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Items: 1 to 50 of 146


A multiomics approach to heterogeneity in Alzheimer's disease: focused review and roadmap.

Badhwar A, McFall GP, Sapkota S, Black SE, Chertkow H, Duchesne S, Masellis M, Li L, Dixon RA, Bellec P.

Brain. 2019 Dec 31. pii: awz384. doi: 10.1093/brain/awz384. [Epub ahead of print]


Are large simple trials for dementia prevention possible?

Whiteley WN, Anand S, Bangdiwala SI, Bosch J, Canavan M, Chertkow H, Gerstein HC, Gorelick P, O'Donnell M, Paré G, Pigeyre M, Seshadri S, Sharma M, Smith EE, Williamson J, Cukierman-Yaffe T, Hart RG, Yusuf S.

Age Ageing. 2019 Dec 12. pii: afz152. doi: 10.1093/ageing/afz152. [Epub ahead of print]


Maximizing the Treatment Benefit of tDCS in Neurodegenerative Anomia.

Roncero C, Service E, De Caro M, Popov A, Thiel A, Probst S, Chertkow H.

Front Neurosci. 2019 Nov 22;13:1231. doi: 10.3389/fnins.2019.01231. eCollection 2019.


Amyloid burden and white matter hyperintensities mediate age-related cognitive differences.

Dupont PS, Bocti C, Joannette M, Lavallée MM, Nikelski J, Vallet GT, Chertkow H, Joubert S.

Neurobiol Aging. 2019 Aug 31. pii: S0197-4580(19)30304-5. doi: 10.1016/j.neurobiolaging.2019.08.025. [Epub ahead of print]


Education as a moderator of the relationship between episodic memory and amyloid load in normal aging.

Joannette M, Bocti C, Dupont PS, Lavallée MM, Nikelski J, Vallet GT, Chertkow H, Joubert S.

J Gerontol A Biol Sci Med Sci. 2019 Oct 23. pii: glz235. doi: 10.1093/gerona/glz235. [Epub ahead of print]


Investigation into the effect of transcranial direct current stimulation on cardiac pacemakers.

Roncero C, Mardigyan V, Service E, Singerman J, Whittaker KC, Friedman M, Chertkow H.

Brain Stimul. 2020 Jan - Feb;13(1):89-95. doi: 10.1016/j.brs.2019.08.010. Epub 2019 Aug 17.


The Use of Random Forests to Classify Amyloid Brain PET.

Zukotynski K, Gaudet V, Kuo PH, Adamo S, Goubran M, Scott C, Bocti C, Borrie M, Chertkow H, Frayne R, Hsiung R, Laforce R Jr, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Sossi V, Thiel A, Soucy JP, Tardif JC, Black SE.

Clin Nucl Med. 2019 Oct;44(10):784-788. doi: 10.1097/RLU.0000000000002747.


Subcortical amyloid relates to cortical morphology in cognitively normal individuals.

Rahayel S, Bocti C, Sévigny Dupont P, Joannette M, Lavallée MM, Nikelski J, Chertkow H, Joubert S.

Eur J Nucl Med Mol Imaging. 2019 Oct;46(11):2358-2369. doi: 10.1007/s00259-019-04446-w. Epub 2019 Jul 25.


The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study.

Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ.

Can J Neurol Sci. 2019 Sep;46(5):499-511. doi: 10.1017/cjn.2019.27. Epub 2019 Jul 16.


Subcortical amyloid load is associated with shape and volume in cognitively normal individuals.

Rahayel S, Bocti C, Sévigny Dupont P, Joannette M, Lavallée MM, Nikelski J, Chertkow H, Joubert S.

Hum Brain Mapp. 2019 Sep;40(13):3951-3965. doi: 10.1002/hbm.24680. Epub 2019 May 30.


Development and validation of a salivary tau biomarker in Alzheimer's disease.

Pekeles H, Qureshi HY, Paudel HK, Schipper HM, Gornistky M, Chertkow H.

Alzheimers Dement (Amst). 2018 Apr 21;11:53-60. doi: 10.1016/j.dadm.2018.03.003. eCollection 2019 Dec.


National Neuroinformatics Framework for Canadian Consortium on Neurodegeneration in Aging (CCNA).

Mohaddes Z, Das S, Abou-Haidar R, Safi-Harab M, Blader D, Callegaro J, Henri-Bellemare C, Tunteng JF, Evans L, Campbell T, Lo D, Morin PE, Whitehead V, Chertkow H, Evans AC.

