.

Ann Surg Oncol. 2018 Dec;25(Suppl 3):755-756. doi: 10.1245/s10434-018-6958-8. Epub 2018 Oct 25. No abstract available.

PMID:
30362067
5.

Enrichment and Identification of Neural Stem Cells in Neurospheres Using Rigidity-Tunable Gels.

Chew S, Zeng Y, Khoo D, Hong Yu MY, Ahmed S, Chiam KH.

Tissue Eng Part A. 2019 Mar;25(5-6):427-436. doi: 10.1089/ten.TEA.2018.0221. Epub 2019 Feb 25.

PMID:
30319044
6.

An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy.

Zhang AY, Chiam K, Haupt Y, Fox S, Birch S, Tilley W, Butler LM, Knudsen K, Comstock C, Rasiah K, Grogan J, Mahon KL, Bianco-Miotto T, Ricciardelli C, Böhm M, Henshall S, Delprado W, Stricker P, Horvath LG, Kench JG.

Int J Cancer. 2019 Mar 1;144(5):1151-1159. doi: 10.1002/ijc.31906. Epub 2018 Dec 4.

PMID:
30288742
7.

Anisotropic traction stresses and focal adhesion polarization mediates topography-induced cell elongation.

Yip AK, Nguyen AT, Rizwan M, Wong ST, Chiam KH, Yim EKF.

Biomaterials. 2018 Oct;181:103-112. doi: 10.1016/j.biomaterials.2018.07.057. Epub 2018 Jul 30.

PMID:
30081301
8.

Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing.

Chiam K, Mayne GC, Watson DI, Woodman RJ, Bright TF, Michael MZ, Karapetis CS, Irvine T, Phillips WA, Hummel R, Wang T, Pimlott LK, Marri S, Astill DS, Ruszkiewicz AR, Thompson SK, Hussey DJ.

Ann Surg Oncol. 2018 Sep;25(9):2731-2738. doi: 10.1245/s10434-018-6626-z. Epub 2018 Jul 9.

PMID:
29987600
10.

Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature.

Zeng Y, Wong ST, Teo SK, Leong KW, Chiam KH, Yim EKF.

Sci Rep. 2018 Apr 24;8(1):6444. doi: 10.1038/s41598-018-24123-6.

11.

Cell-Cell Adhesion and Cortical Actin Bending Govern Cell Elongation on Negatively Curved Substrates.

Yip AK, Huang P, Chiam KH.

Biophys J. 2018 Apr 10;114(7):1707-1717. doi: 10.1016/j.bpj.2018.02.027.

12.

A computational model for how cells choose temporal or spatial sensing during chemotaxis.

Tan RZ, Chiam KH.

PLoS Comput Biol. 2018 Mar 5;14(3):e1005966. doi: 10.1371/journal.pcbi.1005966. eCollection 2018 Mar.

13.

Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein.

Yan XF, Xin L, Yen JT, Zeng Y, Jin S, Cheang QW, Fong RACY, Chiam KH, Liang ZX, Gao YG.

J Biol Chem. 2018 Jan 5;293(1):100-111. doi: 10.1074/jbc.M117.815704. Epub 2017 Nov 16.

14.

The role of apical contractility in determining cell morphology in multilayered epithelial sheets and tubes.

Tan RZ, Lai T, Chiam KH.

Phys Biol. 2017 Jul 19;14(4):046003. doi: 10.1088/1478-3975/aa7afc.

PMID:
28639563
15.

Comparison of cellular oscillations driven by noise or deterministic mechanisms under cell-size scaling.

He C, Chiam KH, Chew LY.

Phys Rev E. 2016 Oct;94(4-1):042425. Epub 2016 Oct 28.

PMID:
27841613
16.

A cyclic di-GMP-binding adaptor protein interacts with a chemotaxis methyltransferase to control flagellar motor switching.

Xu L, Xin L, Zeng Y, Yam JK, Ding Y, Venkataramani P, Cheang QW, Yang X, Tang X, Zhang LH, Chiam KH, Yang L, Liang ZX.

Sci Signal. 2016 Oct 18;9(450):ra102.

PMID:
27811183
17.

MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility.

Hirata H, Ku WC, Yip AK, Ursekar CP, Kawauchi K, Roy A, Guo AK, Vedula SR, Harada I, Chiam KH, Ishihama Y, Lim CT, Sawada Y, Sokabe M.

J Cell Sci. 2016 Oct 1;129(19):3574-3582. Epub 2016 Aug 15.

18.

Ciliary metachronal wave propagation on the compliant surface of Paramecium cells.

Narematsu N, Quek R, Chiam KH, Iwadate Y.

Cytoskeleton (Hoboken). 2015 Dec;72(12):633-46. doi: 10.1002/cm.21266. Epub 2015 Dec 22.

PMID:
26616106
19.

Cellular Subcompartments through Cytoplasmic Streaming.

Pieuchot L, Lai J, Loh RA, Leong FY, Chiam KH, Stajich J, Jedd G.

