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The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: A systemic review and network meta-analysis.

Xu S, Chen JY, Zheng Q, Lo NN, Chia SL, Tay KJD, Pang HN, Shi L, Chan ESY, Yeo SJ.

Thromb Res. 2019 Feb 11;176:61-66. doi: 10.1016/j.thromres.2019.02.006. [Epub ahead of print]


The influence of obesity on clinical outcomes of fixed-bearing unicompartmental knee arthroplasty.

Xu S, Lim WJ, Chen JY, Lo NN, Chia SL, Tay DKJ, Hao Y, Yeo SJ.

Bone Joint J. 2019 Feb;101-B(2):213-220. doi: 10.1302/0301-620X.101B2.BJJ-2018-0969.R2.


Effects of Neratinib on Health-Related Quality-of-Life in Women with HER2-Positive Early-Stage Breast Cancer: Longitudinal Analyses from the Randomized Phase III ExteNET Trial.

Delaloge S, Cella D, Ye Y, Buyse M, Chan A, Barrios CH, Holmes FA, Mansi J, Iwata H, Ejlertsen B, Moy B, Chia SKL, Gnant M, Smichkoska S, Ciceniene A, Martinez N, Filipovic S, Ben-Baruch NE, Joy AA, Langkjer ST, Senecal F, de Boer RH, Moran S, Yao B, Bryce R, Auerbach A, Fallowfield L, Martin M.

Ann Oncol. 2019 Jan 23. doi: 10.1093/annonc/mdz016. [Epub ahead of print]


Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial.

Haldar S, Pakkiri LS, Lim J, Chia SC, Ponnalagu S, Drum CL, Henry CJ.

Front Physiol. 2019 Jan 9;9:1899. doi: 10.3389/fphys.2018.01899. eCollection 2018.


Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.

Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM.

Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5.


Slide-free imaging of hematoxylin-eosin stained whole-mount tissues using combined third-harmonic generation and three-photon fluorescence microscopy.

Sun CK, Kao CT, Wei ML, Chia SH, Kärtner FX, Ivanov A, Liao YH.

J Biophotonics. 2019 Jan 12. doi: 10.1002/jbio.201800341. [Epub ahead of print]


Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.

Ahn M, Lee BI, Chia S, Habchi J, Kumita JR, Vendruscolo M, Dobson CM, Park CB.

Chem Commun (Camb). 2019 Jan 25;55(8):1152-1155. doi: 10.1039/c8cc09288e. Epub 2019 Jan 11.


Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial.

Shi W, Jiang T, Nuciforo P, Hatzis C, Holmes E, Harbeck N, Sotiriou C, Peña L, Loi S, Rosa DD, Chia S, Wardley A, Ueno T, Rossari J, Eidtmann H, Armour A, Piccart-Gebhart M, Rimm DL, Baselga J, Pusztai L.

Ann Oncol. 2019 Jan 9. doi: 10.1093/annonc/mdy530. [Epub ahead of print] No abstract available.


Effects of waste stream combinations from brewing industry on performance of Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae).

Chia SY, Tanga CM, Osuga IM, Mohamed SA, Khamis FM, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PeerJ. 2018 Nov 28;6:e5885. doi: 10.7717/peerj.5885. eCollection 2018.


Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial.

Mamounas EP, Bandos H, Lembersky BC, Jeong JH, Geyer CE Jr, Rastogi P, Fehrenbacher L, Graham ML, Chia SK, Brufsky AM, Walshe JM, Soori GS, Dakhil SR, Seay TE, Wade JL 3rd, McCarron EC, Paik S, Swain SM, Wickerham DL, Wolmark N.

Lancet Oncol. 2019 Jan;20(1):88-99. doi: 10.1016/S1470-2045(18)30621-1. Epub 2018 Nov 30. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.


Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ Jr, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R; ADHERE registry investigators.

Eur Respir J. 2019 Jan 3;53(1). pii: 1801405. doi: 10.1183/13993003.01405-2018. Print 2019 Jan.


Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.

Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R.

Nat Commun. 2018 Nov 22;9(1):4931. doi: 10.1038/s41467-018-07261-3.


Correction to: Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes.

Teo JQ, Candra SR, Lee SJ, Chia SY, Leck H, Tan AL, Neo HP, Leow KW, Cai Y, Ee PLR, Lim TP, Lee W, Kwa AL.

