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Items: 1 to 50 of 266

1.
2.

A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.

Rangwala SM, D'Aquino K, Zhang YM, Bader L, Edwards W, Zheng S, Eckardt A, Lacombe A, Pick R, Moreno V, Kang L, Jian W, Arnoult E, Case M, Jenkinson C, Chi E, Swanson RV, Kievit P, Grove K, Macielag M, Erion MD, SinhaRoy R, Leonard JN.

Cell Metab. 2019 Apr 2;29(4):837-843.e5. doi: 10.1016/j.cmet.2019.01.017. Epub 2019 Feb 14.

PMID:
30773465
3.

High Selectivity and Sensitivity of Oligomeric p-Phenylene Ethynylenes for Detecting Fibrillar and Prefibrillar Amyloid Protein Aggregates.

Fanni AM, Monge FA, Lin CY, Thapa A, Bhaskar K, Whitten DG, Chi EY.

ACS Chem Neurosci. 2019 Mar 20;10(3):1813-1825. doi: 10.1021/acschemneuro.8b00719. Epub 2019 Feb 6.

PMID:
30657326
4.

Computational Study of the Driving Forces and Dynamics of Curcumin Binding to Amyloid-β Protofibrils.

Martin TD, Malagodi AJ, Chi EY, Evans DG.

J Phys Chem B. 2019 Jan 24;123(3):551-560. doi: 10.1021/acs.jpcb.8b09185. Epub 2019 Jan 9.

PMID:
30571122
5.

A negative feedback loop between nuclear factor 90 (NF90) and an anti-oncogenic microRNA, miR-7.

Higuchi T, Morisawa K, Todaka H, Lai S, Chi E, Matsukawa K, Sugiyama Y, Sakamoto S.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1819-1824. doi: 10.1016/j.bbrc.2018.07.119. Epub 2018 Jul 27.

PMID:
30060955
6.

A Retrospective: 10 Years of Oligo(phenylene-ethynylene) Electrolytes: Demystifying Nanomaterials.

Whitten DG, Tang Y, Zhou Z, Yang J, Wang Y, Hill EH, Pappas HC, Donabedian PL, Chi EY.

Langmuir. 2019 Jan 15;35(2):307-325. doi: 10.1021/acs.langmuir.8b01810. Epub 2018 Aug 14.

PMID:
30056722
7.

Substituent, Charge, and Size Effects on the Fluorogenic Performance of Amyloid Ligands: A Small-Library Screening Study.

Donabedian PL, Evanoff M, Monge FA, Whitten DG, Chi EY.

ACS Omega. 2017 Jul 31;2(7):3192-3200. doi: 10.1021/acsomega.7b00231. Epub 2017 Jul 6.

8.

Bayesian methods for analysis of biosimilar phase III trials.

Weiss RE, Xia X, Zhang N, Wang H, Chi E.

Stat Med. 2018 Sep 10;37(20):2938-2953. doi: 10.1002/sim.7814. Epub 2018 May 23.

PMID:
29797335
9.

Enhanced Ordering in Monolayers Containing Glycosphingolipids: Impact of Carbohydrate Structure.

Watkins EB, Frey SL, Chi EY, Cao KD, Pacuszka T, Majewski J, Lee KYC.

Biophys J. 2018 Mar 13;114(5):1103-1115. doi: 10.1016/j.bpj.2017.12.044.

10.

Methods for efficient analysis of tocopherols, tocotrienols and their metabolites in animal samples with HPLC-EC.

Lee MJ, Feng W, Yang L, Chen YK, Chi E, Liu A, Yang CS.

J Food Drug Anal. 2018 Jan;26(1):318-329. doi: 10.1016/j.jfda.2017.07.012. Epub 2017 Aug 19.

11.

Structural insights into humanization of anti-tissue factor antibody 10H10.

Teplyakov A, Obmolova G, Malia TJ, Raghunathan G, Martinez C, Fransson J, Edwards W, Connor J, Husovsky M, Beck H, Chi E, Fenton S, Zhou H, Almagro JC, Gilliland GL.

MAbs. 2018 Feb/Mar;10(2):269-277. doi: 10.1080/19420862.2017.1412026. Epub 2018 Jan 2.

12.

Improving the power to establish clinical similarity in a Phase 3 efficacy trial by incorporating prior evidence of analytical and pharmacokinetic similarity.

Zeng D, Pan J, Hu K, Chi E, Lin DY.

J Biopharm Stat. 2018;28(2):320-332. doi: 10.1080/10543406.2017.1397012. Epub 2017 Nov 27.

13.

Detergent-induced self-assembly and controllable photosensitizer activity of diester phenylene ethynylenes.

Donabedian PL, Creyer MN, Monge FA, Schanze KS, Chi EY, Whitten DG.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):7278-7282. doi: 10.1073/pnas.1702513114. Epub 2017 Jun 22.

14.

Quality and readability of websites for patient information on tonsillectomy and sleep apnea.

Chi E, Jabbour N, Aaronson NL.

