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Items: 1 to 50 of 213


Nonlinear gene expression-phenotype relationships contribute to variation and clefting in the A/WySn mouse.

Green RM, Leach CL, Diewert VM, Aponte JD, Schmidt EJ, Cheverud JM, Roseman CC, Young NM, Marcucio RS, Hallgrimsson B.

Dev Dyn. 2019 Dec;248(12):1232-1242. doi: 10.1002/dvdy.110. Epub 2019 Sep 14.


The effect of dietary fat on behavior in mice.

Keleher MR, Zaidi R, Patel K, Ahmed A, Bettler C, Pavlatos C, Shah S, Cheverud JM.

J Diabetes Metab Disord. 2018 Nov 22;17(2):297-307. doi: 10.1007/s40200-018-0373-3. eCollection 2018 Dec.


Effects of High-Fat Diet and Body Mass on Bone Morphology and Mechanical Properties in 1100 Advanced Intercross Mice.

Silva MJ, Eekhoff JD, Patel T, Kenney-Hunt JP, Brodt MD, Steger-May K, Scheller EL, Cheverud JM.

J Bone Miner Res. 2019 Apr;34(4):711-725. doi: 10.1002/jbmr.3648. Epub 2019 Jan 7.


A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice.

Keleher MR, Zaidi R, Hicks L, Shah S, Xing X, Li D, Wang T, Cheverud JM.

BMC Genomics. 2018 Dec 7;19(1):888. doi: 10.1186/s12864-018-5327-0.


Evidence for Genetic Contribution to Variation in Posttraumatic Osteoarthritis in Mice.

Chinzei N, Rai MF, Hashimoto S, Schmidt EJ, Takebe K, Cheverud JM, Sandell LJ.

Arthritis Rheumatol. 2019 Mar;71(3):370-381. doi: 10.1002/art.40730. Epub 2019 Jan 25.


The developmental-genetics of canalization.

Hallgrimsson B, Green RM, Katz DC, Fish JL, Bernier FP, Roseman CC, Young NM, Cheverud JM, Marcucio RS.

Semin Cell Dev Biol. 2019 Apr;88:67-79. doi: 10.1016/j.semcdb.2018.05.019. Epub 2018 May 24. Review.


Maternal high-fat diet associated with altered gene expression, DNA methylation, and obesity risk in mouse offspring.

Keleher MR, Zaidi R, Shah S, Oakley ME, Pavlatos C, El Idrissi S, Xing X, Li D, Wang T, Cheverud JM.

PLoS One. 2018 Feb 15;13(2):e0192606. doi: 10.1371/journal.pone.0192606. eCollection 2018.


Developmental nonlinearity drives phenotypic robustness.

Green RM, Fish JL, Young NM, Smith FJ, Roberts B, Dolan K, Choi I, Leach CL, Gordon P, Cheverud JM, Roseman CC, Williams TJ, Marcucio RS, Hallgrímsson B.

Nat Commun. 2017 Dec 6;8(1):1970. doi: 10.1038/s41467-017-02037-7.


Additive genetic variation in the craniofacial skeleton of baboons (genus Papio) and its relationship to body and cranial size.

Joganic JL, Willmore KE, Richtsmeier JT, Weiss KM, Mahaney MC, Rogers J, Cheverud JM.

Am J Phys Anthropol. 2018 Feb;165(2):269-285. doi: 10.1002/ajpa.23349. Epub 2017 Nov 20.


Evolution of the Genotype-to-Phenotype Map and the Cost of Pleiotropy in Mammals.

Porto A, Schmelter R, VandeBerg JL, Marroig G, Cheverud JM.

Genetics. 2016 Dec;204(4):1601-1612. Epub 2016 Oct 26.


Transgenerational cardiology: One way to a baby's heart is through the mother.

Jay PY, Akhirome E, Magnan RA, Zhang MR, Kang L, Qin Y, Ugwu N, Regmi SD, Nogee JM, Cheverud JM.

