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Items: 1 to 50 of 459

1.

Refractive and corneal responses of young myopic children to short-term orthokeratology treatment with different compression factors.

Wan K, Lau JK, Cheung SW, Cho P.

Cont Lens Anterior Eye. 2019 Nov 5. pii: S1367-0484(19)30012-8. doi: 10.1016/j.clae.2019.10.134. [Epub ahead of print]

PMID:
31704093
2.

Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage.

Dong Z, Yan J, Xu F, Yuan J, Jiang H, Wang H, Chen H, Zhang L, Ye L, Xu J, Shi Y, Yang Z, Cao Y, Chen L, Li Q, Zhao X, Li J, Chen A, Zhang W, Wong HG, Qin Y, Zhao H, Chen Y, Li P, Ma T, Wang WJ, Kwok YK, Jiang Y, Pursley AN, Chung JPW, Hong Y, Kristiansen K, Yang H, Piña-Aguilar RE, Leung TY, Cheung SW, Morton CC, Choy KW, Chen ZJ.

Am J Hum Genet. 2019 Oct 29. pii: S0002-9297(19)30391-X. doi: 10.1016/j.ajhg.2019.10.003. [Epub ahead of print]

PMID:
31679651
3.

Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus.

Cheung SW, Racine CA, Henderson-Sabes J, Demopoulos C, Molinaro AM, Heath S, Nagarajan SS, Bourne AL, Rietcheck JE, Wang SS, Larson PS.

J Neurosurg. 2019 Sep 24:1-10. doi: 10.3171/2019.4.JNS19347. [Epub ahead of print]

PMID:
31553940
4.

Xq22 deletions and correlation with distinct neurological disease traits in females: Further evidence for a contiguous gene syndrome.

Hijazi H, Coelho FS, Gonzaga-Jauregui C, Bernardini L, Mar SS, Manning MA, Hanson-Kahn A, Naidu S, Srivastava S, Lee JA, Jones JR, Friez MJ, Alberico T, Torres B, Fang P, Cheung SW, Song X, Davis-Williams A, Jornlin C, Wight PA, Patyal P, Taube J, Poretti A, Inoue K, Zhang F, Pehlivan D, Carvalho CMB, Hobson GM, Lupski JR.

Hum Mutat. 2019 Aug 26. doi: 10.1002/humu.23902. [Epub ahead of print]

PMID:
31448840
5.

Low-pass genome sequencing versus chromosomal microarray analysis: implementation in prenatal diagnosis.

Wang H, Dong Z, Zhang R, Chau MHK, Yang Z, Tsang KYC, Wong HK, Gui B, Meng Z, Xiao K, Zhu X, Wang Y, Chen S, Leung TY, Cheung SW, Kwok YK, Morton CC, Zhu Y, Choy KW.

Genet Med. 2019 Aug 26. doi: 10.1038/s41436-019-0634-7. [Epub ahead of print]

PMID:
31447483
6.

Weekly Changes in Axial Length and Choroidal Thickness in Children During and Following Orthokeratology Treatment With Different Compression Factors.

Lau JK, Wan K, Cheung SW, Vincent SJ, Cho P.

Transl Vis Sci Technol. 2019 Jul 23;8(4):9. doi: 10.1167/tvst.8.4.9. eCollection 2019 Jul.

7.

The influence of orthokeratology compression factor on ocular higher-order aberrations.

Lau JK, Vincent SJ, Cheung SW, Cho P.

Clin Exp Optom. 2019 Jul 1. doi: 10.1111/cxo.12933. [Epub ahead of print]

PMID:
31264269
8.

Residual Tumor Volume and Location Predict Progression After Primary Subtotal Resection of Sporadic Vestibular Schwannomas: A Retrospective Volumetric Study.

Breshears JD, Morshed RA, Molinaro AM, McDermott MW, Cheung SW, Theodosopoulos PV.

Neurosurgery. 2019 Jun 24. pii: nyz200. doi: 10.1093/neuros/nyz200. [Epub ahead of print]

PMID:
31232426
9.

Repeatability of choroidal thickness measurements with Spectralis OCT images.

Lau JK, Cheung SW, Collins MJ, Cho P.

BMJ Open Ophthalmol. 2019 Apr 23;4(1):e000237. doi: 10.1136/bmjophth-2018-000237. eCollection 2019.

10.

