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Items: 7

1.

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma.

Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031369. doi: 10.1242/dmm.031369.

2.

Light and Electron Microscopy Methods for Examination of Cochlear Morphology in Mouse Models of Deafness.

Parker A, Chessum L, Mburu P, Sanderson J, Bowl MR.

Curr Protoc Mouse Biol. 2016 Sep 1;6(3):272-306. doi: 10.1002/cpmo.10.

PMID:
27584554
3.

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD.

Nat Commun. 2016 Aug 18;7:12444. doi: 10.1038/ncomms12444.

4.

Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair.

Mianné J, Chessum L, Kumar S, Aguilar C, Codner G, Hutchison M, Parker A, Mallon AM, Wells S, Simon MM, Teboul L, Brown SD, Bowl MR.

Genome Med. 2016 Feb 15;8(1):16. doi: 10.1186/s13073-016-0273-4.

5.

Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss.

Carrott L, Bowl MR, Aguilar C, Johnson SL, Chessum L, West M, Morse S, Dorning J, Smart E, Hardisty-Hughes R, Ball G, Parker A, Barnard AR, MacLaren RE, Wells S, Marcotti W, Brown SD.

J Neurosci. 2016 Jan 6;36(1):222-34. doi: 10.1523/JNEUROSCI.1808-15.2016.

6.

Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.

Zhang Y, Dean C, Chessum L, Nguyen D, Stewart M, Taylor M, Cookson WO, Moffatt MF.

Mamm Genome. 2014 Dec;25(11-12):573-82. doi: 10.1007/s00335-014-9535-x. Epub 2014 Aug 5.

7.

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH.

Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27.

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