Antimicrob Resist Infect Control. 2018 Nov 7;7:130. doi: 10.1186/s13756-018-0413-2. eCollection 2018.


A systematic review of factors affecting medication adherence among patients with osteoporosis.

Yeam CT, Chia S, Tan HCC, Kwan YH, Fong W, Seng JJB.

Osteoporos Int. 2018 Dec;29(12):2623-2637. doi: 10.1007/s00198-018-4759-3. Epub 2018 Nov 12. Review.


Auto-flocculation through cultivation of Chlorella vulgaris in seafood wastewater discharge: Influence of culture conditions on microalgae growth and nutrient removal.

Nguyen TDP, Tran TNT, Le TVA, Nguyen Phan TX, Show PL, Chia SR.

J Biosci Bioeng. 2018 Nov 8. pii: S1389-1723(18)30686-8. doi: 10.1016/j.jbiosc.2018.09.004. [Epub ahead of print]


Threshold temperatures and thermal requirements of black soldier fly Hermetia illucens: Implications for mass production.

Chia SY, Tanga CM, Khamis FM, Mohamed SA, Salifu D, Sevgan S, Fiaboe KKM, Niassy S, van Loon JJA, Dicke M, Ekesi S.

PLoS One. 2018 Nov 1;13(11):e0206097. doi: 10.1371/journal.pone.0206097. eCollection 2018.


TIM-3 expression in breast cancer.

Burugu S, Gao D, Leung S, Chia SK, Nielsen TO.

Oncoimmunology. 2018 Aug 23;7(11):e1502128. doi: 10.1080/2162402X.2018.1502128. eCollection 2018.


Mortality outcome and predictive risk factors for death in patients with heart failure and reduced ejection fraction who declined implantable cardioverter defibrillator implantation in Singapore.

Khoo CY, Allen JC, Chia SY, Chan LL, Lim CP, Sim D, Ching CK.

J Arrhythm. 2018 Aug 18;34(5):536-540. doi: 10.1002/joa3.12106. eCollection 2018 Oct.


Pre-existing patellofemoral disease does not affect 10-year survivorship in fixed bearing unicompartmental knee arthroplasty.

Lim JW, Chen JY, Chong HC, Pang HN, Tay DKJ, Chia SL, Lo NN, Yeo SJ.

Knee Surg Sports Traumatol Arthrosc. 2018 Oct 4. doi: 10.1007/s00167-018-5169-y. [Epub ahead of print]


[Chronic Disease Prevention: Present and Future].

Chia SL, Chou WC, Chen RC.

Hu Li Za Zhi. 2018 Oct;65(5):13-19. doi: 10.6224/JN.201810_65(5).03. Chinese.


SAR by kinetics for drug discovery in protein misfolding diseases.

Chia S, Habchi J, Michaels TCT, Cohen SIA, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10245-10250. doi: 10.1073/pnas.1807884115. Epub 2018 Sep 26.


Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.

Ruggeri FS, Charmet J, Kartanas T, Peter Q, Chia S, Habchi J, Dobson CM, Vendruscolo M, Knowles TPJ.

Nat Commun. 2018 Sep 24;9(1):3890. doi: 10.1038/s41467-018-06345-4.


Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2.

Campone M, Im SA, Iwata H, Clemons M, Ito Y, Awada A, Chia S, Jagiełło-Gruszfeld A, Pistilli B, Tseng LM, Hurvitz S, Masuda N, Cortés J, De Laurentiis M, Arteaga CL, Jiang Z, Jonat W, Le Mouhaër S, Sankaran B, Bourdeau L, El-Hashimy M, Sellami D, Baselga J.

Eur J Cancer. 2018 Nov;103:147-154. doi: 10.1016/j.ejca.2018.08.002. Epub 2018 Sep 18.


Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes.

Chia SZ, Lai YW, Yagoub D, Lev S, Hamey JJ, Pang CNI, Desmarini D, Chen Z, Djordjevic JT, Erce MA, Hart-Smith G, Wilkins MR.

Mol Cell Proteomics. 2018 Dec;17(12):2462-2479. doi: 10.1074/mcp.RA117.000214. Epub 2018 Sep 11.


Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.

Cancer Gene Ther. 2018 Sep 4. doi: 10.1038/s41417-018-0042-1. [Epub ahead of print]


Near-White Light Emission from Lead(II) Metal-Organic Frameworks.