Dev Cell. 2015 Aug 24;34(4):410-20. doi: 10.1016/j.devcel.2015.07.017.

20.
21.

Circulating Serum Exosomal miRNAs As Potential Biomarkers for Esophageal Adenocarcinoma.

Chiam K, Wang T, Watson DI, Mayne GC, Irvine TS, Bright T, Smith L, White IA, Bowen JM, Keefe D, Thompson SK, Jones ME, Hussey DJ.

J Gastrointest Surg. 2015 Jul;19(7):1208-15. doi: 10.1007/s11605-015-2829-9. Epub 2015 May 6.

PMID:
25943911
22.

Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer.

Mahon KL, Lin HM, Castillo L, Lee BY, Lee-Ng M, Chatfield MD, Chiam K, Breit SN, Brown DA, Molloy MP, Marx GM, Pavlakis N, Boyer MJ, Stockler MR, Daly RJ, Henshall SM, Horvath LG.

Br J Cancer. 2015 Apr 14;112(8):1340-8. doi: 10.1038/bjc.2015.74. Epub 2015 Mar 31.

23.

Computational modeling reveals that a combination of chemotaxis and differential adhesion leads to robust cell sorting during tissue patterning.

Tan RZ, Chiam KH.

PLoS One. 2014 Oct 10;9(10):e109286. doi: 10.1371/journal.pone.0109286. eCollection 2014.

24.

INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival.

Rynkiewicz NK, Fedele CG, Chiam K, Gupta R, Kench JG, Ooms LM, McLean CA, Giles GG, Horvath LG, Mitchell CA.

Prostate. 2015 Jan;75(1):92-102. doi: 10.1002/pros.22895. Epub 2014 Oct 4.

PMID:
25284366
25.

Expression of E6AP and PML predicts for prostate cancer progression and cancer-specific death.

Birch SE, Kench JG, Takano E, Chan P, Chan AL, Chiam K, Veillard AS, Stricker P, Haupt S, Haupt Y, Horvath L, Fox SB.

Ann Oncol. 2014 Dec;25(12):2392-7. doi: 10.1093/annonc/mdu454. Epub 2014 Sep 17.

PMID:
25231954
26.

Actin flow and talin dynamics govern rigidity sensing in actin-integrin linkage through talin extension.

Hirata H, Chiam KH, Lim CT, Sokabe M.

J R Soc Interface. 2014 Oct 6;11(99). pii: 20140734. doi: 10.1098/rsif.2014.0734.

27.

Extending neurites sense the depth of the underlying topography during neuronal differentiation and contact guidance.

Chua JS, Chng CP, Moe AA, Tann JY, Goh EL, Chiam KH, Yim EK.

Biomaterials. 2014 Sep;35(27):7750-61. doi: 10.1016/j.biomaterials.2014.06.008. Epub 2014 Jun 19.

PMID:
24954734
28.

Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas.

Al Robaian M, Chiam KY, Blatchford DR, Dufès C.

Nanomedicine (Lond). 2014 Apr;9(4):421-34. doi: 10.2217/NNM.13.25.

29.

A forgotten clinical sign making a comeback.

Chiam KH, A Hing CT, Low LL.

Med J Malaysia. 2014 Feb;69(1):40-1.

30.

Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer.

Lin HM, Castillo L, Mahon KL, Chiam K, Lee BY, Nguyen Q, Boyer MJ, Stockler MR, Pavlakis N, Marx G, Mallesara G, Gurney H, Clark SJ, Swarbrick A, Daly RJ, Horvath LG.

Br J Cancer. 2014 May 13;110(10):2462-71. doi: 10.1038/bjc.2014.181. Epub 2014 Apr 8.

31.

Computational modeling reveals optimal strategy for kinase transport by microtubules to nerve terminals.

Koon YL, Koh CG, Chiam KH.

PLoS One. 2014 Apr 1;9(4):e92437. doi: 10.1371/journal.pone.0092437. eCollection 2014.

32.

p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.

Yamauchi S, Hou YY, Guo AK, Hirata H, Nakajima W, Yip AK, Yu CH, Harada I, Chiam KH, Sawada Y, Tanaka N, Kawauchi K.

J Cell Biol. 2014 Mar 31;204(7):1191-207. doi: 10.1083/jcb.201309107. Epub 2014 Mar 24.

33.

Loss of p53 enhances NF-κB-dependent lamellipodia formation.

Guo AK, Hou YY, Hirata H, Yamauchi S, Yip AK, Chiam KH, Tanaka N, Sawada Y, Kawauchi K.

J Cell Physiol. 2014 Jun;229(6):696-704. Erratum in: J Cell Physiol. 2014 Oct;229(10):1569.

PMID:
24647813
34.

Design and construction of an equibiaxial cell stretching system that is improved for biochemical analysis.

Ursekar CP, Teo SK, Hirata H, Harada I, Chiam KH, Sawada Y.

PLoS One. 2014 Mar 13;9(3):e90665. doi: 10.1371/journal.pone.0090665. eCollection 2014.

