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Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial Connexins as a therapeutic target.

Sauvet F, Erblang M, Gomez-Merino D, Rabat A, Guillard M, Dubourdieu H, Lefloch H, Drogou C, Van Beers P, Bougard C, Bourrrilhon C, Arnal P, Rein W, Mouthon F, Brunner-Ferber F, Leger D, Dauvilliers Y, Chennaoui M, Charvériat M.

Br J Clin Pharmacol. 2019 Aug 16. doi: 10.1111/bcp.14098. [Epub ahead of print]


Limited Benefit of Sleep Extension on Cognitive Deficits During Total Sleep Deprivation: Illustration With Two Executive Processes.

Rabat A, Arnal PJ, Monnard H, Erblang M, Van Beers P, Bougard C, Drogou C, Guillard M, Sauvet F, Leger D, Gomez-Merino D, Chennaoui M.

Front Neurosci. 2019 Jun 19;13:591. doi: 10.3389/fnins.2019.00591. eCollection 2019.


The association between physical and mental chronic conditions and napping.

Léger D, Torres MJ, Bayon V, Hercberg S, Galan P, Chennaoui M, Andreeva VA.

Sci Rep. 2019 Feb 11;9(1):1795. doi: 10.1038/s41598-018-37355-3.


Preconditioning Strategy in Rugby-7s Players: Beneficial or Detrimental?

Marrier B, Durguerian A, Robineau J, Chennaoui M, Sauvet F, Servonnet A, Piscione J, Mathieu B, Peeters A, Lacome M, Morin JB, Le Meur Y.

Int J Sports Physiol Perform. 2018 Dec 20:1-26. doi: 10.1123/ijspp.2018-0505. [Epub ahead of print]


Mouse Gambling Task reveals differential effects of acute sleep debt on decision-making and associated neurochemical changes.

Pittaras E, Callebert J, Dorey R, Chennaoui M, Granon S, Rabat A.

Sleep. 2018 Nov 1;41(11). doi: 10.1093/sleep/zsy168.


Larger strength losses and muscle activation deficits in plantar flexors induced by backward downhill in reference to distance-matched forward uphill treadmill walk.

Girard O, Banzet S, Koulmann N, Chennaoui M, Drogou C, Chalabi H, Racinais S.

Eur J Sport Sci. 2018 Nov;18(10):1346-1356. doi: 10.1080/17461391.2018.1497091. Epub 2018 Jul 17.


Lengthening of the photoperiod influences sleep characteristics before and during total sleep deprivation in rat.

Sauvet F, Gomez-Merino D, Dorey R, Ciret S, Gallopin T, Drogou C, Arnal PJ, Chennaoui M.

J Sleep Res. 2019 Jun;28(3):e12709. doi: 10.1111/jsr.12709. Epub 2018 Jun 4.


Shift work, night work and sleep disorders among pastry cookers and shopkeepers in France: a cross-sectional survey.

Pepin E, Gillet P, Sauvet F, Gomez-Merino D, Thaon I, Chennaoui M, Leger D.

BMJ Open. 2018 May 9;8(5):e019098. doi: 10.1136/bmjopen-2017-019098.


Daytime microsleeps during 7 days of sleep restriction followed by 13 days of sleep recovery in healthy young adults.

Bougard C, Gomez-Merino D, Rabat A, Arnal P, Van Beers P, Guillard M, Léger D, Sauvet F, Chennaoui M.

Conscious Cogn. 2018 May;61:1-12. doi: 10.1016/j.concog.2018.03.008. Epub 2018 Apr 6.


Performance of an Ambulatory Dry-EEG Device for Auditory Closed-Loop Stimulation of Sleep Slow Oscillations in the Home Environment.

Debellemaniere E, Chambon S, Pinaud C, Thorey V, Dehaene D, Léger D, Chennaoui M, Arnal PJ, Galtier MN.

Front Hum Neurosci. 2018 Mar 8;12:88. doi: 10.3389/fnhum.2018.00088. eCollection 2018.


Slow-wave sleep: From the cell to the clinic.

Léger D, Debellemaniere E, Rabat A, Bayon V, Benchenane K, Chennaoui M.

Sleep Med Rev. 2018 Oct;41:113-132. doi: 10.1016/j.smrv.2018.01.008. Epub 2018 Feb 5. Review.


Sleep and biological parameters in professional burnout: A psychophysiological characterization.

Metlaine A, Sauvet F, Gomez-Merino D, Boucher T, Elbaz M, Delafosse JY, Leger D, Chennaoui M.

PLoS One. 2018 Jan 31;13(1):e0190607. doi: 10.1371/journal.pone.0190607. eCollection 2018.


Using relaxation techniques to improve sleep during naps.

