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Items: 1 to 50 of 118

1.

Systems genetics of sensation seeking.

Dickson PE, Roy TA, McNaughton KA, Wilcox TD, Kumar P, Chesler EJ.

Genes Brain Behav. 2018 Sep 17:e12519. doi: 10.1111/gbb.12519. [Epub ahead of print]

PMID:
30221471
2.

Genome-wide association for testis weight in the diversity outbred mouse population.

Yuan JT, Gatti DM, Philip VM, Kasparek S, Kreuzman AM, Mansky B, Sharif K, Taterra D, Taylor WM, Thomas M, Ward JO, Holmes A, Chesler EJ, Parker CC.

Mamm Genome. 2018 Jun;29(5-6):310-324. doi: 10.1007/s00335-018-9745-8. Epub 2018 Apr 24.

PMID:
29691636
3.

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling.

Cobos EJ, Nickerson CA, Gao F, Chandran V, Bravo-Caparrós I, González-Cano R, Riva P, Andrews NA, Latremoliere A, Seehus CR, Perazzoli G, Nieto FR, Joller N, Painter MW, Ma CHE, Omura T, Chesler EJ, Geschwind DH, Coppola G, Rangachari M, Woolf CJ, Costigan M.

Cell Rep. 2018 Jan 30;22(5):1301-1312. doi: 10.1016/j.celrep.2018.01.006.

4.

Reproducibility and replicability of rodent phenotyping in preclinical studies.

Kafkafi N, Agassi J, Chesler EJ, Crabbe JC, Crusio WE, Eilam D, Gerlai R, Golani I, Gomez-Marin A, Heller R, Iraqi F, Jaljuli I, Karp NA, Morgan H, Nicholson G, Pfaff DW, Richter SH, Stark PB, Stiedl O, Stodden V, Tarantino LM, Tucci V, Valdar W, Williams RW, Würbel H, Benjamini Y.

Neurosci Biobehav Rev. 2018 Apr;87:218-232. doi: 10.1016/j.neubiorev.2018.01.003. Epub 2018 Jan 31. Review.

5.

Identification of a novel gene regulating amygdala-mediated fear extinction.

Gunduz-Cinar O, Brockway E, Lederle L, Wilcox T, Halladay LR, Ding Y, Oh H, Busch EF, Kaugars K, Flynn S, Limoges A, Bukalo O, MacPherson KP, Masneuf S, Pinard C, Sibille E, Chesler EJ, Holmes A.

Mol Psychiatry. 2018 Jan 8. doi: 10.1038/s41380-017-0003-3. [Epub ahead of print]

6.

Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice.

Bogue MA, Grubb SC, Walton DO, Philip VM, Kolishovski G, Stearns T, Dunn MH, Skelly DA, Kadakkuzha B, TeHennepe G, Kunde-Ramamoorthy G, Chesler EJ.

Nucleic Acids Res. 2018 Jan 4;46(D1):D843-D850. doi: 10.1093/nar/gkx1082.

7.

Prevalence of sexual dimorphism in mammalian phenotypic traits.

Karp NA, Mason J, Beaudet AL, Benjamini Y, Bower L, Braun RE, Brown SDM, Chesler EJ, Dickinson ME, Flenniken AM, Fuchs H, Angelis MH, Gao X, Guo S, Greenaway S, Heller R, Herault Y, Justice MJ, Kurbatova N, Lelliott CJ, Lloyd KCK, Mallon AM, Mank JE, Masuya H, McKerlie C, Meehan TF, Mott RF, Murray SA, Parkinson H, Ramirez-Solis R, Santos L, Seavitt JR, Smedley D, Sorg T, Speak AO, Steel KP, Svenson KL; International Mouse Phenotyping Consortium, Wakana S, West D, Wells S, Westerberg H, Yaacoby S, White JK.

Nat Commun. 2017 Jun 26;8:15475. doi: 10.1038/ncomms15475.

8.

Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross.

Shorter JR, Odet F, Aylor DL, Pan W, Kao CY, Fu CP, Morgan AP, Greenstein S, Bell TA, Stevans AM, Feathers RW, Patel S, Cates SE, Shaw GD, Miller DR, Chesler EJ, McMillian L, O'Brien DA, Villena FP.

Genetics. 2017 Jun;206(2):557-572. doi: 10.1534/genetics.116.199596.

9.

QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field.

Delprato A, Algéo MP, Bonheur B, Bubier JA, Lu L, Williams RW, Chesler EJ, Crusio WE.

Genes Brain Behav. 2017 Nov;16(8):790-799. doi: 10.1111/gbb.12392. Epub 2017 Jun 22.

PMID:
28544613
10.

Systems Genetic Analysis in GeneNetwork.org.

Parker CC, Dickson PE, Philip VM, Thomas M, Chesler EJ.

Curr Protoc Neurosci. 2017 Apr 10;79:8.39.1-8.39.20. doi: 10.1002/cpns.23.

11.