Peedikakkal AMP, Quah HS, Chia S, Jalilov AS, Shaikh AR, Al-Mohsin HA, Yadava K, Ji W, Vittal JJ.

Inorg Chem. 2018 Sep 17;57(18):11341-11348. doi: 10.1021/acs.inorgchem.8b00637. Epub 2018 Aug 29.


Asymmetrical meta-methoxylated diarylpentanoids: Rational design, synthesis and anti-cancer evaluation in-vitro.

Leong SW, Chia SL, Abas F, Yusoff K.

Eur J Med Chem. 2018 Sep 5;157:716-728. doi: 10.1016/j.ejmech.2018.08.039. Epub 2018 Aug 16.


Dose-Dependent Increase in Unconjugated Cinnamic Acid Concentration in Plasma Following Acute Consumption of Polyphenol Rich Curry in the Polyspice Study.

Haldar S, Lee SH, Tan JJ, Chia SC, Henry CJ, Chan ECY.

Nutrients. 2018 Jul 20;10(7). pii: E934. doi: 10.3390/nu10070934.


Food waste compost as an organic nutrient source for the cultivation of Chlorella vulgaris.

Chew KW, Chia SR, Show PL, Ling TC, Arya SS, Chang JS.

Bioresour Technol. 2018 Nov;267:356-362. doi: 10.1016/j.biortech.2018.07.069. Epub 2018 Jul 20.


Understanding adjuvant endocrine therapy persistence in breast Cancer survivors.

Lambert LK, Balneaves LG, Howard AF, Chia SK, Gotay CC.

BMC Cancer. 2018 Jul 11;18(1):732. doi: 10.1186/s12885-018-4644-7.


Reducing protein oxidation reverses lung fibrosis.

Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW.

Nat Med. 2018 Aug;24(8):1128-1135. doi: 10.1038/s41591-018-0090-y. Epub 2018 Jul 9.


Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions.

Mannini B, Habchi J, Chia S, Ruggeri FS, Perni M, Knowles TPJ, Dobson CM, Vendruscolo M.

ACS Chem Neurosci. 2018 Aug 10. doi: 10.1021/acschemneuro.8b00141. [Epub ahead of print]


Cost Effectiveness of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Management of Colorectal Peritoneal Carcinomatosis.

Lee ZJ, Chia SL, Tan G, Soo KC, Teo CCM.

Ann Surg Oncol. 2018 Aug;25(8):2340-2346. doi: 10.1245/s10434-018-6508-4. Epub 2018 Jun 8.


Hormone receptor-positive, HER2-negative metastatic breast cancer: redrawing the lines.

Matutino A, Joy AA, Brezden-Masley C, Chia S, Verma S.

Curr Oncol. 2018 Jun;25(Suppl 1):S131-S141. doi: 10.3747/co.25.4000. Epub 2018 Jun 13. Review.


Clinical application and utility of genomic assays in early-stage breast cancer: key lessons learned to date.

Chia SKL.

Curr Oncol. 2018 Jun;25(Suppl 1):S125-S130. doi: 10.3747/co.25.3814. Epub 2018 Jun 13. Review.


Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: MONALEESA-3.

Slamon DJ, Neven P, Chia S, Fasching PA, De Laurentiis M, Im SA, Petrakova K, Bianchi GV, Esteva FJ, Martín M, Nusch A, Sonke GS, De la Cruz-Merino L, Beck JT, Pivot X, Vidam G, Wang Y, Rodriguez Lorenc K, Miller M, Taran T, Jerusalem G.

J Clin Oncol. 2018 Aug 20;36(24):2465-2472. doi: 10.1200/JCO.2018.78.9909. Epub 2018 Jun 3.


Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.

Habchi J, Chia S, Galvagnion C, Michaels TCT, Bellaiche MMJ, Ruggeri FS, Sanguanini M, Idini I, Kumita JR, Sparr E, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M.

Nat Chem. 2018 Jun;10(6):673-683. doi: 10.1038/s41557-018-0031-x. Epub 2018 May 7.


Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial.

Shi W, Jiang T, Nuciforo P, Hatzis C, Holmes E, Harbeck N, Sotiriou C, Peña L, Loi S, Rosa DD, Chia S, Wardley A, Ueno T, Rossari J, Eidtmann H, Armour A, Piccart-Gebhart M, Rimm DL, Baselga J, Pusztai L.

Ann Oncol. 2018 Oct 1;29(10):2152. doi: 10.1093/annonc/mdx805. No abstract available.