Front Neuroinform. 2018 Dec 21;12:85. doi: 10.3389/fninf.2018.00085. eCollection 2018.


The Frontotemporal Dementia versus Primary Psychiatric Disorder (FTD versus PPD) Checklist: A Bedside Clinical Tool to Identify Behavioral Variant FTD in Patients with Late-Onset Behavioral Changes.

Ducharme S, Pearl-Dowler L, Gossink F, McCarthy J, Lai J, Dickerson BC, Chertkow H, Rapin L, Vijverberg E, Krudop W, Dols A, Pijnenburg Y.

J Alzheimers Dis. 2019;67(1):113-124. doi: 10.3233/JAD-180839.


Donepezil for gait and falls in mild cognitive impairment: a randomized controlled trial.

Montero-Odasso M, Speechley M, Chertkow H, Sarquis-Adamson Y, Wells J, Borrie M, Vanderhaeghe L, Zou GY, Fraser S, Bherer L, Muir-Hunter SW.

Eur J Neurol. 2019 Apr;26(4):651-659. doi: 10.1111/ene.13872. Epub 2018 Dec 26.


An Action Plan to Face the Challenge of Dementia: INTERNATIONAL STATEMENT ON DEMENTIA from IAP for Health.

Chertkow H.

J Prev Alzheimers Dis. 2018;5(3):207-212. doi: 10.14283/jpad.2018.27.


Motor and Cognitive Trajectories Before Dementia: Results from Gait and Brain Study.

Montero-Odasso M, Speechley M, Muir-Hunter SW, Sarquis-Adamson Y, Sposato LA, Hachinski V, Borrie M, Wells J, Black A, Sejdić E, Bherer L, Chertkow H; Canadian Gait and Cognition Network.

J Am Geriatr Soc. 2018 Sep;66(9):1676-1683. doi: 10.1111/jgs.15341. Epub 2018 Apr 2.


Structural brain differences between monolingual and multilingual patients with mild cognitive impairment and Alzheimer disease: Evidence for cognitive reserve.

Duncan HD, Nikelski J, Pilon R, Steffener J, Chertkow H, Phillips NA.

Neuropsychologia. 2018 Jan 31;109:270-282. doi: 10.1016/j.neuropsychologia.2017.12.036. Epub 2017 Dec 26.


Integrating sex and gender into neurodegeneration research: A six-component strategy.

Tierney MC, Curtis AF, Chertkow H, Rylett RJ.

Alzheimers Dement (N Y). 2017 Nov 22;3(4):660-667. doi: 10.1016/j.trci.2017.10.006. eCollection 2017 Nov.


Inferior parietal transcranial direct current stimulation with training improves cognition in anomic Alzheimer's disease and frontotemporal dementia.

Roncero C, Kniefel H, Service E, Thiel A, Probst S, Chertkow H.

Alzheimers Dement (N Y). 2017 Mar 24;3(2):247-253. doi: 10.1016/j.trci.2017.03.003. eCollection 2017 Jun.


Application of calibrated fMRI in Alzheimer's disease.

Lajoie I, Nugent S, Debacker C, Dyson K, Tancredi FB, Badhwar A, Belleville S, Deschaintre Y, Bellec P, Doyon J, Bocti C, Gauthier S, Arnold D, Kergoat MJ, Chertkow H, Monchi O, Hoge RD.

Neuroimage Clin. 2017 May 16;15:348-358. doi: 10.1016/j.nicl.2017.05.009. eCollection 2017.


A dataset of multiresolution functional brain parcellations in an elderly population with no or mild cognitive impairment.

Tam A, Dansereau C, Badhwar A, Orban P, Belleville S, Chertkow H, Dagher A, Hanganu A, Monchi O, Rosa-Neto P, Shmuel A, Breitner J, Bellec P; Alzheimer׳s Disease Neuroimaging Initiative.

Data Brief. 2016 Nov 18;9:1122-1129. eCollection 2016 Dec.


Common Effects of Amnestic Mild Cognitive Impairment on Resting-State Connectivity Across Four Independent Studies.

Tam A, Dansereau C, Badhwar A, Orban P, Belleville S, Chertkow H, Dagher A, Hanganu A, Monchi O, Rosa-Neto P, Shmuel A, Wang S, Breitner J, Bellec P; Alzheimer's Disease Neuroimaging Initiative.

