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First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma.

Stadtmauer EA, Cohen AD, Weber K, Lacey SF, Gonzalez VE, Melenhorst JJ, Fraietta JA, Plesa G, Shea J, Matlawski T, Cervini A, Mangan P, Gaymon A, Desjardins S, Lancaster E, Salas-Mckee J, Suhoski MM, Fesnak A, O'Rourke M, Lamontagne A, Siegel DL, Young RM, Chew A, Nobles CL, Bushman FD, Chang HY, Satpathy AT, Zhao Y, Hwang WT, Hexner EO, June CH.

Blood. 2019 Nov 13;134(Supplement_1):49. doi: 10.1182/blood-2019-122374.


Double optical gating for generating high flux isolated attosecond pulses in the soft X-ray regime.

Li J, Chew A, Hu S, White J, Ren X, Han S, Yin Y, Wang Y, Wu Y, Chang Z.

Opt Express. 2019 Oct 14;27(21):30280-30286. doi: 10.1364/OE.27.030280.


Worry about Performance: Unravelling the Relationship between 'Doing More' and 'Doing Better'.

Heyzer L, Ali NB, Chew AP, Chan M, Lim WS.

J Nutr Health Aging. 2019;23(9):843-848. doi: 10.1007/s12603-019-1225-7.


Prospective qualification of early cerebral biomarkers in a randomised trial of treatment with xenon combined with moderate hypothermia after birth asphyxia.

Azzopardi D, Chew AT, Deierl A, Huertas A, Robertson NJ, Tusor N, Edwards AD.

EBioMedicine. 2019 Sep;47:484-491. doi: 10.1016/j.ebiom.2019.08.034. Epub 2019 Aug 23.


Integration of Genetic and Biometric Risk Factors for Detection of Primary Angle-Closure Glaucoma.

Nongpiur ME, Khor CC, Cheng CY, Husain R, Boey PY, Chew A, Ho CL, Wong TT, Perera S, Wong TY, Vithana EN, Aung T.

Am J Ophthalmol. 2019 Aug 1. pii: S0002-9394(19)30383-6. doi: 10.1016/j.ajo.2019.07.022. [Epub ahead of print]


Prescribing health information - the development and evaluation of a smartphone app providing guidance and management advice for a feverish child.

Chew A, Koshy A, Lim E.

Future Healthc J. 2019 Mar;6(Suppl 1):90. doi: 10.7861/futurehosp.6-1-s90. No abstract available. Erratum in: Future Healthc J. 2019 Oct;6(3):220.


Quantifying the Stability of the Hydronium Ion in Organic Solvents With Molecular Dynamics Simulations.

Chew AK, Van Lehn RC.

Front Chem. 2019 Jun 19;7:439. doi: 10.3389/fchem.2019.00439. eCollection 2019.


Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.

Phoo WW, Zhang Z, Wirawan M, Chew EJC, Chew ABL, Kouretova J, Steinmetzer T, Luo D.

Antiviral Res. 2018 Dec;160:17-24. doi: 10.1016/j.antiviral.2018.10.006. Epub 2018 Oct 10.


Long-term prescribing of nitrofurantoin for urinary tract infections (UTI) in veterans with spinal cord injury (SCI).

Chew AB, Suda KJ, Patel UC, Fitzpatrick MA, Ramanathan S, Burns SP, Evans CT.

J Spinal Cord Med. 2019 Jul;42(4):485-493. doi: 10.1080/10790268.2018.1488096. Epub 2018 Jul 9.


A new prognostic model for myeloma patients relapsing from upfront autologous transplantation based on ISS and PFS1.

Chavda SJ, Maciocia PM, Mesiri P, Counsell N, Kothari J, Bird A, Mariner C, Chew A, Clesham K, Moore S, Percy L, Rismani A, D'Sa S, Rabin N, Popat R, Yong K.

Br J Haematol. 2019 Apr;185(2):350-353. doi: 10.1111/bjh.15487. Epub 2018 Jul 9. No abstract available.


