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Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70-Positive Tumors for Multimodal Cancer Theranostics.

Shevtsov M, Stangl S, Nikolaev B, Yakovleva L, Marchenko Y, Tagaeva R, Sievert W, Pitkin E, Mazur A, Tolstoy P, Galibin O, Ryzhov V, Steiger K, Smirnov O, Khachatryan W, Chester K, Multhoff G.

Small. 2019 Mar;15(13):e1900205. doi: 10.1002/smll.201900205. Epub 2019 Mar 4.


Making a case for the right '-ase' in acute ischemic stroke: alteplase, tenecteplase, and reteplase.

Chester KW, Corrigan M, Schoeffler JM, Shah M, Toy F, Purdon B, Dillon GM.

Expert Opin Drug Saf. 2019 Feb;18(2):87-96. doi: 10.1080/14740338.2019.1573985. Review.


The use of a surface active agent in the protection of a fusion protein during bioprocessing.

Blas P, Tolner B, Ward J, Chester K, Hoare M.

Biotechnol Bioeng. 2018 Nov;115(11):2760-2770. doi: 10.1002/bit.26817. Epub 2018 Sep 8.


Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.

Lechner M, Chakravarthy AR, Walter V, Masterson L, Feber A, Jay A, Weinberger PM, McIndoe RA, Forde CT, Chester K, Kalavrezos N, O'Flynn P, Forster M, Jones TM, Vaz FM, Hayes DN, Fenton TR.

Oral Oncol. 2018 Aug;83:32-37. doi: 10.1016/j.oraloncology.2018.06.006. Epub 2018 Jun 9.


Synonym-Based Word Frequency Analysis to Support the Development and Presentation of a Public Health Quality Improvement Taxonomy.

Pina J, Massoudi BL, Chester K, Koyanagi M.

J Public Health Manag Pract. 2019 Jan/Feb;25(1):81-85. doi: 10.1097/PHH.0000000000000805.


Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs.

Forte N, Livanos M, Miranda E, Morais M, Yang X, Rajkumar VS, Chester KA, Chudasama V, Baker JR.

Bioconjug Chem. 2018 Feb 21;29(2):486-492. doi: 10.1021/acs.bioconjchem.7b00795. Epub 2018 Jan 31.


Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles.

Abdollah MRA, Carter TJ, Jones C, Kalber TL, Rajkumar V, Tolner B, Gruettner C, Zaw-Thin M, Baguña Torres J, Ellis M, Robson M, Pedley RB, Mulholland P, T M de Rosales R, Chester KA.

ACS Nano. 2018 Feb 27;12(2):1156-1169. doi: 10.1021/acsnano.7b06734. Epub 2018 Jan 17.


Risk of Hypoglycemia During Insulin Infusion Directed by Paper Protocol Versus Electronic Glycemic Management System in Critically Ill Patients at a Large Academic Medical Center.

Rabinovich M, Grahl J, Durr E, Gayed R, Chester K, McFarland R, McLean B.

J Diabetes Sci Technol. 2018 Jan;12(1):47-52. doi: 10.1177/1932296817747617. Epub 2017 Dec 17.


Public Health, Population Health, and Epidemiology Informatics: Recent Research and Trends in the United States.

Massoudi BL, Chester KG.

Yearb Med Inform. 2017 Aug;26(1):241-247. doi: 10.15265/IY-2017-035. Epub 2017 Sep 11. Review.


Association Between Experiencing Relational Bullying and Adolescent Health-Related Quality of Life.

Chester KL, Spencer NH, Whiting L, Brooks FM.

J Sch Health. 2017 Nov;87(11):865-872. doi: 10.1111/josh.12558.


Hypoglycemic Potential of Aqueous Extract of Moringa oleifera Leaf and In Vivo GC-MS Metabolomics.

Khan W, Parveen R, Chester K, Parveen S, Ahmad S.

Front Pharmacol. 2017 Sep 12;8:577. doi: 10.3389/fphar.2017.00577. eCollection 2017.


UPLC-ESI-MS/MS and HPTLC Method for Quantitative Estimation of Cytotoxic Glycosides and Aglycone in Bioactivity Guided Fractions of Solanum nigrum L.

Chester K, Paliwal S, Khan W, Ahmad S.

Front Pharmacol. 2017 Jul 6;8:434. doi: 10.3389/fphar.2017.00434. eCollection 2017.


The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.

Thistlethwaite FC, Gilham DE, Guest RD, Rothwell DG, Pillai M, Burt DJ, Byatte AJ, Kirillova N, Valle JW, Sharma SK, Chester KA, Westwood NB, Halford SER, Nabarro S, Wan S, Austin E, Hawkins RE.

