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Items: 1 to 50 of 246

1.

Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.

Chan KK, Wong ES, Wong IT, Cheung CL, Wong OG, Ngan HY, Cheung AN.

BMC Cancer. 2019 Oct 15;19(1):953. doi: 10.1186/s12885-019-6206-z.

2.

Machine learning interpretation of extended human papillomavirus genotyping by Onclarity in an Asian cervical cancer screening population.

Wong OGW, Ng IFY, Tsun OKL, Pang HH, Ip PPC, Cheung ANY.

J Clin Microbiol. 2019 Sep 11. pii: JCM.00997-19. doi: 10.1128/JCM.00997-19. [Epub ahead of print]

PMID:
31511337
3.

Placental biology of Down syndrome in relation to increased gene dosage.

Wong OGW, Ngan HYS, Cheung ANY.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):33-35. No abstract available.

4.

Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases.

Yu Y, Tse KY, Lee HHY, Chow KL, Tsang HW, Wong RWC, Cheung ETY, Cheuk W, Lee VWK, Chan WK, Wong AST, Loong HHF, Chan KKL, Ngan HYS, Cheung ANY, Ip PPC.

Mod Pathol. 2019 Aug 5. doi: 10.1038/s41379-019-0345-2. [Epub ahead of print]

PMID:
31383965
5.

ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer.

Li Z, Zhou W, Zhang Y, Sun W, Yung MMH, Sun J, Li J, Chen CW, Li Z, Meng Y, Chai J, Zhou Y, Liu SS, Cheung ANY, Ngan HYS, Chan DW, Zheng W, Zhu W.

Clin Cancer Res. 2019 Oct 1;25(19):5947-5960. doi: 10.1158/1078-0432.CCR-18-4145. Epub 2019 Jul 8.

PMID:
31285371
6.

CD71+ Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells.

Leung TH, Tang HW, Siu MK, Chan DW, Chan KK, Cheung AN, Ngan HY.

Mol Cancer Res. 2019 Sep;17(9):1867-1880. doi: 10.1158/1541-7786.MCR-19-0068. Epub 2019 Jun 24.

PMID:
31235657
7.

Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades.

Siu MKY, Jiang YX, Wang JJ, Leung THY, Han CY, Tsang BK, Cheung ANY, Ngan HYS, Chan KKL.

Cancers (Basel). 2019 Jun 12;11(6). pii: E813. doi: 10.3390/cancers11060813.

8.

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer.

Li X, Mak VCY, Zhou Y, Wang C, Wong ESY, Sharma R, Lu Y, Cheung ANY, Mills GB, Cheung LWT.

Nat Commun. 2019 Feb 12;10(1):716. doi: 10.1038/s41467-019-08574-7.

9.

Napsin A, Hepatocyte Nuclear Factor-1-Beta (HNF-1β), Estrogen and Progesterone Receptors Expression in Arias-Stella Reaction.

Ip PPC, Wang SY, Wong OGW, Chow KL, Lee HH, Cheung ANY, Tse KY.

Am J Surg Pathol. 2019 Mar;43(3):325-333. doi: 10.1097/PAS.0000000000001212.

PMID:
30608233
10.

HPV genotyping and E6/E7 transcript assays for cervical lesion detection in an Asian screening population-Cobas and Aptima HPV tests.

Wong OGW, Tsun OKL, Tsui EY, Chow JNK, Ip PPC, Cheung ANY.

J Clin Virol. 2018 Dec;109:13-18. doi: 10.1016/j.jcv.2018.10.004. Epub 2018 Oct 13.

PMID:
30368218
11.

Recommendations on prevention and screening for colorectal cancer in Hong Kong.

Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R.

Hong Kong Med J. 2018 Oct;24(5):521-526. doi: 10.12809/hkmj177095.

12.

Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer.

Liu SS, Chan KKL, Chu DKH, Wei TN, Lau LSK, Ngu SF, Chu MMY, Tse KY, Ip PPC, Ng EKO, Cheung ANY, Ngan HYS.

Mol Oncol. 2018 Dec;12(12):2009-2022. doi: 10.1002/1878-0261.12383. Epub 2018 Sep 27.

13.

miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer.

Sun J, Cai X, Yung MM, Zhou W, Li J, Zhang Y, Li Z, Liu SS, Cheung ANY, Ngan HYS, Li Y, Dai Z, Kai Y, Tzatsos A, Peng W, Chan DW, Zhu W.