Copy number variant and runs of homozygosity detection by microarrays enabled more precise molecular diagnoses in 11,020 clinical exome cases.

Dharmadhikari AV, Ghosh R, Yuan B, Liu P, Dai H, Al Masri S, Scull J, Posey JE, Jiang AH, He W, Vetrini F, Braxton AA, Ward P, Chiang T, Qu C, Gu S, Shaw CA, Smith JL, Lalani S, Stankiewicz P, Cheung SW, Bacino CA, Patel A, Breman AM, Wang X, Meng L, Xiao R, Xia F, Muzny D, Gibbs RA, Beaudet AL, Eng CM, Lupski JR, Yang Y, Bi W.

Genome Med. 2019 May 17;11(1):30. doi: 10.1186/s13073-019-0639-5.

11.

Cortical-Basal Ganglia-Cerebellar Networks in Unilateral Vocal Fold Paralysis: A Pilot Study.

Perez PL, Cueva KL, Rosen CA, Young VN, Naunheim ML, Yung KC, Schneider SL, Mizuiri D, Klein DJ, Houde JF, Hinkley LB, Nagarajan SS, Cheung SW.

Laryngoscope. 2019 May 9. doi: 10.1002/lary.28004. [Epub ahead of print]

PMID:
31070785
12.

Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome.

Carvalho CMB, Coban-Akdemir Z, Hijazi H, Yuan B, Pendleton M, Harrington E, Beaulaurier J, Juul S, Turner DJ, Kanchi RS, Jhangiani SN, Muzny DM, Gibbs RA; Baylor-Hopkins Center for Mendelian Genomics, Stankiewicz P, Belmont JW, Shaw CA, Cheung SW, Hanchard NA, Sutton VR, Bader PI, Lupski JR.

Genome Med. 2019 Apr 23;11(1):25. doi: 10.1186/s13073-019-0633-y.

13.

Human caudate nucleus subdivisions in tinnitus modulation.

Perez PL, Wang SS, Heath S, Henderson-Sabes J, Mizuiri D, Hinkley LB, Nagarajan SS, Larson PS, Cheung SW.

J Neurosurg. 2019 Feb 8:1-7. doi: 10.3171/2018.10.JNS181659. [Epub ahead of print]

PMID:
30738400
14.

Role of corneal biomechanical properties in predicting of speed of myopic progression in children wearing orthokeratology lenses or single-vision spectacles.

Wan K, Cheung SW, Wolffsohn JS, Orr JB, Cho P.

BMJ Open Ophthalmol. 2018 Dec 27;3(1):e000204. doi: 10.1136/bmjophth-2018-000204. eCollection 2018.

15.

Correction: A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 Sep;21(9):2159-2160. doi: 10.1038/s41436-018-0413-x.

PMID:
30643220
16.

Cortical networks for speech motor control in unilateral vocal fold paralysis.

Naunheim ML, Yung KC, Schneider SL, Henderson-Sabes J, Kothare H, Hinkley LB, Mizuiri D, Klein DJ, Houde JF, Nagarajan SS, Cheung SW.

Laryngoscope. 2019 Sep;129(9):2125-2130. doi: 10.1002/lary.27730. Epub 2018 Dec 20.

PMID:
30570142
17.

Phenotypic association of 15q11.2 CNVs of the region of breakpoints 1-2 (BP1-BP2) in a large cohort of samples referred for genetic diagnosis.

Mohan KN, Cao Y, Pham J, Cheung SW, Hoffner L, Ou ZZ, Surti U, Cook EH, Beaudet AL.

J Hum Genet. 2019 Mar;64(3):253-255. doi: 10.1038/s10038-018-0543-7. Epub 2018 Dec 12.

PMID:
30542208
18.

Functional and Structural Brain Plasticity in Adult Onset Single-Sided Deafness.

Shang Y, Hinkley LB, Cai C, Subramaniam K, Chang YS, Owen JP, Garrett C, Mizuiri D, Mukherjee P, Nagarajan SS, Cheung SW.

Front Hum Neurosci. 2018 Nov 27;12:474. doi: 10.3389/fnhum.2018.00474. eCollection 2018.

19.

Vocal motor control and central auditory impairments in unilateral vocal fold paralysis.

Naunheim ML, Yung KC, Schneider SL, Henderson-Sabes J, Kothare H, Mizuiri D, Klein DJ, Houde JF, Nagarajan SS, Cheung SW.