Int J Pediatr Otorhinolaryngol. 2017 Jul;98:1-3. doi: 10.1016/j.ijporl.2017.04.031. Epub 2017 Apr 23.

PMID:
28583484
15.

Durable Response to Immune Checkpoint Blockade in a Platinum-Refractory Patient With Nonseminomatous Germ Cell Tumor.

Chi EA, Schweizer MT.

Clin Genitourin Cancer. 2017 Oct;15(5):e855-e857. doi: 10.1016/j.clgc.2017.04.005. Epub 2017 Apr 12. No abstract available.

PMID:
28465048
16.

Crystallization Behavior of Amorphous Si3N4 and Particle Size Control of the Crystallized α-Si3N4.

Chung YK, Kim SA, Koo JH, Oh HC, Chi EO, Hahn JH, Park C.

J Nanosci Nanotechnol. 2016 May;16(5):5403-9.

PMID:
27483939
17.

Oligomeric Conjugated Polyelectrolytes Display Site-Preferential Binding to an MS2 Viral Capsid.

Martin TD, Hill EH, Whitten DG, Chi EY, Evans DG.

Langmuir. 2016 Nov 29;32(47):12542-12551. Epub 2016 Aug 29.

PMID:
27464311
18.

Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.

Wang H, Liu A, Kuo Y, Chi E, Yang X, Zhang L, Yang CS.

Carcinogenesis. 2016 Jul;37(7):723-730. doi: 10.1093/carcin/bgw054. Epub 2016 May 2.

19.

δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages.

Chen JX, Liu A, Lee MJ, Wang H, Yu S, Chi E, Reuhl K, Suh N, Yang CS.

Mol Carcinog. 2017 Jan;56(1):172-183. doi: 10.1002/mc.22481. Epub 2016 May 13.

20.

Convex biclustering.

Chi EC, Allen GI, Baraniuk RG.

Biometrics. 2017 Mar;73(1):10-19. doi: 10.1111/biom.12540. Epub 2016 May 10.

PMID:
27163413
21.
22.

Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway.

Thapa A, Jett SD, Chi EY.

ACS Chem Neurosci. 2016 Jan 20;7(1):56-68. doi: 10.1021/acschemneuro.5b00214. Epub 2015 Nov 17.

PMID:
26529184
23.

Oligo(p-phenylene ethynylene) Electrolytes: A Novel Molecular Scaffold for Optical Tracking of Amyloids.

Donabedian PL, Pham TK, Whitten DG, Chi EY.

ACS Chem Neurosci. 2015 Sep 16;6(9):1526-35. doi: 10.1021/acschemneuro.5b00086. Epub 2015 Jul 8.

PMID:
26114931
24.

Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's Disease.

Thapa A, Chi EY.

Adv Exp Med Biol. 2015;863:55-77. doi: 10.1007/978-3-319-18365-7_3. Review.

PMID:
26092626
25.

Convex clustering: an attractive alternative to hierarchical clustering.

Chen GK, Chi EC, Ranola JM, Lange K.

PLoS Comput Biol. 2015 May 12;11(5):e1004228. doi: 10.1371/journal.pcbi.1004228. eCollection 2015 May.

26.

Splitting Methods for Convex Clustering.

Chi EC, Lange K.

J Comput Graph Stat. 2015;24(4):994-1013. Epub 2015 Dec 10.

27.
28.

Distance majorization and its applications.

Chi EC, Zhou H, Lange K.

Math Program. 2014 Aug 1;146:409-436.

29.

Preface: issues in biosimilar drug development.

Yao B, Chi E.

J Biopharm Stat. 2014;24(6):1137. doi: 10.1080/10543406.2014.948551. No abstract available.

PMID:
25360866
30.

A Brief Survey of Modern Optimization for Statisticians.

Lange K, Chi EC, Zhou H.

Int Stat Rev. 2014 Apr 1;82(1):46-70.

31.
32.

Stable Estimation of a Covariance Matrix Guided by Nuclear Norm Penalties.

Chi EC, Lange K.

Comput Stat Data Anal. 2014 Dec 1;80:117-128.

33.

Nonparametric tests for evaluation of biosimilarity in variability of follow-on biologics.

Zhang N, Yang J, Chow SC, Chi E.

J Biopharm Stat. 2014;24(6):1239-53. doi: 10.1080/10543406.2014.941991.

PMID:
25036940
34.

Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life.

Edwards W, Fung-Leung WP, Huang C, Chi E, Wu N, Liu Y, Maher MP, Bonesteel R, Connor J, Fellows R, Garcia E, Lee J, Lu L, Ngo K, Scott B, Zhou H, Swanson RV, Wickenden AD.

J Biol Chem. 2014 Aug 15;289(33):22704-14. doi: 10.1074/jbc.M114.568642. Epub 2014 Jun 17.

35.

IMAGING GENETICS VIA SPARSE CANONICAL CORRELATION ANALYSIS.

Chi EC, Allen GI, Zhou H, Kohannim O, Lange K, Thompson PM.

Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31;2013:740-743.

36.

Construction and characterization of E1- and E3-deleted adenovirus vectors expressing two antigens from two separate expression cassettes.