Oncogene. 2019 Jan;38(4):564-580. doi: 10.1038/s41388-018-0459-x. Epub 2018 Aug 30.

PMID:
30166592
14.

Amyloid Precursor Protein Overexpression in Down Syndrome Trophoblast Reduces Cell Invasiveness and Interferes with Syncytialization.

Wong OGW, Cheung CLY, Ip PPC, Ngan HYS, Cheung ANY.

Am J Pathol. 2018 Oct;188(10):2307-2317. doi: 10.1016/j.ajpath.2018.07.004. Epub 2018 Jul 20.

PMID:
30031727
15.

Recommendations on prevention and screening for breast cancer in Hong Kong.

Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R.

Hong Kong Med J. 2018 Jun;24(3):298-306. doi: 10.12809/hkmj177037.

16.

A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors.

Tse KY, Chiu KWH, Chan KKL, Chu MMY, Ngu SF, Cheung ANY, Ngan HYS, Ip PPC.

Am J Clin Pathol. 2018 Aug 30;150(4):318-332. doi: 10.1093/ajcp/aqy039. Review.

PMID:
29897391
17.

Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface.

Tang MKS, Yue PYK, Ip PP, Huang RL, Lai HC, Cheung ANY, Tse KY, Ngan HYS, Wong AST.

Nat Commun. 2018 Jun 11;9(1):2270. doi: 10.1038/s41467-018-04695-7.

18.

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Meng Y, Chen CW, Yung MMH, Sun W, Sun J, Li Z, Li J, Li Z, Zhou W, Liu SS, Cheung ANY, Ngan HYS, Braisted JC, Kai Y, Peng W, Tzatsos A, Li Y, Dai Z, Zheng W, Chan DW, Zhu W.

Cancer Lett. 2018 Aug 1;428:104-116. doi: 10.1016/j.canlet.2018.04.029. Epub 2018 Apr 26.

PMID:
29704517
19.

Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma.

Chan KK, Wong OG, Wong ES, Chan KK, Ip PP, Tse KY, Cheung AN.

Int J Cancer. 2018 Sep 15;143(6):1456-1469. doi: 10.1002/ijc.31535. Epub 2018 May 2.

20.

Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance.

Zhou W, Sun W, Yung MMH, Dai S, Cai Y, Chen CW, Meng Y, Lee JB, Braisted JC, Xu Y, Southall NT, Shinn P, Huang X, Song Z, Chen X, Kai Y, Cai X, Li Z, Hao Q, Cheung ANY, Ngan HYS, Liu SS, Barak S, Hao J, Dai Z, Tzatsos A, Peng W, Pei H, Han Z, Chan DW, Zheng W, Zhu W.

Oncogene. 2018 Jul;37(29):3981-3997. doi: 10.1038/s41388-018-0238-8. Epub 2018 Apr 17.

21.

Identification of nonsynonymous TP53 mutations in hydatidiform moles.

Chan KK, Wong ES, Wong OG, Ngan HY, Cheung AN.

Mutat Res. 2018 May;809:20-23. doi: 10.1016/j.mrfmmm.2018.03.006. Epub 2018 Mar 29.

PMID:
29655027
22.

An automated quantitative DNA image cytometry system detects abnormal cells in cervical cytology with high sensitivity.

Wong OG, Ho MW, Tsun OK, Ng AK, Tsui EY, Chow JN, Ip PP, Cheung AN.

Cytopathology. 2018 Jun;29(3):267-274. doi: 10.1111/cyt.12540. Epub 2018 Mar 26.

PMID:
29578257
23.

Human papillomavirus E6 protein enriches the CD55(+) population in cervical cancer cells, promoting radioresistance and cancer aggressiveness.

Leung TH, Tang HW, Siu MK, Chan DW, Chan KK, Cheung AN, Ngan HY.

J Pathol. 2018 Feb;244(2):151-163. doi: 10.1002/path.4991. Epub 2017 Dec 19.

PMID:
28944962
24.

Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis.

Chan KKL, Siu MKY, Jiang YX, Wang JJ, Wang Y, Leung THY, Liu SS, Cheung ANY, Ngan HYS.

BMC Cancer. 2017 Aug 31;17(1):606. doi: 10.1186/s12885-017-3601-1.

25.

Immunoexpression of p16 in uterine leiomyomas with infarct-type necrosis: an analysis of 35 cases.

Ip PP, Lim D, Cheung ANY, Oliva E.

Histopathology. 2017 Nov;71(5):743-750. doi: 10.1111/his.13282. Epub 2017 Aug 14.

