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Site-Selective N-Methylation of 5,15-Diazaporphyrins: Reactive Cationic Porphyrinoids that Provide Isoporphyrin Analogues.

Chia WX, Nishijo M, Kang S, Oh J, Nishimura T, Omori H, Longevial JF, Miyake Y, Kim D, Shinokubo H.

Chemistry. 2019 Dec 2. doi: 10.1002/chem.201905402. [Epub ahead of print]


Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination.

Chen PM, Pan WY, Wu CY, Yeh CY, Korupalli C, Luo PK, Chou CJ, Chia WT, Sung HW.

Biomaterials. 2020 Feb;230:119629. doi: 10.1016/j.biomaterials.2019.119629. Epub 2019 Nov 15.


Robust dengue virus infection in bat cells and limited innate immune responses coupled with positive serology from bats in IndoMalaya and Australasia.

Irving AT, Rozario P, Kong PS, Luko K, Gorman JJ, Hastie ML, Chia WN, Mani S, Lee BP, Smith GJD, Mendenhall IH, Larman HB, Elledge SJ, Wang LF.

Cell Mol Life Sci. 2019 Jul 27. doi: 10.1007/s00018-019-03242-x. [Epub ahead of print]


The Potential of Carnosine in Brain-Related Disorders: A Comprehensive Review of Current Evidence.

Schön M, Mousa A, Berk M, Chia WL, Ukropec J, Majid A, Ukropcová B, de Courten B.

Nutrients. 2019 May 28;11(6). pii: E1196. doi: 10.3390/nu11061196. Review.


Block Compressive Sensing (BCS) Based Low Complexity, Energy Efficient Visual Sensor Platform with Joint Multi-Phase Decoder (JMD).

Ebrahim M, Chia WC, Adil SH, Raza K.

Sensors (Basel). 2019 May 19;19(10). pii: E2309. doi: 10.3390/s19102309.


Malaysian Females With Congenital Adrenal Hyperplasia: Surgical Outcomes and Attitudes.

Zainuddin AA, Grover SR, Soon CH, Nur Azurah AG, Mahdy ZA, Wu LL, Rasat R, Harun F, Chia WY, Shamsuddin K.

Front Pediatr. 2019 Apr 17;7:144. doi: 10.3389/fped.2019.00144. eCollection 2019.


Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host.

Ahn M, Anderson DE, Zhang Q, Tan CW, Lim BL, Luko K, Wen M, Chia WN, Mani S, Wang LC, Ng JHJ, Sobota RM, Dutertre CA, Ginhoux F, Shi ZL, Irving AT, Wang LF.

Nat Microbiol. 2019 May;4(5):789-799. doi: 10.1038/s41564-019-0371-3. Epub 2019 Feb 25.


Multiplex STR panel for assessment of chimerism following hematopoietic stem cell transplantation (HSCT).

Chia WC, Khoo TS, Abdul Wahid SFS, Razak NFA, Alauddin H, Raja Sabudin RZA, Othman A, Hassan R, Hussin NH.

Ann Hematol. 2019 May;98(5):1279-1291. doi: 10.1007/s00277-019-03626-w. Epub 2019 Feb 19.


Diazachlorin and diazabacteriochlorin for one- and two-photon photodynamic therapy.

Longevial JF, Yamaji A, Aggad D, Kim G, Chia WX, Nishimura T, Miyake Y, Clément S, Oh J, Daurat M, Nguyen C, Kim D, Gary-Bobo M, Richeter S, Shinokubo H.

Chem Commun (Camb). 2018 Dec 6;54(98):13829-13832. doi: 10.1039/c8cc07489e.


Exploring the genome and transcriptome of the cave nectar bat Eonycteris spelaea with PacBio long-read sequencing.

Wen M, Ng JHJ, Zhu F, Chionh YT, Chia WN, Mendenhall IH, Lee BP, Irving AT, Wang LF.

Gigascience. 2018 Oct 1;7(10). doi: 10.1093/gigascience/giy116.


An In Situ Depot for Continuous Evolution of Gaseous H2 Mediated by a Magnesium Passivation/Activation Cycle for Treating Osteoarthritis.

Wan WL, Lin YJ, Shih PC, Bow YR, Cui Q, Chang Y, Chia WT, Sung HW.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9875-9879. doi: 10.1002/anie.201806159. Epub 2018 Jul 6.


Analysis of Reasons for Potentially Preventable Hospital Transfers Using the Modified INTERACT-II Tool.

