Sort by
Items per page

Send to

Choose Destination

Search results

Items: 12


S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit.

Liu C, Zhang CW, Lo SQ, Ang ST, Chew KCM, Yu D, Chai BH, Tan B, Tsang F, Tai YK, Tan BWQ, Liang MC, Tan HT, Tang JY, Lai MKP, Chua JJE, Chung MCM, Khanna S, Lim KL, Soong TW.

J Neurosci. 2018 Sep 26;38(39):8364-8377. doi: 10.1523/JNEUROSCI.3262-17.2018. Epub 2018 Aug 13.


Bidirectional modulation of hippocampal synaptic plasticity by Dopaminergic D4-receptors in the CA1 area of hippocampus.

Navakkode S, Chew KCM, Tay SJN, Lin Q, Behnisch T, Soong TW.

Sci Rep. 2017 Nov 14;7(1):15571. doi: 10.1038/s41598-017-15917-1.


Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain.

Zhang CW, Tai YK, Chai BH, Chew KCM, Ang ET, Tsang F, Tan BWQ, Hong ETE, Asad ABA, Chuang KH, Lim KL, Soong TW.

Neuromolecular Med. 2017 Sep;19(2-3):375-386. doi: 10.1007/s12017-017-8451-0. Epub 2017 Jul 10.


Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination.

Lim GG, Chew KC, Ng XH, Henry-Basil A, Sim RW, Tan JM, Chai C, Lim KL.

PLoS One. 2013 Sep 2;8(9):e73235. doi: 10.1371/journal.pone.0073235. eCollection 2013.


Enhanced autophagy from chronic toxicity of iron and mutant A53T α-synuclein: implications for neuronal cell death in Parkinson disease.

Chew KC, Ang ET, Tai YK, Tsang F, Lo SQ, Ong E, Ong WY, Shen HM, Lim KL, Dawson VL, Dawson TM, Soong TW.

J Biol Chem. 2011 Sep 23;286(38):33380-9. doi: 10.1074/jbc.M111.268409. Epub 2011 Jul 27.


Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination.

Chew KC, Matsuda N, Saisho K, Lim GG, Chai C, Tan HM, Tanaka K, Lim KL.

PLoS One. 2011;6(5):e19720. doi: 10.1371/journal.pone.0019720. Epub 2011 May 23.


Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.

Wang C, Ko HS, Thomas B, Tsang F, Chew KC, Tay SP, Ho MW, Lim TM, Soong TW, Pletnikova O, Troncoso J, Dawson VL, Dawson TM, Lim KL.

Hum Mol Genet. 2005 Dec 15;14(24):3885-97. Epub 2005 Nov 8.


Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.

Lim KL, Chew KC, Tan JM, Wang C, Chung KK, Zhang Y, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM.

J Neurosci. 2005 Feb 23;25(8):2002-9.


The 350-fold compacted Fugu parkin gene is structurally and functionally similar to human Parkin.

Yu WP, Tan JM, Chew KC, Oh T, Kolatkar P, Venkatesh B, Dawson TM, Leong Lim K.

Gene. 2005 Feb 14;346:97-104. Epub 2004 Dec 15.


SCORPION, a molecular database of scorpion toxins.

Srinivasan KN, Gopalakrishnakone P, Tan PT, Chew KC, Cheng B, Kini RM, Koh JL, Seah SH, Brusic V.

Toxicon. 2002 Jan;40(1):23-31. Review.


Lumbosacral nerve root avulsion.

Chin CH, Chew KC.

Injury. 1997 Nov-Dec;28(9-10):674-8.


Supplemental Content

Support Center