PMID:
28609585
26.

The elusive MAESTRO gene: Its human reproductive tissue-specific expression pattern.

Kenigsberg S, Lima PD, Maghen L, Wyse BA, Lackan C, Cheung AN, Tsang BK, Librach CL.

PLoS One. 2017 Apr 13;12(4):e0174873. doi: 10.1371/journal.pone.0174873. eCollection 2017.

27.

The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based study.

Chow KL, Tse KY, Cheung CL, Wong KW, Cheung AN, Wong RW, Chan AN, Yuen NW, Ngan HY, Ip PP.

Histopathology. 2017 Apr;70(5):746-755. doi: 10.1111/his.13124. Epub 2017 Jan 24.

PMID:
27864989
28.
29.

Patient compliance with cervical smear surveillance in a shared-care setting.

Tse KY, Lau SK, Lui MW, Ip PP, Cheung AN, Ngan HY.

Int J Gynaecol Obstet. 2016 Nov;135(2):177-181. doi: 10.1016/j.ijgo.2016.04.012. Epub 2016 Jul 7.

PMID:
27451399
30.

Positive predictive value of endometrial polyps in Pipelle aspiration sampling: a histopathological study of 195 cases.

Seto MT, Ip PP, Ngu SF, Cheung AN, Pun TC.

Eur J Obstet Gynecol Reprod Biol. 2016 Aug;203:12-5. doi: 10.1016/j.ejogrb.2016.04.027. Epub 2016 Apr 30.

PMID:
27219202
31.

Stem cell transcription factor NANOG in cancers--is eternal youth a curse?

Wong OG, Cheung AN.

Expert Opin Ther Targets. 2016;20(4):407-17. doi: 10.1517/14728222.2016.1112791. Epub 2015 Dec 4. Review.

PMID:
26634876
32.

Effects of adrenomedullin on the expression of inflammatory cytokines and chemokines in oviducts from women with tubal ectopic pregnancy: an in-vitro experimental study.

Li HW, Liao SB, Chiu PC, Yeung WS, Ng EH, Cheung AN, Tang F, O WS.

Reprod Biol Endocrinol. 2015 Nov 5;13:120. doi: 10.1186/s12958-015-0117-x.

33.

The Significance of Mismatch Repair Deficiency in Young Patients With Endometrial Cancer.

Chu MM, Liu SS, Tam KF, Ip PP, Cheung AN, Ngan HY.

Int J Gynecol Pathol. 2015 Sep;34(5):403-10. doi: 10.1097/PGP.0000000000000174.

PMID:
26262451
34.

p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation.

Siu MK, Kong DS, Ngai SY, Chan HY, Jiang L, Wong ES, Liu SS, Chan KK, Ngan HY, Cheung AN.

PLoS One. 2015 Jul 28;10(7):e0133467. doi: 10.1371/journal.pone.0133467. eCollection 2015.

35.

Epstein-Barr virus-positive T-cell-associated colitis mimicking inflammatory bowel disease: clinicopathological study of two cases.

Cheung FM, Tong Y, Wang Y, Cheung AN, Liu Y, Lau KK, Wong KK, Lo SK, Yuen KY.

Histopathology. 2016 Feb;68(3):465-8. doi: 10.1111/his.12773. Epub 2015 Aug 7. No abstract available.

PMID:
26156622
36.

FBI-1 Is Overexpressed in Gestational Trophoblastic Disease and Promotes Tumor Growth and Cell Aggressiveness of Choriocarcinoma via PI3K/Akt Signaling.

Mak VC, Wong OG, Siu MK, Wong ES, Ng WY, Wong RW, Chan KK, Ngan HY, Cheung AN.

Am J Pathol. 2015 Jul;185(7):2038-48. doi: 10.1016/j.ajpath.2015.03.011.

PMID:
26093985
37.

Human chorionic gonadotropin stimulates spheroid attachment on fallopian tube epithelial cells through the mitogen-activated protein kinase pathway and down-regulation of olfactomedin-1.

So KH, Kodithuwakku SP, Kottawatta KS, Li RH, Chiu PC, Cheung AN, Ng EH, Yeung WS, Lee KF.

Fertil Steril. 2015 Aug;104(2):474-82. doi: 10.1016/j.fertnstert.2015.04.030. Epub 2015 May 18.

PMID:
25999259
38.

Immunohistochemical Comparison of Ovarian and Uterine Endometrioid Carcinoma, Endometrioid Carcinoma With Clear Cell Change, and Clear Cell Carcinoma.