Causes of death among children aged 5-14 years in the WHO European Region: a systematic analysis for the Global Burden of Disease Study 2016.

Kyu HH, Stein CE, Boschi Pinto C, Rakovac I, Weber MW, Dannemann Purnat T, Amuah JE, Glenn SD, Cercy K, Biryukov S, Gold AL, Chew A, Mooney MD, O'Rourke KF, Sligar A, Murray CJL, Mokdad AH, Naghavi M.

Lancet Child Adolesc Health. 2018 May;2(5):321-337. doi: 10.1016/S2352-4642(18)30095-6.


Use of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality.

Alonso-Caneiro D, Sampson DM, Chew AL, Collins MJ, Chen FK.

Biomed Opt Express. 2018 Jan 18;9(2):679-693. doi: 10.1364/BOE.9.000679. eCollection 2018 Feb 1.


Agreement in Cone Density Derived from Gaze-Directed Single Images Versus Wide-Field Montage Using Adaptive Optics Flood Illumination Ophthalmoscopy.

Chew AL, Sampson DM, Kashani I, Chen FK.

Transl Vis Sci Technol. 2017 Dec 22;6(6):9. doi: 10.1167/tvst.6.6.9. eCollection 2017 Dec.


Three-Dimensional Static Articulation Accuracy of Virtual Models - Part I: System Trueness and Precision.

Yee SHX, Esguerra RJ, Chew AAQ, Wong KM, Tan KBC.

J Prosthodont. 2018 Feb;27(2):129-136. doi: 10.1111/jopr.12723. Epub 2017 Dec 13.


Exploring the multiple-hit hypothesis of preterm white matter damage using diffusion MRI.

Barnett ML, Tusor N, Ball G, Chew A, Falconer S, Aljabar P, Kimpton JA, Kennea N, Rutherford M, David Edwards A, Counsell SJ.

Neuroimage Clin. 2017 Nov 21;17:596-606. doi: 10.1016/j.nicl.2017.11.017. eCollection 2018.


Three-Dimensional Static Articulation Accuracy of Virtual Models-Part II: Effect of Model Scanner-CAD Systems and Articulation Method.

Yee SHX, Esguerra RJ, Chew AAQ, Wong KM, Tan KBC.

J Prosthodont. 2018 Feb;27(2):137-144. doi: 10.1111/jopr.12725. Epub 2017 Dec 6.


Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology Patients.

Marcucci KT, Jadlowsky JK, Hwang WT, Suhoski-Davis M, Gonzalez VE, Kulikovskaya I, Gupta M, Lacey SF, Plesa G, Chew A, Melenhorst JJ, Levine BL, June CH.

Mol Ther. 2018 Jan 3;26(1):269-279. doi: 10.1016/j.ymthe.2017.10.012. Epub 2017 Oct 20.


Perifoveal interdigitation zone loss in hydroxychloroquine toxicity leads to subclinical bull's eye lesion appearance on near-infrared reflectance imaging.

Chew AL, Sampson DM, Chelva E, Khan JC, Chen FK.

Doc Ophthalmol. 2018 Feb;136(1):57-68. doi: 10.1007/s10633-017-9615-9. Epub 2017 Nov 9.


Punctate White Matter Lesions Associated With Altered Brain Development And Adverse Motor Outcome In Preterm Infants.

Tusor N, Benders MJ, Counsell SJ, Nongena P, Ederies MA, Falconer S, Chew A, Gonzalez-Cinca N, Hajnal JV, Gangadharan S, Chatzi V, Kersbergen KJ, Kennea N, Azzopardi DV, Edwards AD.

Sci Rep. 2017 Oct 16;7(1):13250. doi: 10.1038/s41598-017-13753-x.


Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation.