Magpantay GC, Toh HJ, Low JA, Chia WK.

J Am Med Dir Assoc. 2018 Feb;19(2):181-182. doi: 10.1016/j.jamda.2017.11.010. Epub 2017 Dec 26. No abstract available.


Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in recurrent ovarian cancer with peritoneal metastasis: a prospective registry study on 41 patients.

Teo MCC, Chia CS, Lim C, Tan GHC, Chia WK, Soo KC.

Pleura Peritoneum. 2017 Dec 1;2(4):171-179. doi: 10.1515/pp-2017-0021.


Performance evaluation of Cepheid Xpert Norovirus kit with a user-modified protocol.

Wong RS, Yeo F, Chia WT, Lee CK, Leong MH, Ng CW, Poon KS, Yan GZ, Chiu LL, Yan BJ, Jureen R, Koay ES, Lee HK.

J Med Virol. 2018 Mar;90(3):485-489. doi: 10.1002/jmv.24981. Epub 2017 Nov 14.


Comparison of arthroplasty vs. osteosynthesis for displaced femoral neck fractures: a meta-analysis.

Tseng FJ, Chia WT, Pan RY, Lin LC, Shen HC, Wang CH, Shyu JF, Weng CF.

J Orthop Surg Res. 2017 Sep 15;12(1):131. doi: 10.1186/s13018-017-0629-5.


In Situ Nanoreactor for Photosynthesizing H2 Gas To Mitigate Oxidative Stress in Tissue Inflammation.

Wan WL, Lin YJ, Chen HL, Huang CC, Shih PC, Bow YR, Chia WT, Sung HW.

J Am Chem Soc. 2017 Sep 20;139(37):12923-12926. doi: 10.1021/jacs.7b07492. Epub 2017 Sep 11.


Comparison of health state values derived from patients and individuals from the general population.

Gandhi M, Tan RS, Ng R, Choo SP, Chia WK, Toh CK, Lam C, Lee PT, Latt NKZ, Rand-Hendriksen K, Cheung YB, Luo N.

Qual Life Res. 2017 Dec;26(12):3353-3363. doi: 10.1007/s11136-017-1683-5. Epub 2017 Aug 14.


Effect of low-dose aspirin use on survival of patients with gastrointestinal malignancies; an observational study.

Frouws MA, Bastiaannet E, Langley RE, Chia WK, van Herk-Sukel MP, Lemmens VE, Putter H, Hartgrink HH, Bonsing BA, Van de Velde CJ, Portielje JE, Liefers GJ.

Br J Cancer. 2017 Jan;116(3):405-413. doi: 10.1038/bjc.2016.425. Epub 2017 Jan 10.


Dismal outcome of therapy-related myeloid neoplasm associated with complex aberrant karyotypes and monosomal karyotype: a case report.

Tang YL, Chia WK, Yap EC, Julia MI, Leong CF, Salwati S, Wong CL.

Malays J Pathol. 2016 Dec;38(3):315-319.


Ex Vivo and In Vivo Mice Models to Study Blastocystis spp. Adhesion, Colonization and Pathology: Closer to Proving Koch's Postulates.

Ajjampur SS, Png CW, Chia WN, Zhang Y, Tan KS.

PLoS One. 2016 Aug 10;11(8):e0160458. doi: 10.1371/journal.pone.0160458. eCollection 2016.


Neutralizing Antibodies against Plasmodium falciparum Associated with Successful Cure after Drug Therapy.

Goh YS, Peng K, Chia WN, Siau A, Chotivanich K, Gruner AC, Preiser P, Mayxay M, Pukrittayakamee S, Sriprawat K, Nosten F, White NJ, Renia L.

PLoS One. 2016 Jul 18;11(7):e0159347. doi: 10.1371/journal.pone.0159347. eCollection 2016.


Imaging flow cytometry for the screening of compounds that disrupt the Plasmodium falciparum digestive vacuole.

Chia WN, Lee YQ, Tan KS.

Methods. 2017 Jan 1;112:211-220. doi: 10.1016/j.ymeth.2016.07.002. Epub 2016 Jul 5.


Influence of 3-Chloroaniline on the Biofilm Lifestyle of Comamonas testosteroni and Its Implications on Bioaugmentation.

Wu Y, Mohanty A, Chia WS, Cao B.

Appl Environ Microbiol. 2016 Jun 30;82(14):4401-4409. doi: 10.1128/AEM.00874-16. Print 2016 Jul 15.


Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents.