Laryngoscope. 2019 Sep;129(9):2112-2117. doi: 10.1002/lary.27680. Epub 2018 Nov 28.

PMID:
30484858
20.

BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes.

Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B.

Nat Commun. 2018 Nov 20;9(1):4885. doi: 10.1038/s41467-018-07193-y.

21.

Pre-treatment observation of axial elongation for evidence-based selection of children in Hong Kong for myopia control.

Cheung SW, Boost MV, Cho P.

Cont Lens Anterior Eye. 2019 Aug;42(4):392-398. doi: 10.1016/j.clae.2018.10.006. Epub 2018 Oct 24.

PMID:
30366778
22.

A new microdeletion syndrome involving TBC1D24, ATP6V0C, and PDPK1 causes epilepsy, microcephaly, and developmental delay.

Mucha BE, Banka S, Ajeawung NF, Molidperee S, Chen GG, Koenig MK, Adejumo RB, Till M, Harbord M, Perrier R, Lemyre E, Boucher RM, Skotko BG, Waxler JL, Thomas MA, Hodge JC, Gecz J, Nicholl J, McGregor L, Linden T, Sisodiya SM, Sanlaville D, Cheung SW, Ernst C, Campeau PM.

Genet Med. 2019 May;21(5):1058-1064. doi: 10.1038/s41436-018-0290-3. Epub 2018 Sep 24. Erratum in: Genet Med. 2019 Jan 14;:.

PMID:
30245510
23.

Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants.

Pizzo L, Jensen M, Polyak A, Rosenfeld JA, Mannik K, Krishnan A, McCready E, Pichon O, Le Caignec C, Van Dijck A, Pope K, Voorhoeve E, Yoon J, Stankiewicz P, Cheung SW, Pazuchanics D, Huber E, Kumar V, Kember RL, Mari F, Curró A, Castiglia L, Galesi O, Avola E, Mattina T, Fichera M, Mandarà L, Vincent M, Nizon M, Mercier S, Bénéteau C, Blesson S, Martin-Coignard D, Mosca-Boidron AL, Caberg JH, Bucan M, Zeesman S, Nowaczyk MJM, Lefebvre M, Faivre L, Callier P, Skinner C, Keren B, Perrine C, Prontera P, Marle N, Renieri A, Reymond A, Kooy RF, Isidor B, Schwartz C, Romano C, Sistermans E, Amor DJ, Andrieux J, Girirajan S.

Genet Med. 2019 Apr;21(4):816-825. doi: 10.1038/s41436-018-0266-3. Epub 2018 Sep 7.

24.

Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies.

Yuan B, Neira J, Pehlivan D, Santiago-Sim T, Song X, Rosenfeld J, Posey JE, Patel V, Jin W, Adam MP, Baple EL, Dean J, Fong CT, Hickey SE, Hudgins L, Leon E, Madan-Khetarpal S, Rawlins L, Rustad CF, Stray-Pedersen A, Tveten K, Wenger O, Diaz J, Jenkins L, Martin L, McGuire M, Pietryga M, Ramsdell L, Slattery L; DDD Study, Abid F, Bertuch AA, Grange D, Immken L, Schaaf CP, Van Esch H, Bi W, Cheung SW, Breman AM, Smith JL, Shaw C, Crosby AH, Eng C, Yang Y, Lupski JR, Xiao R, Liu P.

Genet Med. 2019 Mar;21(3):663-675. doi: 10.1038/s41436-018-0085-6. Epub 2018 Aug 30.

25.

Microarray analysis: First-trimester maternal serum free β-hCG and the risk of significant copy number variants.

Bornstein E, Gulersen M, Krantz D, Cheung SW, Maliszewski K, Divon MY.

Prenat Diagn. 2018 Nov;38(12):971-978. doi: 10.1002/pd.5350. Epub 2018 Sep 21.

PMID:
30156700
26.

Novel applications of array comparative genomic hybridization in molecular diagnostics.

Cheung SW, Bi W.

Expert Rev Mol Diagn. 2018 Jun;18(6):531-542. doi: 10.1080/14737159.2018.1479253. Epub 2018 May 31. Review.

PMID:
29848116
27.

Prenatal diagnosis of Wolf-Hirschhorn syndrome: from ultrasound findings, diagnostic technology to genetic counseling.

