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Items: 1 to 50 of 664

1.

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers.

Ghadami SA, Chia S, Ruggeri FS, Meisl G, Bemporad F, Habchi J, Cascella R, Dobson CM, Vendruscolo M, Knowles TPJ, Chiti F.

Biomacromolecules. 2020 Feb 17. doi: 10.1021/acs.biomac.9b01475. [Epub ahead of print]

PMID:
32011129
2.

An improved method for the rescue of recombinant Newcastle disease virus.

Cheow PS, Tan TK, Song AA, Yusoff K, Chia SL.

Biotechniques. 2020 Feb;68(2):96-100. doi: 10.2144/btn-2019-0110. Epub 2020 Jan 15.

3.

The RNA-binding protein HuR is a negative regulator in adipogenesis.

Siang DTC, Lim YC, Kyaw AMM, Win KN, Chia SY, Degirmenci U, Hu X, Tan BC, Walet ACE, Sun L, Xu D.

Nat Commun. 2020 Jan 10;11(1):213. doi: 10.1038/s41467-019-14001-8.

4.

Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.

van de Wetering C, Aboushousha R, Manuel AM, Chia SB, Erickson C, MacPherson MB, van der Velden JL, Anathy V, Dixon AE, Irvin CG, Poynter ME, van der Vliet A, Wouters EFM, Reynaert NL, Janssen-Heininger YMW.

J Immunol. 2020 Feb 15;204(4):763-774. doi: 10.4049/jimmunol.1901086. Epub 2020 Jan 10.

5.

Effects of continuing use of aspirin on blood loss in patients who underwent unilateral total knee arthroplasty.

Hang G, Chen JY, Yew AKS, Pang HN, Jin DTK, Chia SL, Lo NN, Yeo SJ.

J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019894390. doi: 10.1177/2309499019894390.

PMID:
31916487
6.

Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis.

Lavoie JM, Mitchell T, Lee SE, Deol B, Chia SK, Gelmon KA, Kollmannsberger CK, Tinker AV, Jones SJM, Marra M, Laskin J, Renouf DJ.

Invest New Drugs. 2020 Jan 6. doi: 10.1007/s10637-020-00892-8. [Epub ahead of print]

PMID:
31907737
7.

Metallointercalator [Ru(dppz)2(PIP)]2+ Renders BRCA Wild-Type Triple-Negative Breast Cancer Cells Hypersensitive to PARP Inhibition.

Yusoh NA, Leong SW, Chia SL, Harun SN, Rahman MBA, Vallis KA, Gill MR, Ahmad H.

ACS Chem Biol. 2020 Jan 14. doi: 10.1021/acschembio.9b00843. [Epub ahead of print]

PMID:
31898884
8.

Frailty and functional decline after emergency abdominal surgery in the elderly: a prospective cohort study.

Tan HL, Chia STX, Nadkarni NV, Ang SY, Seow DCC, Wong TH.

World J Emerg Surg. 2019 Dec 30;14:62. doi: 10.1186/s13017-019-0280-z. eCollection 2019.

9.

Microalgal Protein Extraction From Chlorella vulgaris FSP-E Using Triphasic Partitioning Technique With Sonication.

Chia SR, Chew KW, Zaid HFM, Chu DT, Tao Y, Show PL.

Front Bioeng Biotechnol. 2019 Dec 6;7:396. doi: 10.3389/fbioe.2019.00396. eCollection 2019.

10.

Increased constraint of rotating hinge knee prosthesis is associated with poorer clinical outcomes as compared to constrained condylar knee prosthesis in total knee arthroplasty.

Lim JBT, Pang HN, Tay KJD, Chia SL, Lo NN, Yeo SJ.

Eur J Orthop Surg Traumatol. 2019 Dec 16. doi: 10.1007/s00590-019-02598-x. [Epub ahead of print]

PMID:
31844984
11.

Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer.

Slamon DJ, Neven P, Chia S, Fasching PA, De Laurentiis M, Im SA, Petrakova K, Bianchi GV, Esteva FJ, Martín M, Nusch A, Sonke GS, De la Cruz-Merino L, Beck JT, Pivot X, Sondhi M, Wang Y, Chakravartty A, Rodriguez-Lorenc K, Taran T, Jerusalem G.

N Engl J Med. 2020 Feb 6;382(6):514-524. doi: 10.1056/NEJMoa1911149. Epub 2019 Dec 11.

PMID:
31826360
12.

A retrospective review of tuberculosis exposure among health care workers in a tertiary hospital.

Chia SZG, How KBM, Chlebicki MP, Ling ML, Gan WH.

Am J Infect Control. 2019 Dec 2. pii: S0196-6553(19)30906-X. doi: 10.1016/j.ajic.2019.10.014. [Epub ahead of print]

PMID:
31806237
13.