Cancer Immunol Immunother. 2017 Nov;66(11):1425-1436. doi: 10.1007/s00262-017-2034-7. Epub 2017 Jun 28.


'Part of me already knew': the experiences of partners of people going through a gender transition process.

Chester K, Lyons A, Hopner V.

Cult Health Sex. 2017 Dec;19(12):1404-1417. doi: 10.1080/13691058.2017.1317109. Epub 2017 May 2.


Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

Arce Vargas F, Furness AJS, Solomon I, Joshi K, Mekkaoui L, Lesko MH, Miranda Rota E, Dahan R, Georgiou A, Sledzinska A, Ben Aissa A, Franz D, Werner Sunderland M, Wong YNS, Henry JY, O'Brien T, Nicol D, Challacombe B, Beers SA; Melanoma TRACERx Consortium; Renal TRACERx Consortium; Lung TRACERx Consortium, Turajlic S, Gore M, Larkin J, Swanton C, Chester KA, Pule M, Ravetch JV, Marafioti T, Peggs KS, Quezada SA.

Immunity. 2017 Apr 18;46(4):577-586. doi: 10.1016/j.immuni.2017.03.013. Epub 2017 Apr 11.


Use of sonic tomography to detect and quantify wood decay in living trees.

Gilbert GS, Ballesteros JO, Barrios-Rodriguez CA, Bonadies EF, Cedeño-Sánchez ML, Fossatti-Caballero NJ, Trejos-Rodríguez MM, Pérez-Suñiga JM, Holub-Young KS, Henn LA, Thompson JB, García-López CG, Romo AC, Johnston DC, Barrick PP, Jordan FA, Hershcovich S, Russo N, Sánchez JD, Fábrega JP, Lumpkin R, McWilliams HA, Chester KN, Burgos AC, Wong EB, Diab JH, Renteria SA, Harrower JT, Hooton DA, Glenn TC, Faircloth BC, Hubbell SP.

Appl Plant Sci. 2016 Dec 16;4(12). pii: apps.1600060. doi: 10.3732/apps.1600060. eCollection 2016 Dec.


Experience of Primary Care Services Among Early Adolescents in England and Association With Health Outcomes.

Yassaee AA, Hargreaves DS, Chester K, Lamb S, Hagell A, Brooks FM.

J Adolesc Health. 2017 Apr;60(4):388-394. doi: 10.1016/j.jadohealth.2016.09.022. Epub 2016 Dec 1.


Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients with Sepsis.

Rahbar AJ, Lodise TP, Abraham P, Lockwood A, Pai MP, Patka J, Rabinovich M, Curzio K, Chester K, Williams B, Morse B, Chaar M, Huang V, Salomone J.

Surg Infect (Larchmt). 2016 Dec;17(6):675-682. Epub 2016 Nov 14.


Antibody Engineering & Therapeutics 2016: The Antibody Society's annual meeting, December 11-15, 2016, San Diego, CA.

Larrick JW, Alfenito MR, Scott JK, Parren PW, Burton DR, Bradbury AR, Lemere CA, Messer A, Huston JS, Carter PJ, Veldman T, Chester KA, Schuurman J, Adams GP, Reichert JM.

MAbs. 2016 Nov/Dec;8(8):1425-1434. Epub 2016 Aug 24.


Public Health Staff Development Needs in Informatics: Findings From a National Survey of Local Health Departments.

Massoudi BL, Chester K, Shah GH.

J Public Health Manag Pract. 2016 Nov-Dec;22 Suppl 6, Public Health Informatics:S58-S62.


Control of the Public Health IT Physical Infrastructure: Findings From the 2015 Informatics Capacity and Needs Assessment Survey.

Chester K, Massoudi BL, Shah GH.

J Public Health Manag Pract. 2016 Nov-Dec;22 Suppl 6, Public Health Informatics:S13-S17.


Self-harm in adolescence: protective health assets in the family, school and community.

Klemera E, Brooks FM, Chester KL, Magnusson J, Spencer N.

Int J Public Health. 2017 Jul;62(6):631-638. doi: 10.1007/s00038-016-0900-2. Epub 2016 Sep 22.


Antibody-targeted nanoparticles for cancer treatment.

Carter T, Mulholland P, Chester K.

Immunotherapy. 2016 Jul;8(8):941-58. doi: 10.2217/imt.16.11. Review. Erratum in: Immunotherapy. 2016 Sep;8(9):1151.


Ipilimumab and Bevacizumab in Glioblastoma.

Carter T, Shaw H, Cohn-Brown D, Chester K, Mulholland P.