Front Aging Neurosci. 2015 Dec 24;7:242. doi: 10.3389/fnagi.2015.00242. eCollection 2015.


Patterns of Cognitive Decline Prior to Dementia in Persons with Mild Cognitive Impairment.

Cloutier S, Chertkow H, Kergoat MJ, Gauthier S, Belleville S.

J Alzheimers Dis. 2015;47(4):901-13. doi: 10.3233/JAD-142910.


Delaying onset of dementia: are two languages enough?

Freedman M, Alladi S, Chertkow H, Bialystok E, Craik FI, Phillips NA, Duggirala V, Raju SB, Bak TH.

Behav Neurol. 2014;2014:808137. doi: 10.1155/2014/808137. Epub 2014 May 18. Review.


Montreal Cognitive Assessment Memory Index Score (MoCA-MIS) as a predictor of conversion from mild cognitive impairment to Alzheimer's disease.

Julayanont P, Brousseau M, Chertkow H, Phillips N, Nasreddine ZS.

J Am Geriatr Soc. 2014 Apr;62(4):679-84. doi: 10.1111/jgs.12742. Epub 2014 Mar 17.


Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: consensus from the Canadian conference on diagnosis of dementia.

Chertkow H, Feldman HH, Jacova C, Massoud F.

Alzheimers Res Ther. 2013 Jul 8;5(Suppl 1):S2. doi: 10.1186/alzrt198. Epub 2013 Jul 8.


Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma.

Bhatnagar S, Chertkow H, Schipper HM, Yuan Z, Shetty V, Jenkins S, Jones T, Wang E.

Front Mol Neurosci. 2014 Feb 4;7:2. doi: 10.3389/fnmol.2014.00002. eCollection 2014.


Progressive supranuclear palsy in a family with TDP-43 pathology.

Kertesz A, Finger E, Murrell J, Chertkow H, Ang LC, Baker M, Ravenscroft T, Rademakers R, Munoz DG.

Neurocase. 2015;21(2):178-84. doi: 10.1080/13554794.2013.878729. Epub 2014 Jan 30.


Visual selective attention in amnestic mild cognitive impairment.

McLaughlin PM, Anderson ND, Rich JB, Chertkow H, Murtha SJ.

J Gerontol B Psychol Sci Soc Sci. 2014 Nov;69(6):881-91. doi: 10.1093/geronb/gbt077. Epub 2013 Aug 23.


Does a positive Pittsburgh Compound B scan in a patient with dementia equal Alzheimer disease?

Ducharme S, Guiot MC, Nikelski J, Chertkow H.

JAMA Neurol. 2013 Jul;70(7):912-4. doi: 10.1001/jamaneurol.2013.420.


Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4).

Gauthier S, Patterson C, Chertkow H, Gordon M, Herrmann N, Rockwood K, Rosa-Neto P, Soucy JP.

Can Geriatr J. 2012 Dec;15(4):120-6. doi: 10.5770/cgj.15.49. Epub 2012 Dec 4.


4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia.

Gauthier S, Patterson C, Chertkow H, Gordon M, Herrmann N, Rockwood K, Rosa-Neto P, Soucy JP; CCCDTD4 participants.

Can J Neurol Sci. 2012 Nov;39(6 Suppl 5):S1-8. English, French. No abstract available.


Word reading threshold and mild cognitive impairment: a validation study.

Arsenault-Lapierre G, Bergman H, Chertkow H.

BMC Geriatr. 2012 Jul 24;12:38. doi: 10.1186/1471-2318-12-38.


Effects of anosognosia on perceived stress and cortisol levels in Alzheimer's disease.

Arsenault-Lapierre G, Whitehead V, Lupien S, Chertkow H.

Int J Alzheimers Dis. 2012;2012:209570. doi: 10.1155/2012/209570. Epub 2012 Mar 1.


Autobiographical memory in mild cognitive impairment and Alzheimer's disease: a comparison between the Levine and Kopelman interview methodologies.

Barnabe A, Whitehead V, Pilon R, Arsenault-Lapierre G, Chertkow H.

Hippocampus. 2012 Sep;22(9):1809-25. doi: 10.1002/hipo.22015. Epub 2012 Apr 10.


Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample.

Nasreddine ZS, Phillips N, Chertkow H.

Neurology. 2012 Mar 6;78(10):765-6; author reply 766. doi: 10.1212/01.wnl.0000413072.54070.a3. No abstract available.