Impact of pathologic complete response on survival after neoadjuvant chemotherapy in early-stage breast cancer: a population-based analysis.

LeVasseur N, Sun J, Gondara L, Diocee R, Speers C, Lohrisch C, Chia S.

J Cancer Res Clin Oncol. 2020 Feb;146(2):529-536. doi: 10.1007/s00432-019-03083-y. Epub 2019 Nov 18.

PMID:
31741041
14.

Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.

Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team, Marra MA, Hansen C, Shah SP, Aparicio S.

Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026.

15.

Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.

Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger YMW.

Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6.

PMID:
31693398
16.

Planning mass eradication of Helicobacter pylori infection for indigenous Taiwanese peoples to reduce gastric cancer.

Bair MJ, Chuang SL, Lei WY, Chen CL, Tian HW, Chiang TH, Su WW, Lin CC, Chung Lo YT, Jou YY, Wu CY, Chia SL, Wu MS, Chen HH, Chu CH, Lee YC, Wang YW.

J Gastroenterol Hepatol. 2019 Nov 1. doi: 10.1111/jgh.14898. [Epub ahead of print]

PMID:
31677184
17.

Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.

Delivoria DC, Chia S, Habchi J, Perni M, Matis I, Papaevgeniou N, Reczko M, Chondrogianni N, Dobson CM, Vendruscolo M, Skretas G.

Sci Adv. 2019 Oct 16;5(10):eaax5108. doi: 10.1126/sciadv.aax5108. eCollection 2019 Oct.

18.

Effects of High Anxiety Scores on Surgical and Overall Treatment Plan in Patients with Breast Cancer Treated with Neoadjuvant Therapy.

LeVasseur N, Li H, Cheung W, Myers P, Mckevitt E, Warburton R, Willemsma KA, Tan AD, Chia S, Simmons C.

Oncologist. 2019 Oct 15. pii: theoncologist.2019-0512. doi: 10.1634/theoncologist.2019-0512. [Epub ahead of print]

19.

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer.

Mohamed Amin Z, Che Ani MA, Tan SW, Yeap SK, Alitheen NB, Syed Najmuddin SUF, Kalyanasundram J, Chan SC, Veerakumarasivam A, Chia SL, Yusoff K.

Sci Rep. 2019 Sep 30;9(1):13999. doi: 10.1038/s41598-019-50222-z.

20.

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy.

Ruggeri FS, Šneideris T, Chia S, Vendruscolo M, Knowles TPJ.

J Vis Exp. 2019 Sep 12;(151). doi: 10.3791/60108.

PMID:
31566623
21.

An efficient and rapid method to extract and purify protein - Liquid Triphasic Flotation system.

Chia SR, Mak KY, Khaw YJ, Suhaidi N, Chew KW, Show PL.

Bioresour Technol. 2019 Dec;294:122158. doi: 10.1016/j.biortech.2019.122158. Epub 2019 Sep 17.

PMID:
31550634
22.

Effect of Dietary Replacement of Fishmeal by Insect Meal on Growth Performance, Blood Profiles and Economics of Growing Pigs in Kenya.

Chia SY, Tanga CM, Osuga IM, Alaru AO, Mwangi DM, Githinji M, Subramanian S, Fiaboe KKM, Ekesi S, van Loon JJA, Dicke M.

Animals (Basel). 2019 Sep 20;9(10). pii: E705. doi: 10.3390/ani9100705.

23.

Virotherapy: Current Trends and Future Prospects for Treatment of Colon and Rectal Malignancies.

Lee CL, Veeramani S, Molouki A, Lim SHE, Thomas W, Chia SL, Yusoff K.

Cancer Invest. 2019;37(8):393-414. doi: 10.1080/07357907.2019.1660887. Epub 2019 Sep 10. Review.

PMID:
31502477
24.

Association between serum heavy metals and prostate cancer risk - A multiple metal analysis.

Lim JT, Tan YQ, Valeri L, Lee J, Geok PP, Chia SE, Ong CN, Seow WJ.

Environ Int. 2019 Nov;132:105109. doi: 10.1016/j.envint.2019.105109. Epub 2019 Sep 3.

25.

A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229).

Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L.

Oncologist. 2019 Nov;24(11):1439-1445. doi: 10.1634/theoncologist.2019-0321. Epub 2019 Aug 16.

26.

Recent Developments of Reverse Micellar Techniques for Lysozyme, Bovine Serum Albumin, and Bromelain Extraction.

Chia SR, Tang MSY, Chow YH, Ooi CW, Rambabu K, Zhu L, Show PL.

Mol Biotechnol. 2019 Oct;61(10):715-724. doi: 10.1007/s12033-019-00200-7. Review.

PMID:
31350687
27.