Clin Oncol (R Coll Radiol). 2016 Oct;28(10):622-6. doi: 10.1016/j.clon.2016.04.042. Epub 2016 May 8.


The INNs and outs of antibody nonproprietary names.

Jones TD, Carter PJ, Plückthun A, Vásquez M, Holgate RG, Hötzel I, Popplewell AG, Parren PW, Enzelberger M, Rademaker HJ, Clark MR, Lowe DC, Dahiyat BI, Smith V, Lambert JM, Wu H, Reilly M, Haurum JS, Dübel S, Huston JS, Schirrmann T, Janssen RA, Steegmaier M, Gross JA, Bradbury AR, Burton DR, Dimitrov DS, Chester KA, Glennie MJ, Davies J, Walker A, Martin S, McCafferty J, Baker MP.

MAbs. 2016;8(1):1-9. doi: 10.1080/19420862.2015.1114320.


Characterization of Linum usitatissimum L. oil obtained from different extraction technique and in vitro antioxidant potential of supercritical fluid extract.

Chauhan R, Chester K, Khan Y, Tamboli ET, Ahmad S.

J Pharm Bioallied Sci. 2015 Oct-Dec;7(4):284-8. doi: 10.4103/0975-7406.168027.


Quality control aspects of herbs and botanicals in developing countries: Coleus forskohlii Briq a case study.

Tamboli ET, Chester K, Ahmad S.

J Pharm Bioallied Sci. 2015 Oct-Dec;7(4):254-9. doi: 10.4103/0975-7406.168020.


Antibody Engineering & Therapeutics 2015: The Antibody Society's annual meeting December 7-10, 2015, San Diego, CA.

Parren PW, Burton DR, Bradbury A, Huston JS, Carter PJ, Veldman T, Chester KA, Larrick JW, Alfenito MR, Scott JK, Weiner LM, Adams GP, Reichert JM.

MAbs. 2015;7(6):981-8. doi: 10.1080/19420862.2015.1089707. Epub 2015 Sep 30.


IMAC capture of recombinant protein from unclarified mammalian cell feed streams.

Kinna A, Tolner B, Rota EM, Titchener-Hooker N, Nesbeth D, Chester K.

Biotechnol Bioeng. 2016 Jan;113(1):130-40. doi: 10.1002/bit.25705. Epub 2015 Sep 3.


Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors.

Boonstra MC, Tolner B, Schaafsma BE, Boogerd LS, Prevoo HA, Bhavsar G, Kuppen PJ, Sier CF, Bonsing BA, Frangioni JV, van de Velde CJ, Chester KA, Vahrmeijer AL.

Int J Cancer. 2015 Oct 15;137(8):1910-20. doi: 10.1002/ijc.29571. Epub 2015 Jun 22.


A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.

Maruani A, Smith ME, Miranda E, Chester KA, Chudasama V, Caddick S.

Nat Commun. 2015 Mar 31;6:6645. doi: 10.1038/ncomms7645.


Cross-national time trends in bullying victimization in 33 countries among children aged 11, 13 and 15 from 2002 to 2010.

Chester KL, Callaghan M, Cosma A, Donnelly P, Craig W, Walsh S, Molcho M.

Eur J Public Health. 2015 Apr;25 Suppl 2:61-4. doi: 10.1093/eurpub/ckv029.


Magnetic nanoparticles: general discussion.

Dobson P, Yung LL, Rossi L, Carreira S, Ray P, Amiens C, Brown K, Zhou D, Gavriilidis A, Thanh NT, Moise S, Litti L, Mattoussi H, Todd M, Mitchell S, Borsley S, Heuer-Jungemann A, Reiser O, Tsang E, Thanou M, Berkleman T, Soukup D, Chester K, Parkin I, Diaz Fernandez YA, Burke BP.

Faraday Discuss. 2014;175:113-35. doi: 10.1039/C4FD90078B. No abstract available.


Antibody engineering and therapeutics conference. The annual meeting of the antibody society, Huntington Beach, CA, December 7-11, 2014.

Larrick JW, Parren P, Huston JS, Plückthun A, Bradbury A, Tomlinson IM, Chester KA, Burton DR, Adams GP, Weiner LM, Scott JK, Alfenito MR, Veldman T, Reichert JM.

MAbs. 2014;6(5):1115-23. doi: 10.4161/19420862.2014.971627.


Is there a link between overactive bladder and the metabolic syndrome in women? A systematic review of observational studies.

Bunn F, Kirby M, Pinkney E, Cardozo L, Chapple C, Chester K, Cruz F, Haab F, Kelleher C, Milsom I, Sievart KD, Tubaro A, Wagg A.