Xing Y, Holder JL Jr, Liu Y, Yuan M, Sun Q, Qu X, Deng L, Zhou J, Yang Y, Guo M, Cheung SW, Sun L.

Arch Gynecol Obstet. 2018 Aug;298(2):289-295. doi: 10.1007/s00404-018-4798-1. Epub 2018 May 28.

PMID:
29808250
28.

Ocular higher-order aberrations and axial eye growth in young Hong Kong children.

Lau JK, Vincent SJ, Collins MJ, Cheung SW, Cho P.

Sci Rep. 2018 Apr 30;8(1):6726. doi: 10.1038/s41598-018-24906-x.

29.

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M.

Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x.

30.

Balanced Chromosomal Rearrangement Detection by Low-Pass Whole-Genome Sequencing.

Dong Z, Ye L, Yang Z, Chen H, Yuan J, Wang H, Guo X, Li Y, Wang J, Chen F, Cheung SW, Morton CC, Jiang H, Choy KW.

Curr Protoc Hum Genet. 2018 Jan 24;96:8.18.1-8.18.16. doi: 10.1002/cphg.51.

31.

Targeted gene panel sequencing prenatally detects two novel mutations of DYNC2H1 in a fetus with increased biparietal diameter and polyhydramnios.

Deng L, Cheung SW, Schmitt ES, Xiong S, Yuan M, Chen Z, Chen L, Sun L.

Birth Defects Res. 2018 Mar 1;110(4):364-371. doi: 10.1002/bdr2.1146. Epub 2018 Jan 23.

PMID:
29359448
32.
33.

Identification of balanced chromosomal rearrangements previously unknown among participants in the 1000 Genomes Project: implications for interpretation of structural variation in genomes and the future of clinical cytogenetics.

Dong Z, Wang H, Chen H, Jiang H, Yuan J, Yang Z, Wang WJ, Xu F, Guo X, Cao Y, Zhu Z, Geng C, Cheung WC, Kwok YK, Yang H, Leung TY, Morton CC, Cheung SW, Choy KW.

Genet Med. 2018 Jul;20(7):697-707. doi: 10.1038/gim.2017.170. Epub 2017 Nov 2.

34.

Clinical Reasoning: A common cause for Phelan-McDermid syndrome and neurofibromatosis type 2: One ring to bind them.

Lyons-Warren AM, Cheung SW, Holder JL Jr.

Neurology. 2017 Oct 24;89(17):e205-e209. doi: 10.1212/WNL.0000000000004573. No abstract available.

35.

Positive predictive value estimates for cell-free noninvasive prenatal screening from data of a large referral genetic diagnostic laboratory.

Petersen AK, Cheung SW, Smith JL, Bi W, Ward PA, Peacock S, Braxton A, Van Den Veyver IB, Breman AM.

Am J Obstet Gynecol. 2017 Dec;217(6):691.e1-691.e6. doi: 10.1016/j.ajog.2017.10.005. Epub 2017 Oct 13.

36.

Does a two-year period of orthokeratology lead to changes in the endothelial morphology of children?

Cheung SW, Cho P.

Cont Lens Anterior Eye. 2018 Apr;41(2):214-218. doi: 10.1016/j.clae.2017.10.006. Epub 2017 Oct 10.

PMID:
29030016
37.

Identification of novel candidate disease genes from de novo exonic copy number variants.

Gambin T, Yuan B, Bi W, Liu P, Rosenfeld JA, Coban-Akdemir Z, Pursley AN, Nagamani SCS, Marom R, Golla S, Dengle L, Petrie HG, Matalon R, Emrick L, Proud MB, Treadwell-Deering D, Chao HT, Koillinen H, Brown C, Urraca N, Mostafavi R, Bernes S, Roeder ER, Nugent KM, Bader PI, Bellus G, Cummings M, Northrup H, Ashfaq M, Westman R, Wildin R, Beck AE, Immken L, Elton L, Varghese S, Buchanan E, Faivre L, Lefebvre M, Schaaf CP, Walkiewicz M, Yang Y, Kang SL, Lalani SR, Bacino CA, Beaudet AL, Breman AM, Smith JL, Cheung SW, Lupski JR, Patel A, Shaw CA, Stankiewicz P.

Genome Med. 2017 Sep 21;9(1):83. doi: 10.1186/s13073-017-0472-7.

38.

Surgery After Primary Radiation Treatment for Sporadic Vestibular Schwannomas: Case Series.

