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Virotherapy: Current Trends and Future Prospects for Treatment of Colon and Rectal Malignancies.

Lee CL, Veeramani S, Molouki A, Lim SHE, Thomas W, Chia SL, Yusoff K.

Cancer Invest. 2019 Sep 10:1-22. doi: 10.1080/07357907.2019.1660887. [Epub ahead of print]


Association between serum heavy metals and prostate cancer risk - A multiple metal analysis.

Lim JT, Tan YQ, Valeri L, Lee J, Geok PP, Chia SE, Ong CN, Seow WJ.

Environ Int. 2019 Sep 3;132:105109. doi: 10.1016/j.envint.2019.105109. [Epub ahead of print]


A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229).

Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L.

Oncologist. 2019 Aug 16. pii: theoncologist.2019-0321. doi: 10.1634/theoncologist.2019-0321. [Epub ahead of print]


Recent Developments of Reverse Micellar Techniques for Lysozyme, Bovine Serum Albumin, and Bromelain Extraction.

Chia SR, Tang MSY, Chow YH, Ooi CW, Rambabu K, Zhu L, Show PL.

Mol Biotechnol. 2019 Oct;61(10):715-724. doi: 10.1007/s12033-019-00200-7. Review.


Concomitant pediatric abdominal and pulmonary tuberculosis.

Kuo HC, Chen SC, Lin HK, Chia ST, Leung JH.

Pediatr Neonatol. 2019 Jun 28. pii: S1875-9572(19)30127-5. doi: 10.1016/j.pedneo.2019.06.006. [Epub ahead of print] No abstract available.


Efficacy of Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in ER-positive Breast Cancer: Results From a Prospective Institutional Database.

LeVasseur N, Willemsma KA, Li H, Gondara L, Yip WC, Illmann C, Chia SK, Simmons C.

Clin Breast Cancer. 2019 Jun 11. pii: S1526-8209(19)30033-3. doi: 10.1016/j.clbc.2019.05.020. [Epub ahead of print]


Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications.

Chia SR, Chew KW, Show PL, Xia A, Ho SH, Lim JW.

Bioresour Technol. 2019 Oct;289:121727. doi: 10.1016/j.biortech.2019.121727. Epub 2019 Jun 29.


Functional outcome and quality of life in patients with hip fracture after total knee arthroplasty.

Koh DTS, Chen JY, Yew AKS, Chong HC, Hao Y, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019852338. doi: 10.1177/2309499019852338.


Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?

LeVasseur N, Chia S.

Br J Cancer. 2019 Jul;121(1):1-2. doi: 10.1038/s41416-019-0484-8. Epub 2019 Jun 7.


Development and Validation of a Self-Assessment Tool for an Integrative Model of Health Promotion in Hospitals: Taiwan's Experience.

Wang YW, Chia SL, Chou CM, Chen MS, Pelikan JM, Chu C, Wang MH, Lee CB.

Int J Environ Res Public Health. 2019 Jun 1;16(11). pii: E1953. doi: 10.3390/ijerph16111953.


Liquid biphasic flotation for the purification of C-phycocyanin from Spirulina platensis microalga.

Chew KW, Chia SR, Krishnamoorthy R, Tao Y, Chu DT, Show PL.

Bioresour Technol. 2019 Sep;288:121519. doi: 10.1016/j.biortech.2019.121519. Epub 2019 May 20.


Clinical outcomes and patient satisfaction following revision of failed unicompartmental knee arthroplasty to total knee arthroplasty are as good as a primary total knee arthroplasty.

Lim JBT, Pang HN, Tay KJD, Chia SL, Lo NN, Yeo SJ.

Knee. 2019 Aug;26(4):847-852. doi: 10.1016/j.knee.2019.04.016. Epub 2019 May 18.


Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor-positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT).

McCartney A, Biagioni C, Schiavon G, Bergqvist M, Mattsson K, Migliaccio I, Benelli M, Romagnoli D, Bonechi M, Boccalini G, Pestrin M, Galardi F, De Luca F, Biganzoli L, Piccart M, Gradishar WJ, Chia S, Di Leo A, Malorni L.

Eur J Cancer. 2019 Jun;114:55-66. doi: 10.1016/j.ejca.2019.04.002. Epub 2019 May 3.


The Singapore Heart Failure Risk Score: Prediction of Survival in Southeast Asian Patients.