Int J Clin Pract. 2015 Feb;69(2):199-217. doi: 10.1111/ijcp.12518. Epub 2014 Dec 11. Review.


Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.

Goldstein R, Sosabowski J, Livanos M, Leyton J, Vigor K, Bhavsar G, Nagy-Davidescu G, Rashid M, Miranda E, Yeung J, Tolner B, Plückthun A, Mather S, Meyer T, Chester K.

Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):288-301. doi: 10.1007/s00259-014-2940-2. Epub 2014 Nov 13.


Comparative evaluation of ziehl neelsen staining and knowledge, attitudes and practices of laboratory personnel in relation to ziehl nielsen.

Kurup R, Chester K.

West Indian Med J. 2014 Jan;63(1):34-9. doi: 10.7727/wimj.2012.247. Epub 2014 Apr 8.


Prolonging the circulatory retention of SPIONs using dextran sulfate: in vivo tracking achieved by functionalisation with near-infrared dyes.

Abdollah MR, Kalber T, Tolner B, Southern P, Bear JC, Robson M, Pedley RB, Parkin IP, Pankhurst QA, Mulholland P, Chester K.

Faraday Discuss. 2014;175:41-58. doi: 10.1039/c4fd00114a.


Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.

Schumacher FF, Nunes JP, Maruani A, Chudasama V, Smith ME, Chester KA, Baker JR, Caddick S.

Org Biomol Chem. 2014 Oct 7;12(37):7261-9. doi: 10.1039/c4ob01550a.


Homogeneous bispecifics by disulfide bridging.

Hull EA, Livanos M, Miranda E, Smith ME, Chester KA, Baker JR.

Bioconjug Chem. 2014 Aug 20;25(8):1395-401. doi: 10.1021/bc5002467. Epub 2014 Aug 1.


Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds.

Marculescu C, Kossen H, Morgan RE, Mayer P, Fletcher SA, Tolner B, Chester KA, Jones LH, Baker JR.

Chem Commun (Camb). 2014 Jul 11;50(54):7139-42. doi: 10.1039/c4cc02107j.


Beacon communities' public health initiatives: a case study analysis.

Massoudi BL, Marcial LH, Haque S, Bailey R, Chester K, Cunningham S, Riley A, Soper P.

EGEMS (Wash DC). 2014 Oct 24;2(3):1093. doi: 10.13063/2327-9214.1093. eCollection 2014.


Generation and characterization of a diabody targeting the αvβ6 integrin.

Kogelberg H, Miranda E, Burnet J, Ellison D, Tolner B, Foster J, Picón C, Thomas GJ, Meyer T, Marshall JF, Mather SJ, Chester K.

PLoS One. 2013 Sep 4;8(9):e73260. doi: 10.1371/journal.pone.0073260. eCollection 2013.


Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.

Castañeda L, Maruani A, Schumacher FF, Miranda E, Chudasama V, Chester KA, Baker JR, Smith ME, Caddick S.

Chem Commun (Camb). 2013 Sep 25;49(74):8187-9. doi: 10.1039/c3cc45220d.


A review of current agents for anticoagulation for the critical care practitioner.

Abraham P, Rabinovich M, Curzio K, Patka J, Chester K, Holt T, Goddard K, Feliciano DV.

J Crit Care. 2013 Oct;28(5):763-74. doi: 10.1016/j.jcrc.2013.06.013. Epub 2013 Jul 20. Review.


Genetic and metabolic diversity in Stevia rebaudiana using RAPD and HPTLC analysis.

Chester K, Tamboli ET, Parveen R, Ahmad S.

Pharm Biol. 2013 Jun;51(6):771-7. doi: 10.3109/13880209.2013.765898. Epub 2013 Apr 11.


Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.

Schumacher FF, Sanchania VA, Tolner B, Wright ZV, Ryan CP, Smith ME, Ward JM, Caddick S, Kay CW, Aeppli G, Chester KA, Baker JR.

Sci Rep. 2013;3:1525. doi: 10.1038/srep01525.


Developments in single photon emission computed tomography and PET-based HER2 molecular imaging for breast cancer.

Goldstein R, Sosabowski J, Vigor K, Chester K, Meyer T.

Expert Rev Anticancer Ther. 2013 Mar;13(3):359-73. doi: 10.1586/era.13.11. Review.


Simultaneous quantification of stevioside and rebaudioside A in different stevia samples collected from the Indian subcontinent.

Chester K, Tamboli ET, Singh M, Ahmad S.

J Pharm Bioallied Sci. 2012 Oct;4(4):276-81. doi: 10.4103/0975-7406.103236.

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