Boudhar A, Ng XW, Loh CY, Chia WN, Tan ZM, Nosten F, Dymock BW, Tan KS.

Eur J Med Chem. 2016 Aug 25;119:231-49. doi: 10.1016/j.ejmech.2016.04.058. Epub 2016 Apr 26.


Smartphone spectrometer for colorimetric biosensing.

Wang Y, Liu X, Chen P, Tran NT, Zhang J, Chia WS, Boujday S, Liedberg B.

Analyst. 2016 May 23;141(11):3233-8. doi: 10.1039/c5an02508g.


Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection.

Peng K, Goh YS, Siau A, Franetich JF, Chia WN, Ong AS, Malleret B, Wu YY, Snounou G, Hermsen CC, Adams JH, Mazier D, Preiser PR, Sauerwein RW, Grüner AC, Rénia L.

Cell Microbiol. 2016 Dec;18(12):1739-1750. doi: 10.1111/cmi.12608. Epub 2016 May 27.


Immunotherapy for nasopharyngeal cancer-a review.

Jain A, Chia WK, Toh HC.

Chin Clin Oncol. 2016 Apr;5(2):22. doi: 10.21037/cco.2016.03.08. Review.


An Implantable Depot That Can Generate Oxygen in Situ for Overcoming Hypoxia-Induced Resistance to Anticancer Drugs in Chemotherapy.

Huang CC, Chia WT, Chung MF, Lin KJ, Hsiao CW, Jin C, Lim WH, Chen CC, Sung HW.

J Am Chem Soc. 2016 Apr 27;138(16):5222-5. doi: 10.1021/jacs.6b01784. Epub 2016 Apr 13.


Overcoming Chloroquine Resistance in Malaria: Design, Synthesis, and Structure-Activity Relationships of Novel Hybrid Compounds.

Boudhar A, Ng XW, Loh CY, Chia WN, Tan ZM, Nosten F, Dymock BW, Tan KS.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3076-89. doi: 10.1128/AAC.02476-15. Print 2016 May.


Double Philadelphia chromosome-positive B acute lymphoblastic leukaemia in an elderly patient.

Tang YL, Raja Sabudin RZ, Leong CF, Ko CC, Chia WK, Salwati S, Wong CL.

Malays J Pathol. 2015 Dec;37(3):275-9.


Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum.

Wang J, Zhang CJ, Chia WN, Loh CC, Li Z, Lee YM, He Y, Yuan LX, Lim TK, Liu M, Liew CX, Lee YQ, Zhang J, Lu N, Lim CT, Hua ZC, Liu B, Shen HM, Tan KS, Lin Q.

Nat Commun. 2015 Dec 22;6:10111. doi: 10.1038/ncomms10111.


Controlled Release of an Anti-inflammatory Drug Using an Ultrasensitive ROS-Responsive Gas-Generating Carrier for Localized Inflammation Inhibition.

Chung MF, Chia WT, Wan WL, Lin YJ, Sung HW.

J Am Chem Soc. 2015 Oct 7;137(39):12462-5. doi: 10.1021/jacs.5b08057. Epub 2015 Sep 24.


Immunization with the MAEBL M2 Domain Protects against Lethal Plasmodium yoelii Infection.

Leite JA, Bargieri DY, Carvalho BO, Albrecht L, Lopes SC, Kayano AC, Farias AS, Chia WN, Claser C, Malleret B, Russell B, Castiñeiras C, Santos LM, Brocchi M, Wunderlich G, Soares IS, Rodrigues MM, Rénia L, Costa FT.

Infect Immun. 2015 Oct;83(10):3781-92. doi: 10.1128/IAI.00262-15. Epub 2015 Jul 13.


Carbon Monoxide Inhibits Receptor Activator of NF-κB (RANKL)-Induced Osteoclastogenesis.

Tseng FJ, Chia WT, Wang CH, Shyu JF, Gou GH, Shui HA, Sytwu HK, Pan RY, Weng CF.

Cell Physiol Biochem. 2015;36(3):1250-8. doi: 10.1159/000430294. Epub 2015 Jul 1.


A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug Resistance.

Chung MF, Liu HY, Lin KJ, Chia WT, Sung HW.

Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9890-3. doi: 10.1002/anie.201504444. Epub 2015 Jul 1.


Expression and localisation of brain-type organic cation transporter (BOCT/24p3R/LCN2R) in the normal rat hippocampus and after kainate-induced excitotoxicity.

Chia WJ, Tan FC, Ong WY, Dawe GS.