Edwards AD, Redshaw ME, Kennea N, Rivero-Arias O, Gonzales-Cinca N, Nongena P, Ederies M, Falconer S, Chew A, Omar O, Hardy P, Harvey ME, Eddama O, Hayward N, Wurie J, Azzopardi D, Rutherford MA, Counsell S; ePrime Investigators.

Arch Dis Child Fetal Neonatal Ed. 2018 Jan;103(1):F15-F21. doi: 10.1136/archdischild-2017-313102. Epub 2017 Oct 7.


Erratum: 53-attosecond X-ray pulses reach the carbon K-edge.

Li J, Ren X, Yin Y, Zhao K, Chew A, Cheng Y, Cunningham E, Wang Y, Hu S, Wu Y, Chini M, Chang Z.

Nat Commun. 2017 Oct 2;8(1):794. doi: 10.1038/s41467-017-01281-1.


Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products.

Cornetta K, Duffy L, Turtle CJ, Jensen M, Forman S, Binder-Scholl G, Fry T, Chew A, Maloney DG, June CH.

Mol Ther. 2018 Jan 3;26(1):280-288. doi: 10.1016/j.ymthe.2017.09.008. Epub 2017 Sep 12.


High-harmonic generation in amorphous solids.

You YS, Yin Y, Wu Y, Chew A, Ren X, Zhuang F, Gholam-Mirzaei S, Chini M, Chang Z, Ghimire S.

Nat Commun. 2017 Sep 28;8(1):724. doi: 10.1038/s41467-017-00989-4.


Sequential Doping Reveals the Importance of Amorphous Chain Rigidity in Charge Transport of Semi-Crystalline Polymers.

Chew AR, Ghosh R, Shang Z, Spano FC, Salleo A.

J Phys Chem Lett. 2017 Oct 19;8(20):4974-4980. doi: 10.1021/acs.jpclett.7b01989. Epub 2017 Sep 28.


Generation of octave-spanning mid-infrared pulses from cascaded second-order nonlinear processes in a single crystal.

Yin Y, Ren X, Chew A, Li J, Wang Y, Zhuang F, Wu Y, Chang Z.

Sci Rep. 2017 Sep 11;7(1):11097. doi: 10.1038/s41598-017-11652-9.


Expression of stable and active human DNA topoisomerase I in Pichia pastoris.

Chan MK, Lim SK, Miswan N, Chew AL, Noordin R, Khoo BY.

Protein Expr Purif. 2018 Jan;141:52-62. doi: 10.1016/j.pep.2017.09.003. Epub 2017 Sep 8.


53-attosecond X-ray pulses reach the carbon K-edge.

Li J, Ren X, Yin Y, Zhao K, Chew A, Cheng Y, Cunningham E, Wang Y, Hu S, Wu Y, Chini M, Chang Z.

Nat Commun. 2017 Aug 4;8(1):186. doi: 10.1038/s41467-017-00321-0. Erratum in: Nat Commun. 2017 Oct 2;8(1):794.


Multimodal image analysis of clinical influences on preterm brain development.

Ball G, Aljabar P, Nongena P, Kennea N, Gonzalez-Cinca N, Falconer S, Chew ATM, Harper N, Wurie J, Rutherford MA, Counsell SJ, Edwards AD.

Ann Neurol. 2017 Aug;82(2):233-246. doi: 10.1002/ana.24995. Epub 2017 Aug 19.


Language ability in preterm children is associated with arcuate fasciculi microstructure at term.

Salvan P, Tournier JD, Batalle D, Falconer S, Chew A, Kennea N, Aljabar P, Dehaene-Lambertz G, Arichi T, Edwards AD, Counsell SJ.

Hum Brain Mapp. 2017 Aug;38(8):3836-3847. doi: 10.1002/hbm.23632. Epub 2017 May 4.


A Rabbit Model Study to Determine the Efficacy of a Prototype Corneal Endothelium Protector during Cataract Surgery.

Chew ACY, Chan A, Nongpiur ME, Peh G, Barathi VA, Lwin NC, Ong C, Perera S.

J Ophthalmol. 2017;2017:6906139. doi: 10.1155/2017/6906139. Epub 2017 Mar 29.


Laser waveform control of extreme ultraviolet high harmonics from solids.

You YS, Wu M, Yin Y, Chew A, Ren X, Gholam-Mirzaei S, Browne DA, Chini M, Chang Z, Schafer KJ, Gaarde MB, Ghimire S.

Opt Lett. 2017 May 1;42(9):1816-1819. doi: 10.1364/OL.42.001816.


Acute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy.

Chen FK, Chew AL, Zhang D, Chen SC, Chelva E, Chandrasekera E, Koay EMH, Forrester J, McLenachan S.

Doc Ophthalmol. 2017 Jun;134(3):227-235. doi: 10.1007/s10633-017-9587-9. Epub 2017 Apr 5.


Towards Terawatt Sub-Cycle Long-Wave Infrared Pulses via Chirped Optical Parametric Amplification and Indirect Pulse Shaping.

Yin Y, Chew A, Ren X, Li J, Wang Y, Wu Y, Chang Z.

Sci Rep. 2017 Apr 3;8:45794. doi: 10.1038/srep45794.


The Use of Microperimetry to Detect Functional Progression in Non-Neovascular Age-Related Macular Degeneration: A Systematic Review.

Wong EN, Chew AL, Morgan WH, Patel PJ, Chen FK.

Asia Pac J Ophthalmol (Phila). 2017 Jan-Feb;6(1):70-79. doi: 10.22608/APO.201643. Review.


FUNDUS AUTOFLUORESCENCE IN RUBELLA RETINOPATHY: Correlation With Photoreceptor Structure and Function.

Bukowska DM, Wan SL, Chew AL, Chelva E, Tang I, Mackey DA, Chen FK.

Retina. 2017 Jan;37(1):124-134. doi: 10.1097/IAE.0000000000001130.


Enhanced Visualization of Subtle Outer Retinal Pathology by En Face Optical Coherence Tomography and Correlation with Multi-Modal Imaging.

Sampson DM, Alonso-Caneiro D, Chew AL, Lamey T, McLaren T, De Roach J, Chen FK.

PLoS One. 2016 Dec 13;11(12):e0168275. doi: 10.1371/journal.pone.0168275. eCollection 2016.


Normative biometry of the fetal brain using magnetic resonance imaging.

Kyriakopoulou V, Vatansever D, Davidson A, Patkee P, Elkommos S, Chew A, Martinez-Biarge M, Hagberg B, Damodaram M, Allsop J, Fox M, Hajnal JV, Rutherford MA.

Brain Struct Funct. 2017 Jul;222(5):2295-2307. doi: 10.1007/s00429-016-1342-6. Epub 2016 Nov 24.


High-energy two-cycle pulses at 3.2 μm by a broadband-pumped dual-chirped optical parametric amplification.

Yin Y, Li J, Ren X, Wang Y, Chew A, Chang Z.

Opt Express. 2016 Oct 31;24(22):24989-24998. doi: 10.1364/OE.24.024989.


Inherently variable responses to glucocorticoid stress among endogenous retroviruses isolated from 23 mouse strains.

Hsu K, Lee YK, Chew A, Chiu S, Lim D, Greenhalgh DG, Cho K.

Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt B):2594-2600. doi: 10.1016/j.bbadis.2016.10.026. Epub 2016 Nov 3.


Three-Dimensional Accuracy of Digital Implant Impressions: Effects of Different Scanners and Implant Level.

Chew AA, Esguerra RJ, Teoh KH, Wong KM, Ng SD, Tan KB.

Int J Oral Maxillofac Implants. 2017 Jan/Feb;32(1):70-80. doi: 10.11607/jomi.4942. Epub 2016 Oct 5.


Health in times of uncertainty in the eastern Mediterranean region, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Mokdad AH, Forouzanfar MH, Daoud F, El Bcheraoui C, Moradi-Lakeh M, Khalil I, Afshin A, Tuffaha M, Charara R, Barber RM, Wagner J, Cercy K, Kravitz H, Coates MM, Robinson M, Estep K, Steiner C, Jaber S, Mokdad AA, O'Rourke KF, Chew A, Kim P, El Razek MM, Abdalla S, Abd-Allah F, Abraham JP, Abu-Raddad LJ, Abu-Rmeileh NM, Al-Nehmi AA, Akanda AS, Al Ahmadi H, Al Khabouri MJ, Al Lami FH, Al Rayess ZA, Alasfoor D, AlBuhairan FS, Aldhahri SF, Alghnam S, Alhabib S, Al-Hamad N, Ali R, Ali SD, Alkhateeb M, AlMazroa MA, Alomari MA, Al-Raddadi R, Alsharif U, Al-Sheyab N, Alsowaidi S, Al-Thani M, Altirkawi KA, Amare AT, Amini H, Ammar W, Anwari P, Asayesh H, Asghar R, Assabri AM, Assadi R, Bacha U, Badawi A, Bakfalouni T, Basulaiman MO, Bazargan-Hejazi S, Bedi N, Bhakta AR, Bhutta ZA, Bin Abdulhak AA, Boufous S, Bourne RR, Danawi H, Das J, Deribew A, Ding EL, Durrani AM, Elshrek Y, Ibrahim ME, Eshrati B, Esteghamati A, Faghmous IA, Farzadfar F, Feigl AB, Fereshtehnejad SM, Filip I, Fischer F, Gankpé FG, Ginawi I, Gishu MD, Gupta R, Habash RM, Hafezi-Nejad N, Hamadeh RR, Hamdouni H, Hamidi S, Harb HL, Hassanvand MS, Hedayati MT, Heydarpour P, Hsairi M, Husseini A, Jahanmehr N, Jha V, Jonas JB, Karam NE, Kasaeian A, Kassa NA, Kaul A, Khader Y, Khalifa SE, Khan EA, Khan G, Khoja T, Khosravi A, Kinfu Y, Defo BK, Balaji AL, Lunevicius R, Obermeyer CM, Malekzadeh R, Mansourian M, Marcenes W, Farid HM, Mehari A, Mehio-Sibai A, Memish ZA, Mensah GA, Mohammad KA, Nahas Z, Nasher JT, Nawaz H, Nejjari C, Nisar MI, Omer SB, Parsaeian M, Peprah EK, Pervaiz A, Pourmalek F, Qato DM, Qorbani M, Radfar A, Rafay A, Rahimi K, Rahimi-Movaghar V, Rahman SU, Rai RK, Rana SM, Rao SR, Refaat AH, Resnikoff S, Roshandel G, Saade G, Saeedi MY, Sahraian MA, Saleh S, Sanchez-Riera L, Satpathy M, Sepanlou SG, Setegn T, Shaheen A, Shahraz S, Sheikhbahaei S, Shishani K, Sliwa K, Tavakkoli M, Terkawi AS, Uthman OA, Westerman R, Younis MZ, El Sayed Zaki M, Zannad F, Roth GA, Wang H, Naghavi M, Vos T, Al Rabeeah AA, Lopez AD, Murray CJ.

Lancet Glob Health. 2016 Oct;4(10):e704-13. doi: 10.1016/S2214-109X(16)30168-1. Epub 2016 Aug 25.


Cost-effectiveness modelling of novel oral anticoagulants incorporating real-world elderly patients with atrial fibrillation.

Zhao YJ, Lin L, Zhou HJ, Tan KT, Chew AP, Foo CG, Oh CT, Lim BP, Lim WS.

Int J Cardiol. 2016 Oct 1;220:794-801. doi: 10.1016/j.ijcard.2016.06.087. Epub 2016 Jun 23.


Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway.

Cooley-Andrade O, Cheung K, Chew AN, Connor DE, Parsi K.

Apoptosis. 2016 Jul;21(7):836-45. doi: 10.1007/s10495-016-1252-3.


Abuse and discrimination towards indigenous people in public health care facilities: experiences from rural Guatemala.

Cerón A, Ruano AL, Sánchez S, Chew AS, Díaz D, Hernández A, Flores W.

Int J Equity Health. 2016 May 13;15:77. doi: 10.1186/s12939-016-0367-z.


Global burden of diseases, injuries, and risk factors for young people's health during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Mokdad AH, Forouzanfar MH, Daoud F, Mokdad AA, El Bcheraoui C, Moradi-Lakeh M, Kyu HH, Barber RM, Wagner J, Cercy K, Kravitz H, Coggeshall M, Chew A, O'Rourke KF, Steiner C, Tuffaha M, Charara R, Al-Ghamdi EA, Adi Y, Afifi RA, Alahmadi H, AlBuhairan F, Allen N, AlMazroa M, Al-Nehmi AA, AlRayess Z, Arora M, Azzopardi P, Barroso C, Basulaiman M, Bhutta ZA, Bonell C, Breinbauer C, Degenhardt L, Denno D, Fang J, Fatusi A, Feigl AB, Kakuma R, Karam N, Kennedy E, Khoja TA, Maalouf F, Obermeyer CM, Mattoo A, McGovern T, Memish ZA, Mensah GA, Patel V, Petroni S, Reavley N, Zertuche DR, Saeedi M, Santelli J, Sawyer SM, Ssewamala F, Taiwo K, Tantawy M, Viner RM, Waldfogel J, Zuñiga MP, Naghavi M, Wang H, Vos T, Lopez AD, Al Rabeeah AA, Patton GC, Murray CJ.

Lancet. 2016 Jun 11;387(10036):2383-401. doi: 10.1016/S0140-6736(16)00648-6. Epub 2016 May 9.


Bandgap Restructuring of the Layered Semiconductor Gallium Telluride in Air.

Fonseca JJ, Tongay S, Topsakal M, Chew AR, Lin AJ, Ko C, Luce AV, Salleo A, Wu J, Dubon OD.

Adv Mater. 2016 Aug;28(30):6465-70. doi: 10.1002/adma.201601151. Epub 2016 May 12.


Altered white matter and cortical structure in neonates with antenatally diagnosed isolated ventriculomegaly.

Lockwood Estrin G, Kyriakopoulou V, Makropoulos A, Ball G, Kuhendran L, Chew A, Hagberg B, Martinez-Biarge M, Allsop J, Fox M, Counsell SJ, Rutherford MA.

Neuroimage Clin. 2016 Jan 14;11:139-148. doi: 10.1016/j.nicl.2016.01.012. eCollection 2016.


Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment.

Hexner EO, Luger SM, Reshef R, Jeschke GR, Mangan JK, Frey NV, Frank DM, Richman LP, Vonderheide RH, Aqui NA, Rosenbach M, Zhang Y, Chew A, Loren AW, Stadtmauer EA, Levine BL, June CH, Emerson SG, Porter DL.

Am J Hematol. 2016 May;91(5):453-60. doi: 10.1002/ajh.24303. Epub 2016 Apr 4.


Strain effects on the work function of an organic semiconductor.

Wu Y, Chew AR, Rojas GA, Sini G, Haugstad G, Belianinov A, Kalinin SV, Li H, Risko C, Brédas JL, Salleo A, Frisbie CD.

Nat Commun. 2016 Feb 1;7:10270. doi: 10.1038/ncomms10270.


Semi-automated identification of cones in the human retina using circle Hough transform.

Bukowska DM, Chew AL, Huynh E, Kashani I, Wan SL, Wan PM, Chen FK.

Biomed Opt Express. 2015 Nov 3;6(12):4676-93. doi: 10.1364/BOE.6.004676. eCollection 2015 Dec 1.

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