Lim D, Ip PP, Cheung AN, Kiyokawa T, Oliva E.

Am J Surg Pathol. 2015 Aug;39(8):1061-9. doi: 10.1097/PAS.0000000000000436.

PMID:
25871622
39.

Loss of ATRX and DAXX expression identifies poor prognosis for smooth muscle tumours of uncertain malignant potential and early stage uterine leiomyosarcoma.

Slatter TL, Hsia H, Samaranayaka A, Sykes P, Clow WB, Devenish CJ, Sutton T, Royds JA, Ip PP, Cheung AN, Hung NA.

J Pathol Clin Res. 2015 Mar 16;1(2):95-105. doi: 10.1002/cjp2.11. eCollection 2015 Apr.

40.

HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis.

Leung TW, Liu SS, Leung RC, Chu MM, Cheung AN, Ngan HY.

J Med Virol. 2015 Jun;87(6):1022-33. doi: 10.1002/jmv.24129. Epub 2015 Feb 3.

PMID:
25648229
41.

Integrated human papillomavirus analysis as an adjunct for triage of atypical cervical cytology.

Cheung AN, Wong OG, Chan KK, Yang MS, Tsang CH, Ji SL, Lo CK, Szeto E, Wong E, Ngan HY.

Hong Kong Med J. 2014 Dec;20 Suppl 6:44-7. No abstract available.

42.

Cervical cancer screening by enhanced cytology: application of novel markers.

Cheung AN, Guan XY, Ngan HY.

Hong Kong Med J. 2014 Dec;20 Suppl 6:39-43. No abstract available.

43.

Human papillomavirus status in southern Chinese women.

Liu SS, Chan KK, Leung RC, Yip AM, Lau LS, Liao XY, Jiang LL, Luk MH, Lo SS, Fong DY, Cheung AN, Lin ZQ, Ngan HY.

Hong Kong Med J. 2014 Dec;20 Suppl 6:35-8. No abstract available.

44.

Overexpression of forkhead box protein M1 (FOXM1) in ovarian cancer correlates with poor patient survival and contributes to paclitaxel resistance.

Zhao F, Siu MK, Jiang L, Tam KF, Ngan HY, Le XF, Wong OG, Wong ES, Gomes AR, Bella L, Khongkow P, Lam EW, Cheung AN.

PLoS One. 2014 Nov 20;9(11):e113478. doi: 10.1371/journal.pone.0113478. eCollection 2014.

45.

Downregulation of the gli transcription factors regulator Kif7 facilitates cell survival and migration of choriocarcinoma cells.

Ho J, Du Y, Wong OG, Siu MK, Chan KK, Cheung AN.

PLoS One. 2014 Sep 29;9(9):e108248. doi: 10.1371/journal.pone.0108248. eCollection 2014.

46.

Caution over use of ES2 as a model of ovarian clear cell carcinoma.

Kwok AL, Wong OG, Wong ES, Tsun OK, Chan KK, Cheung AN.

J Clin Pathol. 2014 Oct;67(10):921-2. doi: 10.1136/jclinpath-2014-202430. Epub 2014 Jul 21. No abstract available.

PMID:
25049276
47.

miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway.

Leung CO, Deng W, Ye TM, Ngan HY, Tsao SW, Cheung AN, Pang RT, Yeung WS.

Carcinogenesis. 2014 Sep;35(9):1931-40. doi: 10.1093/carcin/bgu032. Epub 2014 Feb 6.

PMID:
24503442
48.

Targeting estrogen-related receptor alpha inhibits epithelial-to-mesenchymal transition and stem cell properties of ovarian cancer cells.

Lam SS, Mak AS, Yam JW, Cheung AN, Ngan HY, Wong AS.

Mol Ther. 2014 Apr;22(4):743-51. doi: 10.1038/mt.2014.1. Epub 2014 Jan 14.

49.

BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis.

Tang MK, Kwong A, Tam KF, Cheung AN, Ngan HY, Xia W, Wong AS.

Cancer Lett. 2014 Apr 28;346(1):139-47. doi: 10.1016/j.canlet.2013.12.026. Epub 2013 Dec 28.

PMID:
24378767
50.

The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells.

Leung TH, Wong SC, Chan KK, Chan DW, Cheung AN, Ngan HY.

Br J Cancer. 2013 Aug 20;109(4):965-75. doi: 10.1038/bjc.2013.397. Epub 2013 Jul 23.

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