Neurochem Int. 2015 Aug;87:43-59. doi: 10.1016/j.neuint.2015.04.009. Epub 2015 May 21.


Photothermal tumor ablation in mice with repeated therapy sessions using NIR-absorbing micellar hydrogels formed in situ.

Hsiao CW, Chuang EY, Chen HL, Wan D, Korupalli C, Liao ZX, Chiu YL, Chia WT, Lin KJ, Sung HW.

Biomaterials. 2015 Jul;56:26-35. doi: 10.1016/j.biomaterials.2015.03.060. Epub 2015 Apr 15.


A new series of kinked liquid crystals: 2-(6-alkoxynaphthalen-2-yl)-6-methoxyquinolines.

Chia WL, Liu CW.

Int J Mol Sci. 2015 Apr 2;16(4):7520-34. doi: 10.3390/ijms16047520.


Post-operative aspirin use and colorectal cancer-specific survival in patients with stage I-III colorectal cancer.

Goh CH, Leong WQ, Chew MH, Pan YS, Tony LK, Chew L, Tan IB, Toh HC, Tang CL, Fu WP, Chia WK.

Anticancer Res. 2014 Dec;34(12):7407-14. Erratum in: Anticancer Res. 2015 Feb;35(2):1219. Goh, Hin Hock [corrected to Goh, Chin Hock].


A rapid drug release system with a NIR light-activated molecular switch for dual-modality photothermal/antibiotic treatments of subcutaneous abscesses.

Chiang WL, Lin TT, Sureshbabu R, Chia WT, Hsiao HC, Liu HY, Yang CM, Sung HW.

J Control Release. 2015 Feb 10;199:53-62. doi: 10.1016/j.jconrel.2014.12.011. Epub 2014 Dec 11.


Novel approaches to identify protective malaria vaccine candidates.

Chia WN, Goh YS, Rénia L.

Front Microbiol. 2014 Nov 17;5:586. doi: 10.3389/fmicb.2014.00586. eCollection 2014. Review.


Cost-effectiveness of aspirin adjuvant therapy in early stage colorectal cancer in older patients.

Soon SS, Chia WK, Chan ML, Ho GF, Jian X, Deng YH, Tan CS, Sharma A, Segelov E, Mehta S, Ali R, Toh HC, Wee HL.

PLoS One. 2014 Sep 24;9(9):e107866. doi: 10.1371/journal.pone.0107866. eCollection 2014.


Dendritic fibromyxolipoma: a variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence.

Wong YP, Chia WK, Low SF, Mohamed-Haflah NH, Sharifah NA.

Pathol Int. 2014 Jul;64(7):346-51. doi: 10.1111/pin.12176. Review.


Injectable microbeads with a thermo-responsive shell and a pH-responsive core as a dual-switch-controlled release system.

Chiang WL, Hu YC, Liu HY, Hsiao CW, Sureshbabu R, Yang CM, Chung MF, Chia WT, Sung HW.

Small. 2014 Oct 29;10(20):4100-5. doi: 10.1002/smll.201400842. Epub 2014 Jun 30.


Validation of a chloroquine-induced cell death mechanism for clinical use against malaria.

Ch'ng JH, Lee YQ, Gun SY, Chia WN, Chang ZW, Wong LK, Batty KT, Russell B, Nosten F, Renia L, Tan KS.

Cell Death Dis. 2014 Jun 26;5:e1305. doi: 10.1038/cddis.2014.265.


Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesis.

Tseng FJ, Chia WT, Shyu JF, Gou GH, Sytwu HK, Hsia CW, Tseng MJ, Pan RY.

BMC Syst Biol. 2014 May 18;8:57. doi: 10.1186/1752-0509-8-57.


Inflammation-induced drug release by using a pH-responsive gas-generating hollow-microsphere system for the treatment of osteomyelitis.

Chung MF, Chia WT, Liu HY, Hsiao CW, Hsiao HC, Yang CM, Sung HW.

Adv Healthc Mater. 2014 Nov;3(11):1854-61. doi: 10.1002/adhm.201400158. Epub 2014 May 2.


Enhanced anti-tumor activity of triptolide in combination with irradiation for the treatment of oral cancer.

Chen YW, Lin GJ, Hueng DY, Huang SH, Chia WT, Shieh YS, Ma KH, Sytwu HK.

Planta Med. 2014 Mar;80(4):255-61. doi: 10.1055/s-0033-1360315. Epub 2014 Feb 7.


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