Debellemaniere E, Gomez-Merino D, Erblang M, Dorey R, Genot M, Perreaut-Pierre E, Pisani A, Rocco L, Sauvet F, Léger D, Rabat A, Chennaoui M.

Ind Health. 2018 Jun 1;56(3):220-227. doi: 10.2486/indhealth.2017-0092. Epub 2018 Jan 13.


Hyperactivity of the Sympatho-Adrenomedullary System Without Any Modification of the Hypothalamic-Pituitary-Adrenal Axis After Food Restriction Among High-Level Weightlifters.

Durguerian A, Filaire E, Drogou C, Sauvet F, Bougard C, Chennaoui M.

J Strength Cond Res. 2018 Jun;32(6):1643-1655. doi: 10.1519/JSC.0000000000002038.


Changes of Cerebral and/or Peripheral Adenosine A₁ Receptor and IGF-I Concentrations under Extended Sleep Duration in Rats.

Chennaoui M, Arnal PJ, Dorey R, Sauvet F, Ciret S, Gallopin T, Leger D, Drogou C, Gomez-Merino D.

Int J Mol Sci. 2017 Nov 17;18(11). pii: E2439. doi: 10.3390/ijms18112439.


Leukocyte Expression of Type 1 and Type 2 Purinergic Receptors and Pro-Inflammatory Cytokines during Total Sleep Deprivation and/or Sleep Extension in Healthy Subjects.

Chennaoui M, Arnal PJ, Drogou C, Leger D, Sauvet F, Gomez-Merino D.

Front Neurosci. 2017 May 2;11:240. doi: 10.3389/fnins.2017.00240. eCollection 2017.


Food restriction alters salivary cortisol and α-amylase responses to a simulated weightlifting competition without significant performance modification.

Durguerian A, Filaire E, Drogou C, Bougard C, Chennaoui M.

J Sports Sci. 2018 Mar;36(5):536-544. doi: 10.1080/02640414.2017.1322708. Epub 2017 May 5.


The homeostatic and circadian sleep recovery responses after total sleep deprivation in mice.

Dispersyn G, Sauvet F, Gomez-Merino D, Ciret S, Drogou C, Leger D, Gallopin T, Chennaoui M.

J Sleep Res. 2017 Oct;26(5):531-538. doi: 10.1111/jsr.12541. Epub 2017 Apr 20.


Sound level intensity severely disrupts sleep in ventilated ICU patients throughout a 24-h period: a preliminary 24-h study of sleep stages and associated sound levels.

Elbaz M, Léger D, Sauvet F, Champigneulle B, Rio S, Strauss M, Chennaoui M, Guilleminault C, Mira JP.

Ann Intensive Care. 2017 Dec;7(1):25. doi: 10.1186/s13613-017-0248-7. Epub 2017 Mar 3.


Protective effects of exercise training on endothelial dysfunction induced by total sleep deprivation in healthy subjects.

Sauvet F, Arnal PJ, Tardo-Dino PE, Drogou C, Van Beers P, Bougard C, Rabat A, Dispersyn G, Malgoyre A, Leger D, Gomez-Merino D, Chennaoui M.

Int J Cardiol. 2017 Apr 1;232:76-85. doi: 10.1016/j.ijcard.2017.01.049. Epub 2017 Jan 5.


Association between insomnia symptoms, job strain and burnout syndrome: a cross-sectional survey of 1300 financial workers.

Metlaine A, Sauvet F, Gomez-Merino D, Elbaz M, Delafosse JY, Leger D, Chennaoui M.

BMJ Open. 2017 Jan 13;7(1):e012816. doi: 10.1136/bmjopen-2016-012816.


Development of a specific index to detect malnutrition in athletes: Validity in weight class or intermittent fasted athletes.

Desgorces FD, Moinard C, Chennaoui M, Toussaint JF, Petibois C, Noirez P.

Biochim Open. 2016 Nov 23;4:1-7. doi: 10.1016/j.biopen.2016.10.001. eCollection 2017 Jun.


Sleep extension increases IGF-I concentrations before and during sleep deprivation in healthy young men.

Chennaoui M, Arnal PJ, Drogou C, Sauvet F, Gomez-Merino D.

Appl Physiol Nutr Metab. 2016 Sep;41(9):963-70. doi: 10.1139/apnm-2016-0110. Epub 2016 May 13.


Differential Kinetics in Alteration and Recovery of Cognitive Processes from a Chronic Sleep Restriction in Young Healthy Men.

Rabat A, Gomez-Merino D, Roca-Paixao L, Bougard C, Van Beers P, Dispersyn G, Guillard M, Bourrilhon C, Drogou C, Arnal PJ, Sauvet F, Leger D, Chennaoui M.

Front Behav Neurosci. 2016 May 23;10:95. doi: 10.3389/fnbeh.2016.00095. eCollection 2016.