Yap J, Chia SY, Lim FY, Allen JC, Teo L, Sim D, Go YY, Jaufeerally FR, Seow M, Kwok B, Liew R, Lam CS, Ching CK.

Ann Acad Med Singapore. 2019 Mar;48(3):86-94.


Establishing an allied health professional delivered selective laser trabeculoplasty service in Scotland.

Chadwick O, Chia SN, Rotchford A.

Ophthalmic Physiol Opt. 2019 May;39(3):216-223. doi: 10.1111/opo.12611.


Current Landscape of Immunotherapy in Breast Cancer: A Review.

Adams S, Gatti-Mays ME, Kalinsky K, Korde LA, Sharon E, Amiri-Kordestani L, Bear H, McArthur HL, Frank E, Perlmutter J, Page DB, Vincent B, Hayes JF, Gulley JL, Litton JK, Hortobagyi GN, Chia S, Krop I, White J, Sparano J, Disis ML, Mittendorf EA.

JAMA Oncol. 2019 Apr 11. doi: 10.1001/jamaoncol.2018.7147. [Epub ahead of print]


PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial.

Chia SKL, Martin M, Holmes FA, Ejlertsen B, Delaloge S, Moy B, Iwata H, von Minckwitz G, Mansi J, Barrios CH, Gnant M, Tomašević Z, Denduluri N, Šeparović R, Kim SB, Jakobsen EH, Harvey V, Robert N, Smith J 2nd, Harker G, Zhang B, Eli LD, Ye Y, Lalani AS, Buyse M, Chan A.

Breast Cancer Res. 2019 Mar 11;21(1):39. doi: 10.1186/s13058-019-1115-2.


Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III Trial.

Rothé F, Silva MJ, Venet D, Campbell C, Bradburry I, Rouas G, de Azambuja E, Maetens M, Fumagalli D, Rodrik-Outmezguine V, Di Cosimo S, Rosa D, Chia S, Wardley A, Ueno T, Janni W, Huober J, Baselga J, Piccart M, Loi S, Sotiriou C, Dawson SJ, Ignatiadis M.

Clin Cancer Res. 2019 Jun 15;25(12):3581-3588. doi: 10.1158/1078-0432.CCR-18-2521. Epub 2019 Mar 12.


Prediction of Survival in Asian Patients Hospitalized With Heart Failure: Validation of the OPTIMIZE-HF Risk Score.

Yap J, Lim FY, Chia SY, Allen JC Jr, Jaufeerally FR, Macdonald MR, Chai P, Loh SY, Lim P, Zaw MWW, Teo L, Sim D, Lam CSP.

J Card Fail. 2019 Jul;25(7):571-575. doi: 10.1016/j.cardfail.2019.02.016. Epub 2019 Feb 26.


Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.

Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW.

Antioxid Redox Signal. 2019 Apr 5. doi: 10.1089/ars.2019.7752. [Epub ahead of print]


The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: A systematic review and network meta-analysis.

Xu S, Chen JY, Zheng Q, Lo NN, Chia SL, Tay KJD, Pang HN, Shi L, Chan ESY, Yeo SJ.

Thromb Res. 2019 Apr;176:61-66. doi: 10.1016/j.thromres.2019.02.006. Epub 2019 Feb 11.


The influence of obesity on clinical outcomes of fixed-bearing unicompartmental knee arthroplasty: a ten-year follow-up study.

Xu S, Lim WJ, Chen JY, Lo NN, Chia SL, Tay DKJ, Hao Y, Yeo SJ.

Bone Joint J. 2019 Feb;101-B(2):213-220. doi: 10.1302/0301-620X.101B2.BJJ-2018-0969.R2.


Effects of neratinib on health-related quality of life in women with HER2-positive early-stage breast cancer: longitudinal analyses from the randomized phase III ExteNET trial.

Delaloge S, Cella D, Ye Y, Buyse M, Chan A, Barrios CH, Holmes FA, Mansi J, Iwata H, Ejlertsen B, Moy B, Chia SKL, Gnant M, Smichkoska S, Ciceniene A, Martinez N, Filipović S, Ben-Baruch NE, Joy AA, Langkjer ST, Senecal F, de Boer RH, Moran S, Yao B, Bryce R, Auerbach A, Fallowfield L, Martin M.