The influence of obesity on functional outcome and quality of life after total knee arthroplasty.

Xu S, Chen JY, Lo NN, Chia SL, Tay DKJ, Pang HN, Hao Y, Yeo SJ.

Bone Joint J. 2018 May 1;100-B(5):579-583. doi: 10.1302/0301-620X.100B5.BJJ-2017-1263.R1.


Sustainable approach in phlorotannin recovery from macroalgae.

Chia SR, Show PL, Phang SM, Ling TC, Ong HC.

J Biosci Bioeng. 2018 Aug;126(2):220-225. doi: 10.1016/j.jbiosc.2018.02.015. Epub 2018 Apr 16.


Newcastle disease virus strain AF2240 as an oncolytic virus: A review.

Kalyanasundram J, Hamid A, Yusoff K, Chia SL.

Acta Trop. 2018 Jul;183:126-133. doi: 10.1016/j.actatropica.2018.04.007. Epub 2018 Apr 4. Review.


De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis.

Ding C, Lim YC, Chia SY, Walet ACE, Xu S, Lo KA, Zhao Y, Zhu D, Shan Z, Chen Q, Leow MK, Xu D, Sun L.

Nat Commun. 2018 Apr 6;9(1):1329. doi: 10.1038/s41467-018-03754-3.


Effects of Two Doses of Curry Prepared with Mixed Spices on Postprandial Ghrelin and Subjective Appetite Responses-A Randomized Controlled Crossover Trial.

Haldar S, Lim J, Chia SC, Ponnalagu S, Henry CJ.

Foods. 2018 Mar 26;7(4). pii: E47. doi: 10.3390/foods7040047.


Upper Airway Stimulation for Obstructive Sleep Apnea: Results from the ADHERE Registry.

Boon M, Huntley C, Steffen A, Maurer JT, Sommer JU, Schwab R, Thaler E, Soose R, Chou C, Strollo P, Kezirian EJ, Chia S, Withrow K, Weidenbecher M, Strohl K, Doghramji K, Hofauer B, Heiser C; ADHERE Registry Investigators.

Otolaryngol Head Neck Surg. 2018 Aug;159(2):379-385. doi: 10.1177/0194599818764896. Epub 2018 Mar 20.


Oral water soluble contrast for malignant bowel obstruction.

Syrmis W, Richard R, Jenkins-Marsh S, Chia SC, Good P.

Cochrane Database Syst Rev. 2018 Mar 7;3:CD012014. doi: 10.1002/14651858.CD012014.pub2. Review.


Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation.

Michaels TCT, Šarić A, Habchi J, Chia S, Meisl G, Vendruscolo M, Dobson CM, Knowles TPJ.

Annu Rev Phys Chem. 2018 Apr 20;69:273-298. doi: 10.1146/annurev-physchem-050317-021322. Epub 2018 Feb 28. Review.


Comparison of hepatic and serum lipid signatures in hepatocellular carcinoma patients leads to the discovery of diagnostic and prognostic biomarkers.

Lu Y, Chen J, Huang C, Li N, Zou L, Chia SE, Chen S, Yu K, Ling Q, Cheng Q, Zhu M, Zhang W, Chen M, Ong CN.

Oncotarget. 2017 Dec 13;9(4):5032-5043. doi: 10.18632/oncotarget.23494. eCollection 2018 Jan 12.


Patient preferences for types of community-based cardiac rehabilitation programme.

Chia S, Wong XY, Toon ML, Seah Y, Yap AF, Lim C, Tay HY, Fong W, Low LL, Kwan YH.

Heart Asia. 2018 Jan 26;10(1):e010976. doi: 10.1136/heartasia-2017-010976. eCollection 2018.


Comparison of outcome measures from different pathways following total knee arthroplasty.

Chan HY, Sultana R, Yeo SJ, Chia SL, Pang HN, Lo NN.

Singapore Med J. 2018 Sep;59(9):476-486. doi: 10.11622/smedj.2018011. Epub 2018 Jan 26.


Analysis of Economic and Environmental Aspects of Microalgae Biorefinery for Biofuels Production: A Review.

Chia SR, Chew KW, Show PL, Yap YJ, Ong HC, Ling TC, Chang JS.

Biotechnol J. 2018 Jun;13(6):e1700618. doi: 10.1002/biot.201700618. Epub 2018 Feb 9. Review.


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