35.

POPX2 phosphatase regulates the KIF3 kinesin motor complex.

Phang HQ, Hoon JL, Lai SK, Zeng Y, Chiam KH, Li HY, Koh CG.

J Cell Sci. 2014 Feb 15;127(Pt 4):727-39. doi: 10.1242/jcs.126482. Epub 2013 Dec 11.

36.

C. elegans sensing of and entrainment along obstacles require different neurons at different body locations.

Nam SW, Qian C, Kim SH, van Noort D, Chiam KH, Park S.

Sci Rep. 2013 Nov 27;3:3247. doi: 10.1038/srep03247.

37.

Bacterial tethering analysis reveals a "run-reverse-turn" mechanism for Pseudomonas species motility.

Qian C, Wong CC, Swarup S, Chiam KH.

Appl Environ Microbiol. 2013 Aug;79(15):4734-43. doi: 10.1128/AEM.01027-13. Epub 2013 May 31.

38.

Anisotropic rigidity sensing on grating topography directs human mesenchymal stem cell elongation.

Wong ST, Teo SK, Park S, Chiam KH, Yim EK.

Biomech Model Mechanobiol. 2014 Jan;13(1):27-39. doi: 10.1007/s10237-013-0483-2. Epub 2013 Mar 26.

PMID:
23529613
39.

A computational model of amoeboid cell migration.

Lim FY, Koon YL, Chiam KH.

Comput Methods Biomech Biomed Engin. 2013 Oct;16(10):1085-95. doi: 10.1080/10255842.2012.757598. Epub 2013 Jan 23.

PMID:
23342988
40.

Cellular response to substrate rigidity is governed by either stress or strain.

Yip AK, Iwasaki K, Ursekar C, Machiyama H, Saxena M, Chen H, Harada I, Chiam KH, Sawada Y.

Biophys J. 2013 Jan 8;104(1):19-29. doi: 10.1016/j.bpj.2012.11.3805. Epub 2013 Jan 8.

41.

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

Chiam K, Ryan NK, Ricciardelli C, Day TK, Buchanan G, Ochnik AM, Murti K, Selth LA; Australian Prostate Cancer BioResource, Butler LM, Tilley WD, Bianco-Miotto T.

Prostate. 2013 Jan;73(2):182-93. doi: 10.1002/pros.22554. Epub 2012 Jul 10.

PMID:
22782870
42.

Transcription factor oscillations induce differential gene expressions.

Wee KB, Yio WK, Surana U, Chiam KH.

Biophys J. 2012 Jun 6;102(11):2413-23. doi: 10.1016/j.bpj.2012.04.023. Epub 2012 Jun 5.

43.

Epigenetic biomarkers in prostate cancer: Current and future uses.

Chiam K, Ricciardelli C, Bianco-Miotto T.

Cancer Lett. 2014 Jan 28;342(2):248-56. doi: 10.1016/j.canlet.2012.02.011. Epub 2012 Mar 3. Review.

PMID:
22391123
44.

Mechanochemical model of cell migration on substrates of varying stiffness.

Lai T, Chiam KH.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Dec;84(6 Pt 1):061907. Epub 2011 Dec 9.

PMID:
22304116
45.

Hydrodynamic interaction between two nonspherical capsules in shear flow.

Le DV, Chiam KH.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Nov;84(5 Pt 2):056322. Epub 2011 Nov 23.

PMID:
22181513
46.

Myosin concentration underlies cell size-dependent scalability of actomyosin ring constriction.

Calvert ME, Wright GD, Leong FY, Chiam KH, Chen Y, Jedd G, Balasubramanian MK.

J Cell Biol. 2011 Nov 28;195(5):799-813. doi: 10.1083/jcb.201101055.

47.

Investigating circular dorsal ruffles through varying substrate stiffness and mathematical modeling.

Zeng Y, Lai T, Koh CG, LeDuc PR, Chiam KH.

Biophys J. 2011 Nov 2;101(9):2122-30. doi: 10.1016/j.bpj.2011.09.047. Epub 2011 Nov 1.

48.

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.

Chiam K, Centenera MM, Butler LM, Tilley WD, Bianco-Miotto T.

PLoS One. 2011;6(9):e25634. doi: 10.1371/journal.pone.0025634. Epub 2011 Sep 28.

49.

Divergent strategies for controlling the nuclear membrane satisfy geometric constraints during nuclear division.

Yam C, He Y, Zhang D, Chiam KH, Oliferenko S.

Curr Biol. 2011 Aug 9;21(15):1314-9. doi: 10.1016/j.cub.2011.06.052. Epub 2011 Jul 28.

50.

Bacillus anthracis tubulin-related protein Ba-TubZ assembles force-generating polymers.

Srinivasan R, Mishra M, Leong FY, Chiam KH, Balasubramanian M.

Cytoskeleton (Hoboken). 2011 Sep;68(9):501-11. doi: 10.1002/cm.20526. Epub 2011 Aug 9.

PMID:
21780309

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