Ann Oncol. 2019 Apr 1;30(4):567-574. doi: 10.1093/annonc/mdz016.


Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial.

Haldar S, Pakkiri LS, Lim J, Chia SC, Ponnalagu S, Drum CL, Henry CJ.

Front Physiol. 2019 Jan 9;9:1899. doi: 10.3389/fphys.2018.01899. eCollection 2018.


Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.

Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM.

Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5.


Slide-free imaging of hematoxylin-eosin stained whole-mount tissues using combined third-harmonic generation and three-photon fluorescence microscopy.

Sun CK, Kao CT, Wei ML, Chia SH, Kärtner FX, Ivanov A, Liao YH.

J Biophotonics. 2019 May;12(5):e201800341. doi: 10.1002/jbio.201800341. Epub 2019 Feb 27.


Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.

Ahn M, Lee BI, Chia S, Habchi J, Kumita JR, Vendruscolo M, Dobson CM, Park CB.

Chem Commun (Camb). 2019 Jan 25;55(8):1152-1155. doi: 10.1039/c8cc09288e. Epub 2019 Jan 11.


Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial.

Shi W, Jiang T, Nuciforo P, Hatzis C, Holmes E, Harbeck N, Sotiriou C, Peña L, Loi S, Rosa DD, Chia S, Wardley A, Ueno T, Rossari J, Eidtmann H, Armour A, Piccart-Gebhart M, Rimm DL, Baselga J, Pusztai L.

Ann Oncol. 2019 Jan 9. doi: 10.1093/annonc/mdy530. [Epub ahead of print] No abstract available.


Effects of waste stream combinations from brewing industry on performance of Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae).

Chia SY, Tanga CM, Osuga IM, Mohamed SA, Khamis FM, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PeerJ. 2018 Nov 28;6:e5885. doi: 10.7717/peerj.5885. eCollection 2018.


Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial.

Mamounas EP, Bandos H, Lembersky BC, Jeong JH, Geyer CE Jr, Rastogi P, Fehrenbacher L, Graham ML, Chia SK, Brufsky AM, Walshe JM, Soori GS, Dakhil SR, Seay TE, Wade JL 3rd, McCarron EC, Paik S, Swain SM, Wickerham DL, Wolmark N.

Lancet Oncol. 2019 Jan;20(1):88-99. doi: 10.1016/S1470-2045(18)30621-1. Epub 2018 Nov 30. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.


Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ Jr, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R; ADHERE registry investigators.

Eur Respir J. 2019 Jan 3;53(1). pii: 1801405. doi: 10.1183/13993003.01405-2018. Print 2019 Jan.


Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.

Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R.

Nat Commun. 2018 Nov 22;9(1):4931. doi: 10.1038/s41467-018-07261-3.


Correction to: Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes.

Teo JQ, Candra SR, Lee SJ, Chia SY, Leck H, Tan AL, Neo HP, Leow KW, Cai Y, Ee PLR, Lim TP, Lee W, Kwa AL.

Antimicrob Resist Infect Control. 2018 Nov 7;7:130. doi: 10.1186/s13756-018-0413-2. eCollection 2018.


A systematic review of factors affecting medication adherence among patients with osteoporosis.

Yeam CT, Chia S, Tan HCC, Kwan YH, Fong W, Seng JJB.

Osteoporos Int. 2018 Dec;29(12):2623-2637. doi: 10.1007/s00198-018-4759-3. Epub 2018 Nov 12. Review.


Auto-flocculation through cultivation of Chlorella vulgaris in seafood wastewater discharge: Influence of culture conditions on microalgae growth and nutrient removal.

Nguyen TDP, Tran TNT, Le TVA, Nguyen Phan TX, Show PL, Chia SR.

J Biosci Bioeng. 2019 Apr;127(4):492-498. doi: 10.1016/j.jbiosc.2018.09.004. Epub 2018 Nov 8.


Threshold temperatures and thermal requirements of black soldier fly Hermetia illucens: Implications for mass production.

Chia SY, Tanga CM, Khamis FM, Mohamed SA, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PLoS One. 2018 Nov 1;13(11):e0206097. doi: 10.1371/journal.pone.0206097. eCollection 2018.


TIM-3 expression in breast cancer.

Burugu S, Gao D, Leung S, Chia SK, Nielsen TO.

Oncoimmunology. 2018 Aug 23;7(11):e1502128. doi: 10.1080/2162402X.2018.1502128. eCollection 2018.


