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Items: 1 to 50 of 650

1.

Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.

Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team, Marra MA, Hansen C, Shah SP, Aparicio S.

Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026.

PMID:
31730858
2.

Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.

Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger Y.

Am J Physiol Cell Physiol. 2019 Nov 6. doi: 10.1152/ajpcell.00410.2019. [Epub ahead of print]

PMID:
31693398
3.

Planning Mass Eradication of Helicobacter pylori Infection for Indigenous Taiwanese Peoples to Reduce Gastric Cancer.

Bair MJ, Chuang SL, Lei WY, Chen CL, Tian HW, Chiang TH, Su WW, Lin CC, Chung Lo YT, Jou YY, Wu CY, Chia SL, Wu MS, Chen HH, Chu CH, Lee YC, Wang YW.

J Gastroenterol Hepatol. 2019 Nov 1. doi: 10.1111/jgh.14898. [Epub ahead of print]

PMID:
31677184
4.

Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.

Delivoria DC, Chia S, Habchi J, Perni M, Matis I, Papaevgeniou N, Reczko M, Chondrogianni N, Dobson CM, Vendruscolo M, Skretas G.

Sci Adv. 2019 Oct 16;5(10):eaax5108. doi: 10.1126/sciadv.aax5108. eCollection 2019 Oct.

5.

Effects of High Anxiety Scores on Surgical and Overall Treatment Plan in Patients with Breast Cancer Treated with Neoadjuvant Therapy.

LeVasseur N, Li H, Cheung W, Myers P, Mckevitt E, Warburton R, Willemsma KA, Tan AD, Chia S, Simmons C.

Oncologist. 2019 Oct 15. pii: theoncologist.2019-0512. doi: 10.1634/theoncologist.2019-0512. [Epub ahead of print]

PMID:
31615949
6.

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer.

Mohamed Amin Z, Che Ani MA, Tan SW, Yeap SK, Alitheen NB, Syed Najmuddin SUF, Kalyanasundram J, Chan SC, Veerakumarasivam A, Chia SL, Yusoff K.

Sci Rep. 2019 Sep 30;9(1):13999. doi: 10.1038/s41598-019-50222-z.

7.

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy.

Ruggeri FS, Šneideris T, Chia S, Vendruscolo M, Knowles TPJ.

J Vis Exp. 2019 Sep 12;(151). doi: 10.3791/60108.

PMID:
31566623
8.

An efficient and rapid method to extract and purify protein - Liquid Triphasic Flotation system.

Chia SR, Mak KY, Khaw YJ, Suhaidi N, Chew KW, Show PL.

Bioresour Technol. 2019 Dec;294:122158. doi: 10.1016/j.biortech.2019.122158. Epub 2019 Sep 17.

PMID:
31550634
9.

Effect of Dietary Replacement of Fishmeal by Insect Meal on Growth Performance, Blood Profiles and Economics of Growing Pigs in Kenya.

Chia SY, Tanga CM, Osuga IM, Alaru AO, Mwangi DM, Githinji M, Subramanian S, Fiaboe KKM, Ekesi S, van Loon JJA, Dicke M.

Animals (Basel). 2019 Sep 20;9(10). pii: E705. doi: 10.3390/ani9100705.

10.

Virotherapy: Current Trends and Future Prospects for Treatment of Colon and Rectal Malignancies.

Lee CL, Veeramani S, Molouki A, Lim SHE, Thomas W, Chia SL, Yusoff K.

Cancer Invest. 2019;37(8):393-414. doi: 10.1080/07357907.2019.1660887. Epub 2019 Sep 10. Review.

PMID:
31502477
11.

Association between serum heavy metals and prostate cancer risk - A multiple metal analysis.

Lim JT, Tan YQ, Valeri L, Lee J, Geok PP, Chia SE, Ong CN, Seow WJ.

Environ Int. 2019 Nov;132:105109. doi: 10.1016/j.envint.2019.105109. Epub 2019 Sep 3.

12.

A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229).

Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L.

Oncologist. 2019 Nov;24(11):1439-1445. doi: 10.1634/theoncologist.2019-0321. Epub 2019 Aug 16.

PMID:
31420468
13.

Recent Developments of Reverse Micellar Techniques for Lysozyme, Bovine Serum Albumin, and Bromelain Extraction.

Chia SR, Tang MSY, Chow YH, Ooi CW, Rambabu K, Zhu L, Show PL.

Mol Biotechnol. 2019 Oct;61(10):715-724. doi: 10.1007/s12033-019-00200-7. Review.

PMID:
31350687
14.