Integrative Functional Genomics for Systems Genetics in GeneWeaver.org.

Bubier JA, Langston MA, Baker EJ, Chesler EJ.

Methods Mol Biol. 2017;1488:131-152.

PMID:
27933523
12.

Analysis of morphine responses in mice reveals a QTL on Chromosome 7.

Crusio WE, Dhawan E, Chesler EJ, Delprato A.

Version 2. F1000Res. 2016 Sep 2 [revised 2016 Jan 1];5:2156. eCollection 2016.

13.

Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption.

McGuier NS, Griffin WC 3rd, Gass JT, Padula AE, Chesler EJ, Mulholland PJ.

Addict Biol. 2016 Nov;21(6):1097-1112. doi: 10.1111/adb.12279. Epub 2015 Jun 23.

14.

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection.

Chesler EJ, Gatti DM, Morgan AP, Strobel M, Trepanier L, Oberbeck D, McWeeney S, Hitzemann R, Ferris M, McMullan R, Clayshultle A, Bell TA, Manuel de Villena FP, Churchill GA.

G3 (Bethesda). 2016 Dec 7;6(12):3893-3902. doi: 10.1534/g3.116.035527.

15.

Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test.

Young EE, Bryant CD, Lee SE, Peng X, Cook B, Nair HK, Dreher KJ, Zhang X, Palmer AA, Chung JM, Mogil JS, Chesler EJ, Lariviere WR.

Genes Brain Behav. 2016 Jul;15(6):604-15. doi: 10.1111/gbb.12302.

16.

Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains.

Putman AH, Wolen AR, Harenza JL, Yordanova RK, Webb BT, Chesler EJ, Miles MF.

Genes Brain Behav. 2016 Apr;15(4):367-81. doi: 10.1111/gbb.12289.

17.

R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.

18.

Cross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol.

Bubier JA, Wilcox TD, Jay JJ, Langston MA, Baker EJ, Chesler EJ.

Front Behav Neurosci. 2016 Jan 21;10:1. doi: 10.3389/fnbeh.2016.00001. eCollection 2016.

19.

GeneWeaver: data driven alignment of cross-species genomics in biology and disease.

Baker E, Bubier JA, Reynolds T, Langston MA, Chesler EJ.

Nucleic Acids Res. 2016 Jan 4;44(D1):D555-9. doi: 10.1093/nar/gkv1329. Epub 2015 Dec 9.

20.

Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel.

Dickson PE, Miller MM, Calton MA, Bubier JA, Cook MN, Goldowitz D, Chesler EJ, Mittleman G.

Psychopharmacology (Berl). 2016 Feb;233(4):701-14. doi: 10.1007/s00213-015-4147-z. Epub 2015 Nov 19.

21.

Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population.

Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN.

BMC Genomics. 2015 Aug 25;16:633. doi: 10.1186/s12864-015-1732-9.

22.

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database.

Bogue MA, Churchill GA, Chesler EJ.

Mamm Genome. 2015 Oct;26(9-10):511-20. doi: 10.1007/s00335-015-9595-6. Epub 2015 Aug 19.

23.

Sex and strain influence attribution of incentive salience to reward cues in mice.

Dickson PE, McNaughton KA, Hou L, Anderson LC, Long KH, Chesler EJ.

Behav Brain Res. 2015 Oct 1;292:305-15. doi: 10.1016/j.bbr.2015.05.039. Epub 2015 Jun 20.

24.

GeneWeaver: finding consilience in heterogeneous cross-species functional genomics data.

Bubier JA, Phillips CA, Langston MA, Baker EJ, Chesler EJ.

Mamm Genome. 2015 Oct;26(9-10):556-66. doi: 10.1007/s00335-015-9575-x. Epub 2015 Jun 20.

25.

Aging Research Using Mouse Models.

Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL.

Curr Protoc Mouse Biol. 2015 Jun 1;5(2):95-133. doi: 10.1002/9780470942390.mo140195.

26.

Applying the ARRIVE Guidelines to an In Vivo Database.

Karp NA, Meehan TF, Morgan H, Mason JC, Blake A, Kurbatova N, Smedley D, Jacobsen J, Mott RF, Iyer V, Matthews P, Melvin DG, Wells S, Flenniken AM, Masuya H, Wakana S, White JK, Lloyd KC, Reynolds CL, Paylor R, West DB, Svenson KL, Chesler EJ, de Angelis MH, Tocchini-Valentini GP, Sorg T, Herault Y, Parkinson H, Mallon AM, Brown SD.

PLoS Biol. 2015 May 20;13(5):e1002151. doi: 10.1371/journal.pbio.1002151. eCollection 2015 May.

27.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.

28.

KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.

Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.

Neuropsychopharmacology. 2015 Jul;40(8):1928-39. doi: 10.1038/npp.2015.42. Epub 2015 Feb 9.

29.

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.

Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ.

J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):170-7. doi: 10.1093/gerona/glu223. Epub 2014 Dec 22.