Mol Cell Endocrinol. 2016 Nov 5;435:94-102. doi: 10.1016/j.mce.2016.08.029. Epub 2016 Aug 20. Review.


Gene expression in human meniscal tears has limited association with early degenerative changes in knee articular cartilage.

Brophy RH, Sandell LJ, Cheverud JM, Rai MF.

Connect Tissue Res. 2017 May - Jul;58(3-4):295-304. doi: 10.1080/03008207.2016.1211114. Epub 2016 Jul 19.


The Genetic Basis of Baculum Size and Shape Variation in Mice.

Schultz NG, Ingels J, Hillhouse A, Wardwell K, Chang PL, Cheverud JM, Lutz C, Lu L, Williams RW, Dean MD.

G3 (Bethesda). 2016 May 3;6(5):1141-51. doi: 10.1534/g3.116.027888.


Multivariate Analysis of Genotype-Phenotype Association.

Mitteroecker P, Cheverud JM, Pavlicev M.

Genetics. 2016 Apr;202(4):1345-63. doi: 10.1534/genetics.115.181339. Epub 2016 Feb 19.


Evolutionary and developmental implications of asymmetric brain folding in a large primate pedigree.

Atkinson EG, Rogers J, Cheverud JM.

Evolution. 2016 Mar;70(3):707-15. doi: 10.1111/evo.12867. Epub 2016 Feb 11.


Modularity: genes, development and evolution.

Melo D, Porto A, Cheverud JM, Marroig G.

Annu Rev Ecol Evol Syst. 2016;47:463-486. doi: 10.1146/annurev-ecolsys-121415-032409. Epub 2016 Sep 7.


Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides.

Nikolskiy I, Conrad DF, Chun S, Fay JC, Cheverud JM, Lawson HA.

BMC Genomics. 2015 May 28;16:415. doi: 10.1186/s12864-015-1592-3.


Genetic loci that regulate ectopic calcification in response to knee trauma in LG/J by SM/J advanced intercross mice.

Rai MF, Schmidt EJ, Hashimoto S, Cheverud JM, Sandell LJ.

J Orthop Res. 2015 Oct;33(10):1412-23. doi: 10.1002/jor.22944. Epub 2015 Jun 19.


Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio).

Atkinson EG, Rogers J, Mahaney MC, Cox LA, Cheverud JM.

Genetics. 2015 Jun;200(2):651-65. doi: 10.1534/genetics.114.173443. Epub 2015 Apr 14.


Rate of evolutionary change in cranial morphology of the marsupial genus Monodelphis is constrained by the availability of additive genetic variation.

Porto A, Sebastião H, Pavan SE, VandeBerg JL, Marroig G, Cheverud JM.

J Evol Biol. 2015 Apr;28(4):973-85. doi: 10.1111/jeb.12628. Epub 2015 Apr 17.


Characterizing the evolutionary path(s) to early Homo.

Schroeder L, Roseman CC, Cheverud JM, Ackermann RR.

PLoS One. 2014 Dec 3;9(12):e114307. doi: 10.1371/journal.pone.0114307. eCollection 2014.


Obituary: Kenneth Alan Bennett (October 3, 1935 - February 6, 2014).

Strier KB, Cheverud JM, Grayson DK.

Am J Phys Anthropol. 2014 Oct;155(2):316-7. doi: 10.1002/ajpa.22583. Epub 2014 Jul 24. No abstract available.


Further evidence for phenotypic signatures of hybridization in descendant baboon populations.

Ackermann RR, Schroeder L, Rogers J, Cheverud JM.

J Hum Evol. 2014 Nov;76:54-62. doi: 10.1016/j.jhevol.2014.05.004. Epub 2014 Jun 13. Erratum in: J Hum Evol. 2015 Mar;80:191.


Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.

Cheverud JM, Lawson HA, Bouckaert K, Kossenkov AV, Showe LC, Cort L, Blankenhorn EP, Bedelbaeva K, Gourevitch D, Zhang Y, Heber-Katz E.

Heredity (Edinb). 2014 May;112(5):508-18. doi: 10.1038/hdy.2013.133. Epub 2014 Feb 26.