Mortality outcome and predictive risk factors for death in patients with heart failure and reduced ejection fraction who declined implantable cardioverter defibrillator implantation in Singapore.

Khoo CY, Allen JC, Chia SY, Chan LL, Lim CP, Sim D, Ching CK.

J Arrhythm. 2018 Aug 18;34(5):536-540. doi: 10.1002/joa3.12106. eCollection 2018 Oct.


Pre-existing patellofemoral disease does not affect 10-year survivorship in fixed bearing unicompartmental knee arthroplasty.

Lim JW, Chen JY, Chong HC, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):2030-2036. doi: 10.1007/s00167-018-5169-y. Epub 2018 Oct 4.


[Chronic Disease Prevention: Present and Future].

Chia SL, Chou WC, Chen RC.

Hu Li Za Zhi. 2018 Oct;65(5):13-19. doi: 10.6224/JN.201810_65(5).03. Chinese.


SAR by kinetics for drug discovery in protein misfolding diseases.

Chia S, Habchi J, Michaels TCT, Cohen SIA, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10245-10250. doi: 10.1073/pnas.1807884115. Epub 2018 Sep 26.


Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.

Ruggeri FS, Charmet J, Kartanas T, Peter Q, Chia S, Habchi J, Dobson CM, Vendruscolo M, Knowles TPJ.

Nat Commun. 2018 Sep 24;9(1):3890. doi: 10.1038/s41467-018-06345-4.


Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2.

Campone M, Im SA, Iwata H, Clemons M, Ito Y, Awada A, Chia S, Jagiełło-Gruszfeld A, Pistilli B, Tseng LM, Hurvitz S, Masuda N, Cortés J, De Laurentiis M, Arteaga CL, Jiang Z, Jonat W, Le Mouhaër S, Sankaran B, Bourdeau L, El-Hashimy M, Sellami D, Baselga J.

Eur J Cancer. 2018 Nov;103:147-154. doi: 10.1016/j.ejca.2018.08.002. Epub 2018 Sep 18.


Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes.

Chia SZ, Lai YW, Yagoub D, Lev S, Hamey JJ, Pang CNI, Desmarini D, Chen Z, Djordjevic JT, Erce MA, Hart-Smith G, Wilkins MR.

Mol Cell Proteomics. 2018 Dec;17(12):2462-2479. doi: 10.1074/mcp.RA117.000214. Epub 2018 Sep 11.


Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.

Cancer Gene Ther. 2019 Mar;26(3-4):59-73. doi: 10.1038/s41417-018-0042-1. Epub 2018 Sep 4.


Near-White Light Emission from Lead(II) Metal-Organic Frameworks.

Peedikakkal AMP, Quah HS, Chia S, Jalilov AS, Shaikh AR, Al-Mohsin HA, Yadava K, Ji W, Vittal JJ.

Inorg Chem. 2018 Sep 17;57(18):11341-11348. doi: 10.1021/acs.inorgchem.8b00637. Epub 2018 Aug 29.


Asymmetrical meta-methoxylated diarylpentanoids: Rational design, synthesis and anti-cancer evaluation in-vitro.

Leong SW, Chia SL, Abas F, Yusoff K.

Eur J Med Chem. 2018 Sep 5;157:716-728. doi: 10.1016/j.ejmech.2018.08.039. Epub 2018 Aug 16.


Dose-Dependent Increase in Unconjugated Cinnamic Acid Concentration in Plasma Following Acute Consumption of Polyphenol Rich Curry in the Polyspice Study.

Haldar S, Lee SH, Tan JJ, Chia SC, Henry CJ, Chan ECY.

Nutrients. 2018 Jul 20;10(7). pii: E934. doi: 10.3390/nu10070934.


Food waste compost as an organic nutrient source for the cultivation of Chlorella vulgaris.

Chew KW, Chia SR, Show PL, Ling TC, Arya SS, Chang JS.

Bioresour Technol. 2018 Nov;267:356-362. doi: 10.1016/j.biortech.2018.07.069. Epub 2018 Jul 20.


Understanding adjuvant endocrine therapy persistence in breast Cancer survivors.

Lambert LK, Balneaves LG, Howard AF, Chia SK, Gotay CC.

BMC Cancer. 2018 Jul 11;18(1):732. doi: 10.1186/s12885-018-4644-7.

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