The profile of executive functioning in amnestic mild cognitive impairment: disproportionate deficits in inhibitory control.

Johns EK, Phillips NA, Belleville S, Goupil D, Babins L, Kelner N, Ska B, Gilbert B, Massoud F, de Boysson C, Duncan HD, Chertkow H.

J Int Neuropsychol Soc. 2012 May;18(3):541-55. doi: 10.1017/S1355617712000069. Epub 2012 Feb 28.


Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM; Alzheimer's Disease Neuroimaging Initiative; Pediatric Imaging, Neurocognition, and Genetics Study, Weiner M, Aisen P, Petersen R, Jack CR Jr, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Ging-Yuek, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Longmire CF, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3985-90. doi: 10.1073/pnas.1105829109. Epub 2012 Feb 16.


The relation between depressive symptoms and semantic memory in amnestic mild cognitive impairment and in late-life depression.

Brunet J, Hudon C, Macoir J, Belleville S, Rousseau F, Bouchard RW, Verret L, Chertkow H, Chayer C, Kergoat MJ, Joubert S.

J Int Neuropsychol Soc. 2011 Sep;17(5):865-74. doi: 10.1017/S1355617711000877. Epub 2011 Jul 5.


The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH.

Alzheimers Dement. 2011 May;7(3):263-9. doi: 10.1016/j.jalz.2011.03.005. Epub 2011 Apr 21.


Mild cognitive impairment subcategories depend on the source of norms.

Arsenault-Lapierre G, Whitehead V, Belleville S, Massoud F, Bergman H, Chertkow H.

J Clin Exp Neuropsychol. 2011 Jun;33(5):596-603. doi: 10.1080/13803395.2010.547459. Epub 2011 Feb 6.


False recognition in Lewy-body disease and frontotemporal dementia.

de Boysson C, Belleville S, Phillips NA, Johns EK, Goupil D, Souchay C, Bouchard R, Chertkow H.

Brain Cogn. 2011 Mar;75(2):111-8. doi: 10.1016/j.bandc.2010.10.011. Epub 2010 Nov 20.


Task switching performance reveals heterogeneity amongst patients with mild cognitive impairment.

Sinai M, Phillips NA, Chertkow H, Kabani NJ.

Neuropsychology. 2010 Nov;24(6):757-74. doi: 10.1037/a0020314.


Multilingualism (but not always bilingualism) delays the onset of Alzheimer disease: evidence from a bilingual community.

Chertkow H, Whitehead V, Phillips N, Wolfson C, Atherton J, Bergman H.

Alzheimer Dis Assoc Disord. 2010 Apr-Jun;24(2):118-25. doi: 10.1097/WAD.0b013e3181ca1221.


A randomized controlled trial of estrogen treatment in men with mild cognitive impairment.

Sherwin BB, Chertkow H, Schipper H, Nasreddine Z.

Neurobiol Aging. 2011 Oct;32(10):1808-17. doi: 10.1016/j.neurobiolaging.2009.11.002. Epub 2009 Dec 9.


Executive functions in frontotemporal dementia and Lewy body dementia.

Johns EK, Phillips NA, Belleville S, Goupil D, Babins L, Kelner N, Ska B, Gilbert B, Inglis G, Panisset M, de Boysson C, Chertkow H.

Neuropsychology. 2009 Nov;23(6):765-77. doi: 10.1037/a0016792.


MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders.

Maes OC, Chertkow HM, Wang E, Schipper HM.

Curr Genomics. 2009 May;10(3):154-68. doi: 10.2174/138920209788185252.


Dual-tasking and gait in people with mild cognitive impairment. The effect of working memory.

Montero-Odasso M, Bergman H, Phillips NA, Wong CH, Sourial N, Chertkow H.

BMC Geriatr. 2009 Sep 1;9:41. doi: 10.1186/1471-2318-9-41.


Methodology for discovery of Alzheimer's disease blood-based biomarkers.

Maes OC, Schipper HM, Chertkow HM, Wang E.

J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):636-45. doi: 10.1093/gerona/glp045. Epub 2009 Apr 14.


Near-infrared spectroscopy of blood plasma for diagnosis of sporadic Alzheimer's disease.

Burns DH, Rosendahl S, Bandilla D, Maes OC, Chertkow HM, Schipper HM.

J Alzheimers Dis. 2009;17(2):391-7. doi: 10.3233/JAD-2009-1053.


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