30.

Identifying common components across biological network graphs using a bipartite data model.

Baker E, Culpepper C, Philips C, Bubier J, Langston M, Chesler E.

BMC Proc. 2014 Oct 13;8(Suppl 6 Proceedings of the Great Lakes Bioinformatics Confer):S4. doi: 10.1186/1753-6561-8-S6-S4. eCollection 2014.

31.

Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice.

Dickson PE, Ndukum J, Wilcox T, Clark J, Roy B, Zhang L, Li Y, Lin DT, Chesler EJ.

Psychopharmacology (Berl). 2015 Mar;232(6):1011-24. doi: 10.1007/s00213-014-3737-5. Epub 2014 Sep 20.

32.

Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.

33.

RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.

Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA.

Genetics. 2014 Sep;198(1):59-73. doi: 10.1534/genetics.114.165886.

34.

Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung.

Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN.

Genetics. 2014 Oct;198(2):735-45. doi: 10.1534/genetics.114.168138. Epub 2014 Aug 11.

35.

Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.

Bubier JA, Jay JJ, Baker CL, Bergeson SE, Ohno H, Metten P, Crabbe JC, Chesler EJ.

Genetics. 2014 Aug;197(4):1377-93. doi: 10.1534/genetics.114.166165. Epub 2014 Jun 11.

36.

On finding bicliques in bipartite graphs: a novel algorithm and its application to the integration of diverse biological data types.

Zhang Y, Phillips CA, Rogers GL, Baker EJ, Chesler EJ, Langston MA.

BMC Bioinformatics. 2014 Apr 15;15:110. doi: 10.1186/1471-2105-15-110.

37.

Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene.

Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Mamm Genome. 2014 Jun;25(5-6):211-22. doi: 10.1007/s00335-014-9508-0. Epub 2014 Apr 5.

38.

Integrative genetic analysis of allergic inflammation in the murine lung.

Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):436-45. doi: 10.1165/rcmb.2013-0501OC.

39.

High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline.

Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F.

Genetics. 2014 May;197(1):91-106. doi: 10.1534/genetics.114.161653. Epub 2014 Feb 27.

40.

Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research.

Chesler EJ.

Mamm Genome. 2014 Feb;25(1-2):3-11. doi: 10.1007/s00335-013-9492-9. Epub 2013 Nov 23. Review.

41.

Performing integrative functional genomics analysis in GeneWeaver.org.

Jay JJ, Chesler EJ.

Methods Mol Biol. 2014;1101:13-29. doi: 10.1007/978-1-62703-721-1_2.

PMID:
24233775
42.

High-precision genetic mapping of behavioral traits in the diversity outbred mouse population.

Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ.

Genes Brain Behav. 2013 Jun;12(4):424-37. doi: 10.1111/gbb.12029. Epub 2013 Mar 20.

43.

Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination.

DuBose CS, Chesler EJ, Goldowitz D, Hamre KM.

Alcohol Clin Exp Res. 2013 Jan;37(1):170-83. doi: 10.1111/j.1530-0277.2012.01865.x.

PMID:
23289978
44.

Opportunities for bioinformatics in the classification of behavior and psychiatric disorders.

Chesler EJ, Logan RW.

Int Rev Neurobiol. 2012;104:183-211. doi: 10.1016/B978-0-12-398323-7.00008-2.

PMID:
23195316
45.

The field of bioinformatics. Preface.

Chesler EJ, Haendel MA.

Int Rev Neurobiol. 2012;103:xi-xii. doi: 10.1016/B978-0-12-388408-4.09986-X. No abstract available.

PMID:
23195125
46.

Lost and found in behavioral informatics.

Haendel MA, Chesler EJ.

Int Rev Neurobiol. 2012;103:1-18. doi: 10.1016/B978-0-12-388408-4.00001-0. Review.

PMID:
23195118
47.

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains.

Parsons MJ, Grimm C, Paya-Cano JL, Fernandes C, Liu L, Philip VM, Chesler EJ, Nietfeld W, Lehrach H, Schalkwyk LC.

BMC Genomics. 2012 Sep 13;13:476. doi: 10.1186/1471-2164-13-476.

48.

Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations.

Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo K.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F972-81. doi: 10.1152/ajprenal.00690.2011. Epub 2012 Aug 1.

49.

Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum.

Ha TJ, Swanson DJ, Kirova R, Yeung J, Choi K, Tong Y, Chesler EJ, Goldowitz D.

Eur J Neurosci. 2012 Oct;36(7):2888-98. doi: 10.1111/j.1460-9568.2012.08221.x. Epub 2012 Jul 22.

50.

A systematic comparison of genome-scale clustering algorithms.

Jay JJ, Eblen JD, Zhang Y, Benson M, Perkins AD, Saxton AM, Voy BH, Chesler EJ, Langston MA.

BMC Bioinformatics. 2012 Jun 25;13 Suppl 10:S7. doi: 10.1186/1471-2105-13-S10-S7.

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