Small JC, Kurupati RK, Zhou X, Bian A, Chi E, Li Y, Xiang Z, Ertl HC.

Hum Gene Ther. 2014 Apr;25(4):328-38. doi: 10.1089/hum.2013.216. Epub 2014 Mar 25.

37.

Regulation of paclitaxel-induced programmed cell death by autophagic induction: A model for cervical cancer.

Chi EY, Viriyapak B, Kwack HS, Lee YK, Kim SI, Lee KH, Park TC.

Obstet Gynecol Sci. 2013 Mar;56(2):84-92. doi: 10.5468/OGS.2013.56.2.84. Epub 2013 Mar 12.

38.

CD8+ T cell recognition of epitopes within the capsid of adeno-associated virus 8-based gene transfer vectors depends on vectors' genome.

Wu TL, Li H, Faust SM, Chi E, Zhou S, Wright F, High KA, Ertl HC.

Mol Ther. 2014 Jan;22(1):42-51. doi: 10.1038/mt.2013.218. Epub 2013 Sep 30.

39.

Membrane-mediated neuroprotection by curcumin from amyloid-β-peptide-induced toxicity.

Thapa A, Vernon BC, De la Peña K, Soliz G, Moreno HA, López GP, Chi EY.

Langmuir. 2013 Sep 17;29(37):11713-23. doi: 10.1021/la4020459. Epub 2013 Sep 4.

PMID:
24004419
40.

When worlds collide: interactions at the interface between biological systems and synthetic cationic conjugated polyelectrolytes and oligomers.

Wang Y, Schanze KS, Chi EY, Whitten DG.

Langmuir. 2013 Aug 27;29(34):10635-47. doi: 10.1021/la4012263. Epub 2013 Jun 20.

PMID:
23738803
41.

Comparison of the Amino-Acid Content in Pharmacopuncture Extracts Taken from a Scorpion's Body and from Its Tail.

Lee JH, Shin JS, Chi EH, Lee IH.

J Pharmacopuncture. 2013 Jun;16(2):33-40. doi: 10.3831/KPI.2013.16.007.

42.

Antimicrobial activity of cationic conjugated polyelectrolytes and oligomers against Saccharomyces cerevisiae vegetative cells and ascospores.

Wang Y, Chi EY, Natvig DO, Schanze KS, Whitten DG.

ACS Appl Mater Interfaces. 2013 Jun 12;5(11):4555-61. doi: 10.1021/am400220s. Epub 2013 Mar 19.

PMID:
23510401
43.

Key role of group v secreted phospholipase A2 in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.

Henderson WR Jr, Ye X, Lai Y, Ni Z, Bollinger JG, Tien YT, Chi EY, Gelb MH.

PLoS One. 2013;8(2):e56172. doi: 10.1371/journal.pone.0056172. Epub 2013 Feb 25.

44.

Assessing Similarity to Existing Drugs to Decide Whether to Continue Drug Development.

Ma GJ, Chi E, Ibrahim JG, Parker RA.

Stat Biopharm Res. 2012 Jan 1;4(3):293-300. Epub 2012 Aug 30.

45.

Understanding the dark and light-enhanced bactericidal action of cationic conjugated polyelectrolytes and oligomers.

Wang Y, Jett SD, Crum J, Schanze KS, Chi EY, Whitten DG.

Langmuir. 2013 Jan 15;29(2):781-92. doi: 10.1021/la3044889. Epub 2013 Jan 3.

46.

Genotype imputation via matrix completion.

Chi EC, Zhou H, Chen GK, Del Vecchyo DO, Lange K.

Genome Res. 2013 Mar;23(3):509-18. doi: 10.1101/gr.145821.112. Epub 2012 Dec 10.

47.

Effect of detergents on the thermal behavior of elastin-like polypeptides.

Thapa A, Han W, Simons RH, Chilkoti A, Chi EY, López GP.

Biopolymers. 2013 Jan;99(1):55-62. doi: 10.1002/bip.22137.

48.

An adapted F-test for homogeneity of variability in follow-on biological products.

Yang J, Zhang N, Chow SC, Chi E.

Stat Med. 2013 Feb 10;32(3):415-23. doi: 10.1002/sim.5568. Epub 2012 Aug 30.

PMID:
22933180
49.

Impact of variability on the choice of biosimilarity limits in assessing follow-on biologics.

Zhang N, Yang J, Chow SC, Endrenyi L, Chi E.

Stat Med. 2013 Feb 10;32(3):424-33. doi: 10.1002/sim.5567. Epub 2012 Aug 30.

PMID:
22933127
50.

High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.

Higuchi T, Sakamoto S, Kakinuma Y, Kai S, Yagyu K, Todaka H, Chi E, Okada S, Ujihara T, Morisawa K, Ono M, Sugiyama Y, Ishida W, Fukushima A, Tsuda M, Agata Y, Taniguchi T.

PLoS One. 2012;7(8):e43340. doi: 10.1371/journal.pone.0043340. Epub 2012 Aug 17.

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