Concomitant pediatric abdominal and pulmonary tuberculosis.

Kuo HC, Chen SC, Lin HK, Chia ST, Leung JH.

Pediatr Neonatol. 2019 Dec;60(6):695-696. doi: 10.1016/j.pedneo.2019.06.006. Epub 2019 Jun 28. No abstract available.

28.

Efficacy of Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in ER-positive Breast Cancer: Results From a Prospective Institutional Database.

LeVasseur N, Willemsma KA, Li H, Gondara L, Yip WC, Illmann C, Chia SK, Simmons C.

Clin Breast Cancer. 2019 Dec;19(6):e683-e689. doi: 10.1016/j.clbc.2019.05.020. Epub 2019 Jun 11.

PMID:
31279611
29.

Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications.

Chia SR, Chew KW, Show PL, Xia A, Ho SH, Lim JW.

Bioresour Technol. 2019 Oct;289:121727. doi: 10.1016/j.biortech.2019.121727. Epub 2019 Jun 29.

PMID:
31279318
30.

Functional outcome and quality of life in patients with hip fracture after total knee arthroplasty.

Koh DTS, Chen JY, Yew AKS, Chong HC, Hao Y, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019852338. doi: 10.1177/2309499019852338.

PMID:
31204571
31.

Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?

LeVasseur N, Chia S.

Br J Cancer. 2019 Jul;121(1):1-2. doi: 10.1038/s41416-019-0484-8. Epub 2019 Jun 7.

PMID:
31171836
32.

Development and Validation of a Self-Assessment Tool for an Integrative Model of Health Promotion in Hospitals: Taiwan's Experience.

Wang YW, Chia SL, Chou CM, Chen MS, Pelikan JM, Chu C, Wang MH, Lee CB.

Int J Environ Res Public Health. 2019 Jun 1;16(11). pii: E1953. doi: 10.3390/ijerph16111953.

33.

Liquid biphasic flotation for the purification of C-phycocyanin from Spirulina platensis microalga.

Chew KW, Chia SR, Krishnamoorthy R, Tao Y, Chu DT, Show PL.

Bioresour Technol. 2019 Sep;288:121519. doi: 10.1016/j.biortech.2019.121519. Epub 2019 May 20.

PMID:
31128541
34.

Clinical outcomes and patient satisfaction following revision of failed unicompartmental knee arthroplasty to total knee arthroplasty are as good as a primary total knee arthroplasty.

Lim JBT, Pang HN, Tay KJD, Chia SL, Lo NN, Yeo SJ.

Knee. 2019 Aug;26(4):847-852. doi: 10.1016/j.knee.2019.04.016. Epub 2019 May 18.

PMID:
31113700
35.

Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor-positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT).

McCartney A, Biagioni C, Schiavon G, Bergqvist M, Mattsson K, Migliaccio I, Benelli M, Romagnoli D, Bonechi M, Boccalini G, Pestrin M, Galardi F, De Luca F, Biganzoli L, Piccart M, Gradishar WJ, Chia S, Di Leo A, Malorni L.

Eur J Cancer. 2019 Jun;114:55-66. doi: 10.1016/j.ejca.2019.04.002. Epub 2019 May 3.

PMID:
31059974
36.

The Singapore Heart Failure Risk Score: Prediction of Survival in Southeast Asian Patients.

Yap J, Chia SY, Lim FY, Allen JC, Teo L, Sim D, Go YY, Jaufeerally FR, Seow M, Kwok B, Liew R, Lam CS, Ching CK.

Ann Acad Med Singapore. 2019 Mar;48(3):86-94.

37.

Establishing an allied health professional delivered selective laser trabeculoplasty service in Scotland.

Chadwick O, Chia SN, Rotchford A.

Ophthalmic Physiol Opt. 2019 May;39(3):216-223. doi: 10.1111/opo.12611.

PMID:
30994202
38.

Current Landscape of Immunotherapy in Breast Cancer: A Review.

Adams S, Gatti-Mays ME, Kalinsky K, Korde LA, Sharon E, Amiri-Kordestani L, Bear H, McArthur HL, Frank E, Perlmutter J, Page DB, Vincent B, Hayes JF, Gulley JL, Litton JK, Hortobagyi GN, Chia S, Krop I, White J, Sparano J, Disis ML, Mittendorf EA.

JAMA Oncol. 2019 Apr 11. doi: 10.1001/jamaoncol.2018.7147. [Epub ahead of print]

PMID:
30973611
39.

PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial.

Chia SKL, Martin M, Holmes FA, Ejlertsen B, Delaloge S, Moy B, Iwata H, von Minckwitz G, Mansi J, Barrios CH, Gnant M, Tomašević Z, Denduluri N, Šeparović R, Kim SB, Jakobsen EH, Harvey V, Robert N, Smith J 2nd, Harker G, Zhang B, Eli LD, Ye Y, Lalani AS, Buyse M, Chan A.

