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Items: 18

1.

CHD4 regulates the DNA damage response and RAD51 expression in glioblastoma.

McKenzie LD, LeClair JW, Miller KN, Strong AD, Chan HL, Oates EL, Ligon KL, Brennan CW, Chheda MG.

Sci Rep. 2019 Mar 14;9(1):4444. doi: 10.1038/s41598-019-40327-w.

2.

Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress.

Gelman SJ, Naser F, Mahieu NG, McKenzie LD, Dunn GP, Chheda MG, Patti GJ.

Cell Rep. 2018 Jan 9;22(2):512-522. doi: 10.1016/j.celrep.2017.12.050.

3.

Correction: Zika virus has oncolytic activity against glioblastoma stem cells.

Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG.

J Exp Med. 2017 Oct 2;214(10):3145. doi: 10.1084/jem.2017109309122017c. Epub 2017 Sep 15. No abstract available.

4.

Zika virus has oncolytic activity against glioblastoma stem cells.

Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG.

J Exp Med. 2017 Oct 2;214(10):2843-2857. doi: 10.1084/jem.20171093. Epub 2017 Sep 5. Erratum in: J Exp Med. 2017 Sep 15;:.

5.

Using Epigenetic Reprogramming to Treat Pediatric Brain Cancer.

Chheda MG, Gutmann DH.

Cancer Cell. 2017 May 8;31(5):609-611. doi: 10.1016/j.ccell.2017.04.008.

6.

Impact of concurrent chemotherapy with radiation therapy for elderly patients with newly diagnosed glioblastoma: a review of the National Cancer Data Base.

Huang J, Samson P, Perkins SM, Ansstas G, Chheda MG, DeWees TA, Tsien CI, Robinson CG, Campian JL.

J Neurooncol. 2017 Feb;131(3):593-601. doi: 10.1007/s11060-016-2331-6. Epub 2016 Nov 14.

PMID:
27844308
7.

Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study.

Chheda MG, Wen PY, Hochberg FH, Chi AS, Drappatz J, Eichler AF, Yang D, Beroukhim R, Norden AD, Gerstner ER, Betensky RA, Batchelor TT.

J Neurooncol. 2015 Feb;121(3):627-34. doi: 10.1007/s11060-014-1680-2. Epub 2014 Dec 13.

8.

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.

Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RG, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG.

Cell Rep. 2014 Jan 30;6(2):313-24. doi: 10.1016/j.celrep.2013.12.032. Epub 2014 Jan 16.

9.

Integrative functional genomics identifies RINT1 as a novel GBM oncogene.

Quayle SN, Chheda MG, Shukla SA, Wiedemeyer R, Tamayo P, Dewan RW, Zhuang L, Huang-Hobbs E, Haidar S, Xiao Y, Ligon KL, Hahn WC, Chin L.

Neuro Oncol. 2012 Nov;14(11):1325-31. doi: 10.1093/neuonc/nos246. Epub 2012 Oct 16.

10.

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors.

Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, Nghiemphu PL, Kubek S, Oldrini B, Chheda MG, Yannuzzi N, Tao H, Zhu S, Iwanami A, Kuga D, Dang J, Pedraza A, Brennan CW, Heguy A, Liau LM, Lieberman F, Yung WK, Gilbert MR, Reardon DA, Drappatz J, Wen PY, Lamborn KR, Chang SM, Prados MD, Fine HA, Horvath S, Wu N, Lassman AB, DeAngelis LM, Yong WH, Kuhn JG, Mischel PS, Mehta MP, Cloughesy TF, Mellinghoff IK.

Cancer Discov. 2012 May;2(5):458-71. doi: 10.1158/2159-8290.CD-11-0284. Epub 2012 Mar 31.

11.

Emerging insights into the molecular and cellular basis of glioblastoma.

Dunn GP, Rinne ML, Wykosky J, Genovese G, Quayle SN, Dunn IF, Agarwalla PK, Chheda MG, Campos B, Wang A, Brennan C, Ligon KL, Furnari F, Cavenee WK, Depinho RA, Chin L, Hahn WC.

Genes Dev. 2012 Apr 15;26(8):756-84. doi: 10.1101/gad.187922.112. Review.

12.

Studying a complex tumor: potential and pitfalls.

Zheng S, Chheda MG, Verhaak RG.

Cancer J. 2012 Jan-Feb;18(1):107-14. doi: 10.1097/PPO.0b013e3182431c57. Review.

13.

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM.

Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, Zhuang L, Rosenbluh J, Chen S, Xiao Y, Shapiro GI, Hahn WC, Chin L.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11501-6. doi: 10.1073/pnas.1001613107. Epub 2010 Jun 7.

14.

PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.

Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, Brennan C, Wang YA, Hahn WC, Chin L, DePinho RA.

Cancer Cell. 2010 May 18;17(5):497-509. doi: 10.1016/j.ccr.2010.03.020.

15.

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.

Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC.

Nature. 2008 Sep 25;455(7212):547-51. doi: 10.1038/nature07179. Epub 2008 Sep 14.

16.

Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.

Chheda MG, Drappatz J, Greenberger NJ, Kesari S, Weiss SE, Gigas DC, Doherty LM, Wen PY.

Neurology. 2007 Mar 20;68(12):955-6. No abstract available.

PMID:
17372135
17.

Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits.

Carmine A, Chheda MG, J├Ânsson EG, Sedvall GC, Farde L, Gustavsson JP, Bergman H, Anvret M, Buervenich S, Olson L.

Psychiatr Genet. 2003 Mar;13(1):23-8.

PMID:
12605097
18.

Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex.

Chheda MG, Ashery U, Thakur P, Rettig J, Sheng ZH.

Nat Cell Biol. 2001 Apr;3(4):331-8.

PMID:
11283605

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