Sleep Extension before Sleep Loss: Effects on Performance and Neuromuscular Function.

Arnal PJ, Lapole T, Erblang M, Guillard M, Bourrilhon C, Léger D, Chennaoui M, Millet GY.

Med Sci Sports Exerc. 2016 Aug;48(8):1595-603. doi: 10.1249/MSS.0000000000000925.


Stress Biomarkers, Mood States, and Sleep during a Major Competition: "Success" and "Failure" Athlete's Profile of High-Level Swimmers.

Chennaoui M, Bougard C, Drogou C, Langrume C, Miller C, Gomez-Merino D, Vergnoux F.

Front Physiol. 2016 Mar 14;7:94. doi: 10.3389/fphys.2016.00094. eCollection 2016.


Individual behavioral and neurochemical markers of unadapted decision-making processes in healthy inbred mice.

Pittaras E, Callebert J, Chennaoui M, Rabat A, Granon S.

Brain Struct Funct. 2016 Dec;221(9):4615-4629. Epub 2016 Feb 10.


Weight Loss, Performance and Psychological Related States in High-level Weightlifters.

Durguerian A, Bougard C, Drogou C, Sauvet F, Chennaoui M, Filaire E.

Int J Sports Med. 2016 Mar;37(3):230-8. doi: 10.1055/s-0035-1555852. Epub 2015 Dec 23.


Effect of Sleep Extension on the Subsequent Testosterone, Cortisol and Prolactin Responses to Total Sleep Deprivation and Recovery.

Arnal PJ, Drogou C, Sauvet F, Regnauld J, Dispersyn G, Faraut B, Millet GY, Leger D, Gomez-Merino D, Chennaoui M.

J Neuroendocrinol. 2016 Feb;28(2):12346. doi: 10.1111/jne.12346.


Salivary Hormones Response to Preparation and Pre-competitive Training of World-class Level Athletes.

Guilhem G, Hanon C, Gendreau N, Bonneau D, Guével A, Chennaoui M.

Front Physiol. 2015 Nov 16;6:333. doi: 10.3389/fphys.2015.00333. eCollection 2015.


Effects of exercise on brain and peripheral inflammatory biomarkers induced by total sleep deprivation in rats.

Chennaoui M, Gomez-Merino D, Drogou C, Geoffroy H, Dispersyn G, Langrume C, Ciret S, Gallopin T, Sauvet F.

J Inflamm (Lond). 2015 Sep 30;12:56. doi: 10.1186/s12950-015-0102-3. eCollection 2015.


Benefits of Sleep Extension on Sustained Attention and Sleep Pressure Before and During Total Sleep Deprivation and Recovery.

Arnal PJ, Sauvet F, Leger D, van Beers P, Bayon V, Bougard C, Rabat A, Millet GY, Chennaoui M.

Sleep. 2015 Dec 1;38(12):1935-43. doi: 10.5665/sleep.5244.


Sleeping under the Ocean: Despite Total Isolation, Nuclear Submariners Maintain Their Sleep and Wake Patterns throughout Their Under Sea Mission.

Trousselard M, Leger D, van Beers P, Coste O, Vicard A, Pontis J, Crosnier SN, Chennaoui M.

PLoS One. 2015 May 27;10(5):e0126721. doi: 10.1371/journal.pone.0126721. eCollection 2015.


Vascular response to 1 week of sleep restriction in healthy subjects. A metabolic response?

Sauvet F, Drogou C, Bougard C, Arnal PJ, Dispersyn G, Bourrilhon C, Rabat A, Van Beers P, Gomez-Merino D, Faraut B, Leger D, Chennaoui M.

Int J Cardiol. 2015;190:246-55. doi: 10.1016/j.ijcard.2015.04.119. Epub 2015 Apr 16.


Napping reverses increased pain sensitivity due to sleep restriction.

Faraut B, Léger D, Medkour T, Dubois A, Bayon V, Chennaoui M, Perrot S.

PLoS One. 2015 Feb 27;10(2):e0117425. doi: 10.1371/journal.pone.0117425. eCollection 2015.


Effect of acute sleep deprivation and recovery on Insulin-like Growth Factor-I responses and inflammatory gene expression in healthy men.

Chennaoui M, Drogou C, Sauvet F, Gomez-Merino D, Scofield DE, Nindl BC.

Eur Cytokine Netw. 2014 Jul-Sep;25(3):52-7. doi: 10.1684/ecn.2014.0356.


Sleep and exercise: a reciprocal issue?

Chennaoui M, Arnal PJ, Sauvet F, Léger D.

Sleep Med Rev. 2015 Apr;20:59-72. doi: 10.1016/j.smrv.2014.06.008. Epub 2014 Jun 30. Review.


Sleep debt and obesity.

Bayon V, Leger D, Gomez-Merino D, Vecchierini MF, Chennaoui M.