Breast Cancer Res. 2019 Mar 11;21(1):39. doi: 10.1186/s13058-019-1115-2.

40.

Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III Trial.

Rothé F, Silva MJ, Venet D, Campbell C, Bradburry I, Rouas G, de Azambuja E, Maetens M, Fumagalli D, Rodrik-Outmezguine V, Di Cosimo S, Rosa D, Chia S, Wardley A, Ueno T, Janni W, Huober J, Baselga J, Piccart M, Loi S, Sotiriou C, Dawson SJ, Ignatiadis M.

Clin Cancer Res. 2019 Jun 15;25(12):3581-3588. doi: 10.1158/1078-0432.CCR-18-2521. Epub 2019 Mar 12.

PMID:
30862692
41.

Prediction of Survival in Asian Patients Hospitalized With Heart Failure: Validation of the OPTIMIZE-HF Risk Score.

Yap J, Lim FY, Chia SY, Allen JC Jr, Jaufeerally FR, Macdonald MR, Chai P, Loh SY, Lim P, Zaw MWW, Teo L, Sim D, Lam CSP.

J Card Fail. 2019 Jul;25(7):571-575. doi: 10.1016/j.cardfail.2019.02.016. Epub 2019 Feb 26.

PMID:
30822512
42.

Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.

Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW.

Antioxid Redox Signal. 2019 Nov 10;31(14):1070-1091. doi: 10.1089/ars.2019.7752. Epub 2019 Apr 5.

PMID:
30799628
43.

The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: A systematic review and network meta-analysis.

Xu S, Chen JY, Zheng Q, Lo NN, Chia SL, Tay KJD, Pang HN, Shi L, Chan ESY, Yeo SJ.

Thromb Res. 2019 Apr;176:61-66. doi: 10.1016/j.thromres.2019.02.006. Epub 2019 Feb 11.

PMID:
30776688
44.

The influence of obesity on clinical outcomes of fixed-bearing unicompartmental knee arthroplasty: a ten-year follow-up study.

Xu S, Lim WJ, Chen JY, Lo NN, Chia SL, Tay DKJ, Hao Y, Yeo SJ.

Bone Joint J. 2019 Feb;101-B(2):213-220. doi: 10.1302/0301-620X.101B2.BJJ-2018-0969.R2.

PMID:
30700121
45.

Effects of neratinib on health-related quality of life in women with HER2-positive early-stage breast cancer: longitudinal analyses from the randomized phase III ExteNET trial.

Delaloge S, Cella D, Ye Y, Buyse M, Chan A, Barrios CH, Holmes FA, Mansi J, Iwata H, Ejlertsen B, Moy B, Chia SKL, Gnant M, Smichkoska S, Ciceniene A, Martinez N, Filipović S, Ben-Baruch NE, Joy AA, Langkjer ST, Senecal F, de Boer RH, Moran S, Yao B, Bryce R, Auerbach A, Fallowfield L, Martin M.

Ann Oncol. 2019 Apr 1;30(4):567-574. doi: 10.1093/annonc/mdz016.

PMID:
30689703
46.

Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial.

Haldar S, Pakkiri LS, Lim J, Chia SC, Ponnalagu S, Drum CL, Henry CJ.

Front Physiol. 2019 Jan 9;9:1899. doi: 10.3389/fphys.2018.01899. eCollection 2018.

47.

Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.

Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM.

Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5.

48.

Slide-free imaging of hematoxylin-eosin stained whole-mount tissues using combined third-harmonic generation and three-photon fluorescence microscopy.

Sun CK, Kao CT, Wei ML, Chia SH, Kärtner FX, Ivanov A, Liao YH.

J Biophotonics. 2019 May;12(5):e201800341. doi: 10.1002/jbio.201800341. Epub 2019 Feb 27.

PMID:
30636033
49.

Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.

Ahn M, Lee BI, Chia S, Habchi J, Kumita JR, Vendruscolo M, Dobson CM, Park CB.

Chem Commun (Camb). 2019 Jan 25;55(8):1152-1155. doi: 10.1039/c8cc09288e. Epub 2019 Jan 11.

PMID:
30632567
50.

Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial.

Shi W, Jiang T, Nuciforo P, Hatzis C, Holmes E, Harbeck N, Sotiriou C, Peña L, Loi S, Rosa DD, Chia S, Wardley A, Ueno T, Rossari J, Eidtmann H, Armour A, Piccart-Gebhart M, Rimm DL, Baselga J, Pusztai L.

Ann Oncol. 2019 Jun 1;30(6):1018. doi: 10.1093/annonc/mdy530. No abstract available.

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