Breshears JD, Osorio JA, Cheung SW, Barani IJ, Theodosopoulos PV.

Oper Neurosurg (Hagerstown). 2017 Aug 1;13(4):441-447. doi: 10.1093/ons/opx023.

PMID:
28838116
39.

Erratum to: Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.

Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denommé-Pichon AS, Charif M, Besnard T, Bézieau S, Cogné B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz P.

Hum Genet. 2017 Aug;136(8):1009-1011. doi: 10.1007/s00439-017-1828-1. No abstract available.

PMID:
28660352
40.

Anisomorphic cortical reorganization in asymmetric sensorineural hearing loss.

Cheung SW, Atencio CA, Levy ERJ, Froemke RC, Schreiner CE.

J Neurophysiol. 2017 Aug 1;118(2):932-948. doi: 10.1152/jn.00119.2017. Epub 2017 May 17.

41.

Xp11.22 deletions encompassing CENPVL1, CENPVL2, MAGED1 and GSPT2 as a cause of syndromic X-linked intellectual disability.

Grau C, Starkovich M, Azamian MS, Xia F, Cheung SW, Evans P, Henderson A, Lalani SR, Scott DA.

PLoS One. 2017 Apr 17;12(4):e0175962. doi: 10.1371/journal.pone.0175962. eCollection 2017.

42.

Oral sensory dysfunction following radiotherapy.

Bearelly S, Wang SJ, Cheung SW.

Laryngoscope. 2017 Oct;127(10):2282-2286. doi: 10.1002/lary.26591. Epub 2017 Apr 11.

PMID:
28397276
43.

Protective Role of Orthokeratology in Reducing Risk of Rapid Axial Elongation: A Reanalysis of Data From the ROMIO and TO-SEE Studies.

Cho P, Cheung SW.

Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1411-1416. doi: 10.1167/iovs.16-20594.

PMID:
28253404
44.

Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.

Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denommé-Pichon AS, Charif M, Besnard T, Bézieau S, Cogné B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz P.

Hum Genet. 2017 Apr;136(4):377-386. doi: 10.1007/s00439-017-1763-1. Epub 2017 Mar 1. Erratum in: Hum Genet. 2017 Jun 28;:.

45.

Characterization of chromosomal abnormalities in pregnancy losses reveals critical genes and loci for human early development.

Chen Y, Bartanus J, Liang D, Zhu H, Breman AM, Smith JL, Wang H, Ren Z, Patel A, Stankiewicz P, Cram DS, Cheung SW, Wu L, Yu F.

Hum Mutat. 2017 Jun;38(6):669-677. doi: 10.1002/humu.23207. Epub 2017 Mar 29.

46.

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.

Liu P, Yuan B, Carvalho CMB, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, Gonzaga-Jauregui C, Wiszniewska J, Scull J, Stankiewicz P, Jhangiani SN, Muzny DM, Zhang F, Chen K, Gibbs RA, Rautenstrauss B, Cheung SW, Smith J, Breman A, Shaw CA, Patel A, Hurles ME, Lupski JR.

Cell. 2017 Feb 23;168(5):830-842.e7. doi: 10.1016/j.cell.2017.01.037.

47.

Discontinuation of orthokeratology on eyeball elongation (DOEE).

Cho P, Cheung SW.

Cont Lens Anterior Eye. 2017 Apr;40(2):82-87. doi: 10.1016/j.clae.2016.12.002. Epub 2016 Dec 27.

PMID:
28038841
48.
49.

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

St-Denis N, Gupta GD, Lin ZY, Gonzalez-Badillo B, Veri AO, Knight JDR, Rajendran D, Couzens AL, Currie KW, Tkach JM, Cheung SWT, Pelletier L, Gingras AC.

Cell Rep. 2016 Nov 22;17(9):2488-2501. doi: 10.1016/j.celrep.2016.10.078.

50.

Mechanisms for Complex Chromosomal Insertions.

Gu S, Szafranski P, Akdemir ZC, Yuan B, Cooper ML, Magriñá MA, Bacino CA, Lalani SR, Breman AM, Smith JL, Patel A, Song RH, Bi W, Cheung SW, Carvalho CM, Stankiewicz P, Lupski JR.

PLoS Genet. 2016 Nov 23;12(11):e1006446. doi: 10.1371/journal.pgen.1006446. eCollection 2016 Nov.

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