Ann Med. 2014 Aug;46(5):264-72. doi: 10.3109/07853890.2014.931103. Epub 2014 Jul 11. Review.


In-flight automatic detection of vigilance states using a single EEG channel.

Sauvet F, Bougard C, Coroenne M, Lely L, Van Beers P, Elbaz M, Guillard M, Leger D, Chennaoui M.

IEEE Trans Biomed Eng. 2014 Dec;61(12):2840-7. doi: 10.1109/TBME.2014.2331189. Epub 2014 Jun 24.


Total sleep deprivation alters endothelial function in rats: a nonsympathetic mechanism.

Sauvet F, Florence G, Van Beers P, Drogou C, Lagrume C, Chaumes C, Ciret S, Leftheriotis G, Chennaoui M.

Sleep. 2014 Mar 1;37(3):465-73. doi: 10.5665/sleep.3476.


Insomnia and accidents: cross-sectional study (EQUINOX) on sleep-related home, work and car accidents in 5293 subjects with insomnia from 10 countries.

Léger D, Bayon V, Ohayon MM, Philip P, Ement P, Metlaine A, Chennaoui M, Faraut B.

J Sleep Res. 2014 Apr;23(2):143-52. doi: 10.1111/jsr.12104. Epub 2013 Nov 15.


Changes in circulating microRNAs levels with exercise modality.

Banzet S, Chennaoui M, Girard O, Racinais S, Drogou C, Chalabi H, Koulmann N.

J Appl Physiol (1985). 2013 Nov 1;115(9):1237-44. doi: 10.1152/japplphysiol.00075.2013. Epub 2013 Aug 15.


Effect of one night of sleep loss on changes in tumor necrosis factor alpha (TNF-α) levels in healthy men.

Chennaoui M, Sauvet F, Drogou C, Van Beers P, Langrume C, Guillard M, Gourby B, Bourrilhon C, Florence G, Gomez-Merino D.

Cytokine. 2011 Nov;56(2):318-24. doi: 10.1016/j.cyto.2011.06.002. Epub 2011 Jul 6.


Acetylcholine chloride as a potential source of variability in the study of cutaneous vascular function in man.

Sauvet F, Mahé G, Chennaoui M, Langrume C, Vasseur M, Abraham P, Leftheriotis G.

Microvasc Res. 2011 Sep;82(2):190-7. doi: 10.1016/j.mvr.2011.05.001. Epub 2011 May 12.


Cytokine content in lymphoid and white adipose tissues after repeated CpG oligodeoxynucleotide administration in trained rats.

Chennaoui M, Drogou C, Carpentier AF, Guezennec CY, Gomez-Merino D.

Vaccine. 2010 Feb 17;28(7):1814-8. doi: 10.1016/j.vaccine.2009.12.003. Epub 2009 Dec 16.


Effect of acute sleep deprivation on vascular function in healthy subjects.

Sauvet F, Leftheriotis G, Gomez-Merino D, Langrume C, Drogou C, Van Beers P, Bourrilhon C, Florence G, Chennaoui M.

J Appl Physiol (1985). 2010 Jan;108(1):68-75. doi: 10.1152/japplphysiol.00851.2009. Epub 2009 Nov 12.


Influence of protein- versus carbohydrate-enriched feedings on physiological responses during an ultraendurance climbing race.

Bourrilhon C, Lepers R, Philippe M, Beers PV, Chennaoui M, Drogou C, Beauvieux MC, Burnat P, Guezennec CY, Gomez-Merino D.

Horm Metab Res. 2010 Jan;42(1):31-7. doi: 10.1055/s-0029-1237727. Epub 2009 Oct 9.


Effects of Ramadan fasting on physical performance and metabolic, hormonal, and inflammatory parameters in middle-distance runners.

Chennaoui M, Desgorces F, Drogou C, Boudjemaa B, Tomaszewski A, Depiesse F, Burnat P, Chalabi H, Gomez-Merino D.

Appl Physiol Nutr Metab. 2009 Aug;34(4):587-94. doi: 10.1139/H09-014.


Whole body immersion and hydromineral homeostasis: effect of water temperature.

Jimenez C, Regnard J, Robinet C, Mourot L, Gomez-Merino D, Chennaoui M, Jammes Y, Dumoulin G, Desruelle AV, Melin B.

Eur J Appl Physiol. 2010 Jan;108(1):49-58. doi: 10.1007/s00421-009-1187-2. Epub 2009 Sep 16.


Energy expenditure during an ultraendurance alpine climbing race.

Bourrilhon C, Philippe M, Chennaoui M, Van Beers P, Lepers R, Dussault C, Guezennec CY, Gomez-Merino D.

Wilderness Environ Med. 2009 Fall;20(3):225-33. doi: 10.1580/08-WEME-OR-217R3.1.


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