The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice.

Partridge CG, Fawcett GL, Wang B, Semenkovich CF, Cheverud JM.

BMC Genomics. 2014 Feb 5;15:99. doi: 10.1186/1471-2164-15-99.


APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions.

Maxwell TJ, Ballantyne CM, Cheverud JM, Guild CS, Ndumele CE, Boerwinkle E.

Genetics. 2013 Dec;195(4):1397-405. doi: 10.1534/genetics.113.157719. Epub 2013 Oct 4.


Genomic correlates of relationship QTL involved in fore- versus hind limb divergence in mice.

Pavlicev M, Wagner GP, Noonan JP, Hallgrímsson B, Cheverud JM.

Genome Biol Evol. 2013;5(10):1926-36. doi: 10.1093/gbe/evt144.


Molecular insight into the association between cartilage regeneration and ear wound healing in genetic mouse models: targeting new genes in regeneration.

Rai MF, Schmidt EJ, McAlinden A, Cheverud JM, Sandell LJ.

G3 (Bethesda). 2013 Nov 6;3(11):1881-91. doi: 10.1534/g3.113.007302.


Genomic imprinting and parent-of-origin effects on complex traits.

Lawson HA, Cheverud JM, Wolf JB.

Nat Rev Genet. 2013 Sep;14(9):609-17. doi: 10.1038/nrg3543. Epub 2013 Aug 6. Review.


On the relationship between ontogenetic and static allometry.

Pélabon C, Bolstad GH, Egset CK, Cheverud JM, Pavlicev M, Rosenqvist G.

Am Nat. 2013 Feb;181(2):195-212. doi: 10.1086/668820. Epub 2013 Jan 14.


Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscus.

Rai MF, Sandell LJ, Cheverud JM, Brophy RH.

Int J Obes (Lond). 2013 Sep;37(9):1238-46. doi: 10.1038/ijo.2012.221. Epub 2013 Jan 15.


Quantitative trait loci affecting liver fat content in mice.

Minkina O, Cheverud JM, Fawcett G, Semenkovich CF, Kenney-Hunt JP.

G3 (Bethesda). 2012 Sep;2(9):1019-25. doi: 10.1534/g3.112.003343. Epub 2012 Sep 1.


Hypothalamic expression of Peg3 gene is associated with maternal care differences between SM/J and LG/J mouse strains.

Chiavegatto S, Sauce B, Ambar G, Cheverud JM, Peripato AC.

Brain Behav. 2012 Jul;2(4):365-76. doi: 10.1002/brb3.58.


Weak genetic relationship between trabecular bone morphology and obesity in mice.

Carson EA, Kenney-Hunt JP, Pavlicev M, Bouckaert KA, Chinn AJ, Silva MJ, Cheverud JM.

Bone. 2012 Jul;51(1):46-53. doi: 10.1016/j.bone.2012.03.031. Epub 2012 Apr 6.


Detecting maternal-effect loci by statistical cross-fostering.

Wolf J, Cheverud JM.

Genetics. 2012 May;191(1):261-77. doi: 10.1534/genetics.111.136440. Epub 2012 Feb 29.


Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred mice.

Hashimoto S, Rai MF, Janiszak KL, Cheverud JM, Sandell LJ.

Osteoarthritis Cartilage. 2012 Jun;20(6):562-71. doi: 10.1016/j.joca.2012.01.022. Epub 2012 Feb 8.


Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny.

Wang JR, de Villena FP, Lawson HA, Cheverud JM, Churchill GA, McMillan L.

Genetics. 2012 Feb;190(2):449-58. doi: 10.1534/genetics.111.132381.


Heritability of articular cartilage regeneration and its association with ear wound healing in mice.

Rai MF, Hashimoto S, Johnson EE, Janiszak KL, Fitzgerald J, Heber-Katz E, Cheverud JM, Sandell LJ.

Arthritis Rheum. 2012 Jul;64(7):2300-10. doi: 10.1002/art.34396.