Concomitant pediatric abdominal and pulmonary tuberculosis.

Kuo HC, Chen SC, Lin HK, Chia ST, Leung JH.

Pediatr Neonatol. 2019 Jun 28. pii: S1875-9572(19)30127-5. doi: 10.1016/j.pedneo.2019.06.006. [Epub ahead of print] No abstract available.

15.

Efficacy of Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in ER-positive Breast Cancer: Results From a Prospective Institutional Database.

LeVasseur N, Willemsma KA, Li H, Gondara L, Yip WC, Illmann C, Chia SK, Simmons C.

Clin Breast Cancer. 2019 Jun 11. pii: S1526-8209(19)30033-3. doi: 10.1016/j.clbc.2019.05.020. [Epub ahead of print]

PMID:
31279611
16.

Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications.

Chia SR, Chew KW, Show PL, Xia A, Ho SH, Lim JW.

Bioresour Technol. 2019 Oct;289:121727. doi: 10.1016/j.biortech.2019.121727. Epub 2019 Jun 29.

PMID:
31279318
17.

Functional outcome and quality of life in patients with hip fracture after total knee arthroplasty.

Koh DTS, Chen JY, Yew AKS, Chong HC, Hao Y, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019852338. doi: 10.1177/2309499019852338.

PMID:
31204571
18.

Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?

LeVasseur N, Chia S.

Br J Cancer. 2019 Jul;121(1):1-2. doi: 10.1038/s41416-019-0484-8. Epub 2019 Jun 7.

PMID:
31171836
19.

Development and Validation of a Self-Assessment Tool for an Integrative Model of Health Promotion in Hospitals: Taiwan's Experience.

Wang YW, Chia SL, Chou CM, Chen MS, Pelikan JM, Chu C, Wang MH, Lee CB.

Int J Environ Res Public Health. 2019 Jun 1;16(11). pii: E1953. doi: 10.3390/ijerph16111953.

20.

Liquid biphasic flotation for the purification of C-phycocyanin from Spirulina platensis microalga.

Chew KW, Chia SR, Krishnamoorthy R, Tao Y, Chu DT, Show PL.

Bioresour Technol. 2019 Sep;288:121519. doi: 10.1016/j.biortech.2019.121519. Epub 2019 May 20.

PMID:
31128541
21.

Clinical outcomes and patient satisfaction following revision of failed unicompartmental knee arthroplasty to total knee arthroplasty are as good as a primary total knee arthroplasty.

Lim JBT, Pang HN, Tay KJD, Chia SL, Lo NN, Yeo SJ.

Knee. 2019 Aug;26(4):847-852. doi: 10.1016/j.knee.2019.04.016. Epub 2019 May 18.

PMID:
31113700
22.

Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor-positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT).

McCartney A, Biagioni C, Schiavon G, Bergqvist M, Mattsson K, Migliaccio I, Benelli M, Romagnoli D, Bonechi M, Boccalini G, Pestrin M, Galardi F, De Luca F, Biganzoli L, Piccart M, Gradishar WJ, Chia S, Di Leo A, Malorni L.

Eur J Cancer. 2019 Jun;114:55-66. doi: 10.1016/j.ejca.2019.04.002. Epub 2019 May 3.

PMID:
31059974
23.

The Singapore Heart Failure Risk Score: Prediction of Survival in Southeast Asian Patients.

Yap J, Chia SY, Lim FY, Allen JC, Teo L, Sim D, Go YY, Jaufeerally FR, Seow M, Kwok B, Liew R, Lam CS, Ching CK.

Ann Acad Med Singapore. 2019 Mar;48(3):86-94.

24.

Establishing an allied health professional delivered selective laser trabeculoplasty service in Scotland.

Chadwick O, Chia SN, Rotchford A.

Ophthalmic Physiol Opt. 2019 May;39(3):216-223. doi: 10.1111/opo.12611.

PMID:
30994202
25.

Current Landscape of Immunotherapy in Breast Cancer: A Review.

Adams S, Gatti-Mays ME, Kalinsky K, Korde LA, Sharon E, Amiri-Kordestani L, Bear H, McArthur HL, Frank E, Perlmutter J, Page DB, Vincent B, Hayes JF, Gulley JL, Litton JK, Hortobagyi GN, Chia S, Krop I, White J, Sparano J, Disis ML, Mittendorf EA.

JAMA Oncol. 2019 Apr 11. doi: 10.1001/jamaoncol.2018.7147. [Epub ahead of print]

PMID:
30973611
26.

PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial.

Chia SKL, Martin M, Holmes FA, Ejlertsen B, Delaloge S, Moy B, Iwata H, von Minckwitz G, Mansi J, Barrios CH, Gnant M, Tomašević Z, Denduluri N, Šeparović R, Kim SB, Jakobsen EH, Harvey V, Robert N, Smith J 2nd, Harker G, Zhang B, Eli LD, Ye Y, Lalani AS, Buyse M, Chan A.

Breast Cancer Res. 2019 Mar 11;21(1):39. doi: 10.1186/s13058-019-1115-2.

27.

Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III Trial.

Rothé F, Silva MJ, Venet D, Campbell C, Bradburry I, Rouas G, de Azambuja E, Maetens M, Fumagalli D, Rodrik-Outmezguine V, Di Cosimo S, Rosa D, Chia S, Wardley A, Ueno T, Janni W, Huober J, Baselga J, Piccart M, Loi S, Sotiriou C, Dawson SJ, Ignatiadis M.

Clin Cancer Res. 2019 Jun 15;25(12):3581-3588. doi: 10.1158/1078-0432.CCR-18-2521. Epub 2019 Mar 12.

PMID:
30862692
28.

Prediction of Survival in Asian Patients Hospitalized With Heart Failure: Validation of the OPTIMIZE-HF Risk Score.

Yap J, Lim FY, Chia SY, Allen JC Jr, Jaufeerally FR, Macdonald MR, Chai P, Loh SY, Lim P, Zaw MWW, Teo L, Sim D, Lam CSP.

J Card Fail. 2019 Jul;25(7):571-575. doi: 10.1016/j.cardfail.2019.02.016. Epub 2019 Feb 26.

PMID:
30822512
29.

Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.

Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW.

Antioxid Redox Signal. 2019 Nov 10;31(14):1070-1091. doi: 10.1089/ars.2019.7752. Epub 2019 Apr 5.

PMID:
30799628
30.

The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: A systematic review and network meta-analysis.

Xu S, Chen JY, Zheng Q, Lo NN, Chia SL, Tay KJD, Pang HN, Shi L, Chan ESY, Yeo SJ.

Thromb Res. 2019 Apr;176:61-66. doi: 10.1016/j.thromres.2019.02.006. Epub 2019 Feb 11.

PMID:
30776688
31.

The influence of obesity on clinical outcomes of fixed-bearing unicompartmental knee arthroplasty: a ten-year follow-up study.

Xu S, Lim WJ, Chen JY, Lo NN, Chia SL, Tay DKJ, Hao Y, Yeo SJ.

Bone Joint J. 2019 Feb;101-B(2):213-220. doi: 10.1302/0301-620X.101B2.BJJ-2018-0969.R2.

PMID:
30700121
32.

Effects of neratinib on health-related quality of life in women with HER2-positive early-stage breast cancer: longitudinal analyses from the randomized phase III ExteNET trial.

Delaloge S, Cella D, Ye Y, Buyse M, Chan A, Barrios CH, Holmes FA, Mansi J, Iwata H, Ejlertsen B, Moy B, Chia SKL, Gnant M, Smichkoska S, Ciceniene A, Martinez N, Filipović S, Ben-Baruch NE, Joy AA, Langkjer ST, Senecal F, de Boer RH, Moran S, Yao B, Bryce R, Auerbach A, Fallowfield L, Martin M.

Ann Oncol. 2019 Apr 1;30(4):567-574. doi: 10.1093/annonc/mdz016.

PMID:
30689703
33.

Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial.

Haldar S, Pakkiri LS, Lim J, Chia SC, Ponnalagu S, Drum CL, Henry CJ.

Front Physiol. 2019 Jan 9;9:1899. doi: 10.3389/fphys.2018.01899. eCollection 2018.

34.

Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.

Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM.

Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5.

35.

Slide-free imaging of hematoxylin-eosin stained whole-mount tissues using combined third-harmonic generation and three-photon fluorescence microscopy.

Sun CK, Kao CT, Wei ML, Chia SH, Kärtner FX, Ivanov A, Liao YH.

J Biophotonics. 2019 May;12(5):e201800341. doi: 10.1002/jbio.201800341. Epub 2019 Feb 27.

PMID:
30636033
36.

Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.

Ahn M, Lee BI, Chia S, Habchi J, Kumita JR, Vendruscolo M, Dobson CM, Park CB.

Chem Commun (Camb). 2019 Jan 25;55(8):1152-1155. doi: 10.1039/c8cc09288e. Epub 2019 Jan 11.

PMID:
30632567
37.

Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial.

Shi W, Jiang T, Nuciforo P, Hatzis C, Holmes E, Harbeck N, Sotiriou C, Peña L, Loi S, Rosa DD, Chia S, Wardley A, Ueno T, Rossari J, Eidtmann H, Armour A, Piccart-Gebhart M, Rimm DL, Baselga J, Pusztai L.

Ann Oncol. 2019 Jan 9. doi: 10.1093/annonc/mdy530. [Epub ahead of print] No abstract available.

38.

Effects of waste stream combinations from brewing industry on performance of Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae).

Chia SY, Tanga CM, Osuga IM, Mohamed SA, Khamis FM, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PeerJ. 2018 Nov 28;6:e5885. doi: 10.7717/peerj.5885. eCollection 2018.

39.

Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial.

Mamounas EP, Bandos H, Lembersky BC, Jeong JH, Geyer CE Jr, Rastogi P, Fehrenbacher L, Graham ML, Chia SK, Brufsky AM, Walshe JM, Soori GS, Dakhil SR, Seay TE, Wade JL 3rd, McCarron EC, Paik S, Swain SM, Wickerham DL, Wolmark N.

Lancet Oncol. 2019 Jan;20(1):88-99. doi: 10.1016/S1470-2045(18)30621-1. Epub 2018 Nov 30. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.

PMID:
30509771
40.

Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ Jr, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R; ADHERE registry investigators.

Eur Respir J. 2019 Jan 3;53(1). pii: 1801405. doi: 10.1183/13993003.01405-2018. Print 2019 Jan.

41.

Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.

Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R.

Nat Commun. 2018 Nov 22;9(1):4931. doi: 10.1038/s41467-018-07261-3.

42.

Correction to: Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes.

Teo JQ, Candra SR, Lee SJ, Chia SY, Leck H, Tan AL, Neo HP, Leow KW, Cai Y, Ee PLR, Lim TP, Lee W, Kwa AL.

Antimicrob Resist Infect Control. 2018 Nov 7;7:130. doi: 10.1186/s13756-018-0413-2. eCollection 2018.

43.

A systematic review of factors affecting medication adherence among patients with osteoporosis.

Yeam CT, Chia S, Tan HCC, Kwan YH, Fong W, Seng JJB.

Osteoporos Int. 2018 Dec;29(12):2623-2637. doi: 10.1007/s00198-018-4759-3. Epub 2018 Nov 12. Review.

PMID:
30417253
44.

Auto-flocculation through cultivation of Chlorella vulgaris in seafood wastewater discharge: Influence of culture conditions on microalgae growth and nutrient removal.

Nguyen TDP, Tran TNT, Le TVA, Nguyen Phan TX, Show PL, Chia SR.

J Biosci Bioeng. 2019 Apr;127(4):492-498. doi: 10.1016/j.jbiosc.2018.09.004. Epub 2018 Nov 8.

PMID:
30416001
45.

Threshold temperatures and thermal requirements of black soldier fly Hermetia illucens: Implications for mass production.

Chia SY, Tanga CM, Khamis FM, Mohamed SA, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PLoS One. 2018 Nov 1;13(11):e0206097. doi: 10.1371/journal.pone.0206097. eCollection 2018.

46.

TIM-3 expression in breast cancer.

Burugu S, Gao D, Leung S, Chia SK, Nielsen TO.

Oncoimmunology. 2018 Aug 23;7(11):e1502128. doi: 10.1080/2162402X.2018.1502128. eCollection 2018.

47.

Mortality outcome and predictive risk factors for death in patients with heart failure and reduced ejection fraction who declined implantable cardioverter defibrillator implantation in Singapore.

Khoo CY, Allen JC, Chia SY, Chan LL, Lim CP, Sim D, Ching CK.

J Arrhythm. 2018 Aug 18;34(5):536-540. doi: 10.1002/joa3.12106. eCollection 2018 Oct.

48.

Pre-existing patellofemoral disease does not affect 10-year survivorship in fixed bearing unicompartmental knee arthroplasty.

Lim JW, Chen JY, Chong HC, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):2030-2036. doi: 10.1007/s00167-018-5169-y. Epub 2018 Oct 4.

PMID:
30288570
49.

[Chronic Disease Prevention: Present and Future].

Chia SL, Chou WC, Chen RC.

Hu Li Za Zhi. 2018 Oct;65(5):13-19. doi: 10.6224/JN.201810_65(5).03. Chinese.

PMID:
30276768
50.

SAR by kinetics for drug discovery in protein misfolding diseases.

Chia S, Habchi J, Michaels TCT, Cohen SIA, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10245-10250. doi: 10.1073/pnas.1807884115. Epub 2018 Sep 26.

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