Genotype-dependent responses to levels of sibling competition over maternal resources in mice.

Hager R, Cheverud JM, Wolf JB.

Heredity (Edinb). 2012 May;108(5):515-20. doi: 10.1038/hdy.2011.115. Epub 2011 Nov 30.


Healing quantitative trait loci in a combined cross analysis using related mouse strain crosses.

Cheverud JM, Lawson HA, Funk R, Zhou J, Blankenhorn EP, Heber-Katz E.

Heredity (Edinb). 2012 Apr;108(4):441-6. doi: 10.1038/hdy.2011.94. Epub 2011 Nov 30.


Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations.

Lawson HA, Cady JE, Partridge C, Wolf JB, Semenkovich CF, Cheverud JM.

PLoS Genet. 2011 Sep;7(9):e1002256. doi: 10.1371/journal.pgen.1002256. Epub 2011 Sep 8.


Disentangling prenatal and postnatal maternal genetic effects reveals persistent prenatal effects on offspring growth in mice.

Wolf JB, Leamy LJ, Roseman CC, Cheverud JM.

Genetics. 2011 Nov;189(3):1069-82. doi: 10.1534/genetics.111.130591. Epub 2011 Sep 2.


The effect of a population bottleneck on the evolution of genetic variance/covariance structure.

Jarvis JP, Cropp SN, Vaughn TT, Pletscher LS, King-Ellison K, Adams-Hunt E, Erickson C, Cheverud JM.

J Evol Biol. 2011 Oct;24(10):2139-52. doi: 10.1111/j.1420-9101.2011.02347.x. Epub 2011 Jul 4.


Neuroanatomic and behavioral traits for autistic disorders in age-specific restricted index selection mice.

Meng L, Lu L, Murphy KM, Yuede CM, Cheverud JM, Csernansky JG, Dong H.

Neuroscience. 2011 Aug 25;189:215-22. doi: 10.1016/j.neuroscience.2011.05.017. Epub 2011 May 26.


Evolution of pleiotropy: epistatic interaction pattern supports a mechanistic model underlying variation in genotype-phenotype map.

Pavlicev M, Norgard EA, Fawcett GL, Cheverud JM.

J Exp Zool B Mol Dev Evol. 2011 Jul 15;316(5):371-85. doi: 10.1002/jez.b.21410. Epub 2011 Apr 1.


Developmental and genetic origins of murine long bone length variation.

Sanger TJ, Norgard EA, Pletscher LS, Bevilacqua M, Brooks VR, Sandell LJ, Cheverud JM.

J Exp Zool B Mol Dev Evol. 2011 Mar 15;316B(2):146-61. doi: 10.1002/jez.b.21388. Epub 2010 Dec 1.


The importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J × SM/J murine model.

Lawson HA, Lee A, Fawcett GL, Wang B, Pletscher LS, Maxwell TJ, Ehrich TH, Kenney-Hunt JP, Wolf JB, Semenkovich CF, Cheverud JM.

Mamm Genome. 2011 Apr;22(3-4):197-208. doi: 10.1007/s00335-010-9313-3. Epub 2011 Jan 6.


Genetic factors and diet affect long-bone length in the F34 LG,SM advanced intercross.

Norgard EA, Lawson HA, Pletscher LS, Wang B, Brooks VR, Wolf JB, Cheverud JM.

Mamm Genome. 2011 Apr;22(3-4):178-96. doi: 10.1007/s00335-010-9311-5. Epub 2010 Dec 19.


Mapping the epistatic network underlying murine reproductive fatpad variation.

Jarvis JP, Cheverud JM.

Genetics. 2011 Feb;187(2):597-610. doi: 10.1534/genetics.110.123505. Epub 2010 Nov 29.


Evolution of adaptive phenotypic variation patterns by direct selection for evolvability.

Pavlicev M, Cheverud JM, Wagner GP.

Proc Biol Sci. 2011 Jun 22;278(1713):1903-12. doi: 10.1098/rspb.2010.2